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Obg GTP-binding protein N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Obg-fold [ 82050]
Superfamily:   Obg GTP-binding protein N-terminal domain [ 82051]
Families:   Obg GTP-binding protein N-terminal domain [ 82052]


Superfamily statistics
Genomes (3,051) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,529 17,923 2
Proteins 3,511 17,827 2


Functional annotation
General category General
Detailed category Small molecule binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Molecular Function (MF) binding 0.4307 Least Informative Inherited
Molecular Function (MF) hydrolase activity 0.002877 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0000006091 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.000005801 Moderately Informative Direct
Molecular Function (MF) carbohydrate derivative binding 0.0000006885 Moderately Informative Direct
Molecular Function (MF) anion binding 0.02264 Moderately Informative Inherited
Molecular Function (MF) purine nucleotide binding 0.00000004695 Informative Direct
Molecular Function (MF) ribonucleotide binding 0.00000005641 Informative Direct
Molecular Function (MF) purine ribonucleoside triphosphate binding 0.00000001578 Informative Direct
Molecular Function (MF) purine nucleoside binding 0.000000000006818 Highly Informative Direct
Cellular Component (CC) intracellular organelle part 0.7521 Least Informative Inherited
Cellular Component (CC) membrane 0.4305 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.3147 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.05589 Least Informative Inherited
Cellular Component (CC) organelle inner membrane 0.000002222 Moderately Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR006169 SSF82051 Protein matches
Abstract

Several proteins have recently been shown to contain the 5 structural motifs characteristic of GTP-binding proteins [PubMed1449490]. These include murine DRG protein; GTP1 protein from Schizosaccharomyces pombe; OBG protein from Bacillus subtilis; and several others. Although the proteins contain GTP-binding motifs and are similar to each other, they do not share sequence similarity to other GTP-binding proteins, and have thus been classed as a novel group, the GTP1/OBG family. As yet, the functions of these proteins is uncertain, but they have been shown to be important in development and normal cell metabolism [PubMed8462872, PubMed2537815].


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Obg GTP-binding protein N-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Obg GTP-binding protein N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]