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Alcohol dehydrogenase-like, N-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   GroES-like [ 50128] (2)
Superfamily:   GroES-like [ 50129] (2)
Family:   Alcohol dehydrogenase-like, N-terminal domain [ 50136] (15)


Family statistics
Genomes (2,367) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 11,207 52,728 55
Proteins 11,182 52,643 55


Gene Ontology (high-quality)

(
show details) Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0.8846 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate metabolic process 0.00000000003359 Moderately Informative Direct
Biological Process (BP) carboxylic acid metabolic process 0.00000003558 Moderately Informative Direct
Biological Process (BP) lipid metabolic process 0.00001689 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.0003147 Moderately Informative Direct
Biological Process (BP) cellular catabolic process 0.0009432 Moderately Informative Direct
Biological Process (BP) response to chemical 1 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) cellular response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 0.04806 Moderately Informative Inherited
Biological Process (BP) organic cyclic compound biosynthetic process 0.8899 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.885 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.02867 Moderately Informative Inherited
Biological Process (BP) organophosphate metabolic process 0.837 Moderately Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 1 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing small molecule metabolic process 0.7964 Moderately Informative Inherited
Biological Process (BP) small molecule biosynthetic process 0.8951 Moderately Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0 Informative Direct
Biological Process (BP) cellular aldehyde metabolic process 0.0000000007222 Informative Direct
Biological Process (BP) cellular carbohydrate metabolic process 0.00000005763 Informative Direct
Biological Process (BP) small molecule catabolic process 0.00000828 Informative Direct
Biological Process (BP) monosaccharide metabolic process 0.00002814 Informative Direct
Biological Process (BP) carbohydrate catabolic process 0.0001393 Informative Direct
Biological Process (BP) fatty acid metabolic process 0.00021 Informative Direct
Biological Process (BP) movement of cell or subcellular component 1 Informative Inherited
Biological Process (BP) cellular response to oxygen-containing compound 0.9973 Informative Inherited
Biological Process (BP) cellular response to organic substance 1 Informative Inherited
Biological Process (BP) locomotion 1 Informative Inherited
Biological Process (BP) oxidoreduction coenzyme metabolic process 0.02586 Informative Inherited
Biological Process (BP) alpha-amino acid metabolic process 1 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.003112 Informative Inherited
Biological Process (BP) energy derivation by oxidation of organic compounds 0.002576 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.9218 Informative Inherited
Biological Process (BP) organic hydroxy compound catabolic process 0.00000005279 Highly Informative Direct
Biological Process (BP) secondary metabolite biosynthetic process 0.00000458 Highly Informative Direct
Biological Process (BP) response to xenobiotic stimulus 0.000006255 Highly Informative Direct
Biological Process (BP) detoxification 0.00001004 Highly Informative Direct
Biological Process (BP) fatty acid derivative metabolic process 0.00006782 Highly Informative Direct
Biological Process (BP) single-organism carbohydrate catabolic process 0.00009962 Highly Informative Direct
Biological Process (BP) cell wall organization or biogenesis 0.008249 Highly Informative Inherited
Biological Process (BP) glucose metabolic process 0.8608 Highly Informative Inherited
Biological Process (BP) polyol metabolic process 1 Highly Informative Inherited
Biological Process (BP) NAD metabolic process 0.02861 Highly Informative Inherited
Biological Process (BP) terpenoid metabolic process 0.2066 Highly Informative Inherited
Biological Process (BP) alcohol biosynthetic process 0.003664 Highly Informative Inherited
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) oxidoreductase activity 0 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0.000005688 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 1 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.5371 Moderately Informative Inherited
Molecular Function (MF) heterocyclic compound binding 1 Moderately Informative Inherited
