SUPERFAMILY 1.75 HMM library and genome assignments server


14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81525]
Superfamily:   14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81524]
Families:   14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) [ 81523]


Superfamily statistics
Genomes (456) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 599 671 7
Proteins 595 670 7


Functional annotation
General category Metabolism
Detailed category Energy

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular component organization or biogenesis0.0028430.03313Least InformativeInherited
Biological Process (BP)macromolecular complex subunit organization6.534e-063.53e-05Moderately InformativeDirect
Biological Process (BP)cellular component biogenesis3.327e-050.0002423Moderately InformativeDirect
Biological Process (BP)protein complex assembly6.193e-071.01e-06InformativeDirect
Cellular Component (CC)membrane1.067e-050.0001099Least InformativeDirect
Cellular Component (CC)intracellular organelle part2.202e-050.0006602Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.0036570.009512Least InformativeInherited
Cellular Component (CC)protein complex0.0011360.00743Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.0033410.001285Least InformativeInherited
Cellular Component (CC)organelle membrane2.756e-082.827e-08Moderately InformativeDirect
Cellular Component (CC)organelle envelope1.082e-102.066e-10Moderately InformativeDirect
Cellular Component (CC)mitochondrial part4.418e-118.629e-11Moderately InformativeDirect
Cellular Component (CC)mitochondrial membrane part7.337e-071.227e-08InformativeDirect
Cellular Component (CC)respiratory chain1.138e-102.652e-12InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0.03313 Least Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 3.53e-05 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.0002423 Moderately Informative Direct
Biological Process (BP) protein complex assembly 1.01e-06 Informative Direct
Cellular Component (CC) membrane 0.0001099 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.0006602 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.009512 Least Informative Inherited
Cellular Component (CC) protein complex 0.00743 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.001285 Least Informative Inherited
Cellular Component (CC) organelle membrane 2.827e-08 Moderately Informative Direct
Cellular Component (CC) organelle envelope 2.066e-10 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 8.629e-11 Moderately Informative Direct
Cellular Component (CC) mitochondrial membrane part 1.227e-08 Informative Direct
Cellular Component (CC) respiratory chain 2.652e-12 Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processElectron transport0InformativeDirect
Biological processRespiratory chain0Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR003197 SSF81524 Protein matches
Abstract

The cytochrome bd type terminal oxidases catalyse quinol dependent, Na+ independent oxygen uptake [PubMed8626304]. Members of this family are integral membrane proteins and contain a protoheame IX centre B558.

Cytochrome bd may play an important role in microaerobic nitrogen fixation in the enteric bacterium Klebsiella pneumoniae, where it is expressed under all conditions that permit diazotrophy [PubMed9274021].

The 14 kDa (or VI) subunit of the complex is not directly involved in electron transfer, but has a role in assembly of the complex [PubMed7770525].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the 14 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]