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Nqo1C-terminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Bromodomain-like [ 47363] (15)
Superfamily:   Nqo1C-terminal domain-like [ 140490]
Families:   Nqo1C-terminal domain-like [ 140491]


Superfamily statistics
Genomes (1,871) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 2,767 16,834 1
Proteins 2,765 16,790 1


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0.000000000003741 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0001339 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000004024 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.00004451 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.006151 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.002605 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.002244 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) generation of precursor metabolites and energy 0 Moderately Informative Direct
Biological Process (BP) nucleoside phosphate metabolic process 0 Moderately Informative Direct
Biological Process (BP) oxidation-reduction process 0 Moderately Informative Direct
Biological Process (BP) purine-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.00000000001916 Moderately Informative Direct
Biological Process (BP) electron transport chain 0 Informative Direct
Biological Process (BP) cellular respiration 0 Informative Direct
Biological Process (BP) ATP metabolic process 0 Informative Direct
Biological Process (BP) phosphorylation 0.002756 Informative Inherited
Biological Process (BP) mitochondrial electron transport, NADH to ubiquinone 0.000000001512 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) NADH dehydrogenase activity 0 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on hydrogen as donor 0.0000000004129 Highly Informative Direct
Cellular Component (CC) protein complex 0.1826 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.04792 Least Informative Inherited
Cellular Component (CC) membrane 0.001033 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.0283 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 0.02061 Least Informative Inherited
Cellular Component (CC) mitochondrial envelope 0.0000000000001339 Moderately Informative Direct
Cellular Component (CC) organelle inner membrane 0.000000000000005967 Moderately Informative Direct
Cellular Component (CC) membrane protein complex 0.0000000000001825 Moderately Informative Direct
Cellular Component (CC) mitochondrial protein complex 0.00000000000362 Moderately Informative Direct
Cellular Component (CC) mitochondrial respiratory chain 0.000000865 Informative Direct
Cellular Component (CC) inner mitochondrial membrane protein complex 0.0000002212 Informative Direct
Cellular Component (CC) respiratory chain complex 0 Informative Direct
Cellular Component (CC) oxidoreductase complex 0 Informative Direct
Cellular Component (CC) mitochondrial respiratory chain complex I 0.000017 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on NADH or NADPH0Moderately InformativeDirect
Enzyme Commission (EC)With other acceptors0InformativeDirect
Enzyme Commission (EC)NADH:ubiquinone reductase (H(+)-translocating)0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processTransport0.0001611Least InformativeDirect
Biological processElectron transport0.000000000007455InformativeDirect
Biological processRespiratory chain0Highly InformativeDirect
Cellular componentMembrane0.0008585Least InformativeDirect
Cellular componentMitochondrion0.00000000008508Moderately InformativeDirect
Cellular componentMitochondrion inner membrane0.00003918InformativeDirect
DomainTransit peptide0.0000000000003188Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionFlavoprotein0Moderately InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionIron-sulfur0Moderately InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular function4Fe-4S0InformativeDirect
Molecular functionFMN0.00000000000001023InformativeDirect
Molecular functionUbiquinone0Highly InformativeDirect
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationQuinone0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nqo1C-terminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Nqo1C-terminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]