SUPERFAMILY 1.75 HMM library and genome assignments server

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Regulator of G-protein signaling, RGS family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Regulator of G-protein signaling, RGS [ 48096]
Superfamily:   Regulator of G-protein signaling, RGS [ 48097]
Family:   Regulator of G-protein signaling, RGS [ 48098] (9)


Family statistics
Genomes (145) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,647 7,329 11
Proteins 2,645 7,318 11


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cardiovascular system phenotype0.02964Least InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.4893Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye physiology0.0697InformativeInherited
Mammalian Phenotype (MP)enlarged pericardium0.0007754Highly InformativeDirect
Mammalian Phenotype (MP)abnormal eye electrophysiology0.004334Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.2143Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.2376Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.1213Moderately InformativeInherited
Worm Phenotype (WP)chemosensory response variant0.003166InformativeInherited
Worm Phenotype (WP)negative chemotaxis variant0.0000112Highly InformativeDirect
Worm Phenotype (WP)mechanosensation variant0.00002214Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)development0Moderately InformativeDirect
Yeast Phenotype (YP)sexual cycle0InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)viable0Least InformativeDirect
Fly Phenotype (FP)cell cycle defective0.005048InformativeInherited
Fly Phenotype (FP)mitotic cell cycle defective0.0009205Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0.6524Least InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.02687Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval cuticle0.001288Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 25 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Regulator of G-protein signaling, RGS domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]