SUPERFAMILY 1.75 HMM library and genome assignments server

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BAR domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   BAR/IMD domain-like [ 116747]
Superfamily:   BAR/IMD domain-like [ 103657] (4)
Family:   BAR domain [ 103658] (3)


Family statistics
Genomes (146) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 897 2,236 7
Proteins 895 2,228 7


Gene Ontology (high-coverage)

(
show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) biological regulation 0.6464 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.4684 Least Informative Inherited
Biological Process (BP) transport 0.000001469 Moderately Informative Direct
Biological Process (BP) cellular response to stimulus 0.3971 Moderately Informative Inherited
Biological Process (BP) response to chemical 0.8325 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 0.399 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 0.314 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 0.3421 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 0.3469 Moderately Informative Inherited
Biological Process (BP) regulation of response to stimulus 0.932 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.9394 Moderately Informative Inherited
Biological Process (BP) single-organism localization 0.002773 Moderately Informative Inherited
Biological Process (BP) regulation of molecular function 0.2758 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of primary metabolic process 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.5837 Moderately Informative Inherited
Biological Process (BP) reproduction 0.7723 Moderately Informative Inherited
Biological Process (BP) multi-organism process 0.9089 Moderately Informative Inherited
Biological Process (BP) vesicle-mediated transport 0.00000000000007569 Informative Direct
Biological Process (BP) membrane organization 0.000001246 Informative Direct
Biological Process (BP) cellular response to organic substance 0.09379 Informative Inherited
Biological Process (BP) cellular response to endogenous stimulus 0.02467 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 0.3338 Informative Inherited
Biological Process (BP) regulation of intracellular signal transduction 0.08461 Informative Inherited
Biological Process (BP) intracellular transport 0.1847 Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.07663 Informative Inherited
Biological Process (BP) regulation of hydrolase activity 0.008355 Informative Inherited
Biological Process (BP) single-organism cellular localization 0.00274 Informative Inherited
Biological Process (BP) cellular protein localization 0.7876 Informative Inherited
Biological Process (BP) sexual reproduction 0.1544 Informative Inherited
Biological Process (BP) multicellular organism reproduction 0.5136 Informative Inherited
Biological Process (BP) single organism reproductive process 0.7118 Informative Inherited
Biological Process (BP) system process 0.1937 Informative Inherited
Biological Process (BP) endocytosis 0.0000001177 Highly Informative Direct
Biological Process (BP) single-organism intracellular transport 0.0000003538 Highly Informative Direct
Biological Process (BP) endomembrane system organization 0.000005205 Highly Informative Direct
Biological Process (BP) establishment of organelle localization 0.00002414 Highly Informative Direct
Biological Process (BP) blood circulation 0.0002298 Highly Informative Direct
Biological Process (BP) regulation of cellular carbohydrate metabolic process 0.0005821 Highly Informative Direct
Biological Process (BP) cell projection organization 0.02419 Highly Informative Inherited
Biological Process (BP) heart process 0.001962 Highly Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.007993 Highly Informative Inherited
Biological Process (BP) cellular process involved in reproduction in multicellular organism 0.05531 Highly Informative Inherited
Molecular Function (MF) binding 0.00001601 Least Informative Direct
Molecular Function (MF) transferase activity 0.9349 Least Informative Inherited
Molecular Function (MF) anion binding 0.000000000002024 Moderately Informative Direct
Molecular Function (MF) protein binding 0.3928 Moderately Informative Inherited
Molecular Function (MF) lipid binding 0 Informative Direct
Molecular Function (MF) enzyme regulator activity 0.00000002065 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0.0000003604 Informative Direct
Molecular Function (MF) enzyme binding 0.2803 Informative Inherited
Molecular Function (MF) phospholipid binding 0.00000000000001695 Highly Informative Direct
Molecular Function (MF) enzyme activator activity 0.000000000001151 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.00003714 Least Informative Direct
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) non-membrane-bounded organelle 0.5006 Least Informative Inherited
Cellular Component (CC) membrane 0.01137 Least Informative Inherited
Cellular Component (CC) vesicle 0.000000000117 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.000001326 Moderately Informative Direct
Cellular Component (CC) cell projection 0.008954 Moderately Informative Inherited
Cellular Component (CC) cytoskeleton 0.001418 Moderately Informative Inherited
Cellular Component (CC) organelle membrane 0.01541 Moderately Informative Inherited
Cellular Component (CC) endosome 0.00000123 Informative Direct
Cellular Component (CC) cytoplasmic vesicle part 0.00007292 Informative Direct
Cellular Component (CC) actin cytoskeleton 0.00013 Informative Direct
Cellular Component (CC) neuron part 0.0002066 Informative Direct
Cellular Component (CC) plasma membrane bounded cell projection part 0.0003072 Informative Direct
Cellular Component (CC) bounding membrane of organelle 0.0004806 Informative Direct
Cellular Component (CC) whole membrane 0.004053 Informative Inherited
Cellular Component (CC) secretory vesicle 0.7864 Informative Inherited
Cellular Component (CC) synapse part 0.0000001711 Highly Informative Direct
Cellular Component (CC) endosomal part 0.01566 Highly Informative Inherited
Cellular Component (CC) transport vesicle 0.006276 Highly Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCell cycle0.0003141Moderately InformativeDirect
Biological processEndocytosis0InformativeDirect
Biological processApoptosis0.00002507InformativeDirect
Biological processSeptation0.00000125Highly InformativeDirect
Cellular componentMembrane0.00000000000009631Least InformativeDirect
Cellular componentCytoplasm0.0000001108Least InformativeDirect
Cellular componentCell junction0Moderately InformativeDirect
Cellular componentCell projection0Moderately InformativeDirect
Cellular componentCytoskeleton0.00000000000001166Moderately InformativeDirect
Cellular componentGolgi apparatus0.00000003997Moderately InformativeDirect
Cellular componentMitochondrion0.3715Moderately InformativeInherited
Cellular componentEndosome0InformativeDirect
Cellular componentCytoplasmic vesicle0.0000000316InformativeDirect
Cellular componentMitochondrion outer membrane0.00000003274Highly InformativeDirect
DomainCoiled coil0Moderately InformativeDirect
DomainANK repeat0InformativeDirect
DomainSH3 domain0InformativeDirect
Molecular functionZinc0.0002427Least InformativeDirect
Molecular functionLipid-binding0InformativeDirect
Post-translational modificationGTPase activation0Highly InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a BAR/IMD domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]