SUPERFAMILY 1.75 HMM library and genome assignments server

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IMD domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   BAR/IMD domain-like [ 116747]
Superfamily:   BAR/IMD domain-like [ 103657] (4)
Family:   IMD domain [ 140703]


Family statistics
Genomes (89) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 321 731 2
Proteins 321 729 2


Gene Ontology (high-coverage)

(
show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism cellular process 0.0000002178 Least Informative Direct
Biological Process (BP) biological regulation 0.00000001172 Least Informative Direct
Biological Process (BP) response to stimulus 0.005092 Least Informative Inherited
Biological Process (BP) reproduction 0.000000622 Moderately Informative Direct
Biological Process (BP) cellular component biogenesis 0.000009001 Moderately Informative Direct
Biological Process (BP) negative regulation of biological process 0.00009651 Moderately Informative Direct
Biological Process (BP) cellular developmental process 0.00000008512 Moderately Informative Direct
Biological Process (BP) multi-organism process 0.000000000006965 Moderately Informative Direct
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) response to stress 0.1984 Moderately Informative Inherited
Biological Process (BP) cellular response to stimulus 0.1044 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.001807 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 0.6555 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) response to external stimulus 0.1705 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.5689 Moderately Informative Inherited
Biological Process (BP) developmental process involved in reproduction 0.00006057 Informative Direct
Biological Process (BP) movement of cell or subcellular component 0.0001441 Informative Direct
Biological Process (BP) cytoskeleton organization 0.00003084 Informative Direct
Biological Process (BP) tissue development 0.000000004907 Informative Direct
Biological Process (BP) sexual reproduction 0.00000000001692 Informative Direct
Biological Process (BP) multicellular organism reproduction 0.00001292 Informative Direct
Biological Process (BP) locomotion 0.00000003556 Informative Direct
Biological Process (BP) regulation of cell proliferation 0.000841 Informative Direct
Biological Process (BP) single organism reproductive process 0.00002397 Informative Direct
Biological Process (BP) negative regulation of transport 0.0000000007254 Informative Direct
Biological Process (BP) actin filament-based process 0.002384 Informative Inherited
Biological Process (BP) single-organism organelle organization 0.04044 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.6347 Informative Inherited
Biological Process (BP) supramolecular fiber organization 0.002607 Informative Inherited
Biological Process (BP) response to other organism 0.6205 Informative Inherited
Biological Process (BP) regulation of anatomical structure morphogenesis 0.001277 Informative Inherited
Biological Process (BP) cell development 0.005869 Informative Inherited
Biological Process (BP) cell proliferation 0.000000006838 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0.00001958 Highly Informative Direct
Biological Process (BP) cell migration 0.000000000004108 Highly Informative Direct
Biological Process (BP) cellular process involved in reproduction in multicellular organism 0.00000001755 Highly Informative Direct
Biological Process (BP) cell projection organization 0.00000000000178 Highly Informative Direct
Biological Process (BP) epithelial cell differentiation 0 Highly Informative Direct
Biological Process (BP) tube development 0.0003655 Highly Informative Direct
Biological Process (BP) regulation of epithelial cell proliferation 0.000000000000001589 Highly Informative Direct
Biological Process (BP) regulation of vesicle-mediated transport 0.000000000004747 Highly Informative Direct
Biological Process (BP) actin filament organization 0.001651 Highly Informative Inherited
Biological Process (BP) morphogenesis of an epithelium 0.8721 Highly Informative Inherited
Biological Process (BP) regulation of cell morphogenesis 0.3114 Highly Informative Inherited
Molecular Function (MF) binding 0.000000008845 Least Informative Direct
Molecular Function (MF) anion binding 0 Moderately Informative Direct
Molecular Function (MF) protein binding 0.1426 Moderately Informative Inherited
Molecular Function (MF) lipid binding 0 Informative Direct
Molecular Function (MF) identical protein binding 0.0000000499 Informative Direct
Molecular Function (MF) protein dimerization activity 0.0000007592 Informative Direct
Molecular Function (MF) phospholipid binding 0 Highly Informative Direct
Molecular Function (MF) protein homodimerization activity 0.0007342 Highly Informative Direct
Cellular Component (CC) macromolecular complex 0.0001801 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0.00006925 Least Informative Direct
Cellular Component (CC) cytoskeleton 0.000000004129 Moderately Informative Direct
Cellular Component (CC) actin cytoskeleton 0.00000000000001923 Informative Direct
Cellular Component (CC) cell junction 0.0006962 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentCytoplasm0.04023Least InformativeInherited
Cellular componentCytoskeleton0.000000000000007806Moderately InformativeDirect
Cellular componentCell projection0.000000000002198Moderately InformativeDirect
DomainCoiled coil0.000000000002767Moderately InformativeDirect
DomainSH3 domain0InformativeDirect
Post-translational modificationActin-binding0.000000000000003376InformativeDirect
Post-translational modificationPhosphoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a BAR/IMD domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]