SUPERFAMILY 1.75 HMM library and genome assignments server

Please note: Superfamily is currently under maintenance and some functionality may be limited. Please bear with us as we fix these problems.


Calcium ATPase, transmembrane domain M superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Calcium ATPase, transmembrane domain M [ 81666]
Superfamily:   Calcium ATPase, transmembrane domain M [ 81665]
Families:   Calcium ATPase, transmembrane domain M [ 81664]


Superfamily statistics
Genomes (3,044) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 27,579 95,033 2
Proteins 27,339 94,861 2


Functional annotation
General category coiled coil
Detailed category This is a complex coiled arrangement. The details of which will appear on this page shortly (some coiled coil details are being checked before they are included on the site). If you want to see examples of the states please click here here. If you require further details urgently please contact Owen Rackham

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)developmental process0.060781Least InformativeInherited
Biological Process (BP)response to stimulus0.11570.03863Least InformativeInherited
Biological Process (BP)multicellular organismal process0.027040.371Least InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.000056050.00001764Moderately InformativeDirect
Biological Process (BP)system process0.000058440.0000007774Moderately InformativeDirect
Biological Process (BP)organ development0.0071740.5071Moderately InformativeInherited
Biological Process (BP)muscle system process0.00068020.04762InformativeInherited
Biological Process (BP)regulation of system process0.058640InformativeInherited
Biological Process (BP)regulation of muscle contraction0.00000002130Highly InformativeDirect
Biological Process (BP)striated muscle contraction0.000000048180.000002503Highly InformativeDirect
Biological Process (BP)neuromuscular process0.00014610.0000192Highly InformativeDirect
Cellular Component (CC)cytoplasmic part0.32080Least InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.0024650.000002592Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.00029430Moderately InformativeDirect
Cellular Component (CC)sarcoplasmic reticulum0.000032250.00000000000001473Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.000000000001706 Least Informative Direct
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.727 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.03863 Least Informative Inherited
Biological Process (BP) protein metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.371 Least Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.00001764 Moderately Informative Direct
Biological Process (BP) system process 0.0000007774 Moderately Informative Direct
Biological Process (BP) ion transport 0 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.000004436 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.0001801 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.0002615 Moderately Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0.0005165 Moderately Informative Direct
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.9782 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.0804 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.006299 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.3539 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.5071 Moderately Informative Inherited
Biological Process (BP) single-organism developmental process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.5887 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.5148 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.9524 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.9365 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound catabolic process 0.001337 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.4814 Moderately Informative Inherited
Biological Process (BP) cellular macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.1044 Moderately Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.0000001908 Informative Direct
Biological Process (BP) regulation of system process 0 Informative Direct
Biological Process (BP) transmembrane transport 0 Informative Direct
Biological Process (BP) cellular chemical homeostasis 0 Informative Direct
Biological Process (BP) lipid localization 0 Informative Direct
Biological Process (BP) metal ion transport 0.00000000003336 Informative Direct
Biological Process (BP) nucleoside monophosphate metabolic process 0.0000000006505 Informative Direct
Biological Process (BP) regulation of ion transport 0.000000001485 Informative Direct
Biological Process (BP) blood circulation 0.000000006151 Informative Direct
Biological Process (BP) purine ribonucleotide metabolic process 0.00000001272 Informative Direct
Biological Process (BP) purine ribonucleoside metabolic process 0.0000000151 Informative Direct
Biological Process (BP) glycosyl compound catabolic process 0.00000007538 Informative Direct
Biological Process (BP) organophosphate catabolic process 0.0000003808 Informative Direct
Biological Process (BP) nucleoside triphosphate metabolic process 0.0000005663 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0.000001988 Informative Direct
Biological Process (BP) cellular membrane organization 0.00000372 Informative Direct
Biological Process (BP) response to inorganic substance 0.00001482 Informative Direct
Biological Process (BP) nucleobase-containing compound catabolic process 0.00007656 Informative Direct
Biological Process (BP) regulation of body fluid levels 0.0002998 Informative Direct
Biological Process (BP) cation homeostasis 0.0003086 Informative Direct
Biological Process (BP) muscle system process 0.04762 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.3708 Informative Inherited
