SUPERFAMILY 1.75 HMM library and genome assignments server

Calcium ATPase, transmembrane domain M superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   Calcium ATPase, transmembrane domain M [ 81666]
Superfamily:   Calcium ATPase, transmembrane domain M [ 81665]
Families:   Calcium ATPase, transmembrane domain M [ 81664]


Superfamily statistics
Genomes (3,045) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 27,635 95,033 2
Proteins 27,394 94,861 2


Functional annotation
General category coiled coil
Detailed category This is a complex coiled arrangement. The details of which will appear on this page shortly (some coiled coil details are being checked before they are included on the site). If you want to see examples of the states please click here here. If you require further details urgently please contact Owen Rackham

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)developmental process0.061931Least InformativeInherited
Biological Process (BP)response to stimulus0.11640.01788Least InformativeInherited
Biological Process (BP)multicellular organismal process0.024620.2831Least InformativeInherited
Biological Process (BP)regulation of multicellular organismal process0.000037520.0001914Moderately InformativeDirect
Biological Process (BP)organ development0.0070790.5084Moderately InformativeInherited
Biological Process (BP)regulation of system process0.015780InformativeInherited
Biological Process (BP)muscle system process0.0015070.1644InformativeInherited
Biological Process (BP)regulation of muscle system process0.00000003480.000000000000007248Highly InformativeDirect
Biological Process (BP)striated muscle contraction0.000000047820.000002599Highly InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle0.0020760.001135Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.32490Least InformativeInherited
Cellular Component (CC)endoplasmic reticulum0.00032280Moderately InformativeDirect
Cellular Component (CC)sarcoplasmic reticulum0.000031050.00000000000001745Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.0006836 Least Informative Direct
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of cellular process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) positive regulation of biological process 0.9888 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.6813 Least Informative Inherited
Biological Process (BP) developmental process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) multicellular organismal process 0.2831 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.01788 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.0001914 Moderately Informative Direct
Biological Process (BP) ion transport 0 Moderately Informative Direct
Biological Process (BP) regulation of biological quality 0 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.0000006897 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.0001972 Moderately Informative Direct
Biological Process (BP) response to oxygen-containing compound 0.9923 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 0.06166 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.7199 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 1 Moderately Informative Inherited
Biological Process (BP) organ development 0.5084 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.1931 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.001486 Moderately Informative Inherited
Biological Process (BP) cellular response to stress 0.9248 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.4174 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) single-organism organelle organization 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) nervous system development 0.5491 Moderately Informative Inherited
Biological Process (BP) cell differentiation 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) multi-organism process 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.4201 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.005949 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.07498 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.1183 Moderately Informative Inherited
Biological Process (BP) signal transduction 0.8551 Moderately Informative Inherited
Biological Process (BP) regulation of system process 0 Informative Direct
Biological Process (BP) lipid localization 0 Informative Direct
Biological Process (BP) cellular chemical homeostasis 0 Informative Direct
Biological Process (BP) ion transmembrane transport 0 Informative Direct
Biological Process (BP) metal ion transport 0.000000000382 Informative Direct
Biological Process (BP) nucleoside monophosphate metabolic process 0.000000001247 Informative Direct
Biological Process (BP) regulation of ion transport 0.000000001948 Informative Direct
Biological Process (BP) blood circulation 0.000000006944 Informative Direct
Biological Process (BP) purine ribonucleotide metabolic process 0.00000001831 Informative Direct
Biological Process (BP) purine ribonucleoside metabolic process 0.00000002196 Informative Direct
Biological Process (BP) organophosphate catabolic process 0.0000001169 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.0000001203 Informative Direct
Biological Process (BP) single-organism membrane organization 0.000000671 Informative Direct
Biological Process (BP) carbohydrate derivative catabolic process 0.0000007127 Informative Direct
Biological Process (BP) nucleoside triphosphate metabolic process 0.0000009242 Informative Direct
Biological Process (BP) response to inorganic substance 0.00002262 Informative Direct
