SUPERFAMILY 1.75 HMM library and genome assignments server

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Motor proteins family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   P-loop containing nucleoside triphosphate hydrolases [ 52539]
Superfamily:   P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
Family:   Motor proteins [ 52641] (4)


Family statistics
Genomes (505) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,596 66,829 46
Proteins 22,395 66,366 46


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Protein-serine/threonine kinases0.00000000008303Moderately InformativeDirect
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0.000000000009639InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.2359Least InformativeInherited
Disease Ontology (DO)inner ear disease0.00004729Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.2086Least InformativeInherited
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.006143Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic sensory system morphology0.2835Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear hair cell morphology0.01977InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system electrophysiology0.5095InformativeInherited
Mammalian Phenotype (MP)abnormal hearing physiology0.8674InformativeInherited
Mammalian Phenotype (MP)abnormal cochlear inner hair cell morphology0.005324Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hearing electrophysiology0.4088Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.000006908Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.0006504Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.1666Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.4809Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.00002334Moderately InformativeDirect
Worm Phenotype (WP)cell cycle variant0.001708Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.00477Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.01703Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.02866Moderately InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.1331Moderately InformativeInherited
Worm Phenotype (WP)germ cell development variant0.9041Moderately InformativeInherited
Worm Phenotype (WP)cytoskeleton organization biogenesis variant0.0000000004953InformativeDirect
Worm Phenotype (WP)embryonic cell organization biogenesis variant0.0000002667InformativeDirect
Worm Phenotype (WP)axon outgrowth variant0.000002436InformativeDirect
Worm Phenotype (WP)cytokinesis variant emb0.0002366InformativeDirect
Worm Phenotype (WP)nervous system physiology variant0.0002558InformativeDirect
Worm Phenotype (WP)meiotic chromosome organization variant0.1715InformativeInherited
Worm Phenotype (WP)axon morphology variant0.00000003445Highly InformativeDirect
Worm Phenotype (WP)X chromosome nondisjunction0.000001605Highly InformativeDirect
Worm Phenotype (WP)cleavage furrow defective early emb0.00000278Highly InformativeDirect
Worm Phenotype (WP)muscle arm development defective0.00001001Highly InformativeDirect
Worm Phenotype (WP)neuron physiology variant0.00002567Highly InformativeDirect
Worm Phenotype (WP)pronucleus centrosomes defective early emb0.0004448Highly InformativeDirect
Worm Phenotype (WP)mechanosensation variant0.001384Highly InformativeInherited
Worm Phenotype (WP)male mating variant0.00724Highly InformativeInherited
Worm Phenotype (WP)meiosis defective early emb0.02118Highly InformativeInherited
Worm Phenotype (WP)neurite development variant0.8783Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.1275Least InformativeInherited
Fly Phenotype (FP)lethal - all die before end of P-stage0.01192Moderately InformativeInherited
Fly Phenotype (FP)cell cycle defective0.00001833InformativeDirect
Fly Phenotype (FP)lethal - all die before end of first instar larval stage0.0003321InformativeDirect
Fly Phenotype (FP)lethal - all die before end of embryonic stage0.000134Highly InformativeDirect
Fly Phenotype (FP)sensory perception defective0.04505Highly InformativeInherited

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)gonad0.0003168Moderately InformativeDirect
Fly Anatomy (FA)germline cell0.00003099InformativeDirect
Fly Anatomy (FA)male-specific anatomical entity0.000328InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cavitated compound organ0.03144Least InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.1286Least InformativeInherited
Zebrafish Anatomy (ZA)cell0.2594Least InformativeInherited
Zebrafish Anatomy (ZA)nervous system0.4087Least InformativeInherited
Zebrafish Anatomy (ZA)multi-tissue structure0.6145Least InformativeInherited
Zebrafish Anatomy (ZA)organism subdivision0.6914Least InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.01215Moderately InformativeInherited
Zebrafish Anatomy (ZA)sensory system0.2337Moderately InformativeInherited
Zebrafish Anatomy (ZA)head0.6104Moderately InformativeInherited
Zebrafish Anatomy (ZA)immune system0.1253InformativeInherited
Zebrafish Anatomy (ZA)pleuