|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
regulation of proteasomal protein catabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle |
0 |
1.377 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of proteasomal ubiquitin-dependent protein catabolic process |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of microtubule-based process |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cell cycle checkpoint |
0 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of microtubule cytoskeleton organization |
0 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle |
0 |
1.444 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization to chromosome |
1.158e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular catabolic process |
1.896e-14 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cellular component organization |
2.258e-14 |
0.6819 |
-- |
DIRECT |
| Biological Process (BP) |
G2 DNA damage checkpoint |
2.258e-14 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
phosphorylation |
3.329e-14 |
1.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of catabolic process |
2.148e-13 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
4.763e-13 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of programmed cell death |
5.45e-12 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of ubiquitin-protein ligase activity |
6.822e-12 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of ligase activity |
1.117e-11 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of ubiquitin-protein ligase activity |
6.129e-11 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
2.616e-10 |
0.4486 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of protein ubiquitination |
3.799e-10 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catabolic process |
4.529e-10 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
1.687e-09 |
0.3316 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of programmed cell death |
5.417e-09 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
phosphorus metabolic process |
5.693e-09 |
0.8013 |
-- |
DIRECT |
| Biological Process (BP) |
protein modification process |
6.227e-09 |
0.9066 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
2.172e-08 |
0.4202 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule modification |
2.735e-08 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
placenta development |
2.837e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell cycle process |
5.057e-08 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
1.128e-07 |
0.1415 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein metabolic process |
3.721e-07 |
0.6778 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular protein metabolic process |
3.253e-06 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular protein metabolic process |
3.263e-06 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex subunit organization |
3.368e-06 |
1.194 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of biological process |
4.126e-06 |
0.8182 |
-- |
DIRECT |
| Biological Process (BP) |
in utero embryonic development |
7.931e-06 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
1.913e-05 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of transcription from RNA polymerase II promoter |
6.064e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of nucleobase-containing compound metabolic process |
6.807e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization |
6.972e-05 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
spindle organization |
0.0001103 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of macromolecule biosynthetic process |
0.000126 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of transcription, DNA-dependent |
0.0001368 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
0.0001575 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular biosynthetic process |
0.0001577 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
organelle fission |
0.0003842 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle |
0.0004655 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell death |
0.0004976 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
embryo development |
0.0007385 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
0.0008671 |
0.4634 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle phase transition |
0.08764 |
2.222 |
-- |
INHERITED FROM: positive regulation of metaphase/anaphase transition of cell cycle || positive regulation of mitotic metaphase/anaphase transition || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
regulation of primary metabolic process |
0.0106 |
0.7852 |
-- |
INHERITED FROM: regulation of proteasomal protein catabolic process || regulation of proteolysis || positive regulation of protein ubiquitination || regulation of protein metabolic process || regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of protein catabolic process || regulation of protein ubiquitination || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of protein metabolic process || regulation of transcription from RNA polymerase II promoter || positive regulation of proteasomal protein catabolic process || negative regulation of nucleobase-containing compound metabolic process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of transcription, DNA-dependent || positive regulation of proteolysis || activation of mitotic anaphase-promoting complex activity || regulation of cellular protein metabolic process || negative regulation of transcription from RNA polymerase II promoter || positive regulation of ubiquitin-protein ligase activity || regulation of protein catabolic process || negative regulation of RNA metabolic process || positive regulation of cellular protein metabolic process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0.009602 |
