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Transcription factor IIA (TFIIA), beta-barrel domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Transcription factor IIA (TFIIA), beta-barrel domain [ 50783]
Superfamily:   Transcription factor IIA (TFIIA), beta-barrel domain [ 50784]
Families:   Transcription factor IIA (TFIIA), beta-barrel domain [ 50785] (2)


Superfamily statistics
Genomes (466) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,223 3,074 5
Proteins 1,221 3,066 5


Functional annotation
General category Regulation
Detailed category DNA-binding

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) heterocycle metabolic process 0.000000105 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0000001073 Least Informative Direct
Biological Process (BP) cellular aromatic compound metabolic process 0.0000001191 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.0000002683 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.0000003861 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.00001979 Least Informative Direct
Biological Process (BP) primary metabolic process 0.0004317 Least Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.0000000000007856 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.000000000001291 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.000000000005542 Moderately Informative Direct
Biological Process (BP) RNA metabolic process 0.00000000001599 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.00000000002234 Moderately Informative Direct
Biological Process (BP) gene expression 0.00000000009251 Moderately Informative Direct
Biological Process (BP) transcription, DNA-templated 0 Informative Direct
Biological Process (BP) transcription from RNA polymerase II promoter 0 Highly Informative Direct
Molecular Function (MF) binding 0.0198 Least Informative Inherited
Molecular Function (MF) transcription factor activity, transcription factor binding 0.00000000000003587 Highly Informative Direct
Molecular Function (MF) transcription factor binding 0.000000002127 Highly Informative Direct
Cellular Component (CC) protein complex 0.0000000004387 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.000009261 Least Informative Direct
Cellular Component (CC) intracellular organelle part 0.0005261 Least Informative Direct
Cellular Component (CC) transferase complex 0 Moderately Informative Direct
Cellular Component (CC) intracellular organelle lumen 0.0000001481 Moderately Informative Direct
Cellular Component (CC) nuclear part 0.00003639 Moderately Informative Direct
Cellular Component (CC) transferase complex, transferring phosphorus-containing groups 0 Informative Direct
Cellular Component (CC) nucleoplasm part 0 Informative Direct
Cellular Component (CC) RNA polymerase II transcription factor complex 0 Highly Informative Direct

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Cellular componentNucleus0Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR009088 SSF50784 Protein matches
Abstract

This entry represents the beta-barrel domain found at the C-terminal of both TOA1 (or alpha/beta) and TOA2 (or gamma) subunits of TFIIA, and their homologues.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 4 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Transcription factor IIA (TFIIA), beta-barrel domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 4 hidden Markov models representing the Transcription factor IIA (TFIIA), beta-barrel domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]