SUPERFAMILY 1.75 HMM library and genome assignments server

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DEK C-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Another 3-helical bundle [ 81602] (5)
Superfamily:   DEK C-terminal domain [ 109715]
Families:   DEK C-terminal domain [ 109716]


Superfamily statistics
Genomes (435) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,402 3,688 1
Proteins 1,400 3,684 1


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Cellular Component (CC) intracellular membrane-bounded organelle 0.03256 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.1176 Least Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.001294 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.001888 Moderately Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0.000000002607Least InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0.0000000000001604Moderately InformativeDirect
Enzyme Commission (EC)Phosphoprotein phosphatase0InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentNucleus0.00000306Least InformativeDirect
Cellular componentCytoplasm0.5599Least InformativeInherited
Cellular componentCytoskeleton0.00000000002002Moderately InformativeDirect
Coding sequence diversityAlternative splicing0.000001329Least InformativeDirect
Post-translational modificationHydrolase0.0008325Least InformativeDirect
Post-translational modificationProtein phosphatase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a DEK C-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the DEK C-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]