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Cell cycle arrest protein BUB3 family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   WD40 repeat-like [ 50978] (2)
Family:   Cell cycle arrest protein BUB3 [ 110289]


Family statistics
Genomes (42) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 43 75 4
Proteins 43 75 4


Gene Ontology (high-quality)

(
show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biological regulation0.0000000012670.00009354Least InformativeDirect
Biological Process (BP)single-organism cellular process0.055570.2725Least InformativeInherited
Biological Process (BP)macromolecule metabolic process0.16260.4973Least InformativeInherited
Biological Process (BP)negative regulation of biological process0.11950.1693Moderately InformativeInherited
Biological Process (BP)macromolecule localization0.00014270.001091Moderately InformativeInherited
Biological Process (BP)transport0.095370.1409Moderately InformativeInherited
Biological Process (BP)gene expression0.0021170.01161Moderately InformativeInherited
Biological Process (BP)cell cycle0.0000000000000011680.000000000003882InformativeDirect
Biological Process (BP)protein transport0.000058420.0001475InformativeDirect
Biological Process (BP)regulation of organelle organization0.000028950.00001143InformativeDirect
Biological Process (BP)cellular protein localization0.0000076090.00006587InformativeDirect
Biological Process (BP)regulation of cell cycle00InformativeDirect
Biological Process (BP)intracellular transport0.00068270.00122InformativeInherited
Biological Process (BP)cell cycle checkpoint00.00000000000003497Highly InformativeDirect
Biological Process (BP)nucleocytoplasmic transport0.000000082680.000000381Highly InformativeDirect
Biological Process (BP)nucleobase-containing compound transport0.000000029890.00000002376Highly InformativeDirect
Biological Process (BP)establishment of RNA localization0.00000000078440.000000006429Highly InformativeDirect
Biological Process (BP)regulation of chromosome segregation0.000000000000004450Highly InformativeDirect
Biological Process (BP)ribonucleoprotein complex localization0.00000003250.00000003161Highly InformativeDirect
Biological Process (BP)negative regulation of mitotic cell cycle0.16580.1772Highly InformativeInherited
Biological Process (BP)negative regulation of organelle organization0.0091860.0114Highly InformativeInherited
Biological Process (BP)regulation of mitotic nuclear division0.029690.01678Highly InformativeInherited
Biological Process (BP)regulation of chromosome organization0.0025650.01587Highly InformativeInherited
Biological Process (BP)regulation of mitotic cell cycle phase transition0.63560.2126Highly InformativeInherited
Biological Process (BP)negative regulation of cell cycle process0.062990.0791Highly InformativeInherited
Biological Process (BP)mitotic cell cycle process0.015640.009395Highly InformativeInherited
Cellular Component (CC)macromolecular complex0.0000045140.00007214Least InformativeDirect
Cellular Component (CC)non-membrane-bounded organelle0.000005110.00004407Least InformativeDirect
Cellular Component (CC)intracellular organelle part0.00000000045390.000000009256Least InformativeDirect
Cellular Component (CC)intracellular membrane-bounded organelle11Least InformativeInherited
Cellular Component (CC)cytoskeleton0.047040.1183Moderately InformativeInherited
Cellular Component (CC)endomembrane system0.072520.09108Moderately InformativeInherited
Cellular Component (CC)envelope0.0062280.0007457Moderately InformativeInherited
Cellular Component (CC)nuclear part0.00021310.001915Moderately InformativeInherited
Cellular Component (CC)nuclear envelope0.000011330.00001025InformativeDirect
Cellular Component (CC)microtubule cytoskeleton0.000000000041260.000000007057InformativeDirect
Cellular Component (CC)chromosome0.00023450.0121InformativeInherited
Cellular Component (CC)cytoskeletal part0.00096820.007576InformativeInherited
Cellular Component (CC)kinetochore0.00000000015620.00000000002276Highly InformativeDirect
Cellular Component (CC)spindle0.000000033610.00000005188Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biological regulation 0.00009354 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.2725 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.4973 Least Informative Inherited
Biological Process (BP) negative regulation of biological process 0.1693 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 0.001091 Moderately Informative Inherited
Biological Process (BP) transport 0.1409 Moderately Informative Inherited
Biological Process (BP) gene expression 0.01161 Moderately Informative Inherited
Biological Process (BP) cell cycle 0.000000000003882 Informative Direct
Biological Process (BP) protein transport 0.0001475 Informative Direct
Biological Process (BP) regulation of organelle organization 0.00001143 Informative Direct
Biological Process (BP) cellular protein localization 0.00006587 Informative Direct
Biological Process (BP) regulation of cell cycle 0 Informative Direct
Biological Process (BP) intracellular transport 0.00122 Informative Inherited
Biological Process (BP) cell cycle checkpoint 0.00000000000003497 Highly Informative Direct
Biological Process (BP) nucleocytoplasmic transport 0.000000381 Highly Informative Direct
Biological Process (BP) nucleobase-containing compound transport 0.00000002376 Highly Informative Direct
Biological Process (BP) establishment of RNA localization 0.000000006429 Highly Informative Direct
Biological Process (BP) regulation of chromosome segregation 0 Highly Informative Direct
Biological Process (BP) ribonucleoprotein complex localization 0.00000003161 Highly Informative Direct
Biological Process (BP) negative regulation of mitotic cell cycle 0.1772 Highly Informative Inherited
Biological Process (BP) negative regulation of organelle organization 0.0114 Highly Informative Inherited
Biological Process (BP) regulation of mitotic nuclear division 0.01678 Highly Informative Inherited
Biological Process (BP) regulation of chromosome organization 0.01587 Highly Informative Inherited
Biological Process (BP) regulation of mitotic cell cycle phase transition 0.2126 Highly Informative Inherited
Biological Process (BP) negative regulation of cell cycle process 0.0791 Highly Informative Inherited
Biological Process (BP) mitotic cell cycle process 0.009395 Highly Informative Inherited
Cellular Component (CC) macromolecular complex 0.00007214 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.00004407 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.000000009256 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) envelope 0.0007457 Moderately Informative Direct
Cellular Component (CC) cytoskeleton 0.1183 Moderately Informative Inherited
Cellular Component (CC) endomembrane system 0.09108 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.001915 Moderately Informative Inherited
Cellular Component (CC) nuclear envelope 0.00001025 Informative Direct
Cellular Component (CC) microtubule cytoskeleton 0.000000007057 Informative Direct
Cellular Component (CC) chromosome 0.0121 Informative Inherited
Cellular Component (CC) cytoskeletal part 0.007576 Informative Inherited
Cellular Component (CC) kinetochore 0.00000000002276 Highly Informative Direct
Cellular Component (CC) spindle 0.00000005188 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.0000007956Least InformativeDirect
Biological processCell cycle0Moderately InformativeDirect
Biological processMitosis0InformativeDirect
Biological processMeiosis0Highly InformativeDirect
Biological processChromosome partition0.00000000000002511Highly InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Cellular componentCytoplasm0.9312Least InformativeInherited
Cellular componentCytoskeleton0Moderately InformativeDirect
Cellular componentChromosome0.000000000000009732InformativeDirect
Cellular componentCentromere0Highly InformativeDirect
DomainRepeat0Least InformativeDirect
DomainWD repeat0Highly InformativeDirect
Post-translational modificationPhosphoprotein0.0006739Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 14 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a WD40 repeat-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]