SUPERFAMILY 1.75 HMM library and genome assignments server

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Class I glutamine amidotransferases (GAT) family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Flavodoxin-like [ 52171] (15)
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (9)
Family:   Class I glutamine amidotransferases (GAT) [ 52318] (11)


Family statistics
Genomes (3,220) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 18,077 95,919 26
Proteins 18,070 95,909 26


Gene Ontology (high-quality)

(
show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular aromatic compound metabolic process0.000000000054830Least InformativeDirect
Biological Process (BP)biosynthetic process0.000000014530Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.00000000000020950Least InformativeDirect
Biological Process (BP)single-organism metabolic process0.0000000000012230Least InformativeDirect
Biological Process (BP)single-organism cellular process0.00000028960Least InformativeDirect
Biological Process (BP)heterocycle metabolic process0.0000000000032410Least InformativeDirect
Biological Process (BP)organic cyclic compound metabolic process0.000000000089540Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.0000000091810Least InformativeDirect
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.000000000000025160Moderately InformativeDirect
Biological Process (BP)aromatic compound biosynthetic process0.000000000000004450Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process0.000063330Moderately InformativeDirect
Biological Process (BP)small molecule biosynthetic process0.000000063980.0003317Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.00000000000020030Moderately InformativeDirect
Biological Process (BP)carboxylic acid metabolic process0.85420.3299Moderately InformativeInherited
Biological Process (BP)phosphate-containing compound metabolic process0.29560Moderately InformativeInherited
Biological Process (BP)carbohydrate derivative metabolic process0.49020.000000007724Moderately InformativeInherited
Biological Process (BP)cellular amide metabolic process0.24090.9712Moderately InformativeInherited
Biological Process (BP)cofactor metabolic process0.0024810.02451Moderately InformativeInherited
Biological Process (BP)organophosphate metabolic process0.67880.00000000000005617Moderately InformativeInherited
Biological Process (BP)nucleobase-containing small molecule metabolic process0.66290Moderately InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.000000013710.0000000136InformativeDirect
Biological Process (BP)cellular biogenic amine metabolic process0.0000000000036650InformativeDirect
Biological Process (BP)cellular amino acid biosynthetic process0.00000054540.000004036InformativeDirect
Biological Process (BP)coenzyme biosynthetic process0.049080.03641InformativeInherited
Biological Process (BP)pyridine-containing compound metabolic process0.008350.1128InformativeInherited
Biological Process (BP)nucleoside phosphate biosynthetic process0.48370.0000000000001394InformativeInherited
Biological Process (BP)ribose phosphate biosynthetic process0.0031120InformativeInherited
Biological Process (BP)vitamin metabolic process0.098140.1997InformativeInherited
Biological Process (BP)alpha-amino acid metabolic process0.0000000000048540.003449InformativeInherited
Biological Process (BP)purine-containing compound biosynthetic process0.23580.000000258InformativeInherited
Biological Process (BP)folic acid-containing compound metabolic process0.00000000005980.0000000000003904Highly InformativeDirect
Biological Process (BP)aromatic amino acid family metabolic process0.000098760.000000002891Highly InformativeDirect
Biological Process (BP)amine biosynthetic process0.00000021730.000000005933Highly InformativeDirect
Biological Process (BP)indole-containing compound biosynthetic process0.00000000095240.0000000000433Highly InformativeDirect
Biological Process (BP)pteridine-containing compound biosynthetic process0.000011330.00003219Highly InformativeDirect
Biological Process (BP)vitamin B6 metabolic process0.00000039510.00000001842Highly InformativeDirect
Biological Process (BP)imidazole-containing compound metabolic process0.000000009150.0000000005044Highly InformativeDirect
Biological Process (BP)cellular modified amino acid biosynthetic process0.00086480.01284Highly InformativeInherited
Biological Process (BP)indolalkylamine metabolic process0.096870.0003867Highly InformativeInherited
Molecular Function (MF)transferase activity0.39331Least InformativeInherited
Molecular Function (MF)lyase activity0.0000077470.0006465Moderately InformativeDirect
Molecular Function (MF)carbon-carbon lyase activity0.000016880.00000001609InformativeDirect
Molecular Function (MF)ligase activity0.0000054270InformativeDirect
Molecular Function (MF)transferase activity, transferring glycosyl groups0.0021110.0001603InformativeInherited
Molecular Function (MF)transaminase activity0.0000023890.000000001342Highly InformativeDirect
Molecular Function (MF)transferase activity, transferring pentosyl groups0.000000025430.0000000001422Highly InformativeDirect
Molecular Function (MF)oxo-acid-lyase activity00Highly InformativeDirect
Molecular Function (MF)ligase activity, forming carbon-nitrogen bonds0.000000000024410Highly InformativeDirect

