SUPERFAMILY 1.75 HMM library and genome assignments server

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Transducin (alpha subunit), insertion domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Transducin (alpha subunit), insertion domain [ 47894]
Superfamily:   Transducin (alpha subunit), insertion domain [ 47895]
Family:   Transducin (alpha subunit), insertion domain [ 47896]


Family statistics
Genomes (295) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,958 5,681 25
Proteins 1,955 5,673 25


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.5109Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal peripheral nervous system morphology0.07617Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of forebrain morphology0.3479Moderately InformativeInherited
Phenotypic Abnormality (PA)Peripheral neuropathy0.3307InformativeInherited
Phenotypic Abnormality (PA)Paresthesia0.0008504Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

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MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.04029Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.05647Least InformativeInherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.06003Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.07062Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.1425Least InformativeInherited
Mammalian Phenotype (MP)growth/size/body region phenotype0.2843Least InformativeInherited
Mammalian Phenotype (MP)abnormal endocrine gland morphology0.000825Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal muscle physiology0.01996Moderately InformativeInherited
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.07798Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.09491Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.129Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal head morphology0.1791Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0.1811Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal craniofacial morphology0.2109Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.2353Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood coagulation0.0009252InformativeDirect
Mammalian Phenotype (MP)abnormal systemic arterial blood pressure0.001116InformativeInherited
Mammalian Phenotype (MP)impaired muscle contractility0.001848InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic cage morphology0.01126InformativeInherited
Mammalian Phenotype (MP)abnormal sensory capabilities/reflexes/nociception0.01814InformativeInherited
Mammalian Phenotype (MP)abnormal eye physiology0.03403InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel physiology0.06338InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.107InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.3685InformativeInherited
Mammalian Phenotype (MP)decreased systemic arterial blood pressure0.000001164Highly InformativeDirect
Mammalian Phenotype (MP)decreased platelet aggregation0.000002707Highly InformativeDirect
Mammalian Phenotype (MP)vertebral fusion0.00003344Highly InformativeDirect
Mammalian Phenotype (MP)increased interleukin-2 secretion0.00005644Highly InformativeDirect
Mammalian Phenotype (MP)abnormal rib morphology0.0001536Highly InformativeDirect
Mammalian Phenotype (MP)abnormal calcium ion homeostasis0.0008322Highly InformativeDirect
Mammalian Phenotype (MP)abnormal eye electrophysiology0.002972Highly InformativeInherited
Mammalian Phenotype (MP)abnormal rib joint0.01671Highly InformativeInherited
Mammalian Phenotype (MP)abnormal mineral level0.02159Highly InformativeInherited
Mammalian Phenotype (MP)abnormal tumor necrosis factor secretion0.1281Highly InformativeInherited
Mammalian Phenotype (MP)abnormal sternum morphology0.2679Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)slow growth0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)sterile progeny0Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.00000000008992Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.1218Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.5285Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.6435Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.6435Least InformativeInherited
Worm Phenotype (WP)movement variant0Moderately InformativeDirect
Worm Phenotype (WP)locomotion variant0.00000000000006433Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.0000000000001891Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.0000000000001891Moderately InformativeDirect
Worm Phenotype (WP)developmental morphology variant0.0000000000001925Moderately InformativeDirect
Worm Phenotype (WP)adult body morphology variant0.0000000000001959Moderately InformativeDirect
Worm Phenotype (WP)body morphology variant0.0000000000002529Moderately InformativeDirect
Worm Phenotype (WP)chemical response variant0.004135Moderately InformativeInherited
Worm Phenotype (WP)protein expression variant0.156Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.2232Moderately InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.232Moderately InformativeInherited
Worm Phenotype (WP)body posture variant0InformativeDirect
Worm Phenotype (WP)foraging behavior variant0InformativeDirect
Worm Phenotype (WP)head movement variant0InformativeDirect
Worm Phenotype (WP)body bend variant0InformativeDirect
Worm Phenotype (WP)tail bend angle variant0InformativeDirect
Worm Phenotype (WP)forward locomotion variant0.0000000000003346InformativeDirect
Worm Phenotype (WP)chemotaxis variant0.00000000002674InformativeDirect
Worm Phenotype (WP)velocity of movement variant0.0000003673InformativeDirect
Worm Phenotype (WP)directionality variant0.00007834InformativeDirect
Worm Phenotype (WP)acetylcholinesterase inhibitor response variant0.001496InformativeInherited
Worm Phenotype (WP)sensillum morphology variant0.001569InformativeInherited
Worm Phenotype (WP)drug hypersensitive0.02101InformativeInherited
Worm Phenotype (WP)protein metabolism variant0.06194InformativeInherited
Worm Phenotype (WP)locomotion reduced0.9897InformativeInherited
Worm Phenotype (WP)small1InformativeInherited
Worm Phenotype (WP)amphid phasmid morphology variant0Highly InformativeDirect
Worm Phenotype (WP)male mating variant0Highly InformativeDirect
Worm Phenotype (WP)carbon dioxide avoidance variant0Highly InformativeDirect
Worm Phenotype (WP)coiling frequency0Highly InformativeDirect
Worm Phenotype (WP)amplitude of sinusoidal movement variant0Highly InformativeDirect
Worm Phenotype (WP)fat0.00000000004943Highly InformativeDirect
Worm Phenotype (WP)roaming variant0.0000000004105Highly InformativeDirect
Worm Phenotype (WP)foraging hyperactive0.0000000006244Highly InformativeDirect
Worm Phenotype (WP)drug induced gene expression variant0.000000002787Highly InformativeDirect
Worm Phenotype (WP)pausing variant0.0000002414Highly InformativeDirect
Worm Phenotype (WP)short0.00005521Highly InformativeDirect
Worm Phenotype (WP)electrophysiology variant0.00007612Highly InformativeDirect
Worm Phenotype (WP)neuron physiology variant0.0001003Highly InformativeDirect
Worm Phenotype (WP)protein phosphorylation variant0.0003113Highly InformativeDirect
Worm Phenotype (WP)path curvature variant0.000313Highly InformativeDirect
Worm Phenotype (WP)cytoskeleton organization biogenesis variant0.0004347Highly InformativeDirect
Worm Phenotype (WP)backward point velocity variant0.4496Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