0.7959 |
-- |
INHERITED FROM: regulation of proteasomal protein catabolic process || regulation of proteolysis || positive regulation of protein ubiquitination || regulation of protein metabolic process || regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of protein catabolic process || regulation of protein ubiquitination || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of protein metabolic process || regulation of transcription from RNA polymerase II promoter || positive regulation of proteasomal protein catabolic process || negative regulation of gene expression || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of transcription, DNA-dependent || positive regulation of proteolysis || activation of mitotic anaphase-promoting complex activity || negative regulation of macromolecule biosynthetic process || regulation of cellular protein metabolic process || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter || positive regulation of macromolecule metabolic process || positive regulation of ubiquitin-protein ligase activity || regulation of protein catabolic process || negative regulation of RNA metabolic process || positive regulation of cellular protein metabolic process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
cellular developmental process |
0.446 |
0.9666 |
-- |
INHERITED FROM: trophoblast giant cell differentiation || cell differentiation involved in embryonic placenta development |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
0.08596 |
1.027 |
-- |
INHERITED FROM: negative regulation of RNA metabolic process || regulation of transcription from RNA polymerase II promoter || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
positive regulation of cytoskeleton organization |
0.04304 |
2.699 |
-- |
INHERITED FROM: positive regulation of centriole replication |
| Biological Process (BP) |
negative regulation of biological process |
0.08923 |
0.8665 |
-- |
INHERITED FROM: negative regulation of nucleobase-containing compound metabolic process || negative regulation of cell cycle process || G2 DNA damage checkpoint || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter || DNA damage checkpoint || negative regulation of apoptotic process || negative regulation of cellular biosynthetic process || negative regulation of biosynthetic process || negative regulation of programmed cell death || negative regulation of cell death || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || cell cycle checkpoint || negative regulation of macromolecule biosynthetic process || negative regulation of RNA metabolic process || negative regulation of nitrogen compound metabolic process |
| Biological Process (BP) |
positive regulation of mitotic cell cycle phase transition |
0.02485 |
2.222 |
-- |
INHERITED FROM: positive regulation of mitotic metaphase/anaphase transition || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
regulation of mitotic metaphase/anaphase transition |
0.02762 |
2.398 |
-- |
INHERITED FROM: positive regulation of mitotic metaphase/anaphase transition || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
organic substance metabolic process |
0.04521 |
0.2676 |
-- |
INHERITED FROM: macromolecule modification || cellular protein modification process || cellular protein metabolic process || protein modification process || protein metabolic process || macromolecule metabolic process || protein phosphorylation || cellular macromolecule metabolic process |
| Biological Process (BP) |
metabolic process |
0.2307 |
0.2411 |
-- |
INHERITED FROM: macromolecule modification || cellular protein modification process || cellular protein metabolic process || protein modification process || protein metabolic process || macromolecule metabolic process || protein phosphorylation || phosphorylation || cellular macromolecule metabolic process || phosphorus metabolic process || phosphate-containing compound metabolic process |
| Biological Process (BP) |
positive regulation of molecular function |
0.001241 |
1.222 |
-- |
INHERITED FROM: positive regulation of catalytic activity || activation of anaphase-promoting complex activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || activation of mitotic anaphase-promoting complex activity || positive regulation of ubiquitin-protein ligase activity || positive regulation of ligase activity |
| Biological Process (BP) |
regulation of catalytic activity |
0.02818 |
1.155 |
-- |
INHERITED FROM: positive regulation of catalytic activity || positive regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ubiquitin-protein ligase activity || regulation of ligase activity || activation of anaphase-promoting complex activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || activation of mitotic anaphase-promoting complex activity || positive regulation of ligase activity |
| Biological Process (BP) |
cellular macromolecule localization |
0.005757 |
1.319 |
-- |
