SUPERFAMILY 1.75 HMM library and genome assignments server

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Laminin G-like module family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Concanavalin A-like lectins/glucanases [ 49898]
Superfamily:   Concanavalin A-like lectins/glucanases [ 49899] (25)
Family:   Laminin G-like module [ 49944] (6)


Family statistics
Genomes (96) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,194 3,714 22
Proteins 949 3,113 19


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the eye0.002282Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.5563Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.04386Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal eye physiology0.118Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.1467Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the voice0.00166InformativeInherited
Phenotypic Abnormality (PA)Abnormal fundus morphology0.2147InformativeInherited
Phenotypic Abnormality (PA)Abnormal cry0.00005797Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the stomach0.000813Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of retinal pigmentation0.1264Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000001364Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.03745Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.1904Least InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.01737Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.07388Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.09172Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.09338Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.0002359InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system tract morphology0.04922InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.2306InformativeInherited
Mammalian Phenotype (MP)abnormal glial cell morphology0.302InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord morphology0.3934InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.5025InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord ventral commissure morphology0.000001151Highly InformativeDirect
Mammalian Phenotype (MP)abnormal basement membrane morphology0.00001337Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spine curvature0.00002988Highly InformativeDirect
Mammalian Phenotype (MP)decreased excitatory postsynaptic current amplitude0.00009205Highly InformativeDirect
Mammalian Phenotype (MP)abnormal GABA-mediated receptor currents0.0007526Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord white matter morphology0.001411Highly InformativeInherited
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.0113Highly InformativeInherited
Mammalian Phenotype (MP)abnormal neurotransmitter secretion0.03327Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.002216Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.006865Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.01173Moderately InformativeInherited
Worm Phenotype (WP)axon outgrowth variant0.0000005704InformativeDirect
Worm Phenotype (WP)axon guidance variant0.00000005194Highly InformativeDirect
Worm Phenotype (WP)myopodia present0.000001041Highly InformativeDirect
Worm Phenotype (WP)axon morphology variant0.000007209Highly InformativeDirect
Worm Phenotype (WP)muscle system development variant0.0001682Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell polarity defective0.000001147InformativeDirect
Fly Phenotype (FP)cell number defective0.004889InformativeInherited

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)somatic cell0Least InformativeDirect
Fly Anatomy (FA)segment0.002393Least InformativeInherited
Fly Anatomy (FA)tagma0.03154Least InformativeInherited
Fly Anatomy (FA)anatomical group0.04416Least InformativeInherited
Fly Anatomy (FA)nervous system0.05509Least InformativeInherited
Fly Anatomy (FA)larva0.1027Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.1552Least InformativeInherited
Fly Anatomy (FA)adult0.1558Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.001126Moderately InformativeInherited
Fly Anatomy (FA)adult head0.00145Moderately InformativeInherited
Fly Anatomy (FA)cell cluster organ0.01388Moderately InformativeInherited
Fly Anatomy (FA)sense organ0.03147Moderately InformativeInherited
Fly Anatomy (FA)circulatory system0.06121Moderately InformativeInherited
Fly Anatomy (FA)neuron0.07883Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.7507Moderately InformativeInherited
Fly Anatomy (FA)adult optic lobe neuron0.002137InformativeInherited
Fly Anatomy (FA)photoreceptor cell0.002302InformativeInherited
Fly Anatomy (FA)ommatidium0.00637InformativeInherited
Fly Anatomy (FA)histaminergic neuron0.01209InformativeInherited
Fly Anatomy (FA)sensory organ cell0.01322InformativeInherited
Fly Anatomy (FA)embryonic/larval circulatory system0.02057InformativeInherited
Fly Anatomy (FA)embryonic/larval dorsal vessel0.0007331Highly InformativeDirect
Fly Anatomy (FA)photoreceptor cell R40.0009885Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0.01202Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system0.08301Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.2263Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.4788Least InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0.0003442InformativeDirect

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 253 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Concanavalin A-like lectins/glucanases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]