|
GO term |
FDR (all) |
IC level |
SDFO level |
Annotation (direct or inherited) |
| Biological Process (BP) |
cell cycle arrest |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of receptor internalization |
0 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
proteolysis involved in cellular protein catabolic process |
0 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of receptor internalization |
0 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of biological process |
0 |
0.4486 |
-- |
DIRECT |
| Biological Process (BP) |
ubiquitin-dependent protein catabolic process |
0 |
2.097 |
-- |
DIRECT |
| Biological Process (BP) |
protein modification by small protein conjugation |
0 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
biological regulation |
2.076e-15 |
0.4202 |
-- |
DIRECT |
| Biological Process (BP) |
SMAD protein signal transduction |
4.008e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein heterooligomerization |
4.008e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of ion transmembrane transporter activity |
9.754e-15 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein catabolic process |
2.616e-12 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule metabolic process |
5.959e-11 |
0.4634 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell motility |
1.105e-10 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
nephron development |
2.817e-10 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
vacuolar transport |
2.223e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of endocytosis |
2.299e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transporter activity |
2.805e-09 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
vasculogenesis |
4.677e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
modification-dependent macromolecule catabolic process |
5.09e-09 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
peptidyl-lysine trimethylation |
5.656e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of lipase activity |
6.979e-09 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of ion transport |
7.38e-09 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein targeting to vacuole |
1.508e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of dephosphorylation |
1.545e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
kidney epithelium development |
1.996e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule catabolic process |
2.087e-08 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
2.109e-08 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
muscle cell homeostasis |
2.829e-08 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cellular macromolecule localization |
3.614e-08 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
protein localization to vacuole |
4.26e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
transmembrane receptor protein serine/threonine kinase signaling pathway |
6.429e-08 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
1.163e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of transporter activity |
1.219e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of receptor-mediated endocytosis |
1.278e-07 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
covalent chromatin modification |
1.458e-07 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
protein modification process |
1.991e-07 |
0.9066 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of receptor-mediated endocytosis |
2.236e-07 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
cell development |
2.898e-07 |
1.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of intracellular protein kinase cascade |
3.917e-07 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of programmed cell death |
5.403e-07 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
cell migration |
9.563e-07 |
1.658 |
-- |
DIRECT |
| Biological Process (BP) |
signaling |
1.301e-06 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of biological process |
1.396e-06 |
0.8665 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of protein kinase B signaling cascade |
1.777e-06 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
negative regulation of cell migration |
2.049e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell cycle |
2.245e-06 |
1.444 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization to organelle |
3.022e-06 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of hydrolase activity |
3.946e-06 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of endocytosis |
5.859e-06 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
neural tube closure |
6.4e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
chromatin organization |
6.708e-06 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
tube closure |
6.781e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex biogenesis |
7.849e-06 |
1.301 |
-- |
DIRECT |
| Biological Process (BP) |
cellular developmental process |
8.096e-06 |
0.9666 |
-- |
DIRECT |
| Biological Process (BP) |
primary neural tube formation |
8.507e-06 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of systemic arterial blood pressure |
1.209e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
single-organism process |
1.228e-05 |
0.3316 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of phosphate metabolic process |
1.572e-05 |
1.284 |
-- |
DIRECT |
| Biological Process (BP) |
RNA splicing |
1.887e-05 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
neural tube formation |
2.633e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecular complex assembly |
2.793e-05 |
1.252 |
-- |
DIRECT |
| Biological Process (BP) |
cellular component organization |
3.368e-05 |
0.6819 |
-- |
DIRECT |
| Biological Process (BP) |
establishment of protein localization to vacuole |
3.458e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of signal transduction |
4.412e-05 |
1.119 |
-- |
DIRECT |
| Biological Process (BP) |
cellular process |
4.621e-05 |
0.1415 |
-- |
DIRECT |
| Biological Process (BP) |
protein targeting |
4.894e-05 |
1.585 |
-- |
DIRECT |
| Biological Process (BP) |
axon guidance |
5.26e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
macromolecule modification |
5.7e-05 |
0.8416 |
-- |
DIRECT |
| Biological Process (BP) |
neuron migration |
6.05e-05 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
protein stabilization |
6.749e-05 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cellular macromolecule biosynthetic process |
7.619e-05 |
1.119 |
-- |
DIRECT |
| Biological Process (BP) |
extracellular structure organization |
8.362e-05 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of metal ion transport |
9.737e-05 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
embryonic epithelial tube formation |
0.0001269 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
cell projection morphogenesis |
0.0001526 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
renal system development |
0.000174 |
1.921 |
-- |
DIRECT |
| Biological Process (BP) |
cellular response to transforming growth factor beta stimulus |
0.0001811 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
response to transforming growth factor beta stimulus |
0.0001868 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of catabolic process |
0.0001958 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of RNA biosynthetic process |
0.0002078 |
1.167 |
-- |
DIRECT |
| Biological Process (BP) |
receptor metabolic process |
0.0002245 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
blood vessel morphogenesis |
0.0002464 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein localization |
0.0002505 |
1.337 |
-- |
DIRECT |
| Biological Process (BP) |
mesoderm development |
0.0002694 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
primary metabolic process |
0.00028 |
0.2976 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell junction assembly |
0.0003125 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of ion transmembrane transport |
0.0003367 |
2.222 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of JNK cascade |
0.00041 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
positive regulation of cell death |
0.0004492 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
protein complex assembly |
0.0004503 |
1.319 |
-- |
DIRECT |
| Biological Process (BP) |
learning |
0.0004734 |
2.398 |
-- |
DIRECT |
| Biological Process (BP) |
cell part morphogenesis |
0.0004775 |
1.796 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of catabolic process |
0.0006219 |
1.553 |
-- |
DIRECT |
| Biological Process (BP) |
urogenital system development |
0.0006786 |
1.854 |
-- |
DIRECT |
| Biological Process (BP) |
RNA biosynthetic process |
0.0007708 |
1.62 |
-- |
DIRECT |
| Biological Process (BP) |
cellular protein metabolic process |
0.0008788 |
0.6778 |
-- |
DIRECT |
| Biological Process (BP) |
striated muscle cell differentiation |
0.0008888 |
1.745 |
-- |
DIRECT |
| Biological Process (BP) |
peptidyl-lysine methylation |
0.0008915 |
2.699 |
-- |
DIRECT |
| Biological Process (BP) |
regulation of cell motility |
0.05811 |
1.745 |
-- |
INHERITED FROM: negative regulation of cell motility || negative regulation of cell migration |
| Biological Process (BP) |
protein localization |
0.003305 |
1.222 |
-- |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || establishment of protein localization to organelle || receptor clustering || protein targeting to vacuole || protein localization to vacuole || protein localization to membrane || cellular protein localization || protein targeting |
| Biological Process (BP) |
establishment of protein localization |
0.003627 |
1.42 |
-- |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || establishment of protein localization to organelle || protein targeting |
| Biological Process (BP) |
membrane organization |
0.1258 |
1.523 |
-- |
INHERITED FROM: protein localization to membrane || receptor clustering |
| Biological Process (BP) |
epithelial cell differentiation |
0.006078 |
1.658 |
-- |
INHERITED FROM: glomerular visceral epithelial cell differentiation || keratinocyte differentiation || glomerular visceral epithelial cell development || glomerular epithelial cell development || glomerular epithelial cell differentiation || epithelial cell differentiation involved in kidney development |
| Biological Process (BP) |
single-multicellular organism process |
0.003607 |
0.6383 |
-- |
INHERITED FROM: renal system development || glomerular epithelial cell differentiation || embryonic epithelial tube formation || negative regulation of systemic arterial blood pressure || coronary vasculature morphogenesis || neural tube closure || glomerular epithelial cell development || cell migration involved in vasculogenesis || kidney development || notochord development || embryonic placenta development || primary neural tube formation || cell differentiation involved in kidney development || vasculogenesis || negative regulation of blood pressure || embryonic skeletal system development || glomerular visceral epithelial cell differentiation || pericardium development || tube closure || glomerulus development || embryonic cranial skeleton morphogenesis || neuron migration || somatic stem cell maintenance || axon guidance || glomerular visceral epithelial cell development || blood circulation || keratinocyte differentiation || learning || epithelial cell differentiation involved in kidney development || regulation of systemic arterial blood pressure || renal filtration cell differentiation || urogenital system development || embryonic skeletal system morphogenesis || glomerular epithelium development || kidney epithelium development || embryonic placenta morphogenesis || blood vessel morphogenesis || imaginal disc-derived wing vein morphogenesis || nephron development || coronary vasculature development || neural tube formation |
| Biological Process (BP) |
system development |
