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BAR/IMD domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   BAR/IMD domain-like [ 116747]
Superfamily:   BAR/IMD domain-like [ 103657] (4)
Families:   BAR domain [ 103658] (3)
  Arfaptin, Rac-binding fragment [ 64599]
  IMD domain [ 140703]
  FCH domain [ 158645] (2)


Superfamily statistics
Genomes (540) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 13,774 15,237 12
Proteins 13,566 15,090 12


Functional annotation
General category General
Detailed category Protein interaction

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)single-organism cellular process0.22290.00000000000002582Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.015280Least InformativeInherited
Biological Process (BP)organelle organization0.057951Moderately InformativeInherited
Biological Process (BP)actin filament-based process0.00014470.00000000002689InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.00000000000002582 Least Informative Direct
Biological Process (BP) biological regulation 0.000000000000003692 Least Informative Direct
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 0.5976 Least Informative Inherited
Biological Process (BP) cellular developmental process 0.00000007914 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0.000007063 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0 Moderately Informative Direct
Biological Process (BP) cellular localization 0.00000001921 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.00009395 Moderately Informative Direct
Biological Process (BP) signaling 0.0005507 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) cellular component assembly 0.01153 Moderately Informative Inherited
Biological Process (BP) regulation of developmental process 0.01162 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.493 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.06801 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.3443 Moderately Informative Inherited
Biological Process (BP) regulation of multicellular organismal process 0.4297 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 0.125 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.6862 Moderately Informative Inherited
Biological Process (BP) response to stress 1 Moderately Informative Inherited
Biological Process (BP) cell communication 0.4491 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.08532 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.8829 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.02247 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of gene expression 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 1 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.503 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) system development 0.9692 Moderately Informative Inherited
Biological Process (BP) reproduction 0.04357 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.03398 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) single-organism transport 0.9822 Moderately Informative Inherited
Biological Process (BP) actin filament-based process 0.00000000002689 Informative Direct
Biological Process (BP) vesicle-mediated transport 0 Informative Direct
Biological Process (BP) cytoskeleton organization 0.00001018 Informative Direct
Biological Process (BP) regulation of anatomical structure size 0 Informative Direct
Biological Process (BP) single-organism membrane organization 0 Informative Direct
Biological Process (BP) regulation of cellular component biogenesis 0 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.000000000001921 Informative Direct
Biological Process (BP) regulation of nervous system development 0.00000000001819 Informative Direct
Biological Process (BP) epithelium development 0.0000009476 Informative Direct
Biological Process (BP) regulation of growth 0.000003322 Informative Direct
Biological Process (BP) multi-organism reproductive process 0.00003834 Informative Direct
Biological Process (BP) negative regulation of multicellular organismal process 0.0007942 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.1489 Informative Inherited
Biological Process (BP) regulation of locomotion 0.3088 Informative Inherited
Biological Process (BP) regulation of cell differentiation 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.003578 Informative Inherited
Biological Process (BP) cellular component morphogenesis 0.09842 Informative Inherited
Biological Process (BP) system process 1 Informative Inherited
Biological Process (BP) regulation of intracellular signal transduction 0.7567 Informative Inherited
Biological Process (BP) negative regulation of cell communication 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 1 Informative Inherited
Biological Process (BP) regulation of cell proliferation 1 Informative Inherited
Biological Process (BP) animal organ morphogenesis 0.6692 Informative Inherited
Biological Process (BP) post-embryonic development 0.05502 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.009122 Informative Inherited
Biological Process (BP) multicellular organism reproduction 0.003161 Informative Inherited
