SUPERFAMILY 1.75 HMM library and genome assignments server

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Immunoglobulin superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Immunoglobulin-like beta-sandwich [ 48725] (28)
Superfamily:   Immunoglobulin [ 48726] (4)
Families:   V set domains (antibody variable domain-like) [ 48727] (32)
  C1 set domains (antibody constant domain-like) [ 48942] (23)
  C2 set domains [ 49142] (8)
  I set domains [ 49159] (38)


Superfamily statistics
Genomes (301) Uniprot 2014_06 PDB chains (SCOP 1.75)
Domains 167,830 193,084 2,226
Proteins 60,571 85,490 1,346


Functional annotation
General category Processes_EC
Detailed category Cell adhesion

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)response to stimulus00Least InformativeDirect
Biological Process (BP)single-organism cellular process00Least InformativeDirect
Biological Process (BP)protein metabolic process00Least InformativeDirect
Biological Process (BP)localization00Least InformativeDirect
Biological Process (BP)regulation of metabolic process11Least InformativeInherited
Biological Process (BP)cellular component organization or biogenesis0.81290Least InformativeInherited
Biological Process (BP)regulation of cellular process0.000008070.4894Least InformativeInherited
Biological Process (BP)developmental process0.21490Least InformativeInherited
Biological Process (BP)multicellular organismal process0.24280Least InformativeInherited
Biological Process (BP)positive regulation of response to stimulus00Moderately InformativeDirect
Biological Process (BP)signal transduction00Moderately InformativeDirect
Biological Process (BP)immune system process00Moderately InformativeDirect
Biological Process (BP)regulation of protein metabolic process0.00000038240.0000000000002123Moderately InformativeDirect
Biological Process (BP)nervous system development0.00009150Moderately InformativeDirect
Biological Process (BP)anatomical structure morphogenesis0.00043080Moderately InformativeDirect
Biological Process (BP)regulation of multicellular organismal process10Moderately InformativeInherited
Biological Process (BP)regulation of catalytic activity0.000093010.5343Moderately InformativeInherited
Biological Process (BP)positive regulation of metabolic process11Moderately InformativeInherited
Biological Process (BP)positive regulation of molecular function0.00000055790.1087Moderately InformativeInherited
Biological Process (BP)regulation of developmental process10Moderately InformativeInherited
Biological Process (BP)regulation of cellular component organization0.84850Moderately InformativeInherited
Biological Process (BP)negative regulation of cellular process11Moderately InformativeInherited
Biological Process (BP)regulation of signal transduction11Moderately InformativeInherited
Biological Process (BP)response to organic substance0.55780.004029Moderately InformativeInherited
Biological Process (BP)response to endogenous stimulus11Moderately InformativeInherited
Biological Process (BP)cellular response to chemical stimulus10.2193Moderately InformativeInherited
Biological Process (BP)regulation of phosphate metabolic process10.000000000547Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.36081Moderately InformativeInherited
Biological Process (BP)cell differentiation0.73960.0000002116Moderately InformativeInherited
Biological Process (BP)positive regulation of cellular process10.9384Moderately InformativeInherited
Biological Process (BP)regulation of localization10.271Moderately InformativeInherited
Biological Process (BP)multi-organism process0.023830Moderately InformativeInherited
Biological Process (BP)organ development0.064190.000000002365Moderately InformativeInherited
Biological Process (BP)single-organism developmental process10Moderately InformativeInherited
Biological Process (BP)vesicle-mediated transport00InformativeDirect
Biological Process (BP)regulation of immune response00InformativeDirect
Biological Process (BP)immune response00InformativeDirect
Biological Process (BP)positive regulation of immune system process00InformativeDirect
Biological Process (BP)defense response00InformativeDirect
Biological Process (BP)immune effector process00.00000000000002112InformativeDirect
Biological Process (BP)biological adhesion0.000000000000015540InformativeDirect
Biological Process (BP)regulation of protein phosphorylation0.0000000000014820.00000003414InformativeDirect
Biological Process (BP)generation of neurons0.000000000067850InformativeDirect
Biological Process (BP)sensory organ development0.00000018240.00000000002676InformativeDirect
Biological Process (BP)regulation of nervous system development0.00000038330.00000007316InformativeDirect
Biological Process (BP)negative regulation of cellular component organization0.0000044050.0004106InformativeDirect
Biological Process (BP)anatomical structure formation involved in morphogenesis0.000030660.00000005924InformativeDirect
Biological Process (BP)cardiovascular system development0.000035990.00000003277InformativeDirect
Biological Process (BP)positive regulation of phosphate metabolic process0.099210.0000000001913InformativeInherited
Biological Process (BP)positive regulation of protein modification process0.74640.0000001292InformativeInherited
Biological Process (BP)regulation of kinase activity0.0010081InformativeInherited
Biological Process (BP)regulation of cell proliferation10InformativeInherited
Biological Process (BP)regulation of ion transport0.082120.624InformativeInherited
Biological Process (BP)regulation of cellular component movement0.39360.00000000221InformativeInherited