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0 Least Informative Direct
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) phosphate-containing compound metabolic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate metabolic process 0.00000000000005617 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.0003317 Moderately Informative Direct
Biological Process (BP) nucleobase-containing small molecule metabolic process 0 Moderately Informative Direct
Biological Process (BP) carbohydrate derivative metabolic process 0.000000007724 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) regulation of response to stimulus 1 Moderately Informative Inherited
Biological Process (BP) regulation of signaling 1 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) carboxylic acid metabolic process 0.3299 Moderately Informative Inherited
Biological Process (BP) regulation of cell communication 1 Moderately Informative Inherited
Biological Process (BP) anatomical structure morphogenesis 1 Moderately Informative Inherited
Biological Process (BP) cellular amide metabolic process 0.9712 Moderately Informative Inherited
Biological Process (BP) cofactor metabolic process 0.02451 Moderately Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.0000000136 Informative Direct
Biological Process (BP) cellular biogenic amine metabolic process 0 Informative Direct
Biological Process (BP) cellular amino acid biosynthetic process 0.000004036 Informative Direct
Biological Process (BP) ribonucleoside monophosphate metabolic process 0.00000002404 Informative Direct
Biological Process (BP) ribose phosphate biosynthetic process 0 Informative Direct
Biological Process (BP) purine-containing compound biosynthetic process 0.000000258 Informative Direct
Biological Process (BP) pyrimidine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) nucleoside phosphate biosynthetic process 0.0000000000001394 Informative Direct
Biological Process (BP) glycosyl compound metabolic process 0.0000000007059 Informative Direct
Biological Process (BP) coenzyme biosynthetic process 0.03641 Informative Inherited
Biological Process (BP) purine ribonucleotide metabolic process 1 Informative Inherited
Biological Process (BP) pyridine-containing compound metabolic process 0.1128 Informative Inherited
Biological Process (BP) circulatory system development 0.2053 Informative Inherited
Biological Process (BP) nervous system development 1 Informative Inherited
Biological Process (BP) nucleoside triphosphate metabolic process 1 Informative Inherited
Biological Process (BP) purine nucleoside monophosphate metabolic process 0.9871 Informative Inherited
Biological Process (BP) vitamin metabolic process 0.1997 Informative Inherited
Biological Process (BP) alpha-amino acid metabolic process 0.003449 Informative Inherited
Biological Process (BP) anatomical structure formation involved in morphogenesis 0.4374 Informative Inherited
Biological Process (BP) pyrimidine nucleotide metabolic process 0.000001954 Highly Informative Direct
Biological Process (BP) indolalkylamine metabolic process 0.0003867 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.0000000000003904 Highly Informative Direct
Biological Process (BP) aromatic amino acid family metabolic process 0.000000002891 Highly Informative Direct
Biological Process (BP) nucleobase metabolic process 0 Highly Informative Direct
Biological Process (BP) purine nucleoside monophosphate biosynthetic process 0.0001209 Highly Informative Direct
Biological Process (BP) ribonucleoside monophosphate biosynthetic process 0.000000787 Highly Informative Direct
Biological Process (BP) amine biosynthetic process 0.000000005933 Highly Informative Direct
Biological Process (BP) indole-containing compound biosynthetic process 0.0000000000433 Highly Informative Direct
Biological Process (BP) pteridine-containing compound biosynthetic process 0.00003219 Highly Informative Direct
Biological Process (BP) vitamin B6 metabolic process 0.00000001842 Highly Informative Direct
Biological Process (BP) imidazole-containing compound metabolic process 0.0000000005044 Highly Informative Direct
Biological Process (BP) regulation of cellular response to growth factor stimulus 0.0007792 Highly Informative Direct
Biological Process (BP) glycosyl compound biosynthetic process 0.00000009687 Highly Informative Direct
Biological Process (BP) camera-type eye development 0.004528 Highly Informative Inherited
Biological Process (BP) cellular modified amino acid biosynthetic process 0.01284 Highly Informative Inherited
Biological Process (BP) ribonucleoside metabolic process 0.05677 Highly Informative Inherited
Biological Process (BP) purine nucleoside metabolic process 0.6299 Highly Informative Inherited
Biological Process (BP) nucleoside triphosphate biosynthetic process 0.009398 Highly Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.07249 Highly Informative Inherited
Molecular Function (MF) transferase activity 1 Least Informative Inherited
Molecular Function (MF) hydrolase activity 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0.0006465 Moderately Informative Direct
Molecular Function (MF) peptidase activity 0.000541 Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0.0001603 Informative Direct
Molecular Function (MF) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.0000000465 Informative Direct
Molecular Function (MF) carbon-carbon lyase activity 0.00000001609 Informative Direct
Molecular Function (MF) ligase activity 0 Informative Direct
Molecular Function (MF) exopeptidase activity 0.00000002003 Highly Informative Direct
Molecular Function (MF) transaminase activity 0.000000001342 Highly Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0.0000000001422 Highly Informative Direct
Molecular Function (MF) oxo-acid-lyase activity 0 Highly Informative Direct
Molecular Function (MF) ligase activity, forming carbon-nitrogen bonds 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases1Moderately InformativeInherited
Enzyme Commission (EC)Carboxy-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Oxo-acid-lyases0InformativeDirect
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.00000001655InformativeDirect
Enzyme Commission (EC)Interconverting aldoses and ketoses, and related c1InformativeInherited
Enzyme Commission (EC)Transferring nitrogenous groups1InformativeInherited
Enzyme Commission (EC)Transaminases (aminotransferases)1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processAmino-acid biosynthesis0InformativeDirect
Biological processPyrimidine biosynthesis0Highly InformativeDirect
Biological processPurine biosynthesis0Highly InformativeDirect
Biological processArginine biosynthesis0Highly InformativeDirect
Biological processHistidine biosynthesis0Highly InformativeDirect
Biological processAromatic amino acid biosynthesis1Highly InformativeInherited
DomainGlutamine amidotransferase0Highly InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMagnesium0Moderately InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationLyase0Moderately InformativeDirect
Post-translational modificationLigase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 35 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]