SUPERFAMILY 1.75 HMM library and genome assignments server

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Homeodomain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   DNA/RNA-binding 3-helical bundle [ 46688] (14)
Superfamily:   Homeodomain-like [ 46689] (19)
Family:   Homeodomain [ 46690] (40)


Family statistics
Genomes (186) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,632 12,364 56
Proteins 4,623 12,337 56


Disease Ontology (DO)

(
show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)physical disorder0.0004572InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0.0005256Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the eye0.02241Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.2052Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.2423Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.4877Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.7642Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.9656Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the endocrine system0.1699Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.2707Moderately InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0.4096Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebrum0.5548Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vertebral column0.8057Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the abdominal organs0.9458Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal lip morphology0.002111InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the fontanelles or cranial sutures0.0143InformativeInherited
Phenotypic Abnormality (PA)Abnormal palate morphology0.01602InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the thyroid gland0.03356InformativeInherited
Phenotypic Abnormality (PA)Abnormal vertebral morphology0.1267InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating hormone level0.1339InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebral subcortex0.1661InformativeInherited
Phenotypic Abnormality (PA)Short stature0.4055InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anterior pituitary0.5101InformativeInherited
Phenotypic Abnormality (PA)Abnormal fundus morphology0.5434InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.5803InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia affecting the eye0.000003501Highly InformativeDirect
Phenotypic Abnormality (PA)Agenesis of corpus callosum0.0000701Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of periauricular region0.0002378Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of circulating adrenocorticotropin level0.005234Highly InformativeInherited
Phenotypic Abnormality (PA)Midline defect of the nose0.006868Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal ureter physiology0.1013Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cervical spine0.1625Highly InformativeInherited
Phenotypic Abnormality (PA)Cleft palate0.3889Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal bone structure0.7394Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000000000002344Least InformativeDirect
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.0000003679Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.000001627Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.000002356Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0.05588Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.4158Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.672Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype1Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal craniofacial morphology0.000000000000007866Moderately InformativeDirect
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.0000000000006013Moderately InformativeDirect
Mammalian Phenotype (MP)limbs/digits/tail phenotype0.00000001062Moderately InformativeDirect
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.0000004436Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.0000006204Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal head morphology0.0000008726Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0.000001773Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal digestive system morphology0.001173Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.004294Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal embryo morphology0.03994Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.0476Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.06413Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal endocrine gland morphology0.06678Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.1264Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.2913Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin adnexa morphology0.345Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.5622Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.8135Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.8368Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.959Moderately InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.9615Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle physiology1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.0000000000983InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord morphology0.00002933InformativeDirect
Mammalian Phenotype (MP)abnormal gas homeostasis0.00007528InformativeDirect
Mammalian Phenotype (MP)normal phenotype0.00007613InformativeDirect
Mammalian Phenotype (MP)postnatal lethality0.00008457InformativeDirect
Mammalian Phenotype (MP)abnormal cranial nerve morphology0.000146InformativeDirect
Mammalian Phenotype (MP)abnormal systemic artery morphology0.0005732InformativeDirect
Mammalian Phenotype (MP)abnormal neuron differentiation0.000753InformativeDirect
Mammalian Phenotype (MP)abnormal cartilage morphology0.001379InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic cage morphology0.004527InformativeInherited
Mammalian Phenotype (MP)abnormal consumption behavior0.01152InformativeInherited
Mammalian Phenotype (MP)abnormal mouth morphology0.02341InformativeInherited
Mammalian Phenotype (MP)abnormal developmental patterning0.0279InformativeInherited
Mammalian Phenotype (MP)abnormal brain development0.04718InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system tract morphology0.08176InformativeInherited
Mammalian Phenotype (MP)abnormal hearing physiology0.08446InformativeInherited
Mammalian Phenotype (MP)abnormal brain white matter morphology0.1015InformativeInherited
Mammalian Phenotype (MP)abnormal neural tube morphology0.1083InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton development0.128InformativeInherited
Mammalian Phenotype (MP)abnormal anterior eye segment morphology0.1508InformativeInherited
Mammalian Phenotype (MP)abnormal thymus morphology0.2069InformativeInherited
Mammalian Phenotype (MP)abnormal pancreas morphology0.2082InformativeInherited
Mammalian Phenotype (MP)abnormal skeletal muscle morphology0.2435InformativeInherited
Mammalian Phenotype (MP)abnormal autopod morphology0.2579InformativeInherited
Mammalian Phenotype (MP)abnormal limb bone morphology0.4029InformativeInherited
Mammalian Phenotype (MP)abnormal primary sex determination0.4896InformativeInherited
Mammalian Phenotype (MP)abnormal mammary gland morphology0.5109InformativeInherited
Mammalian Phenotype (MP)abnormal limbic system morphology0.5966InformativeInherited
Mammalian Phenotype (MP)abnormal jaw morphology0.6207InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.6371InformativeInherited
Mammalian Phenotype (MP)abnormal ovary morphology0.7668InformativeInherited
Mammalian Phenotype (MP)abnormal cerebral hemisphere morphology0.8268InformativeInherited
Mammalian Phenotype (MP)abnormal testis morphology0.8592InformativeInherited
Mammalian Phenotype (MP)abnormal metencephalon morphology0.9845InformativeInherited
Mammalian Phenotype (MP)abnormal spleen morphology1InformativeInherited
Mammalian Phenotype (MP)abnormal digestive system physiology1InformativeInherited
Mammalian Phenotype (MP)abnormal long bone morphology1InformativeInherited
Mammalian Phenotype (MP)vertebral transformation0.0000000007585Highly InformativeDirect
Mammalian Phenotype (MP)cyanosis0.000000001053Highly InformativeDirect
Mammalian Phenotype (MP)abnormal middle ear morphology0.000000006257Highly InformativeDirect
Mammalian Phenotype (MP)taste/olfaction phenotype0.0000002562Highly InformativeDirect
Mammalian Phenotype (MP)abnormal rib joint0.000002179Highly InformativeDirect
Mammalian Phenotype (MP)distended abdomen0.000003959Highly InformativeDirect
Mammalian Phenotype (MP)abnormal neuroendocrine gland morphology0.000005699Highly InformativeDirect
Mammalian Phenotype (MP)abnormal secondary palate development0.00009817Highly InformativeDirect
Mammalian Phenotype (MP)abnormal diencephalon morphology0.0001318Highly InformativeDirect
Mammalian Phenotype (MP)abnormal pancreas development0.0003502Highly InformativeDirect
Mammalian Phenotype (MP)abnormal telencephalon development0.0005401Highly InformativeDirect
Mammalian Phenotype (MP)microphthalmia0.0005833Highly InformativeDirect
Mammalian Phenotype (MP)abnormal temporal bone morphology0.0008148Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vas deferens morphology0.0008481Highly InformativeDirect
Mammalian Phenotype (MP)abnormal eye development0.00228Highly InformativeInherited
Mammalian Phenotype (MP)abnormal urinary system development0.005306Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hindbrain development0.01009Highly InformativeInherited
Mammalian Phenotype (MP)abnormal midbrain morphology0.01133Highly InformativeInherited
Mammalian Phenotype (MP)abnormal thyroid gland morphology0.01182Highly InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic aorta morphology0.01639Highly InformativeInherited
Mammalian Phenotype (MP)impaired hearing0.01972Highly InformativeInherited
Mammalian Phenotype (MP)abnormal rib morphology0.02653Highly InformativeInherited
Mammalian Phenotype (MP)abnormal sternum morphology0.03189Highly InformativeInherited
Mammalian Phenotype (MP)abnormal lens morphology0.05377Highly InformativeInherited
Mammalian Phenotype (MP)abnormal anterior uvea morphology0.06264Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hypaxial muscle morphology0.101Highly InformativeInherited
Mammalian Phenotype (MP)abnormal pancreatic beta cell morphology0.112Highly InformativeInherited
Mammalian Phenotype (MP)abnormal mandible morphology0.1739Highly InformativeInherited
Mammalian Phenotype (MP)abnormal food intake0.4466Highly InformativeInherited
Mammalian Phenotype (MP)abnormal secondary palate morphology0.538Highly InformativeInherited
Mammalian Phenotype (MP)abnormal forelimb stylopod morphology0.8535Highly InformativeInherited
Mammalian Phenotype (MP)abnormal dorsal telencephalic commissure morphology0.8827Highly InformativeInherited
Mammalian Phenotype (MP)abnormal femur morphology0.9768Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.000000002291Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.00000002243Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.0000004161Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.04193Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.3493Least InformativeInherited
Worm Phenotype (WP)larval lethal0.4093Least InformativeInherited
Worm Phenotype (WP)organism segment morphology variant0.0000000003063Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.0000000003355Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.00000003699Moderately InformativeDirect
Worm Phenotype (WP)level of transgene expression variant0.000003662Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.6731Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.6888Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.7898Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant1Moderately InformativeInherited
Worm Phenotype (WP)male morphology variant0.00000000116InformativeDirect
Worm Phenotype (WP)cell fate specification variant0.000004262InformativeDirect
Worm Phenotype (WP)locomotor coordination variant0.05564InformativeInherited
Worm Phenotype (WP)forward locomotion variant0.06644InformativeInherited
Worm Phenotype (WP)foraging behavior variant0.07457InformativeInherited
Worm Phenotype (WP)body posture variant0.1609InformativeInherited
Worm Phenotype (WP)vulva development variant0.3637InformativeInherited
Worm Phenotype (WP)locomotion reduced0.5909InformativeInherited
Worm Phenotype (WP)cell number increased1InformativeInherited
Worm Phenotype (WP)sexually dimorphic development variant0.00000109Highly InformativeDirect
Worm Phenotype (WP)lineage variant0.000003051Highly InformativeDirect
Worm Phenotype (WP)carbon dioxide avoidance variant0.00001618Highly InformativeDirect
Worm Phenotype (WP)tail morphology variant0.00003058Highly InformativeDirect
Worm Phenotype (WP)forward locomotion decreased0.00003502Highly InformativeDirect
Worm Phenotype (WP)neuronal cell fate specification variant0.0000713Highly InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.00009358Highly InformativeDirect
Worm Phenotype (WP)cell number decreased0.0001462Highly InformativeDirect
Worm Phenotype (WP)multiple anchor cells0.0001513Highly InformativeDirect
Worm Phenotype (WP)body region development variant0.0003928Highly InformativeDirect
Worm Phenotype (WP)coiling frequency variant0.0004849Highly InformativeDirect
Worm Phenotype (WP)loss of left right asymmetry0.000583Highly InformativeDirect
Worm Phenotype (WP)roaming variant0.007755Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.03517Least InformativeInherited
Fly Phenotype (FP)visible0Moderately InformativeDirect
Fly Phenotype (FP)lethal - all die before end of P-stage0.07174Moderately InformativeInherited
Fly Phenotype (FP)lethal - all die before end of first instar larval stage0.00000002072InformativeDirect
Fly Phenotype (FP)lethal - all die before end of embryonic stage0.000000001442Highly InformativeDirect
Fly Phenotype (FP)pair rule phenotype0.00000003325Highly InformativeDirect
Fly Phenotype (FP)homeotic0.00000009217Highly InformativeDirect
Fly Phenotype (FP)some die during embryonic stage0.0001315Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0.000000000001618Least InformativeDirect