Biological Process (BP) response to hormone stimulus 0.5383 Informative Inherited
Biological Process (BP) response to lipid 0.6784 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.8276 Informative Inherited
Biological Process (BP) generation of neurons 0.3299 Informative Inherited
Biological Process (BP) cell projection organization 1 Informative Inherited
Biological Process (BP) embryonic organ development 0.009175 Informative Inherited
Biological Process (BP) sensory organ development 0.01202 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.542 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.1447 Informative Inherited
Biological Process (BP) anion transport 1 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) single-organism behavior 0.2135 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) cytoskeleton organization 1 Informative Inherited
Biological Process (BP) actin filament-based process 1 Informative Inherited
Biological Process (BP) gland development 0.00378 Informative Inherited
Biological Process (BP) central nervous system development 0.01119 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.3805 Informative Inherited
Biological Process (BP) intracellular signal transduction 0.945 Informative Inherited
Biological Process (BP) biological adhesion 0.5227 Informative Inherited
Biological Process (BP) regulation of lipid metabolic process 0.02896 Informative Inherited
Biological Process (BP) response to other organism 0.4751 Informative Inherited
Biological Process (BP) response to light stimulus 0.009466 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.7526 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) organ morphogenesis 0.2705 Informative Inherited
Biological Process (BP) synaptic transmission 0.2471 Informative Inherited
Biological Process (BP) regulation of muscle contraction 0 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.000002503 Highly Informative Direct
Biological Process (BP) neuromuscular process 0.0000192 Highly Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.00000000000002782 Highly Informative Direct
Biological Process (BP) organophosphate ester transport 0.000000000001058 Highly Informative Direct
Biological Process (BP) lactation 0.000000000007024 Highly Informative Direct
Biological Process (BP) negative regulation of hormone metabolic process 0.000000003932 Highly Informative Direct
Biological Process (BP) locomotory behavior 0.00000001765 Highly Informative Direct
Biological Process (BP) ATP metabolic process 0.0000001407 Highly Informative Direct
Biological Process (BP) ER-nucleus signaling pathway 0.0000003252 Highly Informative Direct
Biological Process (BP) negative regulation of lipid biosynthetic process 0.00000124 Highly Informative Direct
Biological Process (BP) response to drug 0.000001959 Highly Informative Direct
Biological Process (BP) adult behavior 0.000004196 Highly Informative Direct
Biological Process (BP) regulation of steroid biosynthetic process 0.000004269 Highly Informative Direct
Biological Process (BP) embryonic organ morphogenesis 0.000273 Highly Informative Direct
Biological Process (BP) nucleoside monophosphate catabolic process 0.0003261 Highly Informative Direct
Biological Process (BP) ear development 0.0005414 Highly Informative Direct
Biological Process (BP) cellular response to steroid hormone stimulus 0.0006579 Highly Informative Direct
Biological Process (BP) epithelial cell development 0.0548 Highly Informative Inherited
Biological Process (BP) epidermal cell differentiation 0.2405 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.08623 Highly Informative Inherited
Biological Process (BP) cellular calcium ion homeostasis 0.01734 Highly Informative Inherited
Biological Process (BP) maintenance of location 0.09477 Highly Informative Inherited
Biological Process (BP) sensory perception 0.186 Highly Informative Inherited
Biological Process (BP) monovalent inorganic cation transport 1 Highly Informative Inherited
Biological Process (BP) calcium ion transport 0.004434 Highly Informative Inherited
Biological Process (BP) transition metal ion homeostasis 0.9739 Highly Informative Inherited
Biological Process (BP) cell adhesion 1 Highly Informative Inherited
Biological Process (BP) response to toxic substance 0.001248 Highly Informative Inherited
Biological Process (BP) learning or memory 0.3481 Highly Informative Inherited
Biological Process (BP) transition metal ion transport 0.5004 Highly Informative Inherited
Biological Process (BP) retina development in camera-type eye 0.01602 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.5134 Highly Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 0.7784 Highly Informative Inherited
Biological Process (BP) neurotransmitter transport 1 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) binding 0.2223 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0 Moderately Informative Direct
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) cation binding 0.00000005936 Moderately Informative Direct
Molecular Function (MF) anion binding 0.0785 Moderately Informative Inherited
Molecular Function (MF) purine ribonucleoside binding 0 Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) active transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.000000000000003071 Informative Direct
Molecular Function (MF) nucleotide binding 0.00000000000004484 Informative Direct
Molecular Function (MF) inorganic cation transmembrane transporter activity 0.00000000005692 Informative Direct
Molecular Function (MF) ATPase activity, coupled to transmembrane movement of ions 0 Highly Informative Direct
Molecular Function (MF) ATP binding 0 Highly Informative Direct
Molecular Function (MF) calcium ion binding 0.00001549 Highly Informative Direct
