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DNA polymerase III clamp loader subunits, C-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   post-AAA+ oligomerization domain-like [ 48018]
Superfamily:   post-AAA+ oligomerization domain-like [ 48019] (2)
Family:   DNA polymerase III clamp loader subunits, C-terminal domain [ 48020] (9)


Family statistics
Genomes (655) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,256 4,347 11
Proteins 1,256 4,346 11


Gene Ontology (high-coverage)

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show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) macromolecule metabolic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) response to stimulus 0.8156 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) nucleic acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) response to stress 0.00007718 Moderately Informative Direct
Biological Process (BP) regulation of molecular function 0.0001572 Moderately Informative Direct
Biological Process (BP) organelle organization 0.0004103 Moderately Informative Direct
Biological Process (BP) regulation of biosynthetic process 0.005538 Moderately Informative Inherited
Biological Process (BP) regulation of cellular metabolic process 0.07153 Moderately Informative Inherited
Biological Process (BP) regulation of primary metabolic process 0.06013 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 0.04532 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule metabolic process 0.07298 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.3116 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular nitrogen compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of cellular process 0.04833 Moderately Informative Inherited
Biological Process (BP) system development 0.8242 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 0.6739 Moderately Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stimulus 0.07082 Moderately Informative Inherited
Biological Process (BP) DNA metabolic process 0 Informative Direct
Biological Process (BP) cellular response to DNA damage stimulus 0 Informative Direct
Biological Process (BP) cell cycle 0.00000000002497 Informative Direct
Biological Process (BP) single-organism organelle organization 0.00000009816 Informative Direct
Biological Process (BP) chromosome organization 0.0000006233 Informative Direct
Biological Process (BP) positive regulation of molecular function 0.000001739 Informative Direct
Biological Process (BP) positive regulation of nucleobase-containing compound metabolic process 0.000005276 Informative Direct
Biological Process (BP) positive regulation of cellular biosynthetic process 0.00000951 Informative Direct
Biological Process (BP) cellular homeostasis 0.001859 Informative Inherited
Biological Process (BP) response to radiation 0.00348 Informative Inherited
Biological Process (BP) DNA replication 0 Highly Informative Direct
Biological Process (BP) regulation of DNA metabolic process 0.000000000009716 Highly Informative Direct
Biological Process (BP) chromosome segregation 0.00000000007748 Highly Informative Direct
Biological Process (BP) positive regulation of transferase activity 0.00000000008888 Highly Informative Direct
Biological Process (BP) camera-type eye development 0.0000008492 Highly Informative Direct
Biological Process (BP) response to UV 0.000001695 Highly Informative Direct
Biological Process (BP) anatomical structure homeostasis 0.00003716 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0.00001718 Least Informative Direct
Molecular Function (MF) transferase activity 0.7702 Least Informative Inherited
Molecular Function (MF) binding 0.002034 Least Informative Inherited
Molecular Function (MF) heterocyclic compound binding 0.000000000009183 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 0.00000000001711 Moderately Informative Direct
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0.00006083 Moderately Informative Direct
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) DNA binding 0 Informative Direct
Molecular Function (MF) nucleotidyltransferase activity 0.00000000000001221 Informative Direct
Cellular Component (CC) macromolecular complex 0 Least Informative Direct
Cellular Component (CC) non-membrane-bounded organelle 0 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.0000006076 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) catalytic complex 0.4959 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.09198 Moderately Informative Inherited
Cellular Component (CC) nuclear part 0.2778 Moderately Informative Inherited
Cellular Component (CC) transferase complex, transferring phosphorus-containing groups 0 Informative Direct
Cellular Component (CC) chromosome 0 Informative Direct
Cellular Component (CC) DNA polymerase complex 0 Highly Informative Direct
Cellular Component (CC) replication fork 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)DNA-directed DNA polymerase0InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processDNA replication0InformativeDirect
Cellular componentNucleus0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Post-translational modificationTransferase0.874Least InformativeInherited
Post-translational modificationDNA-binding0.00000001413Moderately InformativeDirect
Post-translational modificationNucleotidyltransferase0.000000002216InformativeDirect
Post-translational modificationDNA-directed DNA polymerase0Highly InformativeDirect
Post-translational modificationAcetylation0.0001028Least InformativeDirect
Post-translational modificationAutocatalytic cleavage0.0000002294InformativeDirect
Post-translational modificationProtein splicing0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 13 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a post-AAA+ oligomerization domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]