0.04423 |
0.8069 |
-- |
INHERITED FROM: renal system development || glomerulus development || embryonic cranial skeleton morphogenesis || neuron migration || glomerular epithelial cell differentiation || axon guidance || coronary vasculature morphogenesis || glomerular visceral epithelial cell development || neural tube closure || glomerular epithelial cell development || cell migration involved in vasculogenesis || keratinocyte differentiation || kidney development || epithelial cell differentiation involved in kidney development || notochord development || embryonic placenta development || primary neural tube formation || cell differentiation involved in kidney development || renal filtration cell differentiation || vasculogenesis || urogenital system development || embryonic skeletal system morphogenesis || glomerular epithelium development || kidney epithelium development || embryonic skeletal system development || embryonic placenta morphogenesis || blood vessel morphogenesis || glomerular visceral epithelial cell differentiation || imaginal disc-derived wing vein morphogenesis || nephron development || pericardium development || coronary vasculature development || neural tube formation |
| Biological Process (BP) |
response to growth factor stimulus |
0.04822 |
2 |
-- |
INHERITED FROM: cellular response to transforming growth factor beta stimulus || response to transforming growth factor beta stimulus |
| Biological Process (BP) |
cellular response to stimulus |
0.03833 |
0.7645 |
-- |
INHERITED FROM: cellular response to transforming growth factor beta stimulus || hippo signaling cascade || SMAD protein signal transduction || transmembrane receptor protein serine/threonine kinase signaling pathway || enzyme linked receptor protein signaling pathway |
| Biological Process (BP) |
cellular response to organic substance |
0.4776 |
1.208 |
-- |
INHERITED FROM: cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
response to chemical stimulus |
1 |
0.8861 |
-- |
INHERITED FROM: response to transforming growth factor beta stimulus || cellular response to transforming growth factor beta stimulus || chemotaxis || axon guidance |
| Biological Process (BP) |
cellular component assembly |
0.4167 |
1.076 |
-- |
INHERITED FROM: macromolecular complex assembly || protein complex assembly || protein heterooligomerization |
| Biological Process (BP) |
blood vessel development |
0.001147 |
1.699 |
-- |
INHERITED FROM: coronary vasculature morphogenesis || coronary vasculature development || vasculogenesis || cell migration involved in vasculogenesis || blood vessel morphogenesis |
| Biological Process (BP) |
circulatory system development |
0.1879 |
1.444 |
-- |
INHERITED FROM: coronary vasculature morphogenesis || pericardium development || coronary vasculature development || vasculogenesis || cell migration involved in vasculogenesis || blood vessel morphogenesis |
| Biological Process (BP) |
heart development |
0.003792 |
1.796 |
-- |
INHERITED FROM: coronary vasculature morphogenesis || pericardium development || coronary vasculature development |
| Biological Process (BP) |
vasculature development |
0.004539 |
1.658 |
-- |
INHERITED FROM: coronary vasculature development || coronary vasculature morphogenesis || vasculogenesis || cell migration involved in vasculogenesis || blood vessel morphogenesis |
| Biological Process (BP) |
anatomical structure development |
0.02008 |
0.7212 |
-- |
INHERITED FROM: tube closure || renal system development || glomerulus development || embryonic cranial skeleton morphogenesis || neuron migration || glomerular epithelial cell differentiation || embryonic epithelial tube formation || somatic stem cell maintenance || cell development || axon guidance || coronary vasculature morphogenesis || striated muscle cell differentiation || glomerular visceral epithelial cell development || neural tube closure || mesoderm development || glomerular epithelial cell development || cell migration involved in vasculogenesis || keratinocyte differentiation || kidney development || cell part morphogenesis || epithelial cell differentiation involved in kidney development || notochord development || embryonic placenta development || primary neural tube formation || cell differentiation involved in kidney development || renal filtration cell differentiation || vasculogenesis || urogenital system development || embryonic skeletal system morphogenesis || glomerular epithelium development || kidney epithelium development || cell projection morphogenesis || embryonic skeletal system development || embryonic placenta morphogenesis || blood vessel morphogenesis || glomerular visceral epithelial cell differentiation || imaginal disc-derived wing vein morphogenesis || nephron development || pericardium development || coronary vasculature development || neural tube formation || lateral mesoderm development |
| Biological Process (BP) |
multicellular organismal development |
0.5481 |
0.7496 |
-- |
INHERITED FROM: tube closure || renal system development || glomerulus development || embryonic cranial skeleton morphogenesis || neuron migration || glomerular epithelial cell differentiation || embryonic epithelial tube formation || axon guidance || coronary vasculature morphogenesis || glomerular visceral epithelial cell development || neural tube closure || glomerular epithelial cell development || cell migration involved in vasculogenesis || keratinocyte differentiation || kidney development || epithelial cell differentiation involved in kidney development || notochord development || embryonic placenta development || primary neural tube formation || cell differentiation involved in kidney development || renal filtration cell differentiation || vasculogenesis || urogenital system development || embryonic skeletal system morphogenesis || glomerular epithelium development || kidney epithelium development || embryonic skeletal system development || embryonic placenta morphogenesis || blood vessel morphogenesis || glomerular visceral epithelial cell differentiation || imaginal disc-derived wing vein morphogenesis || nephron development || pericardium development || coronary vasculature development || neural tube formation |
| Biological Process (BP) |
cell surface receptor signaling pathway |
0.6291 |
1.237 |
-- |
INHERITED FROM: SMAD protein signal transduction || transmembrane receptor protein serine/threonine kinase signaling pathway || enzyme linked receptor protein signaling pathway |
| Biological Process (BP) |
muscle cell differentiation |
0.3722 |
1.658 |
-- |
INHERITED FROM: striated muscle cell differentiation |
| Biological Process (BP) |
cell morphogenesis |
0.3228 |
1.658 |
-- |
INHERITED FROM: cell projection morphogenesis || axon guidance |
| Biological Process (BP) |
embryo development |
1 |
1.301 |
-- |
INHERITED FROM: embryonic skeletal system morphogenesis || primary neural tube formation || embryonic cranial skeleton morphogenesis || neural tube closure || notochord development || embryonic placenta development || embryonic skeletal system development || neural tube formation || embryonic placenta morphogenesis || embryonic epithelial tube formation |
| Biological Process (BP) |
skeletal system morphogenesis |
0.01313 |
2.398 |
-- |
INHERITED FROM: embryonic cranial skeleton morphogenesis || embryonic skeletal system morphogenesis |
| Biological Process (BP) |
cellular homeostasis |
0.1555 |
1.284 |
-- |
INHERITED FROM: muscle cell homeostasis |
| Biological Process (BP) |
regulation of stress-activated MAPK cascade |
0.01051 |
2.398 |
-- |
INHERITED FROM: regulation of JNK cascade |
| Biological Process (BP) |
regulation of stress-activated protein kinase signaling cascade |
0.1334 |
2.398 |
-- |
INHERITED FROM: regulation of JNK cascade |
| Biological Process (BP) |
regulation of MAPK cascade |
1 |
1.699 |
-- |
INHERITED FROM: regulation of JNK cascade |
| Biological Process (BP) |
circulatory system process |
0.04334 |
1.745 |
-- |
INHERITED FROM: negative regulation of blood pressure || negative regulation of systemic arterial blood pressure || blood circulation || regulation of systemic arterial blood pressure |
| Biological Process (BP) |
positive regulation of biological process |
0.3532 |
0.8182 |
-- |
INHERITED FROM: positive regulation of protein catabolic process || positive regulation of organ growth || positive regulation of receptor-mediated endocytosis || positive regulation of catabolic process || positive regulation of transporter activity || positive regulation of endocytosis || positive regulation of cell death || positive regulation of transport || positive regulation of receptor internalization |
| Biological Process (BP) |
regulation of primary metabolic process |
1 |
0.7852 |
-- |
INHERITED FROM: positive regulation of protein catabolic process || negative regulation of sequence-specific DNA binding transcription factor activity || regulation of protein catabolic process || regulation of RNA biosynthetic process |
| Biological Process (BP) |
positive regulation of macromolecule metabolic process |
0.07396 |
1.301 |
-- |
INHERITED FROM: positive regulation of protein catabolic process || positive regulation of receptor internalization |
| Biological Process (BP) |
regulation of macromolecule metabolic process |
0.0233 |
0.7959 |
-- |
INHERITED FROM: positive regulation of protein catabolic process || regulation of receptor internalization || negative regulation of sequence-specific DNA binding transcription factor activity || regulation of protein catabolic process || protein stabilization || positive regulation of receptor internalization || regulation of cellular macromolecule biosynthetic process || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of nucleobase-containing compound metabolic process |
0.9438 |
1.027 |
-- |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of RNA metabolic process |
1 |
1.131 |
-- |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of macromolecule biosynthetic process |
1 |
1.066 |
-- |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || regulation of cellular macromolecule biosynthetic process || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of cellular biosynthetic process |
1 |
1.009 |
-- |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || regulation of cellular macromolecule biosynthetic process || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of sequence-specific DNA binding transcription factor activity |
0.2262 |
1.854 |
-- |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity |
| Biological Process (BP) |
regulation of transcription, DNA-dependent |
0.5388 |
1.237 |
-- |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity |
| Biological Process (BP) |
metabolic process |
0.01469 |
0.2411 |
-- |
INHERITED FROM: macromolecule modification || ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || modification-dependent macromolecule catabolic process || cellular protein metabolic process || primary metabolic process || protein modification process || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || proteolysis || mRNA processing || protein metabolic process || RNA biosynthetic process || RNA splicing || protein modification by small protein conjugation or removal || protein ubiquitination || macromolecule metabolic process || modification-dependent protein catabolic process || peptidyl-lysine methylation || ubiquitin-dependent protein catabolic process || peptidyl-lysine trimethylation || histone H3-K36 methylation || cellular macromolecule metabolic process || cellular protein catabolic process || protein catabolic process || protein modification by small protein conjugation || macromolecule catabolic process || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || proteolysis involved in cellular protein catabolic process || cellular macromolecule catabolic process || cellular catabolic process || receptor metabolic process || protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
