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p53-like transcription factors superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Common fold of diphtheria toxin/transcription factors/cytochrome f [ 49379] (10)
Superfamily:   p53-like transcription factors [ 49417] (7)
Families:   p53 DNA-binding domain-like [ 81314] (2)
  Rel/Dorsal transcription factors, DNA-binding domain [ 81315] (6)
  T-box [ 81316] (2)
  STAT DNA-binding domain [ 81317] (3)
  RUNT domain [ 81318]
  DNA-binding domain from NDT80 [ 81992]
  DNA-binding protein LAG-1 (CSL) [ 110080]


Superfamily statistics
Genomes (367) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 6,320 19,251 53
Proteins 6,210 18,948 53


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.1041Least InformativeInherited
Disease Ontology (DO)hematologic cancer0.001442Moderately InformativeInherited
Disease Ontology (DO)disease by infectious agent0.004839Moderately InformativeInherited
Disease Ontology (DO)gastrointestinal system disease0.01041Moderately InformativeInherited
Disease Ontology (DO)benign neoplasm0.0246Moderately InformativeInherited
Disease Ontology (DO)head and neck carcinoma0.0000002789InformativeDirect
Disease Ontology (DO)inflammatory bowel disease0.000002655InformativeDirect
Disease Ontology (DO)connective tissue cancer0.00009375InformativeDirect
Disease Ontology (DO)physical disorder0.001156InformativeInherited
Disease Ontology (DO)lymphoma0.007302InformativeInherited
Disease Ontology (DO)breast cancer0.008714InformativeInherited
Disease Ontology (DO)cell type benign neoplasm0.01092InformativeInherited
Disease Ontology (DO)respiratory system cancer0.1016InformativeInherited
Disease Ontology (DO)viral infectious disease0.2672InformativeInherited
Disease Ontology (DO)colitis0.000000088Highly InformativeDirect
Disease Ontology (DO)Burkitt lymphoma0.00002723Highly InformativeDirect
Disease Ontology (DO)mumps0.00006612Highly InformativeDirect
Disease Ontology (DO)Barrett's esophagus0.00007312Highly InformativeDirect
Disease Ontology (DO)gastritis0.0002504Highly InformativeDirect
Disease Ontology (DO)chronic leukemia0.0004027Highly InformativeDirect
Disease Ontology (DO)pertussis0.0004157Highly InformativeDirect
Disease Ontology (DO)progressive multifocal leukoencephalopathy0.000514Highly InformativeDirect
Disease Ontology (DO)laryngeal carcinoma0.0005401Highly InformativeDirect
Disease Ontology (DO)hemangioma0.0005585Highly InformativeDirect
Disease Ontology (DO)salivary gland adenoid cystic carcinoma0.0007397Highly InformativeDirect
Disease Ontology (DO)large intestine cancer0.007613Highly InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.1113Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.1745Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.6136Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.686Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the respiratory system0.000225Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of cardiovascular system morphology0.01535Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the endocrine system0.1595Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of blood and blood-forming tissues0.1877Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vasculature0.2091Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.244Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.3488Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anterior pituitary0.001847InformativeInherited
Phenotypic Abnormality (PA)Abnormal cellular immune system morphology0.01203InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia of the extremities0.04349InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the thorax0.2232InformativeInherited
Phenotypic Abnormality (PA)Anterior hypopituitarism0.0005652Highly InformativeDirect
Phenotypic Abnormality (PA)Leukopenia0.000567Highly InformativeDirect
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving bones of the thorax0.02197Highly InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving bones of the hand0.2219Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)growth/size/body region phenotype0.00000162Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.000002087Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0.0001998Least InformativeDirect
Mammalian Phenotype (MP)cardiovascular system phenotype0.0003366Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.006095Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype0.007581Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.02692Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.1981Least InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology/development0.000000009847Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal leukocyte physiology0.0000004973Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal skeleton morphology0.0000008325Moderately InformativeDirect
