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14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81525]
Superfamily:   14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81524]
Families:   14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81523]


Superfamily statistics
Genomes (468) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 617 671 7
Proteins 613 670 7


Functional annotation
General category Metabolism
Detailed category Energy

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)generation of precursor metabolites and energy0.000000060460.00000009774Moderately InformativeDirect
Cellular Component (CC)membrane0.0000038530.0001522Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.000086080.0001684Least InformativeDirect
Cellular Component (CC)protein complex0.000012710.0001694Least InformativeDirect
Cellular Component (CC)cytoplasmic part0.00025550.00004223Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.0002910.01406Least InformativeInherited
Cellular Component (CC)organelle membrane0.00000015010.0000002994Moderately InformativeDirect
Cellular Component (CC)organelle envelope0.000000011160.0000000156Moderately InformativeDirect
Cellular Component (CC)mitochondrial part0.0000000060560.00000001164Moderately InformativeDirect
Cellular Component (CC)membrane protein complex0.000046130.000002978Moderately InformativeDirect
Cellular Component (CC)intrinsic component of membrane0.0051420.02269Moderately InformativeInherited
Cellular Component (CC)mitochondrial respiratory chain0.0000028770.00000197InformativeDirect
Cellular Component (CC)cytochrome complex0.000000000016540.0000000000006234InformativeDirect
Cellular Component (CC)inner mitochondrial membrane protein complex0.00032590.00003957InformativeDirect
Cellular Component (CC)oxidoreductase complex0.00000000001450.0000000000157InformativeDirect
Cellular Component (CC)transporter complex0.00000000000006160.00000000003346InformativeDirect
Cellular Component (CC)respiratory chain complex0.0068260.0005628InformativeInherited
Cellular Component (CC)mitochondrial respiratory chain complex III0.0000000000018720.000000000006Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) generation of precursor metabolites and energy 0.00000009774 Moderately Informative Direct
Cellular Component (CC) membrane 0.0001522 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0001684 Least Informative Direct
Cellular Component (CC) protein complex 0.0001694 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.00004223 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.01406 Least Informative Inherited
Cellular Component (CC) organelle membrane 0.0000002994 Moderately Informative Direct
Cellular Component (CC) organelle envelope 0.0000000156 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 0.00000001164 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0.000002978 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0.02269 Moderately Informative Inherited
Cellular Component (CC) mitochondrial respiratory chain 0.00000197 Informative Direct
Cellular Component (CC) cytochrome complex 0.0000000000006234 Informative Direct
Cellular Component (CC) inner mitochondrial membrane protein complex 0.00003957 Informative Direct
Cellular Component (CC) respiratory chain complex 0.0005628 Informative Direct
Cellular Component (CC) oxidoreductase complex 0.0000000000157 Informative Direct
Cellular Component (CC) transporter complex 0.00000000003346 Informative Direct
Cellular Component (CC) mitochondrial respiratory chain complex III 0.000000000006 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processElectron transport0InformativeDirect
Biological processRespiratory chain0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR003197 SSF81524 Protein matches
Abstract

The cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake [PubMed8626304]. Members of this family are integral membrane proteins and contain a protoheame IX centre B558.

Cytochrome bd may play an important role in microaerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae, where it is expressed under all conditions that permit diazotrophy [PubMed9274021].

The 14 kDa (or VI) subunit of the complex is not directly involved in electron transfer, but has a role in assembly of the complex [PubMed7770525].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]