INHERITED FROM: protein localization to organelle || protein localization to chromosome || protein localization to chromatin |
| Biological Process (BP) |
cellular protein localization |
0.184 |
1.337 |
-- |
INHERITED FROM: protein localization to organelle || protein localization to chromosome || protein localization to chromatin |
| Biological Process (BP) |
cellular response to stimulus |
0.141 |
0.7645 |
-- |
INHERITED FROM: G2 DNA damage checkpoint || DNA damage checkpoint || cellular response to stress |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0.3548 |
1.208 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of cellular catabolic process || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of proteasomal protein catabolic process || positive regulation of cellular protein metabolic process || positive regulation of proteolysis || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
regulation of protein modification process |
1 |
1.377 |
-- |
INHERITED FROM: positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of protein ubiquitination || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
0.08648 |
1.009 |
-- |
INHERITED FROM: negative regulation of cellular biosynthetic process || regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of cytoskeleton organization |
0.01321 |
1.854 |
-- |
INHERITED FROM: regulation of centrosome duplication || regulation of microtubule cytoskeleton organization || regulation of centrosome cycle || positive regulation of centrosome cycle || regulation of centriole replication || positive regulation of centriole replication |
| Biological Process (BP) |
negative regulation of macromolecule metabolic process |
0.00163 |
1.301 |
-- |
INHERITED FROM: negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || negative regulation of RNA metabolic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
single-multicellular organism process |
1 |
0.6383 |
-- |
INHERITED FROM: embryo development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || cell differentiation involved in embryonic placenta development || placenta development || chordate embryonic development || in utero embryonic development |
| Biological Process (BP) |
anatomical structure development |
0.06378 |
0.7212 |
-- |
INHERITED FROM: embryo development || placenta development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || chordate embryonic development || cell differentiation involved in embryonic placenta development || in utero embryonic development |
| Biological Process (BP) |
multicellular organismal development |
0.8345 |
0.7496 |
-- |
INHERITED FROM: embryo development || placenta development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || chordate embryonic development || cell differentiation involved in embryonic placenta development || in utero embryonic development |
| Biological Process (BP) |
biological_process |
0.01636 |
0 |
-- |
INHERITED FROM: centrosome cycle || positive regulation of ligase activity || cellular component organization or biogenesis || negative regulation of cell cycle process || G2 DNA damage checkpoint || positive regulation of macromolecule metabolic process || regulation of cell cycle process || negative regulation of apoptotic process || protein modification process || trophoblast giant cell differentiation || activation of anaphase-promoting complex activity || regulation of microtubule cytoskeleton organization || protein localization to organelle || regulation of cellular catabolic process || cell cycle phase transition || cell division || regulation of ligase activity || protein phosphorylation || regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of ubiquitin-protein ligase activity || regulation of proteasomal protein catabolic process || positive regulation of centrosome cycle || regulation of protein ubiquitination || phosphate-containing compound metabolic process || negative regulation of transcription, DNA-dependent || positive regulation of centriole replication || negative regulation of macromolecule biosynthetic process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || macromolecule modification || protein localization to chromosome || embryo development || centrosome organization || positive regulation of organelle organization || cellular protein modification process || DNA damage checkpoint || positive regulation of cellular process || regulation of microtubule-based process || positive regulation of cell cycle || protein metabolic process || regulation of catabolic process || negative regulation of gene expression || regulation of cellular protein metabolic process || spindle organization || cell differentiation involved in embryonic placenta development || positive regulation of metaphase/anaphase transition of cell cycle || negative regulation of nitrogen compound metabolic process || regulation of cellular process || regulation of biological process || positive regulation of proteolysis || cellular macromolecule metabolic process || negative regulation of cellular macromolecule biosynthetic process || protein complex subunit organization || positive regulation of cellular protein metabolic process || regulation of centriole replication || regulation of ubiquitin-protein ligase activity || negative regulation of biosynthetic process || microtubule-based process || regulation of transcription from RNA polymerase II promoter || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || in utero embryonic development || protein localization || centrosome duplication || mitotic cell cycle || protein localization to chromatin || regulation of cell death || cellular protein metabolic process || positive regulation of cellular component organization || chromosome segregation || negative regulation of cellular biosynthetic process || regulation of cellular component organization || positive regulation of cell cycle process || cellular component organization || positive regulation of protein ubiquitination || phosphorylation || positive regulation of protein metabolic process || single-organism process || regulation of centrosome cycle || negative regulation of transcription from RNA polymerase II promoter || biological regulation || centriole replication || regulation of organelle organization || placenta development || phosphorus metabolic process || cellular component disassembly || regulation of protein metabolic process || regulation of centrosome duplication || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || negative regulation of cell death || activation of mitotic anaphase-promoting complex activity || regulation of programmed cell death || organelle organization || regulation of protein catabolic process || microtubule cytoskeleton organization || cellular process || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || cell cycle || regulation of cell cycle || positive regulation of catabolic process || embryonic organ development || single-organism cellular process || embryonic placenta development || positive regulation of proteasomal protein catabolic process || cell cycle process || macromolecule metabolic process || positive regulation of catalytic activity || cellular response to stress || nuclear division || positive regulation of biological process || regulation of proteolysis || positive regulation of protein catabolic process || positive regulation of cellular catabolic process || regulation of apoptotic process || organelle fission || chordate embryonic development || negative regulation of programmed cell death || cytoskeleton organization || cell cycle checkpoint || macromolecule localization || positive regulation of mitotic metaphase/anaphase transition || microtubule organizing center organization |
| Biological Process (BP) |
regulation of metaphase/anaphase transition of cell cycle |
0.04118 |
2.398 |
-- |
INHERITED FROM: activation of mitotic anaphase-promoting complex activity || positive regulation of metaphase/anaphase transition of cell cycle || positive regulation of mitotic metaphase/anaphase transition |
| Biological Process (BP) |
positive regulation of protein modification process |
0.5923 |
1.585 |
-- |
INHERITED FROM: activation of mitotic anaphase-promoting complex activity || positive regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || positive regulation of protein ubiquitination |
| Biological Process (BP) |
regulation of mitotic cell cycle phase transition |
0.02183 |
1.699 |
-- |
INHERITED FROM: activation of mitotic anaphase-promoting complex activity || positive regulation of mitotic metaphase/anaphase transition |
| Biological Process (BP) |
regulation of nuclear division |
0.09452 |
2.398 |
-- |
INHERITED FROM: activation of mitotic anaphase-promoting complex activity || positive regulation of mitotic metaphase/anaphase transition |
| Biological Process (BP) |
regulation of mitosis |
0.3096 |
2.398 |
-- |
INHERITED FROM: activation of mitotic anaphase-promoting complex activity || positive regulation of mitotic metaphase/anaphase transition |
| Biological Process (BP) |
primary metabolic process |
0.0211 |
0.2976 |
-- |
INHERITED FROM: protein phosphorylation || cellular protein modification process || cellular protein metabolic process || protein modification process || protein metabolic process |
| Biological Process (BP) |
cellular metabolic process |
1 |
0.2708 |
-- |
INHERITED FROM: cellular protein modification process || cellular protein metabolic process || protein phosphorylation || phosphorylation || cellular macromolecule metabolic process || phosphorus metabolic process || phosphate-containing compound metabolic process |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
0.002599 |
1.119 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of RNA metabolic process |
0.02236 |
1.131 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of RNA metabolic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
0.05233 |
1.066 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0.001332 |
1.237 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
0.001384 |
1.167 |
-- |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.1254 |
1.469 |
-- |
INHERITED FROM: embryonic placenta development || cell differentiation involved in embryonic placenta development || in utero embryonic development || trophoblast giant cell differentiation || chordate embryonic development |
| Biological Process (BP) |
system development |
0.414 |
0.8069 |
-- |
INHERITED FROM: placenta development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || cell differentiation involved in embryonic placenta development |
| Biological Process (BP) |
response to stress |
0.001812 |
0.8125 |
-- |
INHERITED FROM: DNA damage checkpoint || cellular response to stress || G2 DNA damage checkpoint |
| Biological Process (BP) |
DNA integrity checkpoint |
0.8499 |
2.097 |
-- |