Molecular Function (MF) copper ion binding 0.00002953 Highly Informative Direct
Molecular Function (MF) calcium ion transmembrane transporter activity 0.00004679 Highly Informative Direct
Molecular Function (MF) transition metal ion transmembrane transporter activity 0.000288 Highly Informative Direct
Molecular Function (MF) protein domain specific binding 0.02291 Highly Informative Inherited
Molecular Function (MF) hydrogen ion transmembrane transporter activity 0.4329 Highly Informative Inherited
Molecular Function (MF) lipid transporter activity 0.01955 Highly Informative Inherited
Molecular Function (MF) sodium ion transmembrane transporter activity 0.0951 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.000002592 Least Informative Direct
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.6288 Least Informative Inherited
Cellular Component (CC) intracellular non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.0000000000003415 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.000002087 Moderately Informative Direct
Cellular Component (CC) intrinsic to membrane 0.0004435 Moderately Informative Direct
Cellular Component (CC) Golgi apparatus 0 Informative Direct
Cellular Component (CC) vacuolar part 0.000000662 Informative Direct
Cellular Component (CC) endoplasmic reticulum membrane 0.0004722 Informative Direct
Cellular Component (CC) contractile fiber part 0.0007604 Informative Direct
Cellular Component (CC) integral to membrane 0.003206 Informative Inherited
Cellular Component (CC) intrinsic to plasma membrane 0.8483 Informative Inherited
Cellular Component (CC) sarcoplasmic reticulum 0.00000000000001473 Highly Informative Direct
Cellular Component (CC) trans-Golgi network 0.00000000000008305 Highly Informative Direct
Cellular Component (CC) sarcomere 0.000004588 Highly Informative Direct
Cellular Component (CC) sarcolemma 0.00001257 Highly Informative Direct
Cellular Component (CC) apical plasma membrane 0.00005817 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 0.0005503 Highly Informative Direct
Cellular Component (CC) cell body 0.01556 Highly Informative Inherited
Cellular Component (CC) integral to plasma membrane 1 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect
Enzyme Commission (EC)Potassium-transporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Calcium-transporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Proton-exporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Phospholipid-translocating ATPase0Highly InformativeDirect
Enzyme Commission (EC)Copper-exporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Sodium/potassium-exchanging ATPase0Highly InformativeDirect
Enzyme Commission (EC)Cu(+) exporting ATPase0.0000000000001092Highly InformativeDirect
Enzyme Commission (EC)Cadmium-exporting ATPase0.000000000007156Highly InformativeDirect
Enzyme Commission (EC)Hydrogen/potassium-exchanging ATPase0.0000000004596Highly InformativeDirect
Enzyme Commission (EC)Zinc-exporting ATPase0.000000007355Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)muscle phenotype0.02541Moderately InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.0006129InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.002257Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.202Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.007528Moderately InformativeInherited
Worm Phenotype (WP)nicotine response variant0.009701InformativeInherited
Worm Phenotype (WP)lipid metabolism variant0.06673InformativeInherited
Worm Phenotype (WP)cell membrane morphology variant0.00000000006327Highly InformativeDirect
Worm Phenotype (WP)nicotine hypersensitive0.00000003225Highly InformativeDirect
Worm Phenotype (WP)lipid composition variant0.0000001933Highly InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)sporangium0.0001175Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0.002441Least InformativeInherited
Plant ANatomical entity (PAN)flower0.03196Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure0.04703Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.06103Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue0.0000005963InformativeDirect
Plant ANatomical entity (PAN)parenchyma cell0.000000003406Highly InformativeDirect
Plant ANatomical entity (PAN)anther0.0005621Highly InformativeDirect
Plant ANatomical entity (PAN)mesophyll1Highly InformativeInherited
Plant structure DEvelopment stage (PDE)pollen development stage0.0002813Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembrane movement of substances0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processIon transport0Moderately InformativeDirect
Biological processLipid transport0.000000000002879InformativeDirect
Biological processCalcium transport0Highly InformativeDirect
Biological processPotassium transport0Highly InformativeDirect
Biological processSodium transport0.00000000007274Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCell membrane0.0000000003266Moderately InformativeDirect
Cellular componentEndosome0.00005124Moderately InformativeDirect
Cellular componentSarcoplasmic reticulum0Highly InformativeDirect
Coding sequence diversityAlternative splicing0.0002295Least InformativeDirect
DiseaseDisease mutation0.00000002055Least InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionCopper0InformativeDirect
Molecular functionPotassium0InformativeDirect
Molecular functionSodium0InformativeDirect
Molecular functionCadmium0Highly InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationNitration0.00001529InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Calcium ATPase, transmembrane domain M domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Calcium ATPase, transmembrane domain M superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]