Biological Process (BP)regulation of response to external stimulus11InformativeInherited
Biological Process (BP)regulation of locomotion0.11990.000000000003761InformativeInherited
Biological Process (BP)negative regulation of signaling0.00019460.06036InformativeInherited
Biological Process (BP)negative regulation of cell communication0.00069420.1573InformativeInherited
Biological Process (BP)negative regulation of response to stimulus11InformativeInherited
Biological Process (BP)organ morphogenesis0.000038130.001391InformativeInherited
Biological Process (BP)cellular response to endogenous stimulus0.16910InformativeInherited
Biological Process (BP)positive regulation of signal transduction10.9472InformativeInherited
Biological Process (BP)regulation of intracellular protein kinase cascade0.15040.0000005417InformativeInherited
Biological Process (BP)regulation of cell development0.00017590.01005InformativeInherited
Biological Process (BP)regulation of anatomical structure morphogenesis0.0031430.000000000007167InformativeInherited
Biological Process (BP)positive regulation of transport0.97880.7412InformativeInherited
Biological Process (BP)regulation of intracellular transport0.022341InformativeInherited
Biological Process (BP)response to other organism0.0049230.000000000002874InformativeInherited
Biological Process (BP)enzyme linked receptor protein signaling pathway11InformativeInherited
Biological Process (BP)regulation of immune effector process11InformativeInherited
Biological Process (BP)phagocytosis00Highly InformativeDirect
Biological Process (BP)leukocyte mediated immunity00Highly InformativeDirect
Biological Process (BP)humoral immune response00Highly InformativeDirect
Biological Process (BP)immune response-regulating cell surface receptor signaling pathway00Highly InformativeDirect
Biological Process (BP)positive regulation of cell activation00Highly InformativeDirect
Biological Process (BP)protein activation cascade00Highly InformativeDirect
Biological Process (BP)innate immune response00.0000000001065Highly InformativeDirect
Biological Process (BP)positive regulation of peptidyl-tyrosine phosphorylation0.000000000000050670.0000000002417Highly InformativeDirect
Biological Process (BP)negative regulation of cellular component movement0.00000000030190.0000161Highly InformativeDirect
Biological Process (BP)angiogenesis0.00000000051120Highly InformativeDirect
Biological Process (BP)negative regulation of locomotion0.0000000014050.000004409Highly InformativeDirect
Biological Process (BP)regulation of mononuclear cell proliferation0.0000000021240Highly InformativeDirect
Biological Process (BP)positive regulation of MAPK cascade0.0000000047520Highly InformativeDirect
Biological Process (BP)immune response-activating signal transduction0.000000047170.00001464Highly InformativeDirect
Biological Process (BP)cell adhesion0.0000018860Highly InformativeDirect
Biological Process (BP)cell junction organization0.000010140.00000000006734Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte proliferation0.000052750.0000002628Highly InformativeDirect
Biological Process (BP)transmembrane receptor protein tyrosine kinase signaling pathway0.0001310Highly InformativeDirect
Biological Process (BP)cellular response to growth factor stimulus0.00020960.00000000000005413Highly InformativeDirect
Biological Process (BP)regulation of leukocyte mediated cytotoxicity0.00024430.00000000003308Highly InformativeDirect
Biological Process (BP)regulation of cell morphogenesis involved in differentiation0.00033190.000000000001527Highly InformativeDirect
Biological Process (BP)positive regulation of leukocyte mediated immunity0.00055490.000000000004037Highly InformativeDirect
Biological Process (BP)positive regulation of protein kinase activity0.54931Highly InformativeInherited
Biological Process (BP)eye morphogenesis0.0000000081060.001256Highly InformativeInherited
Biological Process (BP)positive regulation of response to external stimulus11Highly InformativeInherited
Biological Process (BP)regulation of behavior11Highly InformativeInherited
Biological Process (BP)negative regulation of immune system process0.7110Highly InformativeInherited
Biological Process (BP)retina development in camera-type eye0.0000000027990.007628Highly InformativeInherited
Biological Process (BP)positive regulation of ion transport0.00046020.0623Highly InformativeInherited
Biological Process (BP)positive regulation of intracellular transport0.0037360.2364Highly InformativeInherited
Biological Process (BP)positive regulation of homeostatic process0.0043620.237Highly InformativeInherited
Biological Process (BP)regulation of calcium ion transport0.00000000056710.1252Highly InformativeInherited
Biological Process (BP)regulation of ion homeostasis0.0000000038550.3246Highly InformativeInherited
Biological Process (BP)positive regulation of adaptive immune response10.000001777Highly InformativeInherited
Biological Process (BP)regulation of adaptive immune response based on somatic recombination of immune receptors built from0.0021470Highly InformativeInherited
Biological Process (BP)regulation of lymphocyte mediated immunity0.003960.0003358Highly InformativeInherited
Biological Process (BP)positive regulation of cell killing0.39650Highly InformativeInherited
Molecular Function (MF)binding00Least InformativeDirect
Molecular Function (MF)transferase activity10.01515Least InformativeInherited
Molecular Function (MF)anion binding0.051371Moderately InformativeInherited
Molecular Function (MF)structural molecule activity0.19360Moderately InformativeInherited