Biological Process (BP) negative regulation of transport 0.1375 Informative Inherited
Biological Process (BP) positive regulation of catalytic activity 0.09551 Informative Inherited
Biological Process (BP) regulation of hydrolase activity 0.004242 Informative Inherited
Biological Process (BP) single-organism intracellular transport 0.2109 Informative Inherited
Biological Process (BP) protein localization to organelle 1 Informative Inherited
Biological Process (BP) generation of neurons 0.6902 Informative Inherited
Biological Process (BP) positive regulation of immune system process 0.4276 Informative Inherited
Biological Process (BP) regulation of immune response 0.7123 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.006033 Informative Inherited
Biological Process (BP) cell cycle process 0.8179 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.5358 Informative Inherited
Biological Process (BP) single organism reproductive process 0.2036 Informative Inherited
Biological Process (BP) regulation of transcription, DNA-templated 1 Informative Inherited
Biological Process (BP) peptidyl-amino acid modification 0.7405 Informative Inherited
Biological Process (BP) phosphorylation 0.6067 Informative Inherited
Biological Process (BP) nitrogen compound transport 1 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 1 Informative Inherited
Biological Process (BP) cellular response to hormone stimulus 0.375 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.5238 Informative Inherited
Biological Process (BP) response to nitrogen compound 1 Informative Inherited
Biological Process (BP) cell surface receptor signaling pathway 1 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.4265 Informative Inherited
Biological Process (BP) cell development 0.006763 Informative Inherited
Biological Process (BP) intracellular signal transduction 0.754 Informative Inherited
Biological Process (BP) positive regulation of transport 0.01114 Informative Inherited
Biological Process (BP) organelle assembly 0.4506 Informative Inherited
Biological Process (BP) mitotic cell cycle 0.2165 Informative Inherited
Biological Process (BP) cell projection organization 0 Highly Informative Direct
Biological Process (BP) endomembrane system organization 0 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.00000000000001409 Highly Informative Direct
Biological Process (BP) endosomal transport 0.000000000001054 Highly Informative Direct
Biological Process (BP) epithelial cell differentiation 0.00000000005978 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 0.000000003358 Highly Informative Direct
Biological Process (BP) instar larval or pupal morphogenesis 0.00000000355 Highly Informative Direct
Biological Process (BP) negative regulation of growth 0.000000005573 Highly Informative Direct
Biological Process (BP) positive regulation of GTPase activity 0.000000008033 Highly Informative Direct
Biological Process (BP) tube morphogenesis 0.00000002914 Highly Informative Direct
Biological Process (BP) female gamete generation 0.0000000947 Highly Informative Direct
Biological Process (BP) metamorphosis 0.000001118 Highly Informative Direct
Biological Process (BP) lysosome organization 0.000001252 Highly Informative Direct
Biological Process (BP) positive regulation of cellular component biogenesis 0.000003851 Highly Informative Direct
Biological Process (BP) regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 0.00002415 Highly Informative Direct
Biological Process (BP) morphogenesis of an epithelium 0.00002983 Highly Informative Direct
Biological Process (BP) regulation of epithelial cell proliferation 0.00004571 Highly Informative Direct
Biological Process (BP) appendage development 0.000113 Highly Informative Direct
Biological Process (BP) vesicle localization 0.0001216 Highly Informative Direct
Biological Process (BP) synaptic signaling 0.0001501 Highly Informative Direct
Biological Process (BP) small GTPase mediated signal transduction 0.0001699 Highly Informative Direct
Biological Process (BP) cell proliferation 0.0002604 Highly Informative Direct
Biological Process (BP) regulation of cell shape 0.0002948 Highly Informative Direct
Biological Process (BP) germ cell development 0.000694 Highly Informative Direct
Biological Process (BP) positive regulation of organelle organization 0.7542 Highly Informative Inherited
Biological Process (BP) cellular response to growth factor stimulus 0.06499 Highly Informative Inherited
Biological Process (BP) vesicle organization 0.001173 Highly Informative Inherited
Biological Process (BP) organelle fusion 0.05156 Highly Informative Inherited
Biological Process (BP) single-organism membrane fusion 1 Highly Informative Inherited
Biological Process (BP) heart contraction 0.001196 Highly Informative Inherited
Biological Process (BP) establishment of organelle localization 0.01075 Highly Informative Inherited
Biological Process (BP) negative regulation of cytoskeleton organization 0.0105 Highly Informative Inherited
Biological Process (BP) regulation of actin filament polymerization 0.004265 Highly Informative Inherited
Biological Process (BP) actin filament organization 0.005411 Highly Informative Inherited
