SUPERFAMILY 1.75 HMM library and genome assignments server

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eEF1-gamma domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ferredoxin-like [ 54861] (59)
Superfamily:   eEF1-gamma domain [ 89942]
Families:   eEF1-gamma domain [ 89943]

Superfamily statistics
Genomes (464) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 829 2,479 1
Proteins 820 2,465 1

Functional annotation
General category Information
Detailed category Translation

Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.00002288 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.00005164 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.0006303 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.0004008 Least Informative Direct
Biological Process (BP) primary metabolic process 0.004542 Least Informative Inherited
Biological Process (BP) peptide metabolic process 0.0000000003711 Moderately Informative Direct
Biological Process (BP) gene expression 0.0000002671 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.0000001096 Moderately Informative Direct
Biological Process (BP) amide biosynthetic process 0.0000000003014 Moderately Informative Direct
Cellular Component (CC) cytoplasmic part 0.000009216 Least Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Post-translational modificationElongation factor0Highly InformativeDirect
Post-translational modificationAcetylation0.000000007459Least InformativeDirect
Post-translational modificationIsopeptide bond0.000000002646Moderately InformativeDirect
Post-translational modificationUbl conjugation0.00000005944Moderately InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR001662 SSF89942 Protein matches

This entry represents a conserved domain usually found near the C-terminus of EF1B-gamma chains, a peptide of 410-440 residues. The gamma chain appears to play a role in anchoring the EF1B complex to the beta and delta chains and to other cellular components.

More information about these proteins can be found at Protein of the Month: Elongation Factors.

InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a eEF1-gamma domain domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the eEF1-gamma domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]