Molecular Function (MF)enzyme regulator activity0.024641Moderately InformativeInherited
Molecular Function (MF)transferase activity, transferring phosphorus-containing groups0.10990Moderately InformativeInherited
Molecular Function (MF)receptor activity0.000011980InformativeDirect
Molecular Function (MF)molecular transducer activity0.00013230InformativeDirect
Molecular Function (MF)amide binding0.00086050InformativeDirect
Molecular Function (MF)lipid binding0.22761InformativeInherited
Molecular Function (MF)receptor binding0.001010.002039InformativeInherited
Molecular Function (MF)GTPase regulator activity0.000000023040.9239InformativeInherited
Molecular Function (MF)enzyme activator activity0.000000440.94InformativeInherited
Molecular Function (MF)phosphotransferase activity, alcohol group as acceptor0.0052740InformativeInherited
Molecular Function (MF)kinase activity0.035990InformativeInherited
Molecular Function (MF)antigen binding00Highly InformativeDirect
Molecular Function (MF)glycolipid binding0.0000000000000019880.000000003692Highly InformativeDirect
Molecular Function (MF)peptide binding0.0000001350Highly InformativeDirect
Molecular Function (MF)protein kinase activity0.00054650Highly InformativeDirect
Molecular Function (MF)phosphatidylinositol binding0.0000000000017380.3133Highly InformativeInherited
Molecular Function (MF)GTPase activator activity0.00000000000046650.2735Highly InformativeInherited
Molecular Function (MF)small GTPase regulator activity0.00000000000290.3451Highly InformativeInherited
Cellular Component (CC)membrane00Least InformativeDirect
Cellular Component (CC)protein complex0.73520.1177Least InformativeInherited
Cellular Component (CC)plasma membrane00Moderately InformativeDirect
Cellular Component (CC)vesicle00Moderately InformativeDirect
Cellular Component (CC)extracellular region part00Moderately InformativeDirect
Cellular Component (CC)cell projection0.053920Moderately InformativeInherited
Cellular Component (CC)extracellular membrane-bounded organelle00InformativeDirect
Cellular Component (CC)cell surface00InformativeDirect
Cellular Component (CC)neuron projection0.000000000027540InformativeDirect
Cellular Component (CC)extracellular space0.019851InformativeInherited
Cellular Component (CC)external side of plasma membrane00Highly InformativeDirect
Cellular Component (CC)receptor complex0.00000000000006640.00000000004747Highly InformativeDirect
Cellular Component (CC)growth cone0.0000000019120.00001673Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) response to stimulus 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) protein metabolic process 0 Least Informative Direct
Biological Process (BP) localization 0 Least Informative Direct
Biological Process (BP) developmental process 0 Least Informative Direct
Biological Process (BP) multicellular organismal process 0 Least Informative Direct
Biological Process (BP) cellular component organization or biogenesis 0 Least Informative Direct
Biological Process (BP) regulation of cellular process 0.4894 Least Informative Inherited
Biological Process (BP) cellular macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) regulation of metabolic process 1 Least Informative Inherited
Biological Process (BP) biosynthetic process 1 Least Informative Inherited
Biological Process (BP) nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) positive regulation of response to stimulus 0 Moderately Informative Direct
Biological Process (BP) signal transduction 0 Moderately Informative Direct
Biological Process (BP) immune system process 0 Moderately Informative Direct
Biological Process (BP) regulation of protein metabolic process 0.0000000000002123 Moderately Informative Direct
Biological Process (BP) nervous system development 0 Moderately Informative Direct
Biological Process (BP) anatomical structure morphogenesis 0 Moderately Informative Direct
Biological Process (BP) multi-organism process 0 Moderately Informative Direct
Biological Process (BP) organ development 0.000000002365 Moderately Informative Direct
Biological Process (BP) cell differentiation 0.0000002116 Moderately Informative Direct
Biological Process (BP) regulation of cellular component organization 0 Moderately Informative Direct
Biological Process (BP) system process 0.00004608 Moderately Informative Direct
Biological Process (BP) regulation of multicellular organismal process 0 Moderately Informative Direct
Biological Process (BP) regulation of developmental process 0 Moderately Informative Direct
Biological Process (BP) single-organism developmental process 0 Moderately Informative Direct
Biological Process (BP) regulation of phosphate metabolic process 0.000000000547 Moderately Informative Direct
Biological Process (BP) positive regulation of cellular process 0.9384 Moderately Informative Inherited
Biological Process (BP) regulation of signal transduction 1 Moderately Informative Inherited
Biological Process (BP) regulation of localization 0.271 Moderately Informative Inherited
Biological Process (BP) regulation of cellular biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule biosynthetic process 1 Moderately Informative Inherited
Biological Process (BP) regulation of nucleobase-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) cellular localization 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) macromolecule localization 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) organelle organization 1 Moderately Informative Inherited
Biological Process (BP) tissue development 0.7357 Moderately Informative Inherited
