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Calcium ATPase, transmembrane domain M superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Calcium ATPase, transmembrane domain M [ 81666]
Superfamily:   Calcium ATPase, transmembrane domain M [ 81665]
Families:   Calcium ATPase, transmembrane domain M [ 81664]


Superfamily statistics
Genomes (3,053) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 28,062 154,840 2
Proteins 27,812 154,199 2


Functional annotation
General category coiled coil
Detailed category This is a complex coiled arrangement. The details of which will appear on this page shortly (some coiled coil details are being checked before they are included on the site). If you want to see examples of the states please click here here. If you require further details urgently please contact Owen Rackham

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect
Enzyme Commission (EC)Potassium-transporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Calcium-transporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Proton-exporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Phospholipid-translocating ATPase0Highly InformativeDirect
Enzyme Commission (EC)Copper-exporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Sodium/potassium-exchanging ATPase0Highly InformativeDirect
Enzyme Commission (EC)Cu(+) exporting ATPase0.0000000000001092Highly InformativeDirect
Enzyme Commission (EC)Cadmium-exporting ATPase0.000000000007156Highly InformativeDirect
Enzyme Commission (EC)Hydrogen/potassium-exchanging ATPase0.0000000004596Highly InformativeDirect
Enzyme Commission (EC)Zinc-exporting ATPase0.000000007355Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.5653Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0.09611Moderately InformativeInherited
Phenotypic Abnormality (PA)Neurological speech impairment0.0153InformativeInherited
Phenotypic Abnormality (PA)Dysarthria0.0009589Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal muscle physiology0.08735Moderately InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.0004833InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.0004138Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.005431Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.006088Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.123Least InformativeInherited
Worm Phenotype (WP)apoptosis variant0.00152Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.03364Moderately InformativeInherited
Worm Phenotype (WP)nicotine response variant0.006693InformativeInherited
Worm Phenotype (WP)lipid metabolism variant0.1959InformativeInherited
Worm Phenotype (WP)plasma membrane composition variant0.000000000000002222Highly InformativeDirect
Worm Phenotype (WP)seam cell morphology variant0.00000000002677Highly InformativeDirect
Worm Phenotype (WP)nicotine hypersensitive0.00000003103Highly InformativeDirect
Worm Phenotype (WP)lipid composition variant0.00001304Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)sporangium0.0001185Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0.002465Least InformativeInherited
Plant ANatomical entity (PAN)flower0.03209Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure0.04731Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.06133Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue0.0000005989InformativeDirect
Plant ANatomical entity (PAN)parenchyma cell0.000000003417Highly InformativeDirect
Plant ANatomical entity (PAN)anther0.0005633Highly InformativeDirect
Plant ANatomical entity (PAN)mesophyll1Highly InformativeInherited
Plant structure DEvelopment stage (PDE)pollen development stage0.0002825Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembrane movement of substances0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Calcium ATPase, transmembrane domain M domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Calcium ATPase, transmembrane domain M superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]