SUPERFAMILY 1.75 HMM library and genome assignments server

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Dcp2 domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Dcp2 domain-like [ 140585]
Superfamily:   Dcp2 domain-like [ 140586]
Families:   Dcp2 box A domain [ 140587]


Superfamily statistics
Genomes (450) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 538 1,369 2
Proteins 537 1,368 2


Functional annotation
General category Regulation
Detailed category RNA binding, metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0.00000000006482 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.0000000002522 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.00000002531 Least Informative Direct
Biological Process (BP) primary metabolic process 0.000001062 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.00000000005606 Least Informative Direct
Biological Process (BP) biological regulation 0.0001114 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000000001655 Least Informative Direct
Biological Process (BP) negative regulation of metabolic process 0.0000000000002783 Moderately Informative Direct
Biological Process (BP) regulation of gene expression 0.0000000001717 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0.000000000000003734 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.000000000000007296 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0.00008319 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.00000000000001763 Moderately Informative Direct
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 0.00141 Moderately Informative Inherited
Biological Process (BP) negative regulation of gene expression 0.000000000000003734 Informative Direct
Biological Process (BP) nucleobase-containing compound catabolic process 0 Informative Direct
Biological Process (BP) cellular macromolecule catabolic process 0 Informative Direct
Biological Process (BP) RNA catabolic process 0 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.00000000002792 Least Informative Direct
Molecular Function (MF) binding 0.247 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.0002942 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.000000000000007039 Moderately Informative Direct
Molecular Function (MF) RNA binding 0.000001975 Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.000006025 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.01551 Least Informative Inherited
Cellular Component (CC) ribonucleoprotein granule 0 Informative Direct
Cellular Component (CC) P-body 0.0005734 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processmRNA processing0.0000000001313InformativeDirect
Biological processNonsense-mediated mRNA decay0Highly InformativeDirect
Cellular componentCytoplasm0.0000957Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationRNA-binding0.000000008666Moderately InformativeDirect
Post-translational modificationPhosphoprotein0.0001022Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Dcp2 domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the Dcp2 domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]