Biological Process (BP) regulation of catalytic activity 0.5343 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 1 Moderately Informative Inherited
Biological Process (BP) negative regulation of cellular process 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of molecular function 0.1087 Moderately Informative Inherited
Biological Process (BP) negative regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to organic substance 0.004029 Moderately Informative Inherited
Biological Process (BP) cellular response to chemical stimulus 0.2193 Moderately Informative Inherited
Biological Process (BP) response to oxygen-containing compound 1 Moderately Informative Inherited
Biological Process (BP) macromolecular complex subunit organization 1 Moderately Informative Inherited
Biological Process (BP) positive regulation of metabolic process 1 Moderately Informative Inherited
Biological Process (BP) response to endogenous stimulus 1 Moderately Informative Inherited
Biological Process (BP) reproduction 0.003216 Moderately Informative Inherited
Biological Process (BP) ion transport 1 Moderately Informative Inherited
Biological Process (BP) organic substance transport 1 Moderately Informative Inherited
Biological Process (BP) cellular protein modification process 0.002054 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0.06566 Moderately Informative Inherited
Biological Process (BP) vesicle-mediated transport 0 Informative Direct
Biological Process (BP) regulation of immune response 0 Informative Direct
Biological Process (BP) immune response 0 Informative Direct
Biological Process (BP) positive regulation of immune system process 0 Informative Direct
Biological Process (BP) defense response 0 Informative Direct
Biological Process (BP) immune effector process 0.00000000000002112 Informative Direct
Biological Process (BP) biological adhesion 0 Informative Direct
Biological Process (BP) regulation of protein phosphorylation 0.00000003414 Informative Direct
Biological Process (BP) generation of neurons 0 Informative Direct
Biological Process (BP) sensory organ development 0.00000000002676 Informative Direct
Biological Process (BP) regulation of nervous system development 0.00000007316 Informative Direct
Biological Process (BP) negative regulation of cellular component organization 0.0004106 Informative Direct
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.00000005924 Informative Direct
Biological Process (BP) cardiovascular system development 0.00000003277 Informative Direct
Biological Process (BP) cytoskeleton organization 0.0000000000109 Informative Direct
Biological Process (BP) regulation of anatomical structure morphogenesis 0.000000000007167 Informative Direct
Biological Process (BP) response to other organism 0.000000000002874 Informative Direct
Biological Process (BP) cellular component morphogenesis 0 Informative Direct
Biological Process (BP) positive regulation of phosphate metabolic process 0.0000000001913 Informative Direct
Biological Process (BP) regulation of locomotion 0.000000000003761 Informative Direct
Biological Process (BP) tissue morphogenesis 0.0005019 Informative Direct
Biological Process (BP) hematopoietic or lymphoid organ development 0.000000006387 Informative Direct
Biological Process (BP) regulation of intracellular protein kinase cascade 0.0000005417 Informative Direct
Biological Process (BP) tube development 0.00000733 Informative Direct
Biological Process (BP) cellular response to endogenous stimulus 0 Informative Direct
Biological Process (BP) muscle structure development 0 Informative Direct
Biological Process (BP) locomotion 0 Informative Direct
Biological Process (BP) phosphorylation 0 Informative Direct
Biological Process (BP) regulation of cellular component movement 0.00000000221 Informative Direct
Biological Process (BP) positive regulation of protein modification process 0.0000001292 Informative Direct
Biological Process (BP) central nervous system development 0 Informative Direct
Biological Process (BP) cell projection organization 0 Informative Direct
Biological Process (BP) cellular component movement 0 Informative Direct
Biological Process (BP) growth 0 Informative Direct
Biological Process (BP) regulation of cell proliferation 0 Informative Direct
Biological Process (BP) muscle tissue development 0 Informative Direct
Biological Process (BP) localization of cell 0 Informative Direct
Biological Process (BP) peptidyl-amino acid modification 0 Informative Direct
Biological Process (BP) response to cytokine stimulus 0 Informative Direct
Biological Process (BP) organelle assembly 0.000000000000771 Informative Direct
Biological Process (BP) regulation of mitotic cell cycle 0.000000000003877 Informative Direct
Biological Process (BP) regulation of defense response 0.000000000008601 Informative Direct
Biological Process (BP) response to wounding 0.000000002737 Informative Direct
Biological Process (BP) regulation of cytokine production 0.00000006962 Informative Direct
Biological Process (BP) regulation of cell cycle process 0.0000002065 Informative Direct
Biological Process (BP) gland development 0.0000002699 Informative Direct
Biological Process (BP) regulation of establishment of protein localization 0.0000008653 Informative Direct
Biological Process (BP) embryonic organ development 0.00004477 Informative Direct
Biological Process (BP) embryo development ending in birth or egg hatching 0.00009641 Informative Direct
Biological Process (BP) actin filament-based process 0.0003924 Informative Direct
Biological Process (BP) organelle localization 0.000484 Informative Direct