INHERITED FROM: DNA damage checkpoint || G2 DNA damage checkpoint |
| Biological Process (BP) |
regulation of cell cycle phase transition |
0.7921 |
1.62 |
-- |
INHERITED FROM: cell cycle checkpoint || activation of mitotic anaphase-promoting complex activity || positive regulation of metaphase/anaphase transition of cell cycle || DNA damage checkpoint || G2 DNA damage checkpoint || positive regulation of mitotic metaphase/anaphase transition |
| Biological Process (BP) |
negative regulation of cell cycle phase transition |
0.0108 |
1.854 |
-- |
INHERITED FROM: cell cycle checkpoint || DNA damage checkpoint || G2 DNA damage checkpoint |
| Biological Process (BP) |
single-organism cellular process |
3.176e-13 |
0.3915 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular component organization or biogenesis |
1.031e-12 |
0.6536 |
Least Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular process |
1.883e-11 |
0.5317 |
Least Informative |
DIRECT |
| Biological Process (BP) |
protein metabolic process |
2.459e-06 |
0.6383 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule metabolic process |
0.0002593 |
0.4976 |
Least Informative |
DIRECT |
| Biological Process (BP) |
localization |
0.3044 |
0.6946 |
Least Informative |
INHERITED FROM: protein localization to chromosome || protein localization to chromatin || protein localization to organelle || macromolecule localization || protein localization |
| Biological Process (BP) |
response to stimulus |
0.01726 |
0.5498 |
Least Informative |
INHERITED FROM: G2 DNA damage checkpoint || DNA damage checkpoint || cellular response to stress |
| Biological Process (BP) |
regulation of metabolic process |
1 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of proteolysis || positive regulation of protein ubiquitination || regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of protein catabolic process || positive regulation of cellular catabolic process || positive regulation of protein metabolic process || positive regulation of ligase activity || negative regulation of nucleobase-containing compound metabolic process || positive regulation of proteolysis || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter || positive regulation of macromolecule metabolic process || positive regulation of ubiquitin-protein ligase activity || positive regulation of catabolic process || positive regulation of cellular protein metabolic process || regulation of proteasomal protein catabolic process || negative regulation of cellular biosynthetic process || regulation of protein metabolic process || regulation of ubiquitin-protein ligase activity || negative regulation of biosynthetic process || activation of anaphase-promoting complex activity || regulation of protein ubiquitination || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of transcription from RNA polymerase II promoter || positive regulation of proteasomal protein catabolic process || regulation of catabolic process || negative regulation of gene expression || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of transcription, DNA-dependent || activation of mitotic anaphase-promoting complex activity || negative regulation of macromolecule biosynthetic process || regulation of cellular protein metabolic process || regulation of cellular catabolic process || regulation of protein catabolic process || negative regulation of RNA metabolic process || positive regulation of catalytic activity || regulation of ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of nitrogen compound metabolic process |
| Biological Process (BP) |
multicellular organismal process |
0.06797 |
0.6091 |
Least Informative |
INHERITED FROM: embryo development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || cell differentiation involved in embryonic placenta development || placenta development || chordate embryonic development || in utero embryonic development |
| Biological Process (BP) |
developmental process |
0.2236 |
0.6904 |
Least Informative |
INHERITED FROM: embryo development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || cell differentiation involved in embryonic placenta development || placenta development || chordate embryonic development || in utero embryonic development |
| Biological Process (BP) |
regulation of cellular component organization |
4.032e-12 |
1.18 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
organelle organization |
2.6e-11 |
0.8996 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
phosphate-containing compound metabolic process |
3.578e-09 |
0.8182 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular protein modification process |
6.227e-09 |
0.9066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular process |
1.548e-06 |
0.9066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular response to stress |
2.041e-06 |
1.086 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein metabolic process |
1.096e-05 |
1.119 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
macromolecule localization |
0.0002823 |
1.046 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
macromolecular complex subunit organization |
0.2794 |
1.131 |
Moderately Informative |
INHERITED FROM: protein complex subunit organization || spindle organization |
| Biological Process (BP) |
cell differentiation |
0.001285 |
1.009 |
Moderately Informative |
INHERITED FROM: trophoblast giant cell differentiation || cell differentiation involved in embryonic placenta development |