Fly Anatomy (FA)tagma0.000000000007286Least InformativeDirect
Fly Anatomy (FA)adult0.0000000006763Least InformativeDirect
Fly Anatomy (FA)segment0.0000005448Least InformativeDirect
Fly Anatomy (FA)anatomical group0.0001449Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0.002455Least InformativeInherited
Fly Anatomy (FA)nervous system0.06206Least InformativeInherited
Fly Anatomy (FA)larva0.0734Least InformativeInherited
Fly Anatomy (FA)somatic cell0.1692Least InformativeInherited
Fly Anatomy (FA)larval tagma0.000000003Moderately InformativeDirect
Fly Anatomy (FA)adult integumentary system0.00000002723Moderately InformativeDirect
Fly Anatomy (FA)appendage0.00000003024Moderately InformativeDirect
Fly Anatomy (FA)multi-cell-component structure0.00000009697Moderately InformativeDirect
Fly Anatomy (FA)developing embryonic structure0.000005261Moderately InformativeDirect
Fly Anatomy (FA)ganglion0.000007096Moderately InformativeDirect
Fly Anatomy (FA)abdomen0.0001761Moderately InformativeDirect
Fly Anatomy (FA)cell cluster organ0.0008274Moderately InformativeDirect
Fly Anatomy (FA)acellular anatomical structure0.001013Moderately InformativeInherited
Fly Anatomy (FA)adult mesothoracic segment0.00157Moderately InformativeInherited
Fly Anatomy (FA)sense organ0.002988Moderately InformativeInherited
Fly Anatomy (FA)central nervous system0.01878Moderately InformativeInherited
Fly Anatomy (FA)tagmatic subdivision of integument0.0248Moderately InformativeInherited
Fly Anatomy (FA)neuron0.03034Moderately InformativeInherited
Fly Anatomy (FA)somatic precursor cell0.4735Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.7304Moderately InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.8073Moderately InformativeInherited
Fly Anatomy (FA)female organism0.8796Moderately InformativeInherited
Fly Anatomy (FA)adult head0.8836Moderately InformativeInherited
Fly Anatomy (FA)interneuron0.0000002014InformativeDirect
Fly Anatomy (FA)embryonic/larval neuron0.00006494InformativeDirect
Fly Anatomy (FA)appendage segment0.0001033InformativeDirect
Fly Anatomy (FA)primordium0.0001146InformativeDirect
Fly Anatomy (FA)extended germ band embryo0.000123InformativeDirect
Fly Anatomy (FA)mesothoracic tergum0.0001836InformativeDirect
Fly Anatomy (FA)antennal segment0.000235InformativeDirect
Fly Anatomy (FA)adult external head0.0004042InformativeDirect
Fly Anatomy (FA)segmental subdivision of organ system0.0006149InformativeDirect
Fly Anatomy (FA)larval abdominal segment0.001351InformativeInherited
Fly Anatomy (FA)syncytium0.001449InformativeInherited
Fly Anatomy (FA)muscle cell0.001963InformativeInherited
Fly Anatomy (FA)nerve0.003732InformativeInherited
Fly Anatomy (FA)ventral nerve cord0.008311InformativeInherited
Fly Anatomy (FA)dorsal closure embryo0.0108InformativeInherited
Fly Anatomy (FA)chemosensory system0.01576InformativeInherited
Fly Anatomy (FA)tract0.1068InformativeInherited
Fly Anatomy (FA)adult central nervous system0.1366InformativeInherited
Fly Anatomy (FA)somatic stem cell0.1833InformativeInherited
Fly Anatomy (FA)adult head sensillum0.193InformativeInherited
Fly Anatomy (FA)brain0.2245InformativeInherited
Fly Anatomy (FA)synaptic neuropil subdomain0.2933InformativeInherited
Fly Anatomy (FA)leg0.2953InformativeInherited
Fly Anatomy (FA)sensory organ cell0.3867InformativeInherited
Fly Anatomy (FA)embryonic/larval peripheral nervous system0.5321InformativeInherited
Fly Anatomy (FA)adult optic lobe neuron0.6436InformativeInherited
Fly Anatomy (FA)retina0.7652InformativeInherited
Fly Anatomy (FA)wing blade0.7661InformativeInherited
Fly Anatomy (FA)photoreceptor cell0.78InformativeInherited
Fly Anatomy (FA)histaminergic neuron0.8184InformativeInherited
Fly Anatomy (FA)presumptive embryonic/larval system0.8238InformativeInherited
Fly Anatomy (FA)cuticle0.8662InformativeInherited
Fly Anatomy (FA)chaeta0.8686InformativeInherited
Fly Anatomy (FA)anatomical space0.8791InformativeInherited
Fly Anatomy (FA)adult procephalic segment0.8947InformativeInherited
Fly Anatomy (FA)synaptic neuropil domain0.9395InformativeInherited
Fly Anatomy (FA)labral segment0.9493InformativeInherited
Fly Anatomy (FA)larval neuromere0.000001628Highly InformativeDirect
Fly Anatomy (FA)commissure0.000002555Highly InformativeDirect
Fly Anatomy (FA)head bristle0.00001401Highly InformativeDirect
Fly Anatomy (FA)presumptive embryonic/larval central nervous system0.00004955Highly InformativeDirect
Fly Anatomy (FA)ventral nervous system0.00006974Highly InformativeDirect
Fly Anatomy (FA)EL neuron0.00009922Highly InformativeDirect
Fly Anatomy (FA)U neuron0.0001763Highly InformativeDirect
Fly Anatomy (FA)maxillary palp olfactory receptor neuron0.000236Highly InformativeDirect