Biological Process (BP) negative regulation of cell death 0.0005417 Informative Direct
Biological Process (BP) positive regulation of developmental process 0.0005752 Informative Direct
Biological Process (BP) regulation of secretion 0.06069 Informative Inherited
Biological Process (BP) positive regulation of cellular biosynthetic process 0.9164 Informative Inherited
Biological Process (BP) positive regulation of nitrogen compound metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of signaling 0.06036 Informative Inherited
Biological Process (BP) negative regulation of cell communication 0.1573 Informative Inherited
Biological Process (BP) regulation of cellular component biogenesis 1 Informative Inherited
Biological Process (BP) enzyme linked receptor protein signaling pathway 1 Informative Inherited
Biological Process (BP) positive regulation of signal transduction 0.9472 Informative Inherited
Biological Process (BP) cellular membrane organization 0.2086 Informative Inherited
Biological Process (BP) cellular chemical homeostasis 0.9122 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 1 Informative Inherited
Biological Process (BP) regulation of system process 1 Informative Inherited
Biological Process (BP) cellular process involved in reproduction 0.06911 Informative Inherited
Biological Process (BP) reproductive system development 1 Informative Inherited
Biological Process (BP) developmental process involved in reproduction 1 Informative Inherited
Biological Process (BP) epithelium development 1 Informative Inherited
Biological Process (BP) organ morphogenesis 0.001391 Informative Inherited
Biological Process (BP) blood circulation 0.6167 Informative Inherited
Biological Process (BP) muscle system process 0.01768 Informative Inherited
Biological Process (BP) positive regulation of multicellular organismal process 0.4963 Informative Inherited
Biological Process (BP) regulation of organelle organization 0.5522 Informative Inherited
Biological Process (BP) microtubule-based process 1 Informative Inherited
Biological Process (BP) negative regulation of response to stimulus 1 Informative Inherited
Biological Process (BP) regulation of growth 0.3731 Informative Inherited
Biological Process (BP) synaptic transmission 1 Informative Inherited
Biological Process (BP) intracellular signal transduction 1 Informative Inherited
Biological Process (BP) positive regulation of cellular component organization 0.7733 Informative Inherited
Biological Process (BP) negative regulation of developmental process 0.3781 Informative Inherited
Biological Process (BP) regulation of cell development 0.01005 Informative Inherited
Biological Process (BP) regulation of kinase activity 1 Informative Inherited
Biological Process (BP) regulation of lipid metabolic process 0.08728 Informative Inherited
Biological Process (BP) regulation of apoptotic process 0.01043 Informative Inherited
Biological Process (BP) embryonic morphogenesis 0.1921 Informative Inherited
Biological Process (BP) positive regulation of macromolecule biosynthetic process 0.7156 Informative Inherited
Biological Process (BP) negative regulation of protein metabolic process 1 Informative Inherited
Biological Process (BP) negative regulation of biosynthetic process 1 Informative Inherited
Biological Process (BP) positive regulation of transport 0.7412 Informative Inherited
Biological Process (BP) dephosphorylation 0.2263 Informative Inherited
Biological Process (BP) cellular macromolecular complex assembly 1 Informative Inherited
Biological Process (BP) mitochondrion organization 1 Informative Inherited
Biological Process (BP) negative regulation of transport 0.9985 Informative Inherited
Biological Process (BP) regulation of ion transport 0.624 Informative Inherited
Biological Process (BP) regulation of intracellular transport 1 Informative Inherited
Biological Process (BP) positive regulation of hydrolase activity 0.1365 Informative Inherited
Biological Process (BP) regulation of hormone levels 1 Informative Inherited
Biological Process (BP) regulation of body fluid levels 0.117 Informative Inherited
Biological Process (BP) multi-multicellular organism process 1 Informative Inherited
Biological Process (BP) multicellular organismal reproductive process 0.6048 Informative Inherited
Biological Process (BP) single organism reproductive process 1 Informative Inherited
Biological Process (BP) sexual reproduction 0.492 Informative Inherited
Biological Process (BP) nitrogen compound transport 1 Informative Inherited
Biological Process (BP) leukocyte activation 0.9455 Informative Inherited
Biological Process (BP) secretion by cell 0.02392 Informative Inherited
Biological Process (BP) regulation of response to external stimulus 1 Informative Inherited
Biological Process (BP) regulation of immune effector process 1 Informative Inherited
Biological Process (BP) cell cycle process 1 Informative Inherited
Biological Process (BP) mitotic cell cycle 1 Informative Inherited
Biological Process (BP) phagocytosis 0 Highly Informative Direct
Biological Process (BP) leukocyte mediated immunity 0 Highly Informative Direct
Biological Process (BP) humoral immune response 0 Highly Informative Direct
Biological Process (BP) immune response-regulating cell surface receptor signaling pathway 0 Highly Informative Direct
Biological Process (BP) positive regulation of cell activation 0 Highly Informative Direct
Biological Process (BP) protein activation cascade 0 Highly Informative Direct
Biological Process (BP) innate immune response 0.0000000001065 Highly Informative Direct
