SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


ZZ domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   RING/U-box [ 57849]
Superfamily:   RING/U-box [ 57850] (6)
Family:   ZZ domain [ 161211] (3)


Family statistics
Genomes (55) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 163 417 3
Proteins 163 417 3


Enzyme Commission (EC)

(
show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Histone acetyltransferase0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details) Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of limbs0.0805Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.1945Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.2138Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.3604Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.02309Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.02999Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.03382Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of body weight0.04246Moderately InformativeInherited
Phenotypic Abnormality (PA)Behavioral abnormality0.04462Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of movement0.07553Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiovascular system physiology0.1604Moderately InformativeInherited
Phenotypic Abnormality (PA)Arrhythmia0.0006664InformativeDirect
Phenotypic Abnormality (PA)Obesity0.0007081InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the palpebral fissures0.003128InformativeInherited
Phenotypic Abnormality (PA)Functional respiratory abnormality0.01893InformativeInherited
Phenotypic Abnormality (PA)Syndactyly0.0002835Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal pattern of respiration0.0002835Highly InformativeDirect
Phenotypic Abnormality (PA)Short attention span0.0003237Highly InformativeDirect
Phenotypic Abnormality (PA)Hyperactivity0.0006842Highly InformativeDirect
Phenotypic Abnormality (PA)Downslanted palpebral fissures0.0006998Highly InformativeDirect
Phenotypic Abnormality (PA)Autistic behavior0.0007081Highly InformativeDirect
Phenotypic Abnormality (PA)Clinodactyly0.0007637Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.02731Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.03409Least InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.002838Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.03277Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.1953Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular development0.1977Moderately InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.3016Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skeletal muscle morphology0.003569InformativeInherited
Mammalian Phenotype (MP)abnormal heart layer morphology0.02198InformativeInherited
Mammalian Phenotype (MP)postnatal lethality0.02549InformativeInherited
Mammalian Phenotype (MP)postnatal lethality, incomplete penetrance0.0002448Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vitelline vasculature morphology0.0003239Highly InformativeDirect
Mammalian Phenotype (MP)abnormal skeletal muscle fiber morphology0.0003503Highly InformativeDirect
Mammalian Phenotype (MP)abnormal physical strength0.003097Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)tagma0Least InformativeDirect
Fly Anatomy (FA)segment0Least InformativeDirect
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)somatic cell0.2053Least InformativeInherited
Fly Anatomy (FA)adult mesothoracic segment0.01698Moderately InformativeInherited
Fly Anatomy (FA)syncytium0.00342InformativeInherited
Fly Anatomy (FA)muscle cell0.00496InformativeInherited
Fly Anatomy (FA)flight muscle0.00005153Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot internode0Least InformativeDirect
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0Least InformativeDirect
Plant ANatomical entity (PAN)branch0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot meristem0.000002481Highly InformativeDirect
Plant ANatomical entity (PAN)apical meristem0.00003119Highly InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0.000001343InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups1InformativeInherited
Enzyme Commission (EC)Histone acetyltransferase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 38 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a RING/U-box domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]