Mammalian Phenotype (MP)integument phenotype0.000001235Moderately InformativeDirect
Mammalian Phenotype (MP)embryo phenotype0.000001881Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0.000005405Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal gland morphology0.000009396Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal craniofacial morphology0.000009649Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal mononuclear cell morphology0.00002833Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal blood cell morphology0.00008709Moderately InformativeDirect
Mammalian Phenotype (MP)liver/biliary system phenotype0.0008516Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal inflammatory response0.001434Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune serum protein physiology0.003569Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.005859Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.01536Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.01977Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic cell number0.0304Moderately InformativeInherited
Mammalian Phenotype (MP)neoplasm0.03169Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.0343Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal myeloid cell morphology0.04838Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal heart morphology0.05434Moderately InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.05818Moderately InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.08255Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal digestive system morphology0.1005Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal protein level0.1334Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal professional antigen presenting cell physiology0.4804Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal hormone level0.7245Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal interleukin level0.0000000107InformativeDirect
Mammalian Phenotype (MP)increased susceptibility to infection0.0000003079InformativeDirect
Mammalian Phenotype (MP)abnormal liver physiology0.000003197InformativeDirect
Mammalian Phenotype (MP)abnormal thymus morphology0.00001344InformativeDirect
Mammalian Phenotype (MP)abnormal coat appearance0.0000202InformativeDirect
Mammalian Phenotype (MP)abnormal T cell differentiation0.00003044InformativeDirect
Mammalian Phenotype (MP)abnormal fluid regulation0.00004747InformativeDirect
Mammalian Phenotype (MP)normal phenotype0.00006714InformativeDirect
Mammalian Phenotype (MP)abnormal B cell proliferation0.0001148InformativeDirect
Mammalian Phenotype (MP)hemorrhage0.0001352InformativeDirect
Mammalian Phenotype (MP)altered tumor pathology0.0003109InformativeDirect
Mammalian Phenotype (MP)increased leukocyte cell number0.0004328InformativeDirect
Mammalian Phenotype (MP)abnormal cartilage morphology0.002036InformativeInherited
Mammalian Phenotype (MP)abnormal humoral immune response0.003785InformativeInherited
Mammalian Phenotype (MP)abnormal adaptive thermogenesis0.004061InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord morphology0.008835InformativeInherited
Mammalian Phenotype (MP)abnormal epidermal layer morphology0.01021InformativeInherited
Mammalian Phenotype (MP)abnormal circulating cytokine level0.01222InformativeInherited
Mammalian Phenotype (MP)abnormal gland physiology0.02284InformativeInherited
Mammalian Phenotype (MP)abnormal B lymphocyte antigen presentation0.02881InformativeInherited
Mammalian Phenotype (MP)abnormal head morphology0.04152InformativeInherited
Mammalian Phenotype (MP)abnormal lymph node morphology0.04155InformativeInherited
Mammalian Phenotype (MP)abnormal interferon level0.07081InformativeInherited
Mammalian Phenotype (MP)abnormal mammary gland morphology0.07517InformativeInherited
Mammalian Phenotype (MP)abnormal appendicular skeleton morphology0.07982InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic cage morphology0.2396InformativeInherited
Mammalian Phenotype (MP)abnormal natural killer cell mediated cytotoxicity0.2424InformativeInherited
Mammalian Phenotype (MP)abnormal stomach morphology0.3272InformativeInherited
Mammalian Phenotype (MP)increased hemolymphoid system tumor incidence0.3511InformativeInherited
Mammalian Phenotype (MP)increased carcinoma incidence0.381InformativeInherited
Mammalian Phenotype (MP)abnormal voluntary movement0.4832InformativeInherited
Mammalian Phenotype (MP)abnormal erythroid lineage cell morphology0.5381InformativeInherited
Mammalian Phenotype (MP)abnormal vertebrae morphology0.6989InformativeInherited
Mammalian Phenotype (MP)abnormal Peyer's patch morphology0.8938InformativeInherited