Biological Process (BP) positive regulation of peptidyl-tyrosine phosphorylation 0.0000000002417 Highly Informative Direct
Biological Process (BP) negative regulation of cellular component movement 0.0000161 Highly Informative Direct
Biological Process (BP) angiogenesis 0 Highly Informative Direct
Biological Process (BP) negative regulation of locomotion 0.000004409 Highly Informative Direct
Biological Process (BP) regulation of mononuclear cell proliferation 0 Highly Informative Direct
Biological Process (BP) positive regulation of MAPK cascade 0 Highly Informative Direct
Biological Process (BP) immune response-activating signal transduction 0.00001464 Highly Informative Direct
Biological Process (BP) cell adhesion 0 Highly Informative Direct
Biological Process (BP) cell junction organization 0.00000000006734 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte proliferation 0.0000002628 Highly Informative Direct
Biological Process (BP) transmembrane receptor protein tyrosine kinase signaling pathway 0 Highly Informative Direct
Biological Process (BP) cellular response to growth factor stimulus 0.00000000000005413 Highly Informative Direct
Biological Process (BP) regulation of leukocyte mediated cytotoxicity 0.00000000003308 Highly Informative Direct
Biological Process (BP) regulation of cell morphogenesis involved in differentiation 0.000000000001527 Highly Informative Direct
Biological Process (BP) positive regulation of leukocyte mediated immunity 0.000000000004037 Highly Informative Direct
Biological Process (BP) regulation of adaptive immune response based on somatic recombination of immune receptors built from 0 Highly Informative Direct
Biological Process (BP) regulation of neuron projection development 0 Highly Informative Direct
Biological Process (BP) regulation of lymphocyte mediated immunity 0.0003358 Highly Informative Direct
Biological Process (BP) mesenchyme development 0.000000000002932 Highly Informative Direct
Biological Process (BP) protein folding 0.00000000003018 Highly Informative Direct
Biological Process (BP) regulation of calcium-mediated signaling 0.0000000004546 Highly Informative Direct
Biological Process (BP) respiratory tube development 0.000000000005796 Highly Informative Direct
Biological Process (BP) skeletal system development 0.000001382 Highly Informative Direct
Biological Process (BP) protein phosphorylation 0 Highly Informative Direct
Biological Process (BP) muscle organ development 0.00000000000005088 Highly Informative Direct
Biological Process (BP) renal system development 0.00000002524 Highly Informative Direct
Biological Process (BP) respiratory system development 0.00002646 Highly Informative Direct
Biological Process (BP) chemotaxis 0 Highly Informative Direct
Biological Process (BP) cell part morphogenesis 0.000000008907 Highly Informative Direct
Biological Process (BP) negative regulation of cell proliferation 0 Highly Informative Direct
Biological Process (BP) positive regulation of cell killing 0 Highly Informative Direct
Biological Process (BP) cell morphogenesis involved in differentiation 0 Highly Informative Direct
Biological Process (BP) regulation of T cell activation 0.00003898 Highly Informative Direct
Biological Process (BP) negative regulation of immune system process 0 Highly Informative Direct
Biological Process (BP) antigen processing and presentation 0 Highly Informative Direct
Biological Process (BP) ear development 0 Highly Informative Direct
Biological Process (BP) neuron projection development 0.00000000000002782 Highly Informative Direct
Biological Process (BP) developmental growth 0 Highly Informative Direct
Biological Process (BP) mammary gland epithelium development 0 Highly Informative Direct
Biological Process (BP) peptidyl-tyrosine modification 0 Highly Informative Direct
Biological Process (BP) hair follicle development 0 Highly Informative Direct
Biological Process (BP) hemostasis 0 Highly Informative Direct
Biological Process (BP) cytokine-mediated signaling pathway 0 Highly Informative Direct
Biological Process (BP) regulation of striated muscle tissue development 0 Highly Informative Direct
Biological Process (BP) negative regulation of cell activation 0 Highly Informative Direct
Biological Process (BP) regulation of cytokine biosynthetic process 0 Highly Informative Direct
Biological Process (BP) regulation of mitosis 0 Highly Informative Direct
Biological Process (BP) cardiac muscle tissue development 0 Highly Informative Direct
Biological Process (BP) establishment of synaptic vesicle localization 0.000000000000001931 Highly Informative Direct
Biological Process (BP) stem cell proliferation 0.0000000000000829 Highly Informative Direct
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.0000000000001805 Highly Informative Direct
Biological Process (BP) actomyosin structure organization 0.0000000000009623 Highly Informative Direct
Biological Process (BP) extracellular matrix organization 0.00000000000186 Highly Informative Direct
Biological Process (BP) negative regulation of cell cycle 0.0000000000241 Highly Informative Direct
Biological Process (BP) regulation of neuron apoptotic process 0.00000000004362 Highly Informative Direct
Biological Process (BP) cell growth 0.00000000005461 Highly Informative Direct
Biological Process (BP) regulation of developmental growth 0.0000000001494 Highly Informative Direct
Biological Process (BP) heart morphogenesis 0.000000001464 Highly Informative Direct
Biological Process (BP) regulation of cell division 0.00000000871 Highly Informative Direct
Biological Process (BP) ossification 0.0000000133 Highly Informative Direct