organic substance metabolic process |
0.001509 |
0.2676 |
-- |
INHERITED FROM: macromolecule modification || ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || modification-dependent macromolecule catabolic process || cellular protein metabolic process || protein modification process || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || proteolysis || mRNA processing || protein metabolic process || RNA biosynthetic process || RNA splicing || protein modification by small protein conjugation or removal || protein ubiquitination || macromolecule metabolic process || modification-dependent protein catabolic process || peptidyl-lysine methylation || ubiquitin-dependent protein catabolic process || peptidyl-lysine trimethylation || histone H3-K36 methylation || cellular macromolecule metabolic process || cellular protein catabolic process || protein catabolic process || protein modification by small protein conjugation || macromolecule catabolic process || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || proteolysis involved in cellular protein catabolic process || cellular macromolecule catabolic process || receptor metabolic process || protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
catabolic process |
0.003356 |
0.7852 |
-- |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || cellular protein catabolic process || ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || protein catabolic process || modification-dependent macromolecule catabolic process || macromolecule catabolic process || proteolysis involved in cellular protein catabolic process || cellular macromolecule catabolic process || cellular catabolic process || protein ubiquitination involved in ubiquitin-dependent protein catabolic process || modification-dependent protein catabolic process || ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
establishment of localization |
1 |
0.7696 |
-- |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || late endosome to vacuole transport via multivesicular body sorting pathway || endosomal transport || vacuolar transport || protein targeting || endosome transport via multivesicular body sorting pathway || establishment of protein localization to vacuole || late endosome to vacuole transport || establishment of protein localization to organelle || protein targeting to vacuole || receptor-mediated endocytosis |
| Biological Process (BP) |
transport |
1 |
0.7747 |
-- |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || late endosome to vacuole transport via multivesicular body sorting pathway || endosomal transport || vacuolar transport || protein targeting || endosome transport via multivesicular body sorting pathway || late endosome to vacuole transport || protein targeting to vacuole || receptor-mediated endocytosis |
| Biological Process (BP) |
single-organism transport |
1 |
0.8013 |
-- |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || late endosome to vacuole transport via multivesicular body sorting pathway || endosomal transport || vacuolar transport || protein targeting || endosome transport via multivesicular body sorting pathway || late endosome to vacuole transport || protein targeting to vacuole |
| Biological Process (BP) |
cellular metabolic process |
0.06 |
0.2708 |
-- |
INHERITED FROM: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || modification-dependent macromolecule catabolic process || cellular protein metabolic process || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || mRNA processing || RNA biosynthetic process || RNA splicing || protein modification by small protein conjugation or removal || protein ubiquitination || modification-dependent protein catabolic process || peptidyl-lysine methylation || ubiquitin-dependent protein catabolic process || peptidyl-lysine trimethylation || histone H3-K36 methylation || cellular macromolecule metabolic process || cellular protein catabolic process || protein modification by small protein conjugation || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || proteolysis involved in cellular protein catabolic process || cellular macromolecule catabolic process || cellular catabolic process || receptor metabolic process || protein ubiquitination involved in ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
biological_process |
0.4539 |
0 |
-- |
INHERITED FROM: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || embryonic epithelial tube formation || cellular component organization or biogenesis || cell development || chemotaxis || regulation of molecular function || negative regulation of cell cycle || mesoderm development || glomerular epithelial cell development || regulation of cell junction assembly || regulation of cell communication || primary metabolic process || extracellular structure organization || protein modification process || response to transforming growth factor beta stimulus || multicellular organismal process || receptor clustering || localization of cell || negative regulation of blood pressure || regulation of phosphate metabolic process || mitotic cell cycle arrest || cell projection morphogenesis || late endosome to vacuole transport || regulation of RNA biosynthetic process || regulation of transmembrane transport || peptidyl-lysine methylation || enzyme linked receptor protein signaling pathway || regulation of activin receptor signaling pathway || histone H3-K36 methylation || regulation of receptor-mediated endocytosis || somatic stem cell maintenance || hippo signaling cascade || keratinocyte differentiation || regulation of phosphatase activity || protein targeting to vacuole || regulation of systemic arterial blood pressure || chromosome organization || negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || regulation of organ growth || renal filtration cell differentiation || glomerular epithelium development || macromolecule catabolic process || regulation of vesicle-mediated transport || negative regulation of intracellular protein kinase cascade || positive regulation of receptor internalization || kidney epithelium development || negative regulation of signal transduction || cellular macromolecule catabolic process || cellular catabolic process || establishment of protein localization to vacuole || imaginal disc-derived wing vein morphogenesis || nephron development || positive regulation of phosphatase activity || negative regulation of locomotion || macromolecule modification || modification-dependent macromolecule catabolic process || developmental process || regulation of cellular macromolecule biosynthetic process || proteolysis || protein metabolic process || RNA biosynthetic process || regulation of signaling || cell migration || notochord development || RNA splicing || regulation of catabolic process || regulation of phosphoprotein phosphatase activity || primary neural tube formation || vasculogenesis || regulation of metal ion transport || protein targeting || pericardium development || ubiquitin-dependent protein catabolic process || tube closure || peptidyl-lysine trimethylation || regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || regulation of biological process || cellular response to transforming growth factor beta stimulus || cellular macromolecule metabolic process || axon guidance || positive regulation of receptor-mediated endocytosis || regulation of receptor internalization || negative regulation of sequence-specific DNA binding transcription factor activity || protein complex assembly || cell part morphogenesis || regulation of hydrolase activity || protein modification by small protein conjugation || proteolysis involved in cellular protein catabolic process || vacuolar transport || embryonic placenta morphogenesis || covalent chromatin modification || protein ubiquitination involved in ubiquitin-dependent protein catabolic process || coronary vasculature development || neural tube formation || cellular macromolecule localization || negative regulation of cellular process || negative regulation of systemic arterial blood pressure || muscle cell homeostasis || regulation of cytokinesis || coronary vasculature morphogenesis || SMAD protein signal transduction || cellular protein metabolic process || protein localization to membrane || protein complex biogenesis || macromolecular complex assembly || transmembrane receptor protein serine/threonine kinase signaling pathway || positive regulation of phosphoprotein phosphatase activity || regulation of lipase activity || receptor-mediated endocytosis || mRNA processing || regulation of transporter activity || protein modification by small protein conjugation or removal || negative regulation of cellular response to growth factor stimulus || regulation of cellular component organization || negative regulation of activin receptor signaling pathway || negative regulation of biological process || regulation of ion transmembrane transporter activity || embryonic skeletal system development || signaling || negative regulation of sodium ion transport || modification-dependent protein catabolic process || cellular component organization || negative regulation of cell communication || lateral mesoderm development || embryonic cranial skeleton morphogenesis || neuron migration || regulation of keratinocyte proliferation || extracellular matrix organization || single-organism process || positive regulation of organ growth || regulation of localization || biological regulation || striated muscle cell differentiation || glomerular visceral epithelial cell development || protein stabilization || negative regulation of cell migration || establishment of protein localization to organelle || protein localization to vacuole || negative regulation of ion transport || localization || protein catabolic process || regulation of JNK cascade || positive regulation of cell death || urogenital system development || regulation of programmed cell death || late endosome to vacuole transport via multivesicular body sorting pathway || regulation of protein catabolic process || cellular process || regulation of ion transmembrane transport || blood vessel morphogenesis || regulation of cellular response to growth factor stimulus || single-organism developmental process || renal system development || glomerular epithelial cell differentiation || regulation of protein kinase B signaling cascade || positive regulation of hydrolase activity || regulation of sodium ion transport || regulation of signal transduction || neural tube closure || regulation of tight junction assembly || regulation of cell cycle || positive regulation of catabolic process || protein heterooligomerization || cell migration involved in vasculogenesis || kidney development || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || negative regulation of signaling || embryonic placenta development || positive regulation of transporter activity || cellular protein localization || negative regulation of protein kinase B signaling cascade || regulation of endocytosis || cell differentiation involved in kidney development || protein ubiquitination || positive regulation of endocytosis || macromolecule metabolic process || negative regulation of cell motility || negative regulation of cellular component movement || positive regulation of transport || glomerular visceral epithelial cell differentiation || regulation of dephosphorylation || glomerulus development || chromatin organization || regulation of hippo signaling cascade || positive regulation of protein catabolic process || cellular developmental process || response to stimulus || negative regulation of epithelial cell differentiation || blood circulation || endosome transport via multivesicular body sorting pathway || regulation of apoptotic process || locomotion || learning || epithelial cell differentiation involved in kidney development || cell cycle arrest || regulation of lipoprotein lipase activity || cellular protein catabolic process || embryonic skeletal system morphogenesis || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || endosomal transport || receptor metabolic process |