| Biological Process (BP) |
regulation of molecular function |
0.3652 |
1.056 |
Moderately Informative |
INHERITED FROM: positive regulation of ubiquitin-protein ligase activity || regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of ligase activity || positive regulation of catalytic activity || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || regulation of ligase activity || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
cellular localization |
0.1797 |
1.027 |
Moderately Informative |
INHERITED FROM: protein localization to organelle || protein localization to chromosome || protein localization to chromatin |
| Biological Process (BP) |
regulation of cellular metabolic process |
1 |
0.7905 |
Moderately Informative |
INHERITED FROM: positive regulation of protein ubiquitination || regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of cellular catabolic process || negative regulation of nucleobase-containing compound metabolic process || positive regulation of proteolysis || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter || positive regulation of ubiquitin-protein ligase activity || positive regulation of cellular protein metabolic process || regulation of proteasomal protein catabolic process || negative regulation of cellular biosynthetic process || regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || regulation of protein ubiquitination || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || regulation of transcription from RNA polymerase II promoter || positive regulation of proteasomal protein catabolic process || regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || negative regulation of transcription, DNA-dependent || activation of mitotic anaphase-promoting complex activity || regulation of cellular protein metabolic process || regulation of cellular catabolic process || negative regulation of RNA metabolic process || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
| Biological Process (BP) |
negative regulation of cellular process |
0.06172 |
0.9355 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of programmed cell death || negative regulation of cell death || negative regulation of nucleobase-containing compound metabolic process || negative regulation of cell cycle process || negative regulation of transcription, DNA-dependent || G2 DNA damage checkpoint || cell cycle checkpoint || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter || DNA damage checkpoint || negative regulation of RNA metabolic process || negative regulation of apoptotic process |
| Biological Process (BP) |
negative regulation of metabolic process |
0.0214 |
1.222 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of biosynthetic process || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of nitrogen compound metabolic process || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of biosynthetic process |
0.02817 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of biosynthetic process || regulation of transcription from RNA polymerase II promoter || negative regulation of transcription, DNA-dependent || negative regulation of macromolecule biosynthetic process || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
positive regulation of metabolic process |
0.2407 |
1.167 |
Moderately Informative |
INHERITED FROM: positive regulation of macromolecule metabolic process || positive regulation of protein ubiquitination || positive regulation of ubiquitin-protein ligase activity || activation of anaphase-promoting complex activity || positive regulation of protein catabolic process || positive regulation of cellular catabolic process || positive regulation of catabolic process || positive regulation of proteasomal ubiquitin-dependent protein catabolic process || positive regulation of protein metabolic process || positive regulation of proteasomal protein catabolic process || positive regulation of cellular protein metabolic process || positive regulation of proteolysis || positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle || activation of mitotic anaphase-promoting complex activity |
| Biological Process (BP) |
single-organism developmental process |
1 |
0.7645 |
Moderately Informative |
INHERITED FROM: embryo development || placenta development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || chordate embryonic development || cell differentiation involved in embryonic placenta development || in utero embryonic development |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
0.03936 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || negative regulation of transcription from RNA polymerase II promoter || negative regulation of RNA metabolic process || negative regulation of nitrogen compound metabolic process |
| Biological Process (BP) |
regulation of gene expression |
0.1829 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of transcription from RNA polymerase II promoter || negative regulation of gene expression || negative regulation of transcription, DNA-dependent || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
organ development |
0.4857 |
0.9355 |
Moderately Informative |
INHERITED FROM: placenta development || trophoblast giant cell differentiation || embryonic organ development || embryonic placenta development || cell differentiation involved in embryonic placenta development |