Biological Process (BP) placenta development 0.00000001418 Highly Informative Direct
Biological Process (BP) sensory perception 0.0000000219 Highly Informative Direct
Biological Process (BP) limb morphogenesis 0.0000000506 Highly Informative Direct
Biological Process (BP) female pregnancy 0.0000001535 Highly Informative Direct
Biological Process (BP) cardiocyte differentiation 0.0000004882 Highly Informative Direct
Biological Process (BP) protein dephosphorylation 0.000001034 Highly Informative Direct
Biological Process (BP) positive regulation of adaptive immune response 0.000001777 Highly Informative Direct
Biological Process (BP) coagulation 0.00008656 Highly Informative Direct
Biological Process (BP) carbohydrate homeostasis 0.0001216 Highly Informative Direct
Biological Process (BP) regulation of cytokine secretion 0.0001455 Highly Informative Direct
Biological Process (BP) morphogenesis of embryonic epithelium 0.0001728 Highly Informative Direct
Biological Process (BP) spermatogenesis 0.0001755 Highly Informative Direct
Biological Process (BP) heart contraction 0.0002065 Highly Informative Direct
Biological Process (BP) cellular component assembly involved in morphogenesis 0.0002889 Highly Informative Direct
Biological Process (BP) regulation of cell size 0.0003644 Highly Informative Direct
Biological Process (BP) regulation of multicellular organism growth 0.0005949 Highly Informative Direct
Biological Process (BP) regulation of leukocyte differentiation 0.5557 Highly Informative Inherited
Biological Process (BP) negative regulation of apoptotic process 0.03047 Highly Informative Inherited
Biological Process (BP) regulation of transmembrane transport 1 Highly Informative Inherited
Biological Process (BP) regulation of transporter activity 0.4791 Highly Informative Inherited
Biological Process (BP) regulation of DNA metabolic process 1 Highly Informative Inherited
Biological Process (BP) regulation of actin cytoskeleton organization 0.3589 Highly Informative Inherited
Biological Process (BP) regulation of muscle contraction 0.04246 Highly Informative Inherited
Biological Process (BP) regulation of membrane potential 0.02245 Highly Informative Inherited
Biological Process (BP) response to drug 1 Highly Informative Inherited
Biological Process (BP) positive regulation of protein kinase activity 1 Highly Informative Inherited
Biological Process (BP) response to carbohydrate stimulus 0.9807 Highly Informative Inherited
Biological Process (BP) positive regulation of programmed cell death 0.02935 Highly Informative Inherited
Biological Process (BP) regulation of reproductive process 0.2472 Highly Informative Inherited
Biological Process (BP) regulation of organ morphogenesis 0.01787 Highly Informative Inherited
Biological Process (BP) positive regulation of epithelial cell proliferation 0.007265 Highly Informative Inherited
Biological Process (BP) branching morphogenesis of an epithelial tube 0.003303 Highly Informative Inherited
Biological Process (BP) development of primary female sexual characteristics 0.5725 Highly Informative Inherited
Biological Process (BP) striated muscle contraction 1 Highly Informative Inherited
Biological Process (BP) positive regulation of organelle organization 1 Highly Informative Inherited
Biological Process (BP) spindle organization 0.07155 Highly Informative Inherited
Biological Process (BP) regulation of behavior 1 Highly Informative Inherited
Biological Process (BP) muscle fiber development 0.7337 Highly Informative Inherited
Biological Process (BP) positive regulation of cell cycle process 1 Highly Informative Inherited
Biological Process (BP) negative regulation of cell differentiation 0.8392 Highly Informative Inherited
Biological Process (BP) developmental maturation 1 Highly Informative Inherited
Biological Process (BP) T cell differentiation 0.8957 Highly Informative Inherited
Biological Process (BP) exocytosis 1 Highly Informative Inherited
Biological Process (BP) membrane fusion 1 Highly Informative Inherited
Biological Process (BP) positive regulation of lipid metabolic process 0.01548 Highly Informative Inherited
Biological Process (BP) regulation of binding 0.4552 Highly Informative Inherited
Biological Process (BP) cell fate commitment 1 Highly Informative Inherited
Biological Process (BP) retina development in camera-type eye 0.007628 Highly Informative Inherited
Biological Process (BP) myeloid cell development 1 Highly Informative Inherited
Biological Process (BP) regulation of hormone secretion 1 Highly Informative Inherited
Biological Process (BP) negative regulation of protein transport 1 Highly Informative Inherited
Biological Process (BP) negative regulation of secretion 0.4218 Highly Informative Inherited
Biological Process (BP) post-embryonic organ development 1 Highly Informative Inherited
Biological Process (BP) post-embryonic development 1 Highly Informative Inherited
Biological Process (BP) stem cell development 1 Highly Informative Inherited
Biological Process (BP) regulation of toll-like receptor signaling pathway 0.001869 Highly Informative Inherited
Biological Process (BP) negative regulation of multicellular organismal process 0.4679 Highly Informative Inherited
Biological Process (BP) regulation of peptide transport 0.6721 Highly Informative Inherited
Biological Process (BP) embryonic organ morphogenesis 0.00357 Highly Informative Inherited
Biological Process (BP) leukocyte migration 1 Highly Informative Inherited
Biological Process (BP) establishment or maintenance of cell polarity 0.3331 Highly Informative Inherited