| Biological Process (BP) |
regulation of cell death |
0.01498 |
1.301 |
-- |
INHERITED FROM: regulation of programmed cell death || positive regulation of cell death || regulation of apoptotic process |
| Biological Process (BP) |
single organism signaling |
0.001036 |
0.8601 |
-- |
INHERITED FROM: hippo signaling cascade || SMAD protein signal transduction || transmembrane receptor protein serine/threonine kinase signaling pathway || enzyme linked receptor protein signaling pathway |
| Biological Process (BP) |
cell communication |
0.005959 |
0.8477 |
-- |
INHERITED FROM: hippo signaling cascade || SMAD protein signal transduction || transmembrane receptor protein serine/threonine kinase signaling pathway || enzyme linked receptor protein signaling pathway |
| Biological Process (BP) |
regulation of phosphorus metabolic process |
0.03108 |
1.252 |
-- |
INHERITED FROM: regulation of dephosphorylation || positive regulation of phosphatase activity || regulation of phosphoprotein phosphatase activity || regulation of phosphatase activity || regulation of phosphate metabolic process || positive regulation of phosphoprotein phosphatase activity |
| Biological Process (BP) |
stem cell maintenance |
0.02154 |
2.699 |
-- |
INHERITED FROM: somatic stem cell maintenance |
| Biological Process (BP) |
stem cell differentiation |
0.02671 |
2.222 |
-- |
INHERITED FROM: somatic stem cell maintenance |
| Biological Process (BP) |
nucleobase-containing compound biosynthetic process |
0.01895 |
1.167 |
-- |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
cellular biosynthetic process |
1 |
0.5498 |
-- |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
macromolecule biosynthetic process |
1 |
0.8861 |
-- |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
organic substance biosynthetic process |
1 |
0.5376 |
-- |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
positive regulation of molecular function |
0.2394 |
1.222 |
-- |
INHERITED FROM: positive regulation of phosphoprotein phosphatase activity || positive regulation of phosphatase activity || positive regulation of hydrolase activity || positive regulation of transporter activity |
| Biological Process (BP) |
intracellular transport |
0.04013 |
1.194 |
-- |
INHERITED FROM: late endosome to vacuole transport via multivesicular body sorting pathway || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || late endosome to vacuole transport || protein targeting to vacuole || endosomal transport || vacuolar transport || protein targeting || endosome transport via multivesicular body sorting pathway |
| Biological Process (BP) |
establishment of localization in cell |
0.5293 |
1.119 |
-- |
INHERITED FROM: late endosome to vacuole transport via multivesicular body sorting pathway || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || endosomal transport || vacuolar transport || protein targeting || endosome transport via multivesicular body sorting pathway || late endosome to vacuole transport || protein targeting to vacuole |
| Biological Process (BP) |
regulation of cell division |
0.02018 |
2.699 |
-- |
INHERITED FROM: regulation of cytokinesis |
| Biological Process (BP) |
regulation of transmembrane transporter activity |
0.01014 |
2.398 |
-- |
INHERITED FROM: regulation of ion transmembrane transporter activity |
| Biological Process (BP) |
regulation of cell differentiation |
0.6764 |
1.357 |
-- |
INHERITED FROM: negative regulation of epithelial cell differentiation || somatic stem cell maintenance |
| Biological Process (BP) |
negative regulation of cell differentiation |
0.9129 |
1.745 |
-- |
INHERITED FROM: negative regulation of epithelial cell differentiation || somatic stem cell maintenance |
| Biological Process (BP) |
regulation of multicellular organismal development |
0.4932 |
1.268 |
-- |
INHERITED FROM: negative regulation of epithelial cell differentiation |
| Biological Process (BP) |
regulation of cell migration |
0.7995 |
1.745 |
-- |
INHERITED FROM: negative regulation of cell migration |
| Biological Process (BP) |
epidermal cell differentiation |
0.6762 |
2.222 |
-- |
INHERITED FROM: keratinocyte differentiation |
| Biological Process (BP) |
methylation |
0.0011 |
1.854 |
-- |
INHERITED FROM: peptidyl-lysine trimethylation || histone H3-K36 methylation || peptidyl-lysine methylation |
| Biological Process (BP) |
protein alkylation |
0.02136 |
2.097 |
-- |
INHERITED FROM: peptidyl-lysine trimethylation || histone H3-K36 methylation || peptidyl-lysine methylation |
| Biological Process (BP) |
macromolecule methylation |
0.0419 |
1.854 |
-- |
INHERITED FROM: peptidyl-lysine trimethylation || histone H3-K36 methylation || peptidyl-lysine methylation |
| Biological Process (BP) |
morphogenesis of an epithelium |
0.7575 |
1.658 |
-- |
INHERITED FROM: primary neural tube formation || neural tube closure || neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
regulation of catalytic activity |
0.7083 |
1.155 |
-- |
INHERITED FROM: positive regulation of phosphatase activity || regulation of lipoprotein lipase activity || regulation of phosphoprotein phosphatase activity || regulation of phosphatase activity || positive regulation of phosphoprotein phosphatase activity || regulation of lipase activity || positive regulation of hydrolase activity || regulation of hydrolase activity |
| Biological Process (BP) |
regulation of epithelial cell proliferation |
0.5119 |
1.921 |
-- |
INHERITED FROM: regulation of keratinocyte proliferation |
| Biological Process (BP) |
negative regulation of transport |
0.00108 |
1.796 |
-- |
INHERITED FROM: negative regulation of sodium ion transport || negative regulation of ion transport |
| Biological Process (BP) |
chromatin modification |
0.1157 |
1.854 |
-- |
INHERITED FROM: histone H3-K36 methylation || covalent chromatin modification |
| Biological Process (BP) |
histone methylation |
0.02627 |
2.222 |
-- |
INHERITED FROM: histone H3-K36 methylation |
| Biological Process (BP) |
histone lysine methylation |
0.1059 |
2.699 |
-- |
INHERITED FROM: histone H3-K36 methylation |
| Biological Process (BP) |
instar larval or pupal development |
0.04256 |
2.699 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
instar larval or pupal morphogenesis |
0.1139 |
2.699 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
metamorphosis |
0.3092 |
2.699 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
post-embryonic organ morphogenesis |
0.4689 |
2.699 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
appendage development |
0.6278 |
2.097 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
appendage morphogenesis |
0.6524 |
2.097 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
post-embryonic morphogenesis |
0.7769 |
2.222 |
-- |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
RNA processing |
0.05423 |
1.377 |
-- |
INHERITED FROM: RNA splicing || mRNA processing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
cognition |
0.06519 |
2.222 |
-- |
INHERITED FROM: learning |
| Biological Process (BP) |
behavior |
0.3795 |
1.357 |
-- |
INHERITED FROM: learning |
| Biological Process (BP) |
neurological system process |
1 |
1.284 |
-- |
INHERITED FROM: learning |
| Biological Process (BP) |
taxis |
0.08153 |
1.921 |
-- |
INHERITED FROM: axon guidance || chemotaxis |
| Biological Process (BP) |
neuron projection development |
0.005164 |
1.921 |
-- |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
cell morphogenesis involved in neuron differentiation |
0.03013 |
1.921 |
-- |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
neuron projection morphogenesis |
0.1451 |
2 |
-- |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
neuron differentiation |
0.6398 |
1.658 |
-- |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
neuron development |
0.9637 |
1.796 |
-- |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
cell morphogenesis involved in differentiation |
1 |
1.745 |
-- |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
cell cycle |
0.01125 |
1.377 |
-- |
INHERITED FROM: cell cycle arrest || mitotic cell cycle arrest |
| Biological Process (BP) |
endocytosis |
0.2856 |
1.854 |
-- |
INHERITED FROM: receptor-mediated endocytosis |
| Biological Process (BP) |
intracellular protein transport |
0.1451 |
1.553 |
-- |
INHERITED FROM: protein targeting to vacuole || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || protein targeting |
| Biological Process (BP) |
protein complex subunit organization |
0.1086 |
1.194 |
-- |
INHERITED FROM: protein complex assembly || protein heterooligomerization |
| Biological Process (BP) |
nucleobase-containing compound metabolic process |
0.6845 |
0.7305 |
-- |
INHERITED FROM: mRNA processing || RNA biosynthetic process || RNA splicing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
cellular nitrogen compound metabolic process |
1 |
0.585 |
-- |
INHERITED FROM: mRNA processing || RNA biosynthetic process || RNA splicing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
nucleic acid metabolic process |
0.7536 |
0.9066 |
-- |
INHERITED FROM: mRNA processing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || RNA biosynthetic process || RNA splicing |
| Biological Process (BP) |
mRNA metabolic process |
0.03875 |
1.796 |
-- |
INHERITED FROM: mRNA processing |
| Biological Process (BP) |
regulation of biological quality |
1 |
0.8539 |
-- |
INHERITED FROM: regulation of systemic arterial blood pressure || negative regulation of systemic arterial blood pressure || muscle cell homeostasis || negative regulation of blood pressure || protein stabilization |
| Biological Process (BP) |
positive regulation of cellular metabolic process |
0.3128 |
1.208 |
-- |
INHERITED FROM: positive regulation of receptor internalization |
| Biological Process (BP) |
regulation of transport |
0.006525 |
1.155 |
-- |
INHERITED FROM: regulation of sodium ion transport || positive regulation of receptor-mediated endocytosis || regulation of receptor internalization || negative regulation of ion transport || regulation of vesicle-mediated transport || regulation of transporter activity || regulation of metal ion transport || positive regulation of transport || regulation of ion transmembrane transporter activity || positive regulation of receptor internalization || positive regulation of transporter activity || regulation of ion transmembrane transport || regulation of receptor-mediated endocytosis || negative regulation of sodium ion transport || regulation of endocytosis || positive regulation of endocytosis || regulation of transmembrane transport |
| Biological Process (BP) |
placenta development |
0.009394 |
2.222 |
-- |
INHERITED FROM: embryonic placenta development || embryonic placenta morphogenesis |
| Biological Process (BP) |
in utero embryonic development |
0.07904 |
1.745 |
-- |
INHERITED FROM: embryonic placenta development || embryonic placenta morphogenesis |
| Biological Process (BP) |
embryo development ending in birth or egg hatching |
0.8333 |
1.469 |
-- |
INHERITED FROM: embryonic placenta development || embryonic skeletal system development || embryonic cranial skeleton morphogenesis || embryonic skeletal system morphogenesis || neural tube closure || neural tube formation || embryonic placenta morphogenesis || primary neural tube formation |
| Biological Process (BP) |
tube morphogenesis |
0.04905 |
1.854 |
-- |
INHERITED FROM: neural tube closure || tube closure || neural tube formation || primary neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
neural tube development |
0.01081 |
2.398 |
-- |
INHERITED FROM: neural tube closure || neural tube formation || primary neural tube formation |
| Biological Process (BP) |
epithelial tube formation |
0.02371 |
2.222 |
-- |
