SUPERFAMILY 1.75 HMM library and genome assignments server

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Alanine racemase-like, N-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   TIM beta/alpha-barrel [ 51350] (33)
Superfamily:   PLP-binding barrel [ 51419] (2)
Family:   Alanine racemase-like, N-terminal domain [ 51420] (3)


Family statistics
Genomes (2,812) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 5,991 35,431 15
Proteins 5,983 35,404 15


Gene Ontology (high-coverage)

(
show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) organonitrogen compound metabolic process 0.0000000001236 Least Informative Direct
Biological Process (BP) biosynthetic process 0.0000000008834 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.0003167 Least Informative Direct
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 0.01154 Least Informative Inherited
Biological Process (BP) single-organism cellular process 0.5283 Least Informative Inherited
Biological Process (BP) carboxylic acid metabolic process 0.0000000000372 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.00006846 Moderately Informative Direct
Biological Process (BP) regulation of localization 0.07265 Moderately Informative Inherited
Biological Process (BP) regulation of primary metabolic process 0.03167 Moderately Informative Inherited
Biological Process (BP) regulation of macromolecule metabolic process 0.03916 Moderately Informative Inherited
Biological Process (BP) negative regulation of biological process 0.4408 Moderately Informative Inherited
Biological Process (BP) regulation of nitrogen compound metabolic process 0.02328 Moderately Informative Inherited
Biological Process (BP) cellular biogenic amine metabolic process 0 Informative Direct
Biological Process (BP) alpha-amino acid metabolic process 0 Informative Direct
Biological Process (BP) regulation of catabolic process 0.00000000000004161 Informative Direct
Biological Process (BP) positive regulation of transport 0.000607 Informative Direct
Biological Process (BP) negative regulation of nitrogen compound metabolic process 0.04176 Informative Inherited
Biological Process (BP) negative regulation of macromolecule metabolic process 0.07533 Informative Inherited
Biological Process (BP) polyamine metabolic process 0 Highly Informative Direct
Biological Process (BP) regulation of protein catabolic process 0 Highly Informative Direct
Biological Process (BP) amine biosynthetic process 0 Highly Informative Direct
Biological Process (BP) ammonium ion metabolic process 0.000000000000004573 Highly Informative Direct
Biological Process (BP) positive regulation of transmembrane transport 0.000000001034 Highly Informative Direct
Biological Process (BP) negative regulation of catabolic process 0.00000004609 Highly Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0 Moderately Informative Direct
Molecular Function (MF) heterocyclic compound binding 0.7425 Moderately Informative Inherited
Molecular Function (MF) organic cyclic compound binding 0.7649 Moderately Informative Inherited
Molecular Function (MF) protein binding 0.8739 Moderately Informative Inherited
Molecular Function (MF) anion binding 0.04218 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.02031 Moderately Informative Inherited
Molecular Function (MF) carbon-carbon lyase activity 0 Informative Direct
Molecular Function (MF) enzyme regulator activity 0.000004333 Informative Direct
Molecular Function (MF) cofactor binding 0.0000561 Informative Direct
Molecular Function (MF) isomerase activity 0.000156 Informative Direct
Molecular Function (MF) protein dimerization activity 0.001189 Informative Inherited
Molecular Function (MF) identical protein binding 0.002494 Informative Inherited
Molecular Function (MF) carboxy-lyase activity 0.0000000002617 Highly Informative Direct
Molecular Function (MF) enzyme activator activity 0.0000000156 Highly Informative Direct
Molecular Function (MF) vitamin binding 0.00000008823 Highly Informative Direct
Molecular Function (MF) protein homodimerization activity 0.0001199 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.8093 Least Informative Inherited
Cellular Component (CC) perinuclear region of cytoplasm 0.0002544 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Lyases0Least InformativeDirect
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Carboxy-lyases0Moderately InformativeDirect
Enzyme Commission (EC)Racemases and epimerases0InformativeDirect
Enzyme Commission (EC)Acting on amino acids and derivatives0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0.1161InformativeInherited
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationIsomerase0InformativeDirect
Post-translational modificationDecarboxylase0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a PLP-binding barrel domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]