| Biological Process (BP) |
cell cycle process |
0 |
1.377 |
Informative |
DIRECT |
| Biological Process (BP) |
microtubule-based process |
0 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
protein phosphorylation |
4.008e-15 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular catabolic process |
4.785e-10 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic process |
1.829e-09 |
1.337 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cellular component organization |
1.88e-09 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell death |
8.253e-07 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
protein localization to organelle |
1.157e-06 |
1.523 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular component disassembly |
1.845e-06 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
cytoskeleton organization |
6.463e-06 |
1.301 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of organelle organization |
6.8e-06 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of transcription from RNA polymerase II promoter |
6.992e-06 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of protein metabolic process |
9.743e-06 |
1.469 |
Informative |
DIRECT |
| Biological Process (BP) |
embryonic organ development |
1.202e-05 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle process |
1.775e-05 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of nitrogen compound metabolic process |
4.817e-05 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of biosynthetic process |
0.0001214 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
chordate embryonic development |
0.0001282 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.0004365 |
1.337 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular metabolic process |
0.01917 |
1.301 |
Informative |
INHERITED FROM: negative regulation of cellular biosynthetic process || negative regulation of RNA metabolic process || negative regulation of nucleobase-containing compound metabolic process || negative regulation of transcription, DNA-dependent || negative regulation of cellular macromolecule biosynthetic process || negative regulation of transcription from RNA polymerase II promoter |
| Biological Process (BP) |
regulation of mitotic cell cycle |
0.7036 |
1.658 |
Informative |
INHERITED FROM: activation of mitotic anaphase-promoting complex activity || positive regulation of mitotic metaphase/anaphase transition |
| Biological Process (BP) |
response to DNA damage stimulus |
0.002078 |
1.495 |
Informative |
INHERITED FROM: DNA damage checkpoint || G2 DNA damage checkpoint |
| Biological Process (BP) |
regulation of protein catabolic process |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
microtubule cytoskeleton organization |
0 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of proteolysis |
5.966e-15 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of cell cycle process |
7.835e-15 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
nuclear division |
8.675e-13 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of apoptotic process |
2.106e-12 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of ligase activity |
8.575e-11 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
embryonic placenta development |
2.816e-09 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein ubiquitination |
8.959e-09 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell division |
4.337e-07 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
chromosome segregation |
1.021e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of RNA metabolic process |
7.768e-05 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
cell cycle phase transition |
8.283e-05 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of gene expression |
9.122e-05 |
1.796 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
DNA damage checkpoint |
0.000187 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular macromolecule biosynthetic process |
0.0002698 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of organelle organization |
0.0003025 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mitotic cell cycle |
0.0005538 |
1.854 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
catalytic activity |
1.425e-09 |
0.2686 |
-- |
DIRECT |
| Molecular Function (MF) |
microtubule binding |
4.943e-08 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
0.136 |
0 |
-- |
INHERITED FROM: microtubule binding || transferase activity, transferring phosphorus-containing groups || transferase activity || catalytic activity || tubulin binding || kinase activity |
| Molecular Function (MF) |
transferase activity |
0 |
0.7491 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
binding |
0.116 |
0.3952 |
Least Informative |
INHERITED FROM: microtubule binding || tubulin binding |
| Molecular Function (MF) |
transferase activity, transferring phosphorus-containing groups |
0 |
1.134 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
protein binding |
0.002168 |
0.77 |
Moderately Informative |
INHERITED FROM: tubulin binding || microtubule binding |
| Molecular Function (MF) |
kinase activity |
0 |
1.474 |
Informative |
DIRECT |
| Molecular Function (MF) |
cytoskeletal protein binding |
0.001262 |
1.423 |
Informative |
INHERITED FROM: microtubule binding || tubulin binding |
| Molecular Function (MF) |
tubulin binding |
1.776e-07 |
1.98 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