INHERITED FROM: embryonic epithelial tube formation || neural tube closure || neural tube formation || primary neural tube formation |
| Biological Process (BP) |
cell motility |
0.05303 |
1.585 |
-- |
INHERITED FROM: neuron migration || cell migration || cell migration involved in vasculogenesis |
| Biological Process (BP) |
neurogenesis |
0.8336 |
1.357 |
-- |
INHERITED FROM: neuron migration || axon guidance |
| Biological Process (BP) |
cellular macromolecule metabolic process |
6.458e-14 |
0.4976 |
Least Informative |
DIRECT |
| Biological Process (BP) |
protein metabolic process |
3.453e-07 |
0.6383 |
Least Informative |
DIRECT |
| Biological Process (BP) |
developmental process |
5.692e-07 |
0.6904 |
Least Informative |
DIRECT |
| Biological Process (BP) |
multicellular organismal process |
7.288e-06 |
0.6091 |
Least Informative |
DIRECT |
| Biological Process (BP) |
response to stimulus |
9.881e-05 |
0.5498 |
Least Informative |
DIRECT |
| Biological Process (BP) |
cellular component organization or biogenesis |
0.0001957 |
0.6536 |
Least Informative |
DIRECT |
| Biological Process (BP) |
localization |
0.0008097 |
0.6946 |
Least Informative |
DIRECT |
| Biological Process (BP) |
single-organism cellular process |
0.03931 |
0.3915 |
Least Informative |
INHERITED FROM: cellular macromolecule localization || glomerular epithelial cell differentiation || muscle cell homeostasis || cell development || SMAD protein signal transduction || protein localization to membrane || glomerular epithelial cell development || cell migration involved in vasculogenesis || transmembrane receptor protein serine/threonine kinase signaling pathway || extracellular structure organization || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || cell migration || cellular protein localization || receptor clustering || cell differentiation involved in kidney development || vasculogenesis || mitotic cell cycle arrest || cell projection morphogenesis || protein targeting || late endosome to vacuole transport || glomerular visceral epithelial cell differentiation || enzyme linked receptor protein signaling pathway || histone H3-K36 methylation || chromatin organization || neuron migration || extracellular matrix organization || somatic stem cell maintenance || cellular developmental process || cellular response to transforming growth factor beta stimulus || axon guidance || hippo signaling cascade || striated muscle cell differentiation || glomerular visceral epithelial cell development || endosome transport via multivesicular body sorting pathway || establishment of protein localization to organelle || keratinocyte differentiation || protein targeting to vacuole || protein localization to vacuole || cell part morphogenesis || epithelial cell differentiation involved in kidney development || cell cycle arrest || chromosome organization || renal filtration cell differentiation || late endosome to vacuole transport via multivesicular body sorting pathway || endosomal transport || vacuolar transport || covalent chromatin modification || establishment of protein localization to vacuole |
| Biological Process (BP) |
regulation of metabolic process |
0.4573 |
0.6946 |
Least Informative |
INHERITED FROM: regulation of dephosphorylation || positive regulation of phosphatase activity || positive regulation of protein catabolic process || positive regulation of hydrolase activity || regulation of receptor internalization || negative regulation of sequence-specific DNA binding transcription factor activity || protein stabilization || positive regulation of catabolic process || regulation of cellular macromolecule biosynthetic process || regulation of phosphatase activity || positive regulation of phosphoprotein phosphatase activity || regulation of lipase activity || regulation of lipoprotein lipase activity || regulation of hydrolase activity || regulation of catabolic process || regulation of phosphoprotein phosphatase activity || regulation of phosphate metabolic process || regulation of protein catabolic process || positive regulation of receptor internalization || regulation of RNA biosynthetic process |
| Biological Process (BP) |
biosynthetic process |
1 |
0.52 |
Least Informative |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
regulation of cellular process |
1 |
0.5317 |
Least Informative |
INHERITED FROM: positive regulation of phosphatase activity || negative regulation of cellular process || regulation of protein kinase B signaling cascade || regulation of cytokinesis || regulation of signal transduction || SMAD protein signal transduction || negative regulation of cell cycle || regulation of tight junction assembly || regulation of cell junction assembly || regulation of cell cycle || regulation of cell communication || regulation of cellular macromolecule biosynthetic process || transmembrane receptor protein serine/threonine kinase signaling pathway || positive regulation of phosphoprotein phosphatase activity || negative regulation of cellular response to growth factor stimulus || negative regulation of protein kinase B signaling cascade || regulation of endocytosis || regulation of phosphoprotein phosphatase activity || positive regulation of endocytosis || regulation of cellular component organization || negative regulation of activin receptor signaling pathway || regulation of phosphate metabolic process || negative regulation of cell motility || negative regulation of cellular component movement || mitotic cell cycle arrest || regulation of ion transmembrane transporter activity || regulation of RNA biosynthetic process || regulation of transmembrane transport || negative regulation of cell communication || enzyme linked receptor protein signaling pathway || regulation of dephosphorylation || regulation of activin receptor signaling pathway || regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || regulation of hippo signaling cascade || regulation of receptor-mediated endocytosis || regulation of keratinocyte proliferation || somatic stem cell maintenance || negative regulation of epithelial cell differentiation || hippo signaling cascade || positive regulation of receptor-mediated endocytosis || regulation of receptor internalization || negative regulation of sequence-specific DNA binding transcription factor activity || negative regulation of cell migration || regulation of apoptotic process || regulation of phosphatase activity || cell cycle arrest || negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || regulation of JNK cascade || positive regulation of cell death || regulation of programmed cell death || regulation of vesicle-mediated transport || negative regulation of intracellular protein kinase cascade || positive regulation of receptor internalization || negative regulation of signal transduction || regulation of ion transmembrane transport || regulation of cellular response to growth factor stimulus |
| Biological Process (BP) |
cellular aromatic compound metabolic process |
1 |
0.6271 |
Least Informative |
INHERITED FROM: mRNA processing || RNA biosynthetic process || RNA splicing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
heterocycle metabolic process |
1 |
0.6308 |
Least Informative |
INHERITED FROM: mRNA processing || RNA biosynthetic process || RNA splicing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
organic cyclic compound metabolic process |
1 |
0.5817 |
Least Informative |
INHERITED FROM: mRNA processing || RNA biosynthetic process || RNA splicing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
nitrogen compound metabolic process |
1 |
0.5171 |
Least Informative |
INHERITED FROM: mRNA processing || RNA biosynthetic process || RNA splicing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Biological Process (BP) |
regulation of cell communication |
3.832e-07 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular component organization |
2.824e-06 |
1.18 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of signaling |
3.448e-06 |
1.076 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of localization |
4.828e-06 |
1.066 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular process |
1.092e-05 |
0.9355 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
single-organism developmental process |
0.0002066 |
0.7645 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
cellular catabolic process |
0.0002545 |
0.8928 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
regulation of molecular function |
0.0008486 |
1.056 |
Moderately Informative |
DIRECT |
| Biological Process (BP) |
tissue development |
0.04865 |
1.143 |
Moderately Informative |
INHERITED FROM: glomerular epithelial cell differentiation || embryonic epithelial tube formation || primary neural tube formation || glomerular epithelium development || glomerular visceral epithelial cell development || neural tube closure || mesoderm development || kidney epithelium development || glomerular epithelial cell development || glomerular visceral epithelial cell differentiation || keratinocyte differentiation || pericardium development || neural tube formation || lateral mesoderm development || epithelial cell differentiation involved in kidney development |
| Biological Process (BP) |
response to endogenous stimulus |
1 |
1.237 |
Moderately Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus || response to transforming growth factor beta stimulus |
| Biological Process (BP) |
cellular response to chemical stimulus |
1 |
1.097 |
Moderately Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
response to organic substance |
1 |
1.018 |
Moderately Informative |
INHERITED FROM: response to transforming growth factor beta stimulus || cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
macromolecular complex subunit organization |
0.1982 |
1.131 |
Moderately Informative |
INHERITED FROM: macromolecular complex assembly || protein complex assembly || protein heterooligomerization |
| Biological Process (BP) |
anatomical structure morphogenesis |
0.03638 |
1.036 |
Moderately Informative |
INHERITED FROM: tube closure || embryonic cranial skeleton morphogenesis || embryonic epithelial tube formation || primary neural tube formation || axon guidance || vasculogenesis || embryonic skeletal system morphogenesis || coronary vasculature morphogenesis || neural tube closure || cell projection morphogenesis || embryonic placenta morphogenesis || cell migration involved in vasculogenesis || blood vessel morphogenesis || imaginal disc-derived wing vein morphogenesis || cell part morphogenesis || neural tube formation |
| Biological Process (BP) |
cellular component biogenesis |
0.8785 |
0.983 |
Moderately Informative |
INHERITED FROM: protein heterooligomerization || protein complex biogenesis || macromolecular complex assembly || protein complex assembly |
| Biological Process (BP) |
homeostatic process |
1 |
1.086 |
Moderately Informative |
INHERITED FROM: muscle cell homeostasis |
| Biological Process (BP) |
regulation of multicellular organismal process |
0.7162 |
0.9666 |
Moderately Informative |
INHERITED FROM: positive regulation of organ growth || negative regulation of epithelial cell differentiation || regulation of organ growth |
| Biological Process (BP) |
positive regulation of cellular process |
0.6933 |
0.9066 |
Moderately Informative |
INHERITED FROM: positive regulation of endocytosis || positive regulation of cell death || positive regulation of receptor-mediated endocytosis || positive regulation of receptor internalization |
| Biological Process (BP) |
system process |
0.05634 |
1.131 |
Moderately Informative |
INHERITED FROM: negative regulation of blood pressure || regulation of systemic arterial blood pressure || blood circulation || negative regulation of systemic arterial blood pressure || learning |
| Biological Process (BP) |
regulation of protein metabolic process |
0.5535 |
1.119 |
Moderately Informative |
INHERITED FROM: positive regulation of protein catabolic process || regulation of protein catabolic process |