Mammalian Phenotype (MP)decreased B cell proliferation0.000005819Highly InformativeDirect
Mammalian Phenotype (MP)abnormal mammary gland epithelium physiology0.000009113Highly InformativeDirect
Mammalian Phenotype (MP)respiratory system inflammation0.000009659Highly InformativeDirect
Mammalian Phenotype (MP)lethality throughout fetal growth and development, complete penetrance0.00002641Highly InformativeDirect
Mammalian Phenotype (MP)abnormal secondary palate development0.00006083Highly InformativeDirect
Mammalian Phenotype (MP)abnormal intervertebral disk morphology0.0001097Highly InformativeDirect
Mammalian Phenotype (MP)impaired adaptive thermogenesis0.0001287Highly InformativeDirect
Mammalian Phenotype (MP)decreased dendritic cell number0.0001311Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cervical atlas morphology0.0001554Highly InformativeDirect
Mammalian Phenotype (MP)abnormal stomach epithelium morphology0.0001705Highly InformativeDirect
Mammalian Phenotype (MP)cleft palate0.0002123Highly InformativeDirect
Mammalian Phenotype (MP)abnormal level of surface class II molecules0.000275Highly InformativeDirect
Mammalian Phenotype (MP)abnormal thymus medulla morphology0.0003085Highly InformativeDirect
Mammalian Phenotype (MP)abnormal heart development0.0003236Highly InformativeDirect
Mammalian Phenotype (MP)abnormal circulating insulin-like growth factor I level0.0005447Highly InformativeDirect
Mammalian Phenotype (MP)increased adenocarcinoma incidence0.0006211Highly InformativeDirect
Mammalian Phenotype (MP)abnormal granulocyte number0.0006534Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vertebral arch morphology0.0008594Highly InformativeDirect
Mammalian Phenotype (MP)abnormal mammary gland alveolus morphology0.0008594Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord white matter morphology0.008995Highly InformativeInherited
Mammalian Phenotype (MP)abnormal IgG2a level0.01023Highly InformativeInherited
Mammalian Phenotype (MP)abnormal head movements0.01327Highly InformativeInherited
Mammalian Phenotype (MP)increased leukemia incidence0.01366Highly InformativeInherited
Mammalian Phenotype (MP)abnormal bone marrow cell morphology/development0.01868Highly InformativeInherited
Mammalian Phenotype (MP)embryonic lethality during organogenesis0.05987Highly InformativeInherited
Mammalian Phenotype (MP)abnormal Peyer's patch size0.1245Highly InformativeInherited
Mammalian Phenotype (MP)abnormal peripheral lymph node morphology0.1485Highly InformativeInherited
Mammalian Phenotype (MP)abnormal epidermis stratum spinosum morphology0.2191Highly InformativeInherited
Mammalian Phenotype (MP)abnormal neurocranium morphology0.2649Highly InformativeInherited
Mammalian Phenotype (MP)increased IgG level0.3558Highly InformativeInherited
Mammalian Phenotype (MP)abnormal sternum morphology0.8446Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organ system morphology variant0.01968Least InformativeInherited
Worm Phenotype (WP)cell development variant0.05027Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.06125Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.2543Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.2548Least InformativeInherited
Worm Phenotype (WP)cell division variant0.05626Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant1Moderately InformativeInherited
Worm Phenotype (WP)lineage variant0.0004308Highly InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.0006616Highly InformativeDirect
Worm Phenotype (WP)gene expression level reduced0.0007597Highly InformativeDirect
Worm Phenotype (WP)alimentary system morphology variant0.0008322Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)adult0.002121Least InformativeInherited
Fly Anatomy (FA)somatic cell0.007433Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.01108Least InformativeInherited
Fly Anatomy (FA)larva0.1096Least InformativeInherited
Fly Anatomy (FA)anterior-posterior subdivision of organism1Least InformativeInherited
Fly Anatomy (FA)region of integument0.002487Moderately InformativeInherited
Fly Anatomy (FA)thorax0.008425Moderately InformativeInherited
Fly Anatomy (FA)adult segment0.01892Moderately InformativeInherited
Fly Anatomy (FA)sensory system0.02091Moderately InformativeInherited
Fly Anatomy (FA)adult integumentary system0.02903Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.0686Moderately InformativeInherited
Fly Anatomy (FA)adult tagma0.1347Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval circulatory system0.0002356InformativeDirect
Fly Anatomy (FA)mechanosensory system0.0002425InformativeDirect
Fly Anatomy (FA)head mesoderm derived embryonic hemocyte0.0001974Highly InformativeDirect
