SUPERFAMILY 1.75 HMM library and genome assignments server

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Fic-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Fic-like [ 140930]
Superfamily:   Fic-like [ 140931]
Families:   Fic-like [ 140932] (2)

Superfamily statistics
Genomes (1,891) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 3,794 30,366 2
Proteins 3,785 30,340 2

Functional annotation
General category Metabolism
Detailed category Coenzyme metabolism and transport

Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) macromolecule metabolic process 0.00000000001984 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.000000000003577 Least Informative Direct
Biological Process (BP) primary metabolic process 0.01401 Least Informative Inherited
Biological Process (BP) cellular protein modification process 0 Moderately Informative Direct
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processVirulence0.00000002007Moderately InformativeDirect
Cellular componentMembrane0.00000000001604Least InformativeDirect
DomainRepeat0.000000000001986Least InformativeDirect
DomainTransmembrane0.0000000008338Least InformativeDirect
DomainTPR repeat0Highly InformativeDirect
Molecular functionNucleotide-binding0.000000000001809Least InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationNucleotidyltransferase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Fic-like domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Fic-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]