| Biological Process (BP) |
positive regulation of metabolic process |
0.1225 |
1.167 |
Moderately Informative |
INHERITED FROM: positive regulation of protein catabolic process || positive regulation of receptor internalization || positive regulation of catabolic process |
| Biological Process (BP) |
regulation of nitrogen compound metabolic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of biosynthetic process |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || regulation of cellular macromolecule biosynthetic process || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of gene expression |
1 |
0.9914 |
Moderately Informative |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity || protein stabilization |
| Biological Process (BP) |
macromolecule localization |
0.001878 |
1.046 |
Moderately Informative |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || cellular macromolecule localization || protein localization to membrane || cellular protein localization || protein targeting || establishment of protein localization to vacuole || establishment of protein localization to organelle || receptor clustering || protein targeting to vacuole || protein localization to vacuole |
| Biological Process (BP) |
organic substance catabolic process |
0.002037 |
0.8297 |
Moderately Informative |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || cellular protein catabolic process || ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway || protein catabolic process || modification-dependent macromolecule catabolic process || macromolecule catabolic process || proteolysis involved in cellular protein catabolic process || cellular macromolecule catabolic process || protein ubiquitination involved in ubiquitin-dependent protein catabolic process || modification-dependent protein catabolic process || ubiquitin-dependent protein catabolic process |
| Biological Process (BP) |
organic substance transport |
0.1935 |
0.9747 |
Moderately Informative |
INHERITED FROM: protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || protein targeting || protein targeting to vacuole |
| Biological Process (BP) |
signal transduction |
0.1589 |
0.9914 |
Moderately Informative |
INHERITED FROM: hippo signaling cascade || SMAD protein signal transduction || transmembrane receptor protein serine/threonine kinase signaling pathway || enzyme linked receptor protein signaling pathway |
| Biological Process (BP) |
regulation of cellular metabolic process |
0.8434 |
0.7905 |
Moderately Informative |
INHERITED FROM: regulation of dephosphorylation || positive regulation of phosphatase activity || regulation of receptor internalization || negative regulation of sequence-specific DNA binding transcription factor activity || regulation of cellular macromolecule biosynthetic process || regulation of phosphatase activity || positive regulation of phosphoprotein phosphatase activity || regulation of phosphoprotein phosphatase activity || regulation of phosphate metabolic process || positive regulation of receptor internalization || regulation of RNA biosynthetic process |
| Biological Process (BP) |
regulation of developmental process |
0.5139 |
1.155 |
Moderately Informative |
INHERITED FROM: somatic stem cell maintenance || negative regulation of epithelial cell differentiation |
| Biological Process (BP) |
regulation of response to stimulus |
0.00619 |
0.9914 |
Moderately Informative |
INHERITED FROM: regulation of activin receptor signaling pathway || regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || regulation of hippo signaling cascade || negative regulation of cellular response to growth factor stimulus || negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || regulation of protein kinase B signaling cascade || negative regulation of protein kinase B signaling cascade || regulation of JNK cascade || regulation of signal transduction || negative regulation of activin receptor signaling pathway || negative regulation of intracellular protein kinase cascade || negative regulation of signal transduction || regulation of cellular response to growth factor stimulus |
| Biological Process (BP) |
organ development |
0.7164 |
0.9355 |
Moderately Informative |
INHERITED FROM: glomerulus development || embryonic cranial skeleton morphogenesis || glomerular epithelial cell differentiation || coronary vasculature morphogenesis || glomerular visceral epithelial cell development || glomerular epithelial cell development || keratinocyte differentiation || kidney development || epithelial cell differentiation involved in kidney development || notochord development || embryonic placenta development || cell differentiation involved in kidney development || embryonic skeletal system morphogenesis || glomerular epithelium development || kidney epithelium development || embryonic placenta morphogenesis || glomerular visceral epithelial cell differentiation || imaginal disc-derived wing vein morphogenesis || nephron development || pericardium development || coronary vasculature development |
| Biological Process (BP) |
cellular nitrogen compound biosynthetic process |
0.1305 |
0.9136 |
Moderately Informative |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
heterocycle biosynthetic process |
0.1598 |
0.9355 |
Moderately Informative |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
aromatic compound biosynthetic process |
0.1668 |
0.9747 |
Moderately Informative |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
organic cyclic compound biosynthetic process |
0.3709 |
0.8928 |
Moderately Informative |
INHERITED FROM: RNA biosynthetic process |
| Biological Process (BP) |
cellular localization |
0.02409 |
1.027 |
Moderately Informative |
INHERITED FROM: late endosome to vacuole transport via multivesicular body sorting pathway || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || cellular macromolecule localization || protein localization to membrane || endosomal transport || vacuolar transport || cellular protein localization || protein targeting || endosome transport via multivesicular body sorting pathway || establishment of protein localization to vacuole || late endosome to vacuole transport || establishment of protein localization to organelle || receptor clustering || protein targeting to vacuole || protein localization to vacuole |
| Biological Process (BP) |
cellular protein modification process |
0.001915 |
0.9066 |
Moderately Informative |
INHERITED FROM: peptidyl-lysine trimethylation || histone H3-K36 methylation || protein modification by small protein conjugation or removal || protein ubiquitination involved in ubiquitin-dependent protein catabolic process || protein ubiquitination || peptidyl-lysine methylation || protein modification by small protein conjugation |
| Biological Process (BP) |
organelle organization |
0.8719 |
0.8996 |
Moderately Informative |
INHERITED FROM: histone H3-K36 methylation || chromatin organization || covalent chromatin modification || chromosome organization |
| Biological Process (BP) |
RNA metabolic process |
0.1798 |
1.086 |
Moderately Informative |
INHERITED FROM: mRNA processing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || RNA biosynthetic process || RNA splicing |
| Biological Process (BP) |
gene expression |
0.273 |
0.8729 |
Moderately Informative |
INHERITED FROM: mRNA processing || RNA splicing, via transesterification reactions with bulged adenosine as nucleophile || RNA splicing |
| Biological Process (BP) |
cell differentiation |
0.03889 |
1.009 |
Moderately Informative |
INHERITED FROM: neuron migration || glomerular epithelial cell differentiation || somatic stem cell maintenance || cell differentiation involved in kidney development || cell development || renal filtration cell differentiation || axon guidance || vasculogenesis || striated muscle cell differentiation || glomerular visceral epithelial cell development || glomerular epithelial cell development || cell migration involved in vasculogenesis || glomerular visceral epithelial cell differentiation || keratinocyte differentiation || epithelial cell differentiation involved in kidney development |
| Biological Process (BP) |
nervous system development |
0.331 |
1.194 |
Moderately Informative |
INHERITED FROM: neuron migration || primary neural tube formation || axon guidance || neural tube closure || neural tube formation |
| Biological Process (BP) |
protein modification by small protein conjugation or removal |
7.835e-15 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
protein catabolic process |
4.702e-13 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
cellular macromolecule catabolic process |
3.985e-10 |
1.398 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of apoptotic process |
6.865e-08 |
1.337 |
Informative |
DIRECT |
| Biological Process (BP) |
proteolysis |
8.835e-08 |
1.553 |
Informative |
DIRECT |
| Biological Process (BP) |
positive regulation of transport |
1.338e-07 |
1.495 |
Informative |
DIRECT |
| Biological Process (BP) |
locomotion |
5.432e-07 |
1.444 |
Informative |
DIRECT |
| Biological Process (BP) |
enzyme linked receptor protein signaling pathway |
1.904e-06 |
1.658 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell communication |
8.877e-05 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of signaling |
0.0001575 |
1.699 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of hydrolase activity |
0.0001819 |
1.42 |
Informative |
DIRECT |
| Biological Process (BP) |
localization of cell |
0.0004789 |
1.585 |
Informative |
DIRECT |
| Biological Process (BP) |
blood circulation |
0.0005754 |
1.745 |
Informative |
DIRECT |
| Biological Process (BP) |
chromosome organization |
0.000978 |
1.62 |
Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular component biogenesis |
0.255 |
1.658 |
Informative |
INHERITED FROM: regulation of tight junction assembly || regulation of cell junction assembly |
| Biological Process (BP) |
regulation of cellular component movement |
0.02231 |
1.699 |
Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of cellular component movement || negative regulation of cell migration |
| Biological Process (BP) |
regulation of locomotion |
0.02516 |
1.745 |
Informative |
INHERITED FROM: negative regulation of cell motility || negative regulation of locomotion || negative regulation of cell migration |
| Biological Process (BP) |
protein localization to organelle |
0.9196 |
1.523 |
Informative |
INHERITED FROM: establishment of protein localization to vacuole || protein targeting to vacuole || protein localization to vacuole || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || establishment of protein localization to organelle |
| Biological Process (BP) |
cellular membrane organization |
0.04088 |
1.523 |
Informative |
INHERITED FROM: protein localization to membrane || receptor clustering |
| Biological Process (BP) |
epithelium development |
0.01036 |
1.377 |
Informative |
INHERITED FROM: glomerular epithelium development || glomerular visceral epithelial cell development || neural tube closure || kidney epithelium development || glomerular epithelial cell development || glomerular epithelial cell differentiation || embryonic epithelial tube formation || glomerular visceral epithelial cell differentiation || keratinocyte differentiation || primary neural tube formation || pericardium development || neural tube formation || epithelial cell differentiation involved in kidney development |
| Biological Process (BP) |
cellular response to endogenous stimulus |
0.1951 |
1.377 |
Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
cardiovascular system development |
0.1879 |
1.444 |
Informative |
INHERITED FROM: coronary vasculature morphogenesis || pericardium development || coronary vasculature development || vasculogenesis || cell migration involved in vasculogenesis || blood vessel morphogenesis |
| Biological Process (BP) |
