SUPERFAMILY 1.75 HMM library and genome assignments server

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Transducin (alpha subunit), insertion domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Transducin (alpha subunit), insertion domain [ 47894]
Superfamily:   Transducin (alpha subunit), insertion domain [ 47895]
Family:   Transducin (alpha subunit), insertion domain [ 47896]


Family statistics
Genomes (295) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,958 5,681 25
Proteins 1,955 5,673 25


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.5055Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal peripheral nervous system morphology0.07655Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebrum0.3437Moderately InformativeInherited
Phenotypic Abnormality (PA)Peripheral neuropathy0.3375InformativeInherited
Phenotypic Abnormality (PA)Paresthesia0.0009306Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.04039Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.05657Least InformativeInherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.06001Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.07071Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.1428Least InformativeInherited
Mammalian Phenotype (MP)growth/size/body region phenotype0.2842Least InformativeInherited
Mammalian Phenotype (MP)abnormal endocrine gland morphology0.0008246Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal muscle physiology0.01996Moderately InformativeInherited
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.07799Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.0946Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.1293Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal head morphology0.1792Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0.181Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal craniofacial morphology0.2109Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.2358Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood coagulation0.000925InformativeDirect
Mammalian Phenotype (MP)abnormal systemic arterial blood pressure0.001117InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.001848InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic cage morphology0.01135InformativeInherited
Mammalian Phenotype (MP)abnormal sensory capabilities/reflexes/nociception0.01812InformativeInherited
Mammalian Phenotype (MP)abnormal eye physiology0.03405InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel physiology0.06341InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.107InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.3674InformativeInherited
Mammalian Phenotype (MP)decreased systemic arterial blood pressure0.000001162Highly InformativeDirect
Mammalian Phenotype (MP)decreased platelet aggregation0.000002704Highly InformativeDirect
Mammalian Phenotype (MP)vertebral fusion0.00003339Highly InformativeDirect
Mammalian Phenotype (MP)increased interleukin-2 secretion0.00005639Highly InformativeDirect
Mammalian Phenotype (MP)abnormal rib morphology0.0001566Highly InformativeDirect
Mammalian Phenotype (MP)abnormal calcium ion homeostasis0.000832Highly InformativeDirect
Mammalian Phenotype (MP)abnormal eye electrophysiology0.002974Highly InformativeInherited
Mammalian Phenotype (MP)abnormal rib joint0.01659Highly InformativeInherited
Mammalian Phenotype (MP)abnormal mineral level0.02158Highly InformativeInherited
Mammalian Phenotype (MP)abnormal tumor necrosis factor secretion0.1282Highly InformativeInherited
Mammalian Phenotype (MP)abnormal sternum morphology0.2662Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)slow growth0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)progeny variant0Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.00000000002413Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.00000000004087Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.1531Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.6225Least InformativeInherited
Worm Phenotype (WP)movement variant6.263e-16Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.000000000000005004Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.000000000000005317Moderately InformativeDirect
Worm Phenotype (WP)chemical response variant0.00001676Moderately InformativeDirect
Worm Phenotype (WP)protein expression variant0.1374Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.2522Moderately InformativeInherited
Worm Phenotype (WP)body posture variant0InformativeDirect
Worm Phenotype (WP)foraging behavior variant0InformativeDirect
Worm Phenotype (WP)head movement variant0InformativeDirect
Worm Phenotype (WP)tail bend angle variant0InformativeDirect
Worm Phenotype (WP)locomotor coordination variant0.000000000001882InformativeDirect
Worm Phenotype (WP)forward locomotion variant0.00000000001355InformativeDirect
Worm Phenotype (WP)chemosensory response variant0.00000003317InformativeDirect
Worm Phenotype (WP)velocity of movement variant0.0000003012InformativeDirect
Worm Phenotype (WP)sensillum morphology variant0.001285InformativeInherited
Worm Phenotype (WP)nervous system physiology variant0.002098InformativeInherited
Worm Phenotype (WP)protein metabolism variant0.07986InformativeInherited
Worm Phenotype (WP)locomotion reduced0.9878InformativeInherited
Worm Phenotype (WP)acetylcholinesterase inhibitor response variant0.9926InformativeInherited
Worm Phenotype (WP)drug hypersensitive0.9985InformativeInherited
Worm Phenotype (WP)small1InformativeInherited
Worm Phenotype (WP)chemical hypersensitive1InformativeInherited
Worm Phenotype (WP)male mating variant0Highly InformativeDirect
Worm Phenotype (WP)carbon dioxide avoidance variant0Highly InformativeDirect
Worm Phenotype (WP)coiling frequency variant0Highly InformativeDirect
Worm Phenotype (WP)dye filling defect0Highly InformativeDirect
Worm Phenotype (WP)amplitude of sinusoidal movement variant0Highly InformativeDirect
Worm Phenotype (WP)fat0.00000000004555Highly InformativeDirect
Worm Phenotype (WP)roaming variant0.0000000002399Highly InformativeDirect
Worm Phenotype (WP)foraging hyperactive0.0000000004779Highly InformativeDirect
Worm Phenotype (WP)drug induced gene expression variant0.000000002776Highly InformativeDirect
Worm Phenotype (WP)pausing variant0.0000001787Highly InformativeDirect
Worm Phenotype (WP)neuron physiology variant0.00005506Highly InformativeDirect
Worm Phenotype (WP)short0.00005944Highly InformativeDirect
Worm Phenotype (WP)electrophysiology variant0.00008259Highly InformativeDirect
Worm Phenotype (WP)path curvature variant0.0002561Highly InformativeDirect
Worm Phenotype (WP)protein phosphorylation variant0.0003222Highly InformativeDirect
Worm Phenotype (WP)backward point velocity variant0.4002Highly InformativeInherited
Worm Phenotype (WP)forward point velocity variant0.7898Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