Biological Process (BP) regulation of cell adhesion 0.2141 Highly Informative Inherited
Biological Process (BP) glial cell differentiation 1 Highly Informative Inherited
Biological Process (BP) diencephalon development 0.6399 Highly Informative Inherited
Biological Process (BP) regulation of angiogenesis 1 Highly Informative Inherited
Biological Process (BP) positive regulation of ion transport 0.0623 Highly Informative Inherited
Biological Process (BP) positive regulation of intracellular transport 0.2364 Highly Informative Inherited
Biological Process (BP) positive regulation of homeostatic process 0.237 Highly Informative Inherited
Biological Process (BP) regulation of calcium ion transport 0.1252 Highly Informative Inherited
Biological Process (BP) regulation of ion homeostasis 0.3246 Highly Informative Inherited
Biological Process (BP) regulation of phospholipase activity 0.004308 Highly Informative Inherited
Biological Process (BP) pattern specification process 1 Highly Informative Inherited
Biological Process (BP) cellular hormone metabolic process 0.4258 Highly Informative Inherited
Biological Process (BP) hormone biosynthetic process 0.2551 Highly Informative Inherited
Biological Process (BP) cellular process involved in reproduction in multicellular organism 0.1611 Highly Informative Inherited
Biological Process (BP) female gamete generation 1 Highly Informative Inherited
Biological Process (BP) regulation of acute inflammatory response 0.5227 Highly Informative Inherited
Biological Process (BP) regulation of innate immune response 1 Highly Informative Inherited
Biological Process (BP) inflammatory response 1 Highly Informative Inherited
Biological Process (BP) leukocyte proliferation 0.03624 Highly Informative Inherited
Biological Process (BP) myeloid leukocyte activation 0.7645 Highly Informative Inherited
Biological Process (BP) leukocyte activation involved in immune response 1 Highly Informative Inherited
Biological Process (BP) multi-organism behavior 0.8223 Highly Informative Inherited
Biological Process (BP) eye morphogenesis 0.001256 Highly Informative Inherited
Biological Process (BP) monoamine transport 0.02584 Highly Informative Inherited
Biological Process (BP) positive regulation of response to external stimulus 1 Highly Informative Inherited
Biological Process (BP) positive regulation of defense response 1 Highly Informative Inherited
Molecular Function (MF) binding 0 Least Informative Direct
Molecular Function (MF) transferase activity 0.01515 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) transferase activity, transferring phosphorus-containing groups 0 Moderately Informative Direct
Molecular Function (MF) structural molecule activity 0 Moderately Informative Direct
Molecular Function (MF) hydrolase activity, acting on ester bonds 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 1 Moderately Informative Inherited
Molecular Function (MF) transporter activity 1 Moderately Informative Inherited
Molecular Function (MF) enzyme regulator activity 1 Moderately Informative Inherited
Molecular Function (MF) receptor activity 0 Informative Direct
Molecular Function (MF) molecular transducer activity 0 Informative Direct
Molecular Function (MF) amide binding 0 Informative Direct
Molecular Function (MF) phosphotransferase activity, alcohol group as acceptor 0 Informative Direct
Molecular Function (MF) kinase activity 0 Informative Direct
Molecular Function (MF) protein dimerization activity 0.0006706 Informative Direct
Molecular Function (MF) lipid binding 1 Informative Inherited
Molecular Function (MF) carboxylic acid binding 0.6593 Informative Inherited
Molecular Function (MF) cytoskeletal protein binding 1 Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.002848 Informative Inherited
Molecular Function (MF) sulfur compound binding 0.02697 Informative Inherited
Molecular Function (MF) metal ion transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) inorganic cation transmembrane transporter activity 1 Informative Inherited
Molecular Function (MF) receptor binding 0.002039 Informative Inherited
Molecular Function (MF) GTPase regulator activity 0.9239 Informative Inherited
Molecular Function (MF) enzyme activator activity 0.94 Informative Inherited
Molecular Function (MF) phosphoric ester hydrolase activity 0.5518 Informative Inherited
Molecular Function (MF) antigen binding 0 Highly Informative Direct
Molecular Function (MF) glycolipid binding 0.000000003692 Highly Informative Direct
Molecular Function (MF) peptide binding 0 Highly Informative Direct
Molecular Function (MF) protein kinase activity 0 Highly Informative Direct
Molecular Function (MF) heparin binding 0.000000002627 Highly Informative Direct
Molecular Function (MF) phosphoprotein phosphatase activity 0.0000005306 Highly Informative Direct
Molecular Function (MF) protein homodimerization activity 0.00003451 Highly Informative Direct
Molecular Function (MF) sodium ion transmembrane transporter activity 0.000242 Highly Informative Direct
Molecular Function (MF) phosphatidylinositol binding 0.3133 Highly Informative Inherited
Molecular Function (MF) protein domain specific binding 1 Highly Informative Inherited
Molecular Function (MF) protein complex binding 0.03222 Highly Informative Inherited
Molecular Function (MF) channel regulator activity 0.2027 Highly Informative Inherited
Molecular Function (MF) cation channel activity 0.7497 Highly Informative Inherited
Molecular Function (MF) ion gated channel activity 0.8372 Highly Informative Inherited
Molecular Function (MF) GTPase activator activity 0.2735 Highly Informative Inherited