centriole |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoskeletal part |
0 |
1.127 |
-- |
DIRECT |
| Cellular Component (CC) |
microtubule organizing center part |
0 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
centrosome |
0 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
non-membrane-bounded organelle |
3.129e-15 |
0.6225 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
4.921e-13 |
0.3713 |
-- |
DIRECT |
| Cellular Component (CC) |
chromosome, centromeric region |
2.412e-12 |
2.064 |
-- |
DIRECT |
| Cellular Component (CC) |
nucleus |
7.825e-11 |
0.7857 |
-- |
DIRECT |
| Cellular Component (CC) |
spindle midzone |
4.064e-09 |
2.542 |
-- |
DIRECT |
| Cellular Component (CC) |
membrane-enclosed lumen |
1.488e-06 |
0.9395 |
-- |
DIRECT |
| Cellular Component (CC) |
spindle pole |
2.115e-06 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
4.979e-06 |
0.1836 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
0.5031 |
0.2515 |
-- |
INHERITED FROM: microtubule organizing center part || centriole |
| Cellular Component (CC) |
cellular_component |
0.001591 |
0 |
-- |
INHERITED FROM: midbody || chromosome, centromeric region || microtubule organizing center part || cytoskeleton || centrosome || spindle || organelle part || centriole || protein complex || microtubule cytoskeleton || non-membrane-bounded organelle || microtubule organizing center || intracellular organelle part || kinetochore || cytoskeletal part || membrane-enclosed lumen || spindle pole || intracellular non-membrane-bounded organelle || organelle || spindle midzone || nucleus |
| Cellular Component (CC) |
cell part |
0.002327 |
0.08068 |
-- |
INHERITED FROM: midbody || chromosome, centromeric region || microtubule organizing center part || cytoskeleton || centrosome || spindle || centriole || microtubule cytoskeleton || microtubule organizing center || intracellular organelle part || kinetochore || cytoskeletal part || spindle pole || intracellular non-membrane-bounded organelle || spindle midzone || nucleus |
| Cellular Component (CC) |
cell |
0.002346 |
0.08068 |
-- |
INHERITED FROM: midbody || chromosome, centromeric region || microtubule organizing center part || cytoskeleton || centrosome || spindle || centriole || microtubule cytoskeleton || microtubule organizing center || intracellular organelle part || kinetochore || cytoskeletal part || spindle pole || intracellular non-membrane-bounded organelle || spindle midzone || nucleus |
| Cellular Component (CC) |
intracellular organelle |
0.004327 |
0.1875 |
-- |
INHERITED FROM: microtubule cytoskeleton || chromosome, centromeric region || microtubule organizing center part || cytoskeleton || microtubule organizing center || intracellular organelle part || kinetochore || centrosome || spindle || cytoskeletal part || spindle pole || intracellular non-membrane-bounded organelle || centriole || spindle midzone || nucleus |
| Cellular Component (CC) |
intracellular part |
0.01063 |
0.1266 |
-- |
INHERITED FROM: microtubule cytoskeleton || chromosome, centromeric region || microtubule organizing center part || cytoskeleton || microtubule organizing center || intracellular organelle part || kinetochore || centrosome || spindle || cytoskeletal part || spindle pole || intracellular non-membrane-bounded organelle || centriole || spindle midzone || nucleus |
| Cellular Component (CC) |
intracellular |
0.01258 |
0.1266 |
-- |
INHERITED FROM: microtubule cytoskeleton || chromosome, centromeric region || microtubule organizing center part || cytoskeleton || microtubule organizing center || intracellular organelle part || kinetochore || centrosome || spindle || cytoskeletal part || spindle pole || intracellular non-membrane-bounded organelle || centriole || spindle midzone || nucleus |
| Cellular Component (CC) |
membrane-bounded organelle |
0.9964 |
0.2912 |
-- |
INHERITED FROM: nucleus |
| Cellular Component (CC) |
macromolecular complex |
0.006181 |
0.4276 |
-- |
INHERITED FROM: kinetochore || spindle || spindle pole || protein complex || spindle midzone |
| Cellular Component (CC) |
chromosomal part |
0.01541 |
1.587 |
-- |
INHERITED FROM: kinetochore || chromosome, centromeric region |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
3.129e-15 |
0.6225 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
intracellular organelle part |
1.1e-10 |
0.3893 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
protein complex |
0.0001082 |
0.5639 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
0.3763 |
0.2605 |
Least Informative |
INHERITED FROM: microtubule organizing center part || centriole |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
0.9888 |
0.2961 |
Least Informative |
INHERITED FROM: nucleus |
| Cellular Component (CC) |
cytoskeleton |
6.413e-11 |
1.036 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
microtubule cytoskeleton |
0 |
1.428 |
Informative |
DIRECT |
| Cellular Component (CC) |
chromosome |
0.07901 |
1.462 |
Informative |
INHERITED FROM: kinetochore || chromosome, centromeric region |
| Cellular Component (CC) |
microtubule organizing center |
3.129e-15 |
1.94 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
midbody |
1.227e-13 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
spindle |
3.704e-09 |
1.763 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
kinetochore |
7.956e-09 |
2.064 |
Highly Informative |
DIRECT |
0
