SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Motor proteins family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   P-loop containing nucleoside triphosphate hydrolases [ 52539]
Superfamily:   P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
Family:   Motor proteins [ 52641] (4)


Family statistics
Genomes (505) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,596 66,829 46
Proteins 22,395 66,366 46


Enzyme Commission (EC)

(
show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-serine/threonine kinases0.00000000008303Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0.000000000009639InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.2359Least InformativeInherited
Disease Ontology (DO)inner ear disease0.00004729Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.2088Least InformativeInherited
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.006146Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic sensory system morphology0.2835Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear hair cell morphology0.01976InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system electrophysiology0.5096InformativeInherited
Mammalian Phenotype (MP)abnormal hearing physiology0.8674InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear inner hair cell morphology0.005323Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hearing electrophysiology0.4089Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.000006802Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.0006458Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.165Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.4782Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.00002299Moderately InformativeDirect
Worm Phenotype (WP)cell cycle variant0.001723Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.004788Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.01709Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.02838Moderately InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.1338Moderately InformativeInherited
Worm Phenotype (WP)germ cell development variant0.9043Moderately InformativeInherited
Worm Phenotype (WP)cytoskeleton organization biogenesis variant0.0000000004867InformativeDirect
Worm Phenotype (WP)embryonic cell organization biogenesis variant0.000000263InformativeDirect
Worm Phenotype (WP)axon outgrowth variant0.000002408InformativeDirect
Worm Phenotype (WP)cytokinesis variant emb0.0002346InformativeDirect
Worm Phenotype (WP)nervous system physiology variant0.000254InformativeDirect
Worm Phenotype (WP)meiotic chromosome organization variant0.1734InformativeInherited
Worm Phenotype (WP)axon morphology variant0.000000034Highly InformativeDirect
Worm Phenotype (WP)X chromosome nondisjunction0.00000159Highly InformativeDirect
Worm Phenotype (WP)cleavage furrow defective early emb0.000002754Highly InformativeDirect
Worm Phenotype (WP)muscle arm development defective0.000009942Highly InformativeDirect
Worm Phenotype (WP)neuron physiology variant0.00002554Highly InformativeDirect
Worm Phenotype (WP)pronucleus centrosomes defective early emb0.0004421Highly InformativeDirect
Worm Phenotype (WP)mechanosensation variant0.001384Highly InformativeInherited
Worm Phenotype (WP)male mating variant0.007199Highly InformativeInherited
Worm Phenotype (WP)meiosis defective early emb0.0211Highly InformativeInherited
Worm Phenotype (WP)neurite development variant0.8784Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.1354Least InformativeInherited
Fly Phenotype (FP)lethal - all die before end of P-stage0.01156Moderately InformativeInherited
Fly Phenotype (FP)cell cycle defective0.0000185InformativeDirect
Fly Phenotype (FP)lethal - all die before end of first instar larval stage0.0003233InformativeDirect
Fly Phenotype (FP)lethal - all die before end of embryonic stage0.0001291Highly InformativeDirect
Fly Phenotype (FP)sensory perception defective0.04587Highly InformativeInherited

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)gonad0.0003488Moderately InformativeDirect
Fly Anatomy (FA)germline cell0.00003346InformativeDirect
Fly Anatomy (FA)male organism0.0005607InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cavitated compound organ0.03441Least InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.1341Least InformativeInherited
Zebrafish Anatomy (ZA)cell0.2568Least InformativeInherited
Zebrafish Anatomy (ZA)nervous system0.4146Least InformativeInherited
Zebrafish Anatomy (ZA)multi-tissue structure0.6221Least InformativeInherited
Zebrafish Anatomy (ZA)organism subdivision0.7045Least InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.01251Moderately InformativeInherited
Zebrafish Anatomy (ZA)sensory system0.2444Moderately InformativeInherited
Zebrafish Anatomy (ZA)head0.6198Moderately InformativeInherited
Zebrafish Anatomy (ZA)immune system0.122InformativeInherited
Zebrafish Anatomy (ZA)retina0.2387InformativeInherited
Zebrafish Anatomy (ZA)pleuroperitoneal region0.2864InformativeInherited
Zebrafish Anatomy (ZA)epithelial cell0.003977Highly InformativeInherited
Zebrafish Anatomy (ZA)pronephric glomerulus0.01678Highly InformativeInherited
Zebrafish Anatomy (ZA)retinal photoreceptor layer0.03682Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0.9468Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.9562Least InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.6795Moderately InformativeInherited
Xenopus ANatomical entity (XAN)muscle0.7533InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0.00000000009439InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 512 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]