SUPERFAMILY 1.75 HMM library and genome assignments server

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Nitrous oxide reductase, N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   7-bladed beta-propeller [ 50964] (14)
Superfamily:   Nitrous oxide reductase, N-terminal domain [ 50974]
Families:   Nitrous oxide reductase, N-terminal domain [ 50975]

Superfamily statistics
Genomes (1,193) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 2,011 19,478 3
Proteins 1,912 18,901 3

Functional annotation
General category Metabolism
Detailed category Redox

Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) macromolecular complex binding 0.00000001743 Informative Direct
Molecular Function (MF) cytoskeletal protein binding 0.00000003267 Informative Direct
Molecular Function (MF) actin filament binding 0.00000000000007854 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.02397Least InformativeInherited
Enzyme Commission (EC)Carboxylic ester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)With a cytochrome as acceptor0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processGlucose metabolism0Highly InformativeDirect
Cellular componentCytoplasm1Least InformativeInherited
Cellular componentCytoskeleton0.0000004779Moderately InformativeDirect
Cellular componentPeriplasm0InformativeDirect
DomainWD repeat0.0000000000006044InformativeDirect
Molecular functionCalcium0.0000000001454Moderately InformativeDirect
Molecular functionCopper0InformativeDirect
Post-translational modificationHydrolase0.00000000000000219Least InformativeDirect
Post-translational modificationActin-binding0.000000000001298InformativeDirect
Post-translational modificationAcetylation0.0000000002636Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR011045 SSF50974 Protein matches

Nitrous oxide (N2O) reductase is a copper-containing enzyme that catalyses the two-electron reduction of the greenhouse gas N2O to N2 [PubMed10700275]. N2O reductase has two domains, an N-terminal 7-bladed beta-propeller domain that contains the CuZ catalytic centre, and a C-terminal domain with a cupredoxin fold that is homologous to the CuA domain of bovine cytochrome c oxidase (COXII).

InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Alignments of sequences to 2 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Browse and view proteins in genomes which have different domain combinations including a Nitrous oxide reductase, N-terminal domain domain.

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 2 hidden Markov models representing the Nitrous oxide reductase, N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]