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FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)wild-type0.0005InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect
Fly Anatomy (FA)nervous system0.09938Least InformativeInherited
Fly Anatomy (FA)somatic cell0.1629Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.1918Least InformativeInherited
Fly Anatomy (FA)anatomical group0.2837Least InformativeInherited
Fly Anatomy (FA)adult0.5149Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.08324Moderately InformativeInherited
Fly Anatomy (FA)neuron0.195Moderately InformativeInherited
Fly Anatomy (FA)chemosensory system0.00007633InformativeDirect
Fly Anatomy (FA)sensory organ cell0.06887InformativeInherited

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.005495Least InformativeInherited
Xenopus ANatomical entity (XAN)nervous system0.06318Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.2437Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0.00009098Moderately InformativeDirect
Xenopus ANatomical entity (XAN)embryonic structure0.09942Moderately InformativeInherited
Xenopus ANatomical entity (XAN)anatomical space0.0000000000008438InformativeDirect
Xenopus ANatomical entity (XAN)urinary system0.000001996InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0.0000192InformativeDirect
Xenopus ANatomical entity (XAN)animal hemisphere0.00003883InformativeDirect
Xenopus ANatomical entity (XAN)epithelium0.01806InformativeInherited
Xenopus ANatomical entity (XAN)neuron0.001386Highly InformativeInherited
Xenopus ANatomical entity (XAN)olfactory system0.1205Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

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AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot internode0Least InformativeDirect
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0Least InformativeDirect
Plant ANatomical entity (PAN)branch0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant ANatomical entity (PAN)microgametophyte0Least InformativeDirect
Plant ANatomical entity (PAN)rosette leaf0.000002455InformativeDirect
Plant ANatomical entity (PAN)vascular system0.0000107InformativeDirect
Plant ANatomical entity (PAN)fruit0.00001436InformativeDirect
Plant ANatomical entity (PAN)shoot system vascular system0.00000008691Highly InformativeDirect
Plant ANatomical entity (PAN)stele0.0000002431Highly InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.12 twelve leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.02 two leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 6 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Transducin (alpha subunit), insertion domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]