SUPERFAMILY 1.75 HMM library and genome assignments server

  Home > SCOP hierarchy > Glycolipid transfer protein, GLTP superfamily


Glycolipid transfer protein, GLTP superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Glycolipid transfer protein, GLTP [ 110003]
Superfamily:   Glycolipid transfer protein, GLTP [ 110004]
Families:   Glycolipid transfer protein, GLTP [ 110005]

 Superfamily statistics
Genomes (373) Uniprot 2013_05 PDB chains (SCOP 1.75)
Domains 1,149 911 1
Proteins 1,137 905 1

 Functional annotation
General category Processes_IC
Detailed category Transport

Document: Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)localization7.93e-053.342e-07Least InformativeDirect
Biological Process (BP)macromolecule localization0.0040596.332e-05Moderately InformativeInherited
Biological Process (BP)organic substance transport0.036580.0006316Moderately InformativeInherited
Biological Process (BP)lipid transport2.623e-061.282e-12InformativeDirect
Molecular Function (MF)binding0.20480.05845Least InformativeInherited
Molecular Function (MF)transporter activity0.00011347.536e-10Moderately InformativeDirect
Molecular Function (MF)lipid binding1.71e-056.673e-13InformativeDirect
Molecular Function (MF)lipid transporter activity1.493e-100Highly InformativeDirect
Molecular Function (MF)glycolipid binding1.498e-090Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) localization 3.342e-07 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.5532 Least Informative Inherited
Biological Process (BP) macromolecule localization 6.332e-05 Moderately Informative Direct
Biological Process (BP) organic substance transport 0.0006316 Moderately Informative Direct
Biological Process (BP) cellular localization 0.001521 Moderately Informative Inherited
Biological Process (BP) lipid transport 1.282e-12 Informative Direct
Biological Process (BP) nitrogen compound transport 0.009148 Informative Inherited
Molecular Function (MF) binding 0.05845 Least Informative Inherited
Molecular Function (MF) transporter activity 7.536e-10 Moderately Informative Direct
Molecular Function (MF) anion binding 3.922e-05 Moderately Informative Direct
Molecular Function (MF) lipid binding 6.673e-13 Informative Direct
Molecular Function (MF) lipid transporter activity 0 Highly Informative Direct
Molecular Function (MF) glycolipid binding 0 Highly Informative Direct
Molecular Function (MF) phosphatidylinositol binding 2.809e-10 Highly Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.473 Least Informative Inherited
Cellular Component (CC) trans-Golgi network 6.301e-10 Highly Informative Direct

Document: GO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)growth variant0Least InformativeDirect
Worm Phenotype (WP)developmental timing variant0Least InformativeDirect
Worm Phenotype (WP)larval development variant0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Moderately InformativeDirect
Worm Phenotype (WP)sterile progeny0Moderately InformativeDirect

Document: WP annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport6.917e-16Least InformativeDirect
Biological processLipid transport0InformativeDirect
Cellular componentCytoplasm1.332e-07Least InformativeDirect
Cellular componentGolgi apparatus5.725e-10Moderately InformativeDirect
DomainRepeat1.423e-06Least InformativeDirect
Molecular functionLipid-binding3.428e-11InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR014830 SSF110004 Protein matches
Abstract

Glycolipid transfer protein (GLTP) is a cytosolic protein that catalyses the intermembrane transfer of glycolipids such as glycosphingolipids, glyceroglycolipids, and possibly glucosylceramides, but not of phospholipids. GLTP has a multi-helical structure consisting of two layers of orthogonally packed helices [PubMed15504043, PubMed16309699].


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Glycolipid transfer protein, GLTP domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Glycolipid transfer protein, GLTP superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Worm Phenotype (WP) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

Please send feedback, comments or questions to superfamily@cs.bris.ac.uk or use the feedback form.

© Copyright 2013 The SUPERFAMILY authors and Julian Gough.