SUPERFAMILY 1.75 HMM library and genome assignments server

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Biotinyl/lipoyl-carrier proteins and domains family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Barrel-sandwich hybrid [ 51229] (4)
Superfamily:   Single hybrid motif [ 51230]
Family:   Biotinyl/lipoyl-carrier proteins and domains [ 51231] (6)


Family statistics
Genomes (2,345) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 6,514 42,587 16
Proteins 5,667 37,897 16


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0.000000000009127Least InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Forming carbon-nitrogen bonds0.1147Moderately InformativeInherited
Enzyme Commission (EC)Other carbon--nitrogen ligases0InformativeDirect
Enzyme Commission (EC)Biotin carboxylase0Highly InformativeDirect
Enzyme Commission (EC)Pyruvate carboxylase3.476e-16Highly InformativeDirect
Enzyme Commission (EC)Methylcrotonoyl-CoA carboxylase0.000001601Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)disease of metabolism0.00007877Moderately InformativeDirect
Disease Ontology (DO)hypersensitivity reaction type II disease0.01347Moderately InformativeInherited
Disease Ontology (DO)gastrointestinal system disease0.03666Moderately InformativeInherited
Disease Ontology (DO)liver disease0.008841InformativeInherited
Disease Ontology (DO)autoimmune disease of urogenital tract0.000004908Highly InformativeDirect
Disease Ontology (DO)liver cirrhosis0.0002786Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.009883Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature0.01864Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.1011Least InformativeInherited
Phenotypic Abnormality (PA)Muscular hypotonia0.0003999Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of higher mental function0.01102Moderately InformativeInherited
Phenotypic Abnormality (PA)Behavioral abnormality0.0143Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating metabolite concentration0.01573Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal homeostasis0.2432Moderately InformativeInherited
Phenotypic Abnormality (PA)Acidosis0.000004863InformativeDirect
Phenotypic Abnormality (PA)Abnormal circulating carboxylic acid concentration0.00002925InformativeDirect
Phenotypic Abnormality (PA)Reduced consciousness/confusion0.01312InformativeInherited
Phenotypic Abnormality (PA)Abnormal glucose homeostasis0.1318InformativeInherited
Phenotypic Abnormality (PA)Psychomotor retardation0.0002162Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)slow growth0Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.1249Least InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.0002159Moderately InformativeDirect
Worm Phenotype (WP)transgene expression increased0.000003847InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)nervous system0Least InformativeDirect
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect
Zebrafish Anatomy (ZA)sensory system0Moderately InformativeDirect
Zebrafish Anatomy (ZA)head0Moderately InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)branch0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0.00008078Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0.001782Least InformativeInherited
Plant ANatomical entity (PAN)microgametophyte0.01906Least InformativeInherited
Plant ANatomical entity (PAN)androecium0.0462Least InformativeInherited
Plant ANatomical entity (PAN)leaf lamina0.06555Least InformativeInherited
Plant ANatomical entity (PAN)shoot internode0.09149Least InformativeInherited
Plant ANatomical entity (PAN)stem0.5197Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll0.7091Least InformativeInherited
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0.000000001856Least InformativeDirect
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Ligases0.000000000001254Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0InformativeDirect
Enzyme Commission (EC)Translocases0.04972InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0.748InformativeInherited
Enzyme Commission (EC)Catalysing the translocation of inorganic cations0.0000003422Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
DomainLipoyl0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 23 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Single hybrid motif domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]