tube development |
0.05897 |
1.62 |
Informative |
INHERITED FROM: tube closure || primary neural tube formation || neural tube closure || neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
anatomical structure formation involved in morphogenesis |
0.5765 |
1.444 |
Informative |
INHERITED FROM: tube closure || neural tube closure || cell migration involved in vasculogenesis || embryonic epithelial tube formation || primary neural tube formation || neural tube formation || vasculogenesis |
| Biological Process (BP) |
protein oligomerization |
0.05568 |
1.658 |
Informative |
INHERITED FROM: protein heterooligomerization |
| Biological Process (BP) |
muscle structure development |
0.002524 |
1.62 |
Informative |
INHERITED FROM: striated muscle cell differentiation |
| Biological Process (BP) |
posttranscriptional regulation of gene expression |
0.4956 |
1.745 |
Informative |
INHERITED FROM: protein stabilization |
| Biological Process (BP) |
cell projection organization |
0.001079 |
1.553 |
Informative |
INHERITED FROM: cell projection morphogenesis || axon guidance |
| Biological Process (BP) |
organ morphogenesis |
0.0918 |
1.523 |
Informative |
INHERITED FROM: embryonic skeletal system morphogenesis || embryonic cranial skeleton morphogenesis || imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
embryonic morphogenesis |
0.5212 |
1.62 |
Informative |
INHERITED FROM: embryonic skeletal system morphogenesis || primary neural tube formation || embryonic cranial skeleton morphogenesis || neural tube closure || neural tube formation || embryonic placenta morphogenesis || embryonic epithelial tube formation |
| Biological Process (BP) |
anatomical structure homeostasis |
0.004558 |
1.745 |
Informative |
INHERITED FROM: muscle cell homeostasis |
| Biological Process (BP) |
regulation of growth |
0.06599 |
1.42 |
Informative |
INHERITED FROM: positive regulation of organ growth || regulation of organ growth |
| Biological Process (BP) |
positive regulation of multicellular organismal process |
0.9713 |
1.585 |
Informative |
INHERITED FROM: positive regulation of organ growth |
| Biological Process (BP) |
regulation of intracellular protein kinase cascade |
0.6928 |
1.469 |
Informative |
INHERITED FROM: regulation of JNK cascade || regulation of protein kinase B signaling cascade || negative regulation of protein kinase B signaling cascade || negative regulation of intracellular protein kinase cascade |
| Biological Process (BP) |
regulation of response to stress |
1 |
1.42 |
Informative |
INHERITED FROM: regulation of JNK cascade |
| Biological Process (BP) |
positive regulation of cellular component organization |
0.001563 |
1.699 |
Informative |
INHERITED FROM: positive regulation of endocytosis || positive regulation of receptor internalization || positive regulation of receptor-mediated endocytosis |
| Biological Process (BP) |
positive regulation of protein metabolic process |
0.6894 |
1.469 |
Informative |
INHERITED FROM: positive regulation of protein catabolic process |
| Biological Process (BP) |
negative regulation of molecular function |
1 |
1.523 |
Informative |
INHERITED FROM: negative regulation of sequence-specific DNA binding transcription factor activity |
| Biological Process (BP) |
intracellular signal transduction |
0.05079 |
1.398 |
Informative |
INHERITED FROM: hippo signaling cascade |
| Biological Process (BP) |
cellular component morphogenesis |
0.07044 |
1.495 |
Informative |
INHERITED FROM: cell part morphogenesis || cell projection morphogenesis || axon guidance |
| Biological Process (BP) |
negative regulation of response to stimulus |
0.002224 |
1.585 |
Informative |
INHERITED FROM: negative regulation of activin receptor signaling pathway || negative regulation of intracellular protein kinase cascade || negative regulation of signal transduction || negative regulation of cellular response to growth factor stimulus || negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway || negative regulation of protein kinase B signaling cascade |
| Biological Process (BP) |
positive regulation of catalytic activity |
0.1435 |
1.337 |
Informative |
INHERITED FROM: positive regulation of phosphoprotein phosphatase activity || positive regulation of phosphatase activity || positive regulation of hydrolase activity |
| Biological Process (BP) |
cytoplasmic transport |
0.00185 |
1.337 |
Informative |
INHERITED FROM: late endosome to vacuole transport via multivesicular body sorting pathway || protein targeting to vacuole || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || late endosome to vacuole transport |
| Biological Process (BP) |
regulation of cell cycle process |
1 |
1.553 |
Informative |
INHERITED FROM: regulation of cytokinesis |
| Biological Process (BP) |
negative regulation of developmental process |
0.9388 |
1.699 |
Informative |
INHERITED FROM: negative regulation of epithelial cell differentiation || somatic stem cell maintenance |
| Biological Process (BP) |
peptidyl-amino acid modification |
0.7246 |
1.377 |
Informative |
INHERITED FROM: peptidyl-lysine trimethylation || peptidyl-lysine methylation |
| Biological Process (BP) |
tissue morphogenesis |
0.3536 |
1.585 |
Informative |
INHERITED FROM: primary neural tube formation || neural tube closure || neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
regulation of cell proliferation |
0.01099 |
1.42 |
Informative |
INHERITED FROM: regulation of keratinocyte proliferation |
| Biological Process (BP) |
single-organism behavior |
0.8369 |
1.523 |
Informative |
INHERITED FROM: learning |
| Biological Process (BP) |
cell cycle process |
0.005051 |
1.377 |
Informative |
INHERITED FROM: cell cycle arrest || mitotic cell cycle arrest |
| Biological Process (BP) |
response to external stimulus |
0.5382 |
1.319 |
Informative |
INHERITED FROM: chemotaxis || axon guidance |
| Biological Process (BP) |
vesicle-mediated transport |
0.8819 |
1.495 |
Informative |
INHERITED FROM: receptor-mediated endocytosis |
| Biological Process (BP) |
protein transport |
0.001501 |
1.469 |
Informative |
INHERITED FROM: protein targeting to vacuole || protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multi || protein targeting |
| Biological Process (BP) |
regulation of ion transport |
0.01322 |
1.585 |
Informative |
INHERITED FROM: regulation of sodium ion transport || regulation of metal ion transport || negative regulation of sodium ion transport || regulation of ion transmembrane transporter activity || negative regulation of ion transport || regulation of ion transmembrane transport |
| Biological Process (BP) |
chordate embryonic development |
0.446 |
1.495 |
Informative |
INHERITED FROM: embryonic placenta development || embryonic skeletal system development || embryonic cranial skeleton morphogenesis || embryonic skeletal system morphogenesis || neural tube closure || neural tube formation || embryonic placenta morphogenesis || primary neural tube formation |
| Biological Process (BP) |
embryonic organ development |
0.03304 |
1.699 |
Informative |
INHERITED FROM: embryonic placenta development || embryonic cranial skeleton morphogenesis || embryonic skeletal system morphogenesis || embryonic placenta morphogenesis || notochord development |
| Biological Process (BP) |
cellular component movement |
0.00378 |
1.398 |
Informative |
INHERITED FROM: neuron migration || cell migration || cell migration involved in vasculogenesis |
| Biological Process (BP) |
generation of neurons |
0.112 |
1.469 |
Informative |
INHERITED FROM: neuron migration || axon guidance |
| Biological Process (BP) |
modification-dependent protein catabolic process |
0 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein ubiquitination |
0 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of transmembrane transport |
3.576e-10 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cell cycle |
5.505e-08 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of protein catabolic process |
6.084e-08 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
protein localization to membrane |
8.895e-08 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
endosomal transport |
1.509e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of sodium ion transport |
2.734e-07 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
extracellular matrix organization |
4.257e-06 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of vesicle-mediated transport |
4.377e-06 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of cellular component movement |
6.291e-06 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
kidney development |
8.94e-06 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of locomotion |
2.249e-05 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of sequence-specific DNA binding transcription factor activity |
2.515e-05 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
negative regulation of signal transduction |
7.401e-05 |
1.854 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
mRNA processing |
0.0002656 |
2 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
chemotaxis |
0.0003902 |
1.921 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
embryonic placenta development |
0.0004369 |
2.222 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
regulation of cellular response to growth factor stimulus |
0.0009883 |
2.097 |
Highly Informative |
DIRECT |
| Biological Process (BP) |
epithelial cell development |
0.001328 |
2 |
Highly Informative |
INHERITED FROM: glomerular visceral epithelial cell development || glomerular epithelial cell development |
| Biological Process (BP) |
cellular response to growth factor stimulus |
0.03994 |
2 |
Highly Informative |
INHERITED FROM: cellular response to transforming growth factor beta stimulus |
| Biological Process (BP) |
regulation of protein stability |
0.002714 |
2.222 |
Highly Informative |
INHERITED FROM: protein stabilization |
| Biological Process (BP) |
skeletal system development |
0.05033 |
2.097 |
Highly Informative |
INHERITED FROM: embryonic skeletal system development || embryonic cranial skeleton morphogenesis || embryonic skeletal system morphogenesis |
| Biological Process (BP) |
embryonic organ morphogenesis |
0.1493 |
2 |
Highly Informative |
INHERITED FROM: embryonic cranial skeleton morphogenesis || embryonic skeletal system morphogenesis |
| Biological Process (BP) |
positive regulation of growth |
0.1995 |
1.854 |
Highly Informative |
INHERITED FROM: positive regulation of organ growth |
| Biological Process (BP) |
regulation of cellular response to stress |
0.1354 |
1.921 |
Highly Informative |
INHERITED FROM: regulation of JNK cascade |
| Biological Process (BP) |
regulation of blood pressure |
0.002435 |
2.222 |
Highly Informative |
INHERITED FROM: negative regulation of blood pressure || negative regulation of systemic arterial blood pressure || regulation of systemic arterial blood pressure |
| Biological Process (BP) |
stem cell development |
0.04472 |
2.222 |
Highly Informative |
INHERITED FROM: somatic stem cell maintenance |
| Biological Process (BP) |
regulation of epithelial cell differentiation |
0.001284 |
2.222 |
Highly Informative |
INHERITED FROM: negative regulation of epithelial cell differentiation |
| Biological Process (BP) |
epidermis development |
0.3987 |
1.854 |
Highly Informative |
INHERITED FROM: keratinocyte differentiation |
| Biological Process (BP) |
peptidyl-lysine modification |
0.001413 |
2 |
Highly Informative |
INHERITED FROM: peptidyl-lysine trimethylation || peptidyl-lysine methylation |
| Biological Process (BP) |
protein methylation |
0.004318 |
2.097 |
Highly Informative |
INHERITED FROM: peptidyl-lysine trimethylation || histone H3-K36 methylation || peptidyl-lysine methylation |
| Biological Process (BP) |
histone modification |
0.02048 |
1.854 |
Highly Informative |
INHERITED FROM: histone H3-K36 methylation |
| Biological Process (BP) |
post-embryonic organ development |
0.6355 |
