SUPERFAMILY 1.75 HMM library and genome assignments server

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HD domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   HD-domain/PDEase-like [ 109603]
Superfamily:   HD-domain/PDEase-like [ 109604] (5)
Family:   HD domain [ 101340] (13)


Family statistics
Genomes (2,607) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 5,223 29,956 14
Proteins 5,223 29,955 14


Gene Ontology (high-coverage)

(
show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) organonitrogen compound metabolic process 0.5205 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.008769 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.8838 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 0.01185 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 0.04899 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.003483 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.003954 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.8407 Least Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.00000000003364 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.000000537 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.000002585 Moderately Informative Direct
Biological Process (BP) response to external stimulus 0.0008129 Moderately Informative Direct
Biological Process (BP) single-organism catabolic process 0.0008635 Moderately Informative Direct
Biological Process (BP) response to stress 0.006278 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.454 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.01009 Moderately Informative Inherited
Biological Process (BP) cell communication 0.6323 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.1192 Moderately Informative Inherited
Biological Process (BP) cellular response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.001094 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.01733 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.0000000452 Informative Direct
Biological Process (BP) cellular nitrogen compound catabolic process 0.0000013 Informative Direct
Biological Process (BP) heterocycle catabolic process 0.000002423 Informative Direct
Biological Process (BP) aromatic compound catabolic process 0.000004821 Informative Direct
Biological Process (BP) organic cyclic compound catabolic process 0.000005715 Informative Direct
Biological Process (BP) organonitrogen compound catabolic process 0.0003632 Informative Direct
Biological Process (BP) response to other organism 0.008337 Informative Inherited
Biological Process (BP) defense response 0.06381 Informative Inherited
Biological Process (BP) regulation of immune system process 0.004688 Informative Inherited
Biological Process (BP) regulation of response to stress 0.004614 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 0.1945 Informative Inherited
Biological Process (BP) deoxyribose phosphate metabolic process 0.00000000000001867 Highly Informative Direct
Biological Process (BP) purine-containing compound catabolic process 0.00000000008739 Highly Informative Direct
Biological Process (BP) deoxyribonucleotide metabolic process 0.0000000001685 Highly Informative Direct
Biological Process (BP) nucleoside phosphate catabolic process 0.0000000001964 Highly Informative Direct
Biological Process (BP) response to virus 0.00000005147 Highly Informative Direct
Biological Process (BP) response to nutrient levels 0.00007326 Highly Informative Direct
Biological Process (BP) cellular response to external stimulus 0.006333 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 0.003529 Least Informative Inherited
Molecular Function (MF) transferase activity 0.4908 Least Informative Inherited
Molecular Function (MF) hydrolase activity, acting on ester bonds 0.000000001777 Moderately Informative Direct
Molecular Function (MF) metal ion binding 0.00005923 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 0.6634 Moderately Informative Inherited
Molecular Function (MF) heterocyclic compound binding 0.6351 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.1908 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.004388 Moderately Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.02091 Moderately Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.0007301 Informative Direct
Molecular Function (MF) nucleotide binding 0.0007667 Informative Direct
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) plastid 0.0004896 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Diphosphotransferases0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processStress response0.00000118InformativeDirect
Biological processImmunity0.000284InformativeDirect
Biological processAntiviral defense0.00000003181Highly InformativeDirect
DomainTransit peptide0.00006691Moderately InformativeDirect
Molecular functionNucleotide-binding0.00271Least InformativeInherited
Molecular functionManganese0.00001102Moderately InformativeDirect
Molecular functionGTP-binding0.000000000003174InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationKinase0.00000000169Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 24 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a HD-domain/PDEase-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]