Fly Anatomy (FA)embryonic head0.0002567Highly InformativeDirect
Fly Anatomy (FA)tagmatic subdivision of organ system0.0003066Highly InformativeDirect
Fly Anatomy (FA)embryonic/larval sensillum0.0008873Highly InformativeDirect
Fly Anatomy (FA)adult antennal lobe glomerulus0.001104Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval head sense organ0.03292Highly InformativeInherited
Fly Anatomy (FA)visceral mesoderm derivative0.04738Highly InformativeInherited
Fly Anatomy (FA)extrinsic neuron0.06914Highly InformativeInherited
Fly Anatomy (FA)acute muscle0.0945Highly InformativeInherited
Fly Anatomy (FA)integumentary specialisation0.1601Highly InformativeInherited
Fly Anatomy (FA)sensory cluster0.4007Highly InformativeInherited
Fly Anatomy (FA)wing vein0.9058Highly InformativeInherited
Fly Anatomy (FA)denticle belt1Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)multi-tissue structure0.0008535Least InformativeDirect
Zebrafish Anatomy (ZA)nervous system0.1466Least InformativeInherited
Zebrafish Anatomy (ZA)cell0.1491Least InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.5188Least InformativeInherited
Zebrafish Anatomy (ZA)cavitated compound organ0.9591Least InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.0007244Moderately InformativeDirect
Zebrafish Anatomy (ZA)central nervous system0.2805Moderately InformativeInherited
Zebrafish Anatomy (ZA)diencephalon0.0001172InformativeDirect
Zebrafish Anatomy (ZA)embryonic structure0.08306InformativeInherited
Zebrafish Anatomy (ZA)digestive system0.1896InformativeInherited
Zebrafish Anatomy (ZA)pleuroperitoneal region0.9187InformativeInherited
Zebrafish Anatomy (ZA)endocrine system0.01107Highly InformativeInherited
Zebrafish Anatomy (ZA)telencephalon0.06183Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0.00000000009058Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0.0002676Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0.002835Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.3896Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system1Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk1Least InformativeInherited
Xenopus ANatomical entity (XAN)anatomical cluster1Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ1Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)embryonic structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0.006628Moderately InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.00791Moderately InformativeInherited
Xenopus ANatomical entity (XAN)brain0.1328Moderately InformativeInherited
Xenopus ANatomical entity (XAN)tail region0.7718Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0InformativeDirect
Xenopus ANatomical entity (XAN)neuroectoderm0InformativeDirect
Xenopus ANatomical entity (XAN)mesenchyme0InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0InformativeDirect
Xenopus ANatomical entity (XAN)anatomical space0InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.000000000008921InformativeDirect
Xenopus ANatomical entity (XAN)eye0.00000000001753InformativeDirect
Xenopus ANatomical entity (XAN)cardiovascular system0.00000002226InformativeDirect
Xenopus ANatomical entity (XAN)epithelium0.0000002721InformativeDirect
Xenopus ANatomical entity (XAN)surface structure0.000002978InformativeDirect
Xenopus ANatomical entity (XAN)notochord0.00004613InformativeDirect
Xenopus ANatomical entity (XAN)vestibuloauditory system0.02582InformativeInherited
Xenopus ANatomical entity (XAN)skeletal system0.04446InformativeInherited
Xenopus ANatomical entity (XAN)urinary system0.6861InformativeInherited
Xenopus ANatomical entity (XAN)tail0.9211InformativeInherited
Xenopus ANatomical entity (XAN)endocrine system1InformativeInherited
Xenopus ANatomical entity (XAN)limb1InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ1InformativeInherited
Xenopus ANatomical entity (XAN)hindbrain0Highly InformativeDirect
Xenopus ANatomical entity (XAN)chordal neural plate0Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural tube0Highly InformativeDirect
Xenopus ANatomical entity (XAN)presumptive midbrain-hindbrain boundary0Highly InformativeDirect
Xenopus ANatomical entity (XAN)forebrain0.000000000000001113Highly InformativeDirect
Xenopus ANatomical entity (XAN)midbrain0.000000000000001113Highly InformativeDirect
Xenopus ANatomical entity (XAN)anterior neural fold0.00000000000003947Highly InformativeDirect
Xenopus ANatomical entity (XAN)neuron0.0000000000005239Highly InformativeDirect
Xenopus ANatomical entity (XAN)head mesenchyme0.000000000004755Highly InformativeDirect
Xenopus ANatomical entity (XAN)cranial neural crest0.000000000007064Highly InformativeDirect
Xenopus ANatomical entity (XAN)pronephric tubule0.00000000001299Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural plate border0.000000000065Highly InformativeDirect
