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Ran binding protein zinc finger-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   Rubredoxin-like [ 57769] (17)
Superfamily:   Ran binding protein zinc finger-like [ 90209]
Families:   Ran binding protein zinc finger-like [ 90210] (6)


Superfamily statistics
Genomes (512) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 9,011 0 7
Proteins 5,790 0 7


Functional annotation
General category Regulation
Detailed category Other regulatory function

Document:
Function annotation of SCOP domain superfamilies

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0.00000000009655Least InformativeDirect
Enzyme Commission (EC)Omega peptidases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.7706Least InformativeInherited
Disease Ontology (DO)nervous system cancer0.05933Moderately InformativeInherited
Disease Ontology (DO)cell type cancer0.8463Moderately InformativeInherited
Disease Ontology (DO)retinal cell cancer0.0007156Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the digestive system0.1669Least InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.08602Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system physiology0.3171Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.4016Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm by histology0.006182InformativeInherited
Phenotypic Abnormality (PA)Functional abnormality of the gastrointestinal tract0.07385InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.02768Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.1024Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.1102Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.4574Least InformativeInherited
Mammalian Phenotype (MP)abnormal metabolism0.0123Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.02265Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal induced morbidity/mortality0.02725Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.08199Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell morphology0.09987Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal mononuclear cell morphology0.5053Moderately InformativeInherited
Mammalian Phenotype (MP)increased apoptosis0.0001115InformativeDirect
Mammalian Phenotype (MP)abnormal response to radiation0.0001295InformativeDirect
Mammalian Phenotype (MP)abnormal mature B cell morphology0.0001492InformativeDirect
Mammalian Phenotype (MP)abnormal sensitivity to induced morbidity/mortality0.01265InformativeInherited
Mammalian Phenotype (MP)increased mortality induced by ionizing radiation0.000001334Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cell nucleus morphology0.0002917Highly InformativeDirect
Mammalian Phenotype (MP)abnormal B-1 B cell number0.00102Highly InformativeInherited
Mammalian Phenotype (MP)decreased mature B cell number0.4297Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)general pace of development variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)retarded heterochronic variations0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval growth variant0Least InformativeDirect
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.09425Least InformativeInherited
Enzyme Commission (EC)Lyases0.3152Least InformativeInherited
Enzyme Commission (EC)Acyltransferases0.0000000000000508Moderately InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0.0000001163Moderately InformativeDirect
Enzyme Commission (EC)Carbon-oxygen lyases0.04832Moderately InformativeInherited
Enzyme Commission (EC)RING-type E3 ubiquitin transferase0InformativeDirect
Enzyme Commission (EC)Omega peptidases7.448e-16InformativeDirect
Enzyme Commission (EC)DNA-(apurinic or apyrimidinic site) lyase0.000001414Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.5154Least InformativeInherited
Biological processUbl conjugation pathway0Moderately InformativeDirect
Biological processApoptosis0.00000001245Moderately InformativeDirect
Biological processProtein transport0.0000004449Moderately InformativeDirect
Biological processmRNA processing0.00000000000001345InformativeDirect
Biological processWnt signaling pathway0.0000000000003101InformativeDirect
Biological processmRNA transport0.0000000000002425Highly InformativeDirect
Biological processTranslocation0.0003184Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentSpliceosome0.00000000003835InformativeDirect
Coding sequence diversityAlternative splicing0.000322Least InformativeDirect
DiseaseProto-oncogene0.000003168Moderately InformativeDirect
DomainRepeat0.0000009375Least InformativeDirect
DomainZinc-finger0Moderately InformativeDirect
DomainANK repeat0.00005942InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Post-translational modificationHydrolase0.2125Least InformativeInherited
Post-translational modificationRNA-binding0.00000003203Moderately InformativeDirect
Post-translational modificationProtease0.000003302Moderately InformativeDirect
Post-translational modificationThiol protease0.0000000007326InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect
Post-translational modificationAcetylation0.0003033Least InformativeDirect
Post-translational modificationUbl conjugation0.000000000000004307Moderately InformativeDirect
Post-translational modificationMethylation0.0001266Moderately InformativeDirect
Post-translational modificationIsopeptide bond0.0007612Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Ran binding protein zinc finger-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 6 hidden Markov models representing the Ran binding protein zinc finger-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]