2.097 |
Highly Informative |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
post-embryonic development |
0.8068 |
1.796 |
Highly Informative |
INHERITED FROM: imaginal disc-derived wing vein morphogenesis |
| Biological Process (BP) |
learning or memory |
0.006082 |
2.222 |
Highly Informative |
INHERITED FROM: learning |
| Biological Process (BP) |
axonogenesis |
0.4811 |
2 |
Highly Informative |
INHERITED FROM: axon guidance |
| Biological Process (BP) |
tube formation |
0.00872 |
2.222 |
Highly Informative |
INHERITED FROM: neural tube closure || neural tube formation || tube closure || primary neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
morphogenesis of embryonic epithelium |
0.02771 |
2 |
Highly Informative |
INHERITED FROM: neural tube closure || neural tube formation || primary neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
epithelial tube morphogenesis |
0.02866 |
1.854 |
Highly Informative |
INHERITED FROM: neural tube closure || neural tube formation || primary neural tube formation || embryonic epithelial tube formation |
| Biological Process (BP) |
RNA splicing, via transesterification reactions |
0.157 |
2.097 |
Highly Informative |
INHERITED FROM: RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| Molecular Function (MF) |
ubiquitin-protein ligase activity |
0 |
2.201 |
-- |
DIRECT |
| Molecular Function (MF) |
sodium channel regulator activity |
0 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
ligase activity |
0 |
1.356 |
-- |
DIRECT |
| Molecular Function (MF) |
acid-amino acid ligase activity |
0 |
1.637 |
-- |
DIRECT |
| Molecular Function (MF) |
ion channel inhibitor activity |
1.251e-13 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
protein complex scaffold |
3.504e-10 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
G-protein coupled receptor binding |
7.923e-10 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
protein domain specific binding |
4.902e-07 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
sodium channel inhibitor activity |
7.22e-07 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
transcription coactivator activity |
8.952e-06 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
protein binding transcription factor activity |
3.606e-05 |
1.9 |
-- |
DIRECT |
| Molecular Function (MF) |
phosphatase binding |
8.076e-05 |
2.377 |
-- |
DIRECT |
| Molecular Function (MF) |
amide binding |
0.0001104 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
actin binding |
0.0003647 |
1.775 |
-- |
DIRECT |
| Molecular Function (MF) |
channel inhibitor activity |
0.0005054 |
2.679 |
-- |
DIRECT |
| Molecular Function (MF) |
molecular_function |
0.08148 |
0 |
-- |
INHERITED FROM: peptide binding || transmembrane receptor protein serine/threonine kinase binding || PDZ domain binding || ligase activity || phosphatase binding || ubiquitin-protein ligase activity || transcription coactivator activity || enzyme binding || SMAD binding || protein domain specific binding || channel inhibitor activity || protein binding transcription factor activity || basal RNA polymerase II transcription machinery binding || protein binding || amide binding || acid-amino acid ligase activity || beta-1 adrenergic receptor binding || RNA polymerase binding || transcription factor binding transcription factor activity || protein complex scaffold || RNA polymerase II core binding || activin receptor binding || type II activin receptor binding || receptor signaling complex scaffold activity || channel regulator activity || proline-rich region binding || protein complex binding || adrenergic receptor binding || beta-amyloid binding || structural molecule activity || sodium channel regulator activity || actin binding || small conjugating protein ligase activity || ligase activity, forming carbon-nitrogen bonds || binding || sodium channel inhibitor activity || G-protein coupled receptor binding || basal transcription machinery binding || receptor serine/threonine kinase binding || ion channel inhibitor activity |
| Molecular Function (MF) |
catalytic activity |
1 |
0.2686 |
-- |
INHERITED FROM: ligase activity || ubiquitin-protein ligase activity || small conjugating protein ligase activity || ligase activity, forming carbon-nitrogen bonds || acid-amino acid ligase activity |
| Molecular Function (MF) |
transcription cofactor activity |
1 |
2.201 |
-- |
INHERITED FROM: transcription coactivator activity |
| Molecular Function (MF) |
binding |
3.07e-15 |
0.3952 |
Least Informative |
DIRECT |
| Molecular Function (MF) |
protein binding |
1.043e-13 |
0.77 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
structural molecule activity |
4.907e-07 |
1.201 |
Moderately Informative |
DIRECT |
| Molecular Function (MF) |
ligase activity, forming carbon-nitrogen bonds |
1.757e-06 |
1.448 |
Informative |
DIRECT |
| Molecular Function (MF) |
enzyme binding |
3.021e-05 |
1.679 |
Informative |
DIRECT |
| Molecular Function (MF) |
receptor binding |
0.006607 |
1.565 |
Informative |
INHERITED FROM: type II activin receptor binding || adrenergic receptor binding || beta-1 adrenergic receptor binding || activin receptor binding || receptor serine/threonine kinase binding || transmembrane receptor protein serine/threonine kinase binding || G-protein coupled receptor binding |
| Molecular Function (MF) |
cytoskeletal protein binding |
0.4683 |
1.423 |
Informative |
INHERITED FROM: actin binding |
| Molecular Function (MF) |
small conjugating protein ligase activity |
0 |
1.833 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
channel regulator activity |
3.343e-11 |
2.201 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
peptide binding |
4.7e-07 |
1.833 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
transcription factor binding transcription factor activity |
1.069e-05 |
2.076 |
Highly Informative |
DIRECT |
| Molecular Function (MF) |
protein complex binding |
0.0006545 |
1.98 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
nucleus |
0 |
0.7857 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle |
9.515e-08 |
0.1836 |
-- |
DIRECT |
| Cellular Component (CC) |
organelle part |
1.082e-07 |
0.3713 |
-- |
DIRECT |
| Cellular Component (CC) |
synapse part |
3.518e-06 |
1.638 |
-- |
DIRECT |
| Cellular Component (CC) |
cell part |
5.291e-06 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
cell |
5.433e-06 |
0.08068 |
-- |
DIRECT |
| Cellular Component (CC) |
macromolecular complex |
3.223e-05 |
0.4276 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular |
3.401e-05 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
site of polarized growth |
0.0002745 |
2.241 |
-- |
DIRECT |
| Cellular Component (CC) |
intracellular part |
0.0003129 |
0.1266 |
-- |
DIRECT |
| Cellular Component (CC) |
non-membrane-bounded organelle |
0.0004757 |
0.6225 |
-- |
DIRECT |
| Cellular Component (CC) |
cytoplasm |
1 |
0.2515 |
-- |
INHERITED FROM: perinuclear region of cytoplasm |
| Cellular Component (CC) |
neuron projection |
0.0168 |
1.638 |
-- |
INHERITED FROM: dendritic spine || dendritic spine head || neuron spine || postsynaptic density |
| Cellular Component (CC) |
cellular_component |
0.3603 |
0 |
-- |
INHERITED FROM: filtration diaphragm || cell || cytoskeleton || postsynaptic density || macromolecular complex || ribonucleoprotein complex || slit diaphragm || organelle part || site of polarized growth || neuron part || apical junction complex || synapse part || actin filament || cell junction || perinuclear region of cytoplasm || dendritic spine || cell part || cell projection || spliceosomal complex || non-membrane-bounded organelle || neuron spine || occluding junction || cell leading edge || adherens junction || cell projection part || dystrophin-associated glycoprotein complex || intracellular part || dendritic spine head || intracellular || intracellular non-membrane-bounded organelle || small nuclear ribonucleoprotein complex || organelle || synapse || nucleus |
| Cellular Component (CC) |
cell periphery |
0.7886 |
0.8256 |
-- |
INHERITED FROM: dystrophin-associated glycoprotein complex |
| Cellular Component (CC) |
plasma membrane part |
0.9218 |
1.036 |
-- |
INHERITED FROM: dystrophin-associated glycoprotein complex |
| Cellular Component (CC) |
membrane part |
1 |
0.6842 |
-- |
INHERITED FROM: dystrophin-associated glycoprotein complex |
| Cellular Component (CC) |
cytoskeletal part |
0.01328 |
1.127 |
-- |
INHERITED FROM: postsynaptic density || actin filament |
| Cellular Component (CC) |
anchoring junction |
0.9423 |
2.064 |
-- |
INHERITED FROM: adherens junction |
| Cellular Component (CC) |
membrane-bounded organelle |
1 |
0.2912 |
-- |
INHERITED FROM: spliceosomal complex || small nuclear ribonucleoprotein complex || nucleus |
| Cellular Component (CC) |
intracellular organelle |
0.2073 |
0.1875 |
-- |
INHERITED FROM: spliceosomal complex || cytoskeleton || postsynaptic density || intracellular non-membrane-bounded organelle || small nuclear ribonucleoprotein complex || nucleus || actin filament |
| Cellular Component (CC) |
intracellular non-membrane-bounded organelle |
0.0005191 |
0.6225 |
Least Informative |
DIRECT |
| Cellular Component (CC) |
cytoplasmic part |
1 |
0.2605 |
Least Informative |
INHERITED FROM: perinuclear region of cytoplasm |
| Cellular Component (CC) |
protein complex |
1 |
0.5639 |
Least Informative |
INHERITED FROM: dystrophin-associated glycoprotein complex || actin filament |
| Cellular Component (CC) |
membrane |
0.7153 |
0.5731 |
Least Informative |
INHERITED FROM: dystrophin-associated glycoprotein complex |
| Cellular Component (CC) |
intracellular membrane-bounded organelle |
1 |
0.2961 |
Least Informative |
INHERITED FROM: spliceosomal complex || small nuclear ribonucleoprotein complex || nucleus |
| Cellular Component (CC) |
intracellular organelle part |
0.03532 |
0.3893 |
Least Informative |
INHERITED FROM: spliceosomal complex || postsynaptic density || small nuclear ribonucleoprotein complex || actin filament |
| Cellular Component (CC) |
cell projection |
2.334e-09 |
1.079 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
cytoskeleton |
6.87e-05 |
1.036 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
ribonucleoprotein complex |
0.0001066 |
0.9505 |
Moderately Informative |
DIRECT |
| Cellular Component (CC) |
nuclear part |
0.003201 |
0.9505 |
Moderately Informative |
INHERITED FROM: small nuclear ribonucleoprotein complex || spliceosomal complex |
| Cellular Component (CC) |
plasma membrane |
0.8228 |
0.9734 |
Moderately Informative |
INHERITED FROM: dystrophin-associated glycoprotein complex |
| Cellular Component (CC) |
synapse |
0 |
1.462 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell projection part |
1.163e-10 |
1.337 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell junction |
3.744e-10 |
1.5 |
Informative |
DIRECT |
| Cellular Component (CC) |
neuron part |
1.856e-07 |
1.542 |
Informative |
DIRECT |
| Cellular Component (CC) |
cell leading edge |
2.925e-05 |
1.638 |
Informative |
DIRECT |
| Cellular Component (CC) |
actin cytoskeleton |
0.1416 |
1.428 |
Informative |
INHERITED FROM: actin filament |
| Cellular Component (CC) |
spliceosomal complex |
1.203e-12 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
perinuclear region of cytoplasm |
1.213e-07 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
actin filament |
8.906e-05 |
2.241 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
small nuclear ribonucleoprotein complex |
0.0001006 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
adherens junction |
0.000771 |
2.064 |
Highly Informative |
DIRECT |
| Cellular Component (CC) |
dendrite |
0.1814 |
2.064 |
Highly Informative |
INHERITED FROM: dendritic spine || dendritic spine head || postsynaptic density |
| Cellular Component (CC) |
cell-cell junction |
0.8159 |
1.763 |
Highly Informative |
INHERITED FROM: filtration diaphragm || apical junction complex || slit diaphragm || occluding junction |
0
7846762
