SUPERFAMILY 1.75 HMM library and genome assignments server

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IlvD/EDD N-terminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   IlvD/EDD N-terminal domain-like [ 143974]
Superfamily:   IlvD/EDD N-terminal domain-like [ 143975]
Families:   lvD/EDD N-terminal domain-like [ 143976]


Superfamily statistics
Genomes (2,466) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 4,428 27,878 1
Proteins 4,423 27,860 1


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) primary metabolic process 0.00000009684 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.000000000004031 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.000005659 Least Informative Direct
Biological Process (BP) biosynthetic process 0.03309 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.4532 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.0002015 Moderately Informative Direct
Biological Process (BP) cellular amino acid metabolic process 0.000000004042 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.1415 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 0.137 Moderately Informative Inherited
Biological Process (BP) monocarboxylic acid metabolic process 0.9501 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.00199 Moderately Informative Inherited
Biological Process (BP) carbohydrate catabolic process 0.00009827 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0.00002589 Informative Direct
Biological Process (BP) alpha-amino acid biosynthetic process 0.1135 Informative Inherited
Biological Process (BP) branched-chain amino acid metabolic process 0 Highly Informative Direct
Molecular Function (MF) lyase activity 0 Moderately Informative Direct
Molecular Function (MF) hydro-lyase activity 0 Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Hydro-lyases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0Moderately InformativeDirect
Biological processBranched-chain amino acid biosynthesis0Highly InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionIron0Moderately InformativeDirect
Molecular functionIron-sulfur0Moderately InformativeDirect
Molecular function4Fe-4S0InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a IlvD/EDD N-terminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 1 hidden Markov models representing the IlvD/EDD N-terminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]