Biological Process (BP) negative regulation of cell proliferation 0.3175 Highly Informative Inherited
Biological Process (BP) response to nutrient levels 0.01868 Highly Informative Inherited
Biological Process (BP) cellular response to external stimulus 0.04788 Highly Informative Inherited
Biological Process (BP) positive regulation of immune effector process 0.001325 Highly Informative Inherited
Biological Process (BP) cell division 0.09182 Highly Informative Inherited
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.001349 Highly Informative Inherited
Biological Process (BP) regulation of transcription from RNA polymerase II promoter 0.8623 Highly Informative Inherited
Biological Process (BP) response to peptide hormone 0.1574 Highly Informative Inherited
Biological Process (BP) cellular response to organonitrogen compound 0.2284 Highly Informative Inherited
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0.2289 Highly Informative Inherited
Biological Process (BP) G-protein coupled receptor signaling pathway 0.5994 Highly Informative Inherited
Biological Process (BP) muscle system process 0.01583 Highly Informative Inherited
Biological Process (BP) endocytosis 0.02033 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) protein binding 0.0006938 Moderately Informative Direct
Molecular Function (MF) anion binding 0 Moderately Informative Direct
Molecular Function (MF) molecular function regulator 0.00000000000002146 Moderately Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 1 Moderately Informative Inherited
Molecular Function (MF) phospholipid binding 0 Informative Direct
Molecular Function (MF) enzyme activator activity 0.000000000002565 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.00000006935 Informative Direct
Molecular Function (MF) macromolecular complex binding 0.7768 Informative Inherited
Molecular Function (MF) enzyme binding 0.2481 Informative Inherited
Molecular Function (MF) transferase activity, transferring acyl groups 0.0037 Informative Inherited
Molecular Function (MF) kinase activity 1 Informative Inherited
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 1 Informative Inherited
Molecular Function (MF) GTPase regulator activity 0 Highly Informative Direct
Molecular Function (MF) modified amino acid binding 0.00007698 Highly Informative Direct
Molecular Function (MF) small GTPase binding 1 Highly Informative Inherited
Molecular Function (MF) phosphatidylinositol bisphosphate binding 0.9376 Highly Informative Inherited
Molecular Function (MF) protein kinase activity 0.9805 Highly Informative Inherited
Cellular Component (CC) cytoplasmic part 0.0000000000000175 Least Informative Direct
Cellular Component (CC) membrane 0 Least Informative Direct
Cellular Component (CC) protein complex 0.2209 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.9942 Least Informative Inherited
Cellular Component (CC) vesicle 0 Moderately Informative Direct
Cellular Component (CC) organelle membrane 0.000000000002477 Moderately Informative Direct
Cellular Component (CC) cytoskeleton 0.000000000159 Moderately Informative Direct
Cellular Component (CC) whole membrane 0.000000001472 Moderately Informative Direct
Cellular Component (CC) cell projection 0.0000002036 Moderately Informative Direct
Cellular Component (CC) plasma membrane 0.0000007544 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0.2503 Moderately Informative Inherited
Cellular Component (CC) synapse 0 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0 Informative Direct
Cellular Component (CC) endosome 0.0000000000001603 Informative Direct
Cellular Component (CC) actin cytoskeleton 0.0000000003318 Informative Direct
Cellular Component (CC) cell junction 0.000000002907 Informative Direct
Cellular Component (CC) extrinsic component of membrane 0.0000005316 Informative Direct
Cellular Component (CC) cytoplasmic region 0.000006031 Informative Direct
Cellular Component (CC) membrane region 0.0001924 Informative Direct
Cellular Component (CC) side of membrane 0.01622 Informative Inherited
Cellular Component (CC) cell surface 0.01653 Informative Inherited
Cellular Component (CC) cell projection part 0.001096 Informative Inherited
Cellular Component (CC) neuron projection 0.437 Informative Inherited
Cellular Component (CC) cell division site 0 Highly Informative Direct
Cellular Component (CC) midbody 0.0000000007276 Highly Informative Direct
Cellular Component (CC) endosome membrane 0.000000001099 Highly Informative Direct
Cellular Component (CC) extrinsic component of cytoplasmic side of plasma membrane 0.000000005982 Highly Informative Direct
Cellular Component (CC) ruffle 0.00004854 Highly Informative Direct
Cellular Component (CC) dendrite 1 Highly Informative Inherited