Molecular Function (MF) metal ion binding 0.00974 Moderately Informative Inherited
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) zinc ion binding 0.000001316 Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0.0004003 Informative Direct
Molecular Function (MF) nucleotide binding 0.01391 Informative Inherited
Molecular Function (MF) RNA binding 1 Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on CH-OH group of donors 0 Highly Informative Direct
Molecular Function (MF) coenzyme binding 0.00001441 Highly Informative Direct
Molecular Function (MF) oxidoreductase activity, acting on the aldehyde or oxo group of donors 1 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on NAD(P)H 0.004752 Highly Informative Inherited
Molecular Function (MF) oxidoreductase activity, acting on the CH-CH group of donors 0.01341 Highly Informative Inherited
Molecular Function (MF) carbohydrate binding 0.002495 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) cytoplasmic part 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 1 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) cell projection 1 Moderately Informative Inherited
Cellular Component (CC) mitochondrial part 0.8769 Moderately Informative Inherited
Cellular Component (CC) organelle membrane 1 Moderately Informative Inherited
Cellular Component (CC) envelope 1 Moderately Informative Inherited
Cellular Component (CC) cilium 0.07781 Informative Inherited
Cellular Component (CC) whole membrane 1 Informative Inherited
Cellular Component (CC) bounding membrane of organelle 1 Informative Inherited
Cellular Component (CC) motile cilium 0.000002395 Highly Informative Direct
Cellular Component (CC) mitochondrial outer membrane 0.0007434 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Least InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0.6458Moderately InformativeInherited
Enzyme Commission (EC)Acting on the CH-CH group of donors0.099Moderately InformativeInherited
Enzyme Commission (EC)With NAD(+) or NADP(+) as acceptor0InformativeDirect
Enzyme Commission (EC)With a quinone or similar compound as acceptor1.746e-16InformativeDirect
Enzyme Commission (EC)Thiolester hydrolases0.0009207InformativeDirect
Enzyme Commission (EC)Alcohol dehydrogenase0Highly InformativeDirect
Enzyme Commission (EC)Fatty-acid synthase0.0000000000001554Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-acetyltransferase0.000000000001292Highly InformativeDirect
Enzyme Commission (EC)3-hydroxypalmitoyl-[acyl-carrier-protein] dehydrat0.000000000001292Highly InformativeDirect
Enzyme Commission (EC)Oleoyl-[acyl-carrier-protein] hydrolase0.000000000003807Highly InformativeDirect
Enzyme Commission (EC)[Acyl-carrier-protein] S-malonyltransferase0.000000001764Highly InformativeDirect
Enzyme Commission (EC)Enoyl-[acyl-carrier-protein] reductase (NADPH, B-s0.00000000242Highly InformativeDirect
Enzyme Commission (EC)Beta-ketoacyl-acyl-carrier-protein synthase I0.000000005318Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0.00000000001564Moderately InformativeDirect
Biological processLipid metabolism0.0000018Moderately InformativeDirect
Biological processFatty acid metabolism7.557e-16InformativeDirect
Biological processLipid biosynthesis0.05957InformativeInherited
Biological processFatty acid biosynthesis0.00000000000005768Highly InformativeDirect
Cellular componentCytoplasm0.00000008574Least InformativeDirect
Cellular componentMitochondrion0.00000000002875Moderately InformativeDirect
Cellular componentCell projection0.003106Moderately InformativeInherited
Cellular componentCilium0.0000001697Highly InformativeDirect
DomainTransit peptide0.00000002549Moderately InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionZinc0Least InformativeDirect
Molecular functionNAD0Moderately InformativeDirect
Molecular functionNADP0Moderately InformativeDirect
Post-translational modificationTransferase1Least InformativeInherited
Post-translational modificationOxidoreductase0Moderately InformativeDirect
Post-translational modificationAcyltransferase0.00001002InformativeDirect
Post-translational modificationAcetylation0Least InformativeDirect
Post-translational modificationPhosphoprotein0.000000000002114Least InformativeDirect
Post-translational modificationPhosphopantetheine0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 36 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


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Browse and view proteins in genomes which have different domain combinations including a GroES-like domain.


   
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Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]