SUPERFAMILY 1.75 HMM library and genome assignments server

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Elongation factors family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Reductase/isomerase/elongation factor common domain [ 50412] (4)
Superfamily:   Translation proteins [ 50447] (6)
Family:   Elongation factors [ 50448] (10)


Family statistics
Genomes (3,262) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 12,710 110,666 36
Proteins 12,697 110,637 35


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Acting on GTP; involved in cellular and subcellula0Highly InformativeDirect
Enzyme Commission (EC)Adenylyl-sulfate kinase0.00000000000002154Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature0.09083Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.129Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebrum0.0005977Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skull size0.001737Moderately InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0.03425Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of central motor function0.07231Moderately InformativeInherited
Phenotypic Abnormality (PA)Microcephaly0.0003179InformativeDirect
Phenotypic Abnormality (PA)Hypertonia0.06448InformativeInherited

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.03562Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.08045Least InformativeInherited
Worm Phenotype (WP)cell development variant0.3731Least InformativeInherited
Worm Phenotype (WP)protein protein interaction variant0.0008831Moderately InformativeDirect
Worm Phenotype (WP)germ cell differentiation variant0.004005Moderately InformativeInherited
Worm Phenotype (WP)cell cycle variant0.02654Moderately InformativeInherited
Worm Phenotype (WP)germ cell development variant0.02953Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.05067Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.09003Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.1333Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.2926Moderately InformativeInherited
Worm Phenotype (WP)protein expression variant0.4859Moderately InformativeInherited
Worm Phenotype (WP)pachytene progression during oogenesis variant0.00001711InformativeDirect
Worm Phenotype (WP)diplotene progression during oogenesis variant0.00001711InformativeDirect
Worm Phenotype (WP)germ cell compartment expansion variant0.00009969InformativeDirect
Worm Phenotype (WP)rachis morphology variant0.0001081InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.000895InformativeDirect
Worm Phenotype (WP)protein metabolism variant0.01569InformativeInherited
Worm Phenotype (WP)RNA expression variant0.08643InformativeInherited
Worm Phenotype (WP)protein phosphorylation variant0.0001442Highly InformativeDirect
Worm Phenotype (WP)nuclear appearance variant0.0002224Highly InformativeDirect
Worm Phenotype (WP)mRNA levels increased0.0004146Highly InformativeDirect
Worm Phenotype (WP)oocytes small0.0008932Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0.02229Least InformativeInherited
Yeast Phenotype (YP)vegetative growth0.00002667Moderately InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0.2208Least InformativeInherited
Xenopus ANatomical entity (XAN)testis0.006525Moderately InformativeInherited
Xenopus ANatomical entity (XAN)germ cell0.482Moderately InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 42 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Translation proteins domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]