Biological Process (BP) nucleobase-containing compound catabolic process 0.00003146 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0.000248 Informative Direct
Biological Process (BP) cation homeostasis 0.0003519 Informative Direct
Biological Process (BP) regulation of body fluid levels 0.0003893 Informative Direct
Biological Process (BP) monovalent inorganic cation transport 1 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.3562 Informative Inherited
Biological Process (BP) response to organic cyclic compound 0.3912 Informative Inherited
Biological Process (BP) response to lipid 0.71 Informative Inherited
Biological Process (BP) cell projection organization 1 Informative Inherited
Biological Process (BP) organ morphogenesis 0.2818 Informative Inherited
Biological Process (BP) epithelium development 0.1532 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.5723 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.005661 Informative Inherited
Biological Process (BP) embryonic organ development 0.009824 Informative Inherited
Biological Process (BP) single-organism intracellular transport 1 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) regulation of lipid metabolic process 0.02985 Informative Inherited
Biological Process (BP) cytoskeleton organization 1 Informative Inherited
Biological Process (BP) actin filament-based process 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.4125 Informative Inherited
Biological Process (BP) central nervous system development 0.01333 Informative Inherited
Biological Process (BP) intracellular signal transduction 0.6699 Informative Inherited
Biological Process (BP) biological adhesion 0.5018 Informative Inherited
Biological Process (BP) anion transport 1 Informative Inherited
Biological Process (BP) response to light stimulus 0.01045 Informative Inherited
Biological Process (BP) single-organism behavior 0.1511 Informative Inherited
Biological Process (BP) gland development 0.02613 Informative Inherited
Biological Process (BP) muscle system process 0.1644 Informative Inherited
Biological Process (BP) sensory organ development 0.0131 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.1508 Informative Inherited
Biological Process (BP) generation of neurons 0.3539 Informative Inherited
Biological Process (BP) neurological system process 0.6181 Informative Inherited
Biological Process (BP) synaptic transmission 0.2574 Informative Inherited
Biological Process (BP) regulation of muscle system process 0.000000000000007248 Highly Informative Direct
Biological Process (BP) striated muscle contraction 0.000002599 Highly Informative Direct
Biological Process (BP) response to transition metal nanoparticle 0.0000000000003216 Highly Informative Direct
Biological Process (BP) organophosphate ester transport 0.00000000005116 Highly Informative Direct
Biological Process (BP) secretion by tissue 0.000000001263 Highly Informative Direct
Biological Process (BP) negative regulation of hormone metabolic process 0.000000004055 Highly Informative Direct
Biological Process (BP) locomotory behavior 0.0000001782 Highly Informative Direct
Biological Process (BP) epidermis development 0.0000003246 Highly Informative Direct
Biological Process (BP) ER-nucleus signaling pathway 0.0000003568 Highly Informative Direct
Biological Process (BP) phenol-containing compound metabolic process 0.0000004381 Highly Informative Direct
Biological Process (BP) body fluid secretion 0.0000008428 Highly Informative Direct
Biological Process (BP) negative regulation of lipid biosynthetic process 0.000001402 Highly Informative Direct
Biological Process (BP) response to drug 0.000001948 Highly Informative Direct
Biological Process (BP) regulation of steroid biosynthetic process 0.000004414 Highly Informative Direct
Biological Process (BP) adult behavior 0.000005358 Highly Informative Direct
Biological Process (BP) nucleoside monophosphate catabolic process 0.00002978 Highly Informative Direct
Biological Process (BP) response to endoplasmic reticulum stress 0.0001834 Highly Informative Direct
Biological Process (BP) embryonic organ morphogenesis 0.0002931 Highly Informative Direct
Biological Process (BP) ear development 0.0005301 Highly Informative Direct
Biological Process (BP) cellular response to steroid hormone stimulus 0.0007618 Highly Informative Direct
Biological Process (BP) sodium ion transport 0.0008101 Highly Informative Direct
Biological Process (BP) transition metal ion homeostasis 0.9283 Highly Informative Inherited
Biological Process (BP) cellular calcium ion homeostasis 0.0181 Highly Informative Inherited
Biological Process (BP) maintenance of location 0.3487 Highly Informative Inherited
Biological Process (BP) sensory perception 0.962 Highly Informative Inherited
Biological Process (BP) calcium ion transport 0.002697 Highly Informative Inherited
Biological Process (BP) cell adhesion 0.3806 Highly Informative Inherited
Biological Process (BP) response to toxic substance 0.001548 Highly Informative Inherited
Biological Process (BP) learning or memory 0.001765 Highly Informative Inherited
Biological Process (BP) transition metal ion transport 0.505 Highly Informative Inherited
Biological Process (BP) purine ribonucleoside catabolic process 0.03932 Highly Informative Inherited
Biological Process (BP) purine ribonucleotide catabolic process 0.0562 Highly Informative Inherited
Biological Process (BP) ribonucleoside triphosphate catabolic process 0.2429 Highly Informative Inherited
Biological Process (BP) purine nucleoside triphosphate catabolic process 0.2846 Highly Informative Inherited
Biological Process (BP) retina development in camera-type eye 0.01689 Highly Informative Inherited