Cellular Component (CC) anchoring junction 0.001074 Highly Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Non-specific protein-tyrosine kinase0InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.4101Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.8119Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.8727Least InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.3663Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system physiology0.3705Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology0.473Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell morphology0.4814Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.5923Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal myeloid cell morphology0.6701Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.01126InformativeInherited
Mammalian Phenotype (MP)abnormal neuron physiology0.1079InformativeInherited
Mammalian Phenotype (MP)abnormal spermatogenesis0.2395InformativeInherited
Mammalian Phenotype (MP)abnormal germ cell morphology0.2452InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic vesicle recycling0.00000005908Highly InformativeDirect
Mammalian Phenotype (MP)decreased excitatory postsynaptic current amplitude0.00000774Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spermiogenesis0.0008952Highly InformativeDirect
Mammalian Phenotype (MP)abnormal synapse morphology0.002601Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hematocrit0.006201Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.06231Least InformativeInherited
Worm Phenotype (WP)organ system morphology variant0.06457Least InformativeInherited
Worm Phenotype (WP)cell development variant0.1499Least InformativeInherited
Worm Phenotype (WP)apoptosis variant0.0001639Moderately InformativeDirect
Worm Phenotype (WP)nervous system morphology variant0.005475Moderately InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.2055Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.4793Moderately InformativeInherited
Worm Phenotype (WP)accumulated germline cell corpses0.00001705InformativeDirect
Worm Phenotype (WP)cytokinesis variant emb0.009598InformativeInherited
Worm Phenotype (WP)alimentary system development variant0.04588InformativeInherited
Worm Phenotype (WP)sensillum morphology variant0.1093InformativeInherited
Worm Phenotype (WP)gut granule development variant0.0001849Highly InformativeDirect
Worm Phenotype (WP)cytokinesis defective early emb0.004969Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)cell0.306Least InformativeInherited
Fly Anatomy (FA)nervous system0.3826Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.4437Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.08532Moderately InformativeInherited
Fly Anatomy (FA)neuron0.09279Moderately InformativeInherited
Fly Anatomy (FA)cell component0.00783InformativeInherited
Fly Anatomy (FA)bouton0.0001209Highly InformativeDirect
Fly Anatomy (FA)neuromuscular junction0.0001939Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)guard cell0Least InformativeDirect
Plant ANatomical entity (PAN)shoot axis0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring phosphorus-containing groups0Least InformativeDirect
Enzyme Commission (EC)Protein-tyrosine kinases0InformativeDirect
Enzyme Commission (EC)Non-specific protein-tyrosine kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.005465Least InformativeInherited
Biological processProtein transport0Moderately InformativeDirect
Biological processCell cycle0.0008725Moderately InformativeDirect
Biological processDifferentiation0.0009759Moderately InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processAutophagy0.00000000000002568InformativeDirect
Biological processNeurogenesis0.0000000000001524InformativeDirect
Biological processSeptation0.00008984Highly InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCytoplasm0.000000000000004493Least InformativeDirect
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentGolgi apparatus0Moderately InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentEndosome0Moderately InformativeDirect
Cellular componentCytoplasmic vesicle0Moderately InformativeDirect
Cellular componentMitochondrion1Moderately InformativeInherited
Cellular componentLysosome0.0000001382InformativeDirect
Cellular componentMitochondrion outer membrane0.0000363InformativeDirect
Cellular componentCoated pit0.0000000000007009Highly InformativeDirect
Coding sequence diversityAlternative splicing0.0001003Least InformativeDirect
Coding sequence diversityChromosomal rearrangement0.0001999InformativeDirect
DiseaseProto-oncogene0.00004135Moderately InformativeDirect
DiseaseTumor suppressor0.0003681Moderately InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
DomainSH3 domain0InformativeDirect
DomainANK repeat0.00000000000138InformativeDirect
DomainSH2 domain0.00000002585InformativeDirect
DomainSH3-binding0.00007671InformativeDirect
Molecular functionLipid-binding0Moderately InformativeDirect
Molecular functionActin-binding0.00000000002067InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationKinase0.8849Moderately InformativeInherited
Post-translational modificationGTPase activation0InformativeDirect
Post-translational modificationGuanine-nucleotide releasing factor0.0000004211InformativeDirect
Post-translational modificationTyrosine-protein kinase0.000000000002414Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a BAR/IMD domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 8 hidden Markov models representing the BAR/IMD domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]