Xenopus ANatomical entity (XAN)anterior neural ridge0.0000000002372Highly InformativeDirect
Xenopus ANatomical entity (XAN)foregut0.0000000003608Highly InformativeDirect
Xenopus ANatomical entity (XAN)limb bud0.000000008243Highly InformativeDirect
Xenopus ANatomical entity (XAN)fin0.00000001713Highly InformativeDirect
Xenopus ANatomical entity (XAN)hindgut0.00000002133Highly InformativeDirect
Xenopus ANatomical entity (XAN)retinal inner nuclear layer0.0000004402Highly InformativeDirect
Xenopus ANatomical entity (XAN)involuted dorsal mesoderm0.0000007Highly InformativeDirect
Xenopus ANatomical entity (XAN)blastema0.000001131Highly InformativeDirect
Xenopus ANatomical entity (XAN)optic field0.000001267Highly InformativeDirect
Xenopus ANatomical entity (XAN)midbrain-hindbrain boundary0.000001713Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural groove0.000005398Highly InformativeDirect
Xenopus ANatomical entity (XAN)presomitic mesoderm0.000007725Highly InformativeDirect
Xenopus ANatomical entity (XAN)primordium0.000008028Highly InformativeDirect
Xenopus ANatomical entity (XAN)ganglion0.00003796Highly InformativeDirect
Xenopus ANatomical entity (XAN)tail bud0.00006213Highly InformativeDirect
Xenopus ANatomical entity (XAN)retinal ganglion cell layer0.0001828Highly InformativeDirect
Xenopus ANatomical entity (XAN)intersomitic region0.0006348Highly InformativeDirect
Xenopus ANatomical entity (XAN)circulatory system0.0009294Highly InformativeDirect
Xenopus ANatomical entity (XAN)archenteron0.02076Highly InformativeInherited
Xenopus ANatomical entity (XAN)olfactory system0.02933Highly InformativeInherited
Xenopus ANatomical entity (XAN)neurogenic placode0.7016Highly InformativeInherited
Xenopus ANatomical entity (XAN)pelvic appendage0.7132Highly InformativeInherited
Xenopus ANatomical entity (XAN)splanchnocranium0.8869Highly InformativeInherited
Xenopus ANatomical entity (XAN)skeletal tissue1Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage1Least InformativeInherited
Xenopus DEvelopment stage (XDE)embryonic stage0.000000000000001108Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)tailbud stage1InformativeInherited
Xenopus DEvelopment stage (XDE)adult frog stage0.0000007969Highly InformativeDirect
Xenopus DEvelopment stage (XDE)neurula stage0.00002549Highly InformativeDirect
Xenopus DEvelopment stage (XDE)premetamorphosis stage0.005134Highly InformativeInherited
Xenopus DEvelopment stage (XDE)gastrula stage0.0603Highly InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0.06058Least InformativeInherited
Plant ANatomical entity (PAN)seed0.06646Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.3056Least InformativeInherited
Plant ANatomical entity (PAN)vascular leaf0.339Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll0.6493Least InformativeInherited
Plant ANatomical entity (PAN)root1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)androecium1Least InformativeInherited
Plant ANatomical entity (PAN)gynoecium1Least InformativeInherited
Plant ANatomical entity (PAN)stalk1Least InformativeInherited
Plant ANatomical entity (PAN)sporangium1Least InformativeInherited
Plant ANatomical entity (PAN)fruit0.0000000000985InformativeDirect
Plant ANatomical entity (PAN)root tip0.00000000172InformativeDirect
Plant ANatomical entity (PAN)portion of ground tissue0.00000005718InformativeDirect
Plant ANatomical entity (PAN)vascular system0.00004436InformativeDirect
Plant ANatomical entity (PAN)shoot meristem0Highly InformativeDirect
Plant ANatomical entity (PAN)apical meristem0Highly InformativeDirect
Plant ANatomical entity (PAN)vegetative shoot apex0.0000000000005581Highly InformativeDirect
Plant ANatomical entity (PAN)phyllome primordium0.00000000001989Highly InformativeDirect
Plant ANatomical entity (PAN)plant ovule0.0000000001787Highly InformativeDirect
Plant ANatomical entity (PAN)primary root0.000000009909Highly InformativeDirect
Plant ANatomical entity (PAN)plant axis elongation zone0.0000008839Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0002885Highly InformativeDirect
Plant ANatomical entity (PAN)trichome0.000415Highly InformativeDirect
Plant ANatomical entity (PAN)stele0.001098Highly InformativeInherited
Plant ANatomical entity (PAN)cortex0.291Highly InformativeInherited
Plant structure DEvelopment stage (PDE)seedling development stage0.000003301InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0InformativeDirect

Document: EC annotation of SCOP domains

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Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 187 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Homeodomain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]