Biological Process (BP) post-embryonic development 0.5437 Highly Informative Inherited
Biological Process (BP) epithelial cell development 0.07432 Highly Informative Inherited
Biological Process (BP) cell morphogenesis involved in differentiation 0.09217 Highly Informative Inherited
Biological Process (BP) regulation of neurotransmitter levels 0.8039 Highly Informative Inherited
Biological Process (BP) neurotransmitter transport 1 Highly Informative Inherited
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) binding 0.311 Least Informative Inherited
Molecular Function (MF) transporter activity 0 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.000000000002171 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.00000000007557 Moderately Informative Direct
Molecular Function (MF) cation binding 0.00000003448 Moderately Informative Direct
Molecular Function (MF) anion binding 0.1136 Moderately Informative Inherited
Molecular Function (MF) active transmembrane transporter activity 0 Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) purine ribonucleoside binding 0 Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.000000000000003138 Informative Direct
Molecular Function (MF) nucleotide binding 0.00000000000006276 Informative Direct
Molecular Function (MF) metal ion transmembrane transporter activity 0.0000000000001343 Informative Direct
Molecular Function (MF) monovalent inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) ATPase activity, coupled to transmembrane movement of ions 0 Highly Informative Direct
Molecular Function (MF) ATP binding 0 Highly Informative Direct
Molecular Function (MF) calcium ion binding 0.000007139 Highly Informative Direct
Molecular Function (MF) copper ion binding 0.00002854 Highly Informative Direct
Molecular Function (MF) calcium ion transmembrane transporter activity 0.00003597 Highly Informative Direct
Molecular Function (MF) transition metal ion transmembrane transporter activity 0.0002785 Highly Informative Direct
Molecular Function (MF) protein domain specific binding 0.02365 Highly Informative Inherited
Molecular Function (MF) hydrogen ion transmembrane transporter activity 0.2726 Highly Informative Inherited
Molecular Function (MF) lipid transporter activity 0.02162 Highly Informative Inherited
Molecular Function (MF) sodium ion transmembrane transporter activity 0.06896 Highly Informative Inherited
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) protein complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.0346 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.001135 Least Informative Inherited
Cellular Component (CC) endoplasmic reticulum 0 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.0000004985 Moderately Informative Direct
Cellular Component (CC) plasma membrane part 0.000001071 Moderately Informative Direct
Cellular Component (CC) membrane region 0.0001297 Moderately Informative Direct
Cellular Component (CC) intrinsic component of membrane 0.0003083 Moderately Informative Direct
Cellular Component (CC) Golgi apparatus 0 Informative Direct
Cellular Component (CC) vacuolar part 0.000001042 Informative Direct
Cellular Component (CC) transporter complex 0.000006539 Informative Direct
Cellular Component (CC) integral component of membrane 0.00002243 Informative Direct
Cellular Component (CC) endoplasmic reticulum membrane 0.0003214 Informative Direct
Cellular Component (CC) contractile fiber part 0.001304 Informative Inherited
Cellular Component (CC) intrinsic component of plasma membrane 0.7026 Informative Inherited
Cellular Component (CC) sarcoplasmic reticulum 0.00000000000001745 Highly Informative Direct
Cellular Component (CC) trans-Golgi network 0.0000000000001325 Highly Informative Direct
Cellular Component (CC) sarcomere 0.000004956 Highly Informative Direct
Cellular Component (CC) sarcolemma 0.000008674 Highly Informative Direct
Cellular Component (CC) perinuclear region of cytoplasm 0.0007376 Highly Informative Direct
Cellular Component (CC) integral component of plasma membrane 0.4297 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect
Enzyme Commission (EC)Potassium-transporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Calcium-transporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Proton-exporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Phospholipid-translocating ATPase0Highly InformativeDirect
Enzyme Commission (EC)Copper-exporting ATPase0Highly InformativeDirect
Enzyme Commission (EC)Sodium/potassium-exchanging ATPase0Highly InformativeDirect
Enzyme Commission (EC)Cu(+) exporting ATPase0.0000000000001092Highly InformativeDirect
Enzyme Commission (EC)Cadmium-exporting ATPase0.000000000007156Highly InformativeDirect
Enzyme Commission (EC)Hydrogen/potassium-exchanging ATPase0.0000000004596Highly InformativeDirect
Enzyme Commission (EC)Zinc-exporting ATPase0.000000007355Highly InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)muscle phenotype0.02663Moderately InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.0006283InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.002257Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.202Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.007528Moderately InformativeInherited
Worm Phenotype (WP)nicotine response variant0.009701InformativeInherited
Worm Phenotype (WP)lipid metabolism variant0.06673InformativeInherited
Worm Phenotype (WP)cell membrane morphology variant0.00000000006327Highly InformativeDirect
Worm Phenotype (WP)nicotine hypersensitive0.00000003225Highly InformativeDirect
Worm Phenotype (WP)lipid composition variant0.0000001933Highly InformativeDirect

Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)sporangium0.0001175Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0.002441Least InformativeInherited
Plant ANatomical entity (PAN)flower0.03196Least InformativeInherited
Plant ANatomical entity (PAN)collective phyllome structure0.04703Least InformativeInherited
Plant ANatomical entity (PAN)whole plant0.06103Least InformativeInherited
Plant ANatomical entity (PAN)portion of ground tissue0.0000005963InformativeDirect
Plant ANatomical entity (PAN)parenchyma cell0.000000003406Highly InformativeDirect
Plant ANatomical entity (PAN)anther0.0005621Highly InformativeDirect
Plant ANatomical entity (PAN)mesophyll1Highly InformativeInherited
Plant structure DEvelopment stage (PDE)pollen development stage0.0002813Moderately InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembrane movement of substances0Highly InformativeDirect

Document: EC annotation of SCOP domains

DrugBank ATC (DB)

(show details)
DB termFDR (all)SDDB levelAnnotation (direct or inherited)
Drugbank ATC_code (DB)alimentary tract and metabolism0Least InformativeDirect
Drugbank ATC_code (DB)drugs for acid related disorders0InformativeDirect

Document: DB annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processIon transport0Moderately InformativeDirect
Biological processLipid transport0.000000000002802InformativeDirect
Biological processCalcium transport0Highly InformativeDirect
Biological processPotassium transport0Highly InformativeDirect
Biological processSodium transport0.00000000006942Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentEndoplasmic reticulum0Moderately InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCell membrane0.0000000004304Moderately InformativeDirect
Cellular componentEndosome0.00005507Moderately InformativeDirect
Cellular componentSarcoplasmic reticulum0Highly InformativeDirect
Coding sequence diversityAlternative splicing0.0002673Least InformativeDirect
DiseaseDisease mutation0.00000002281Least InformativeDirect
DomainTransmembrane0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionATP-binding0Moderately InformativeDirect
Molecular functionCalcium0Moderately InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionCalmodulin-binding0InformativeDirect
Molecular functionCopper0InformativeDirect
Molecular functionPotassium0InformativeDirect
Molecular functionSodium0InformativeDirect
Molecular functionCadmium0Highly InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationNitration0.00001512InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Calcium ATPase, transmembrane domain M domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Calcium ATPase, transmembrane domain M superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · DrugBank ATC (DB) · UniProtKB KeyWords (KW) · Internal database links ]