SUPERFAMILY 1.75 HMM library and genome assignments server

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Surp module (SWAP domain) superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Surp module (SWAP domain) [ 109904]
Superfamily:   Surp module (SWAP domain) [ 109905]
Families:   Surp module (SWAP domain) [ 109906] (3)


Superfamily statistics
Genomes (514) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,328 7,459 5
Proteins 2,287 5,176 5


Functional annotation
General category Regulation
Detailed category RNA binding, metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) heterocycle metabolic process 0.00002839 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.00003257 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.00007825 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.0001153 Least Informative Direct
Biological Process (BP) primary metabolic process 0.08321 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.005967 Least Informative Inherited
Biological Process (BP) RNA metabolic process 0.00000000113 Moderately Informative Direct
Biological Process (BP) gene expression 0.000000009106 Moderately Informative Direct
Biological Process (BP) mRNA processing 0.00000957 Highly Informative Direct
Biological Process (BP) RNA splicing 0.00002344 Highly Informative Direct
Molecular Function (MF) binding 0.00854 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.0000000003863 Moderately Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Cellular Component (CC) intracellular organelle part 0.0001122 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.0117 Least Informative Inherited
Cellular Component (CC) nuclear part 0.0000002135 Moderately Informative Direct
Cellular Component (CC) spliceosomal complex 0.00000001398 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processmRNA processing0InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentSpliceosome0InformativeDirect
DomainRepeat0.000003012Least InformativeDirect
DomainCoiled coil0.00008915Moderately InformativeDirect
Post-translational modificationRNA-binding0.0000001417Moderately InformativeDirect
Post-translational modificationAcetylation0.000001719Least InformativeDirect
Post-translational modificationPhosphoprotein0.000006318Least InformativeDirect
Post-translational modificationIsopeptide bond0.0000000004684Moderately InformativeDirect
Post-translational modificationUbl conjugation0.00000002672Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Surp module (SWAP domain) domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Surp module (SWAP domain) superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]