SUPERFAMILY 1.75 HMM library and genome assignments server

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Laminin G-like module family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Concanavalin A-like lectins/glucanases [ 49898]
Superfamily:   Concanavalin A-like lectins/glucanases [ 49899] (25)
Family:   Laminin G-like module [ 49944] (6)


Family statistics
Genomes (96) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,194 3,714 22
Proteins 949 3,113 19


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the eye0.002271Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.5559Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.04363Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal eye physiology0.1178Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.1462Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the voice0.001662InformativeInherited
Phenotypic Abnormality (PA)Abnormal fundus morphology0.215InformativeInherited
Phenotypic Abnormality (PA)Abnormal cry0.00005794Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the stomach0.0008143Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of retinal pigmentation0.1264Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000001371Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.03751Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.1906Least InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.01737Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.07384Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.09169Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.09311Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.0002359InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system tract morphology0.04921InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.2315InformativeInherited
Mammalian Phenotype (MP)abnormal glial cell morphology0.3019InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord morphology0.3934InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.5025InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord ventral commissure morphology0.000001152Highly InformativeDirect
Mammalian Phenotype (MP)abnormal basement membrane morphology0.00001338Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spine curvature0.00002993Highly InformativeDirect
Mammalian Phenotype (MP)decreased excitatory postsynaptic current amplitude0.00009203Highly InformativeDirect
Mammalian Phenotype (MP)abnormal GABA-mediated receptor currents0.0007526Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord white matter morphology0.00141Highly InformativeInherited
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.01129Highly InformativeInherited
Mammalian Phenotype (MP)abnormal neurotransmitter secretion0.03325Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.002036Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.006769Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.01281Moderately InformativeInherited
Worm Phenotype (WP)neuronal outgrowth variant0.0000006965InformativeDirect
Worm Phenotype (WP)nervous system morphology variant0.009685InformativeInherited
Worm Phenotype (WP)axon guidance variant0.00000004945Highly InformativeDirect
Worm Phenotype (WP)myopodia present0.000001037Highly InformativeDirect
Worm Phenotype (WP)axon morphology variant0.000006968Highly InformativeDirect
Worm Phenotype (WP)muscle system development variant0.0001697Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell polarity defective0.000001093InformativeDirect
Fly Phenotype (FP)decreased cell number0.0001008InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)somatic cell0Least InformativeDirect
Fly Anatomy (FA)segment0.002874Least InformativeInherited
Fly Anatomy (FA)tagma0.04047Least InformativeInherited
Fly Anatomy (FA)anatomical group0.04977Least InformativeInherited
Fly Anatomy (FA)nervous system0.06902Least InformativeInherited
Fly Anatomy (FA)larva0.09647Least InformativeInherited
Fly Anatomy (FA)adult0.1868Least InformativeInherited
Fly Anatomy (FA)neuron0.07912Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.6725Moderately InformativeInherited
Fly Anatomy (FA)photoreceptor cell0.002531InformativeInherited
Fly Anatomy (FA)embryonic/larval circulatory system0.02263InformativeInherited
Fly Anatomy (FA)embryonic/larval dorsal vessel0.00079Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0.0115Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system0.08462Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.2272Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.4838Least InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0.0003325InformativeDirect

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 253 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Concanavalin A-like lectins/glucanases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]