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GAT-like domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Spectrin repeat-like [ 46965] (16)
Superfamily:   GAT-like domain [ 89009] (2)
Families:   GAT domain [ 89010] (3)
  Phosphoinositide-binding clathrin adaptor, domain 2 [ 100929] (2)


Superfamily statistics
Genomes (482) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 4,044 9,024 11
Proteins 4,025 9,000 11


Functional annotation
General category Processes_IC
Detailed category Transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biological regulation 0.8345 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.4287 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.4732 Least Informative Inherited
Biological Process (BP) cellular component organization or biogenesis 0.03038 Least Informative Inherited
Biological Process (BP) regulation of localization 0.03919 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.01965 Moderately Informative Inherited
Biological Process (BP) nitrogen compound transport 0.1267 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.1455 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.1492 Moderately Informative Inherited
Biological Process (BP) regulation of cellular component organization 0.02223 Moderately Informative Inherited
Biological Process (BP) organelle organization 0.4888 Moderately Informative Inherited
Biological Process (BP) organic substance transport 0.4818 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.0203 Moderately Informative Inherited
Biological Process (BP) cellular localization 0.001821 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.02934 Moderately Informative Inherited
Biological Process (BP) protein transport 0.000000000169 Informative Direct
Biological Process (BP) vesicle-mediated transport 0.0000005902 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 0.0001447 Informative Direct
Biological Process (BP) intracellular transport 0.0006629 Informative Direct
Biological Process (BP) proteolysis 0.002955 Informative Inherited
Biological Process (BP) vesicle organization 0.00000005185 Highly Informative Direct
Biological Process (BP) modification-dependent macromolecule catabolic process 0.000007072 Highly Informative Direct
Biological Process (BP) cellular protein catabolic process 0.00005881 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.00002791 Highly Informative Direct
Biological Process (BP) Golgi vesicle transport 0.1044 Highly Informative Inherited
Molecular Function (MF) binding 0.0001358 Least Informative Direct
Molecular Function (MF) anion binding 0.0003167 Moderately Informative Direct
Molecular Function (MF) phospholipid binding 0.000000002373 Informative Direct
Cellular Component (CC) membrane 0.000001339 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.0003697 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.6266 Least Informative Inherited
Cellular Component (CC) endomembrane system 0.0000000000294 Moderately Informative Direct
Cellular Component (CC) vesicle 0.00000000007967 Moderately Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.0002445 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.000009687 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.01795 Moderately Informative Inherited
Cellular Component (CC) Golgi apparatus 0.000007394 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0.0001589 Informative Direct
Cellular Component (CC) membrane region 0.0000006519 Informative Direct
Cellular Component (CC) plasma membrane region 0.05918 Informative Inherited
Cellular Component (CC) coated vesicle 0.000305 Highly Informative Direct
Cellular Component (CC) Golgi subcompartment 0.000002528 Highly Informative Direct
Cellular Component (CC) presynapse 0.0004451 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0Least InformativeDirect
Biological processProtein transport0Moderately InformativeDirect
Biological processEndocytosis0InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentEndosome0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCoated pit0Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0000000001917Least InformativeDirect
Post-translational modificationUbl conjugation0.000003733Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a GAT-like domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the GAT-like domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]