Fly Anatomy (FA)mesothoracic tergum0.0004526Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.06176Least InformativeInherited
Zebrafish Anatomy (ZA)cardiovascular system0.03547Moderately InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.05458Moderately InformativeInherited
Zebrafish Anatomy (ZA)primary germ layer0.0002194InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)tissue0.1363Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.2767Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.5695Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.75Least InformativeInherited
Xenopus ANatomical entity (XAN)anatomical system1Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk1Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.00003628Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0.0004017Moderately InformativeDirect
Xenopus ANatomical entity (XAN)embryonic structure0.003715Moderately InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.03527Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus0.7458Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm0.7615Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.7725Moderately InformativeInherited
Xenopus ANatomical entity (XAN)mesenchyme0.0000008445InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0.000007696InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0.00001939InformativeDirect
Xenopus ANatomical entity (XAN)neural plate0.00004207InformativeDirect
Xenopus ANatomical entity (XAN)cranial placode0.0002596InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.000286InformativeDirect
Xenopus ANatomical entity (XAN)cardiovascular system0.0005367InformativeDirect
Xenopus ANatomical entity (XAN)peripheral nervous system0.004939InformativeInherited
Xenopus ANatomical entity (XAN)skeletal system0.02927InformativeInherited
Xenopus ANatomical entity (XAN)surface structure0.06232InformativeInherited
Xenopus ANatomical entity (XAN)limb0.6242InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ0.8105InformativeInherited
Xenopus ANatomical entity (XAN)muscle0.9513InformativeInherited
Xenopus ANatomical entity (XAN)hindlimb0.0002976Highly InformativeDirect
Xenopus ANatomical entity (XAN)foregut0.0003113Highly InformativeDirect
Xenopus ANatomical entity (XAN)notochord0.0004201Highly InformativeDirect
Xenopus ANatomical entity (XAN)blastema0.00044Highly InformativeDirect
Xenopus ANatomical entity (XAN)neuron0.0008765Highly InformativeDirect
Xenopus ANatomical entity (XAN)cranium0.001393Highly InformativeInherited
Xenopus ANatomical entity (XAN)gustatory system0.02335Highly InformativeInherited
Xenopus ANatomical entity (XAN)cranial nerve0.0322Highly InformativeInherited
Xenopus ANatomical entity (XAN)branchial arch0.2273Highly InformativeInherited
Xenopus ANatomical entity (XAN)marginal zone1Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.7851Least InformativeInherited
Xenopus DEvelopment stage (XDE)premetamorphosis stage0.01498Highly InformativeInherited

Document: XA annotation of SCOP domains

InterPro annotation
Cross references IPR008967 SSF49417 Protein matches
Abstract

This domain is found in a number of transcription factors, including p53, NFATC, TonEBP, STAT-1, and NFkappaB, where it is responsible for DNA-binding. These transcription factors play diverse roles in the regulation of cellular functions: the p53 tumour suppressor upregulates the expression of genes involved in cell cycle arrest and apoptosis [PubMed12826037]; NFATC regulates the production of effector proteins involved in coordinating the immune response [PubMed8990122]; TonEBP regulates gene expression induced by osmotic stress and helps regulate intracellular volume during cell growth [PubMed12729611]; STAT-1 plays an important role in B lymphocyte growth and function [PubMed12855573]; and NFkappaB is involved in the inflammatory response [PubMed12421671]. The DNA-binding domain acts to clamp, or in the case of TonEBP, encircle the DNA target in order to stabilize the protein-DNA complex [PubMed11780147]. Protein interactions may also serve to stabilize the protein-DNA complex, for example in the STAT-1 dimer the SH2 (Src homology 2) domain in each monomer is coupled to the DNA-binding domain to increase stability [PubMed9630226]. The DNA-binding domain consists of a beta-sandwich formed of 9 strands in 2 sheets with a Greek-key topology. This structure is found in many transcription factors, often within the DNA-binding domain.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 26 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a p53-like transcription factors domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 26 hidden Markov models representing the p53-like transcription factors superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]