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FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)wild-type0.0004913InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect
Fly Anatomy (FA)nervous system0.08479Least InformativeInherited
Fly Anatomy (FA)somatic cell0.1493Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.1721Least InformativeInherited
Fly Anatomy (FA)anatomical group0.2676Least InformativeInherited
Fly Anatomy (FA)adult0.474Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.08369Moderately InformativeInherited
Fly Anatomy (FA)neuron0.1937Moderately InformativeInherited
Fly Anatomy (FA)chemosensory system0.00007518InformativeDirect
Fly Anatomy (FA)sensory organ cell0.06758InformativeInherited

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.005458Least InformativeInherited
Xenopus ANatomical entity (XAN)nervous system0.0655Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.2435Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0.0001261Moderately InformativeDirect
Xenopus ANatomical entity (XAN)embryonic structure0.09902Moderately InformativeInherited
Xenopus ANatomical entity (XAN)anatomical space0.0000000000008666InformativeDirect
Xenopus ANatomical entity (XAN)urinary system0.000001997InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0.0000189InformativeDirect
Xenopus ANatomical entity (XAN)animal hemisphere0.00003746InformativeDirect
Xenopus ANatomical entity (XAN)epithelium0.01825InformativeInherited
Xenopus ANatomical entity (XAN)neuron0.001367Highly InformativeInherited
Xenopus ANatomical entity (XAN)olfactory system0.113Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

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AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot internode0Least InformativeDirect
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0Least InformativeDirect
Plant ANatomical entity (PAN)branch0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant ANatomical entity (PAN)microgametophyte0Least InformativeDirect
Plant ANatomical entity (PAN)rosette leaf0.000002455InformativeDirect
Plant ANatomical entity (PAN)vascular system0.0000107InformativeDirect
Plant ANatomical entity (PAN)fruit0.00001436InformativeDirect
Plant ANatomical entity (PAN)shoot system vascular system0.00000008691Highly InformativeDirect
Plant ANatomical entity (PAN)stele0.0000002431Highly InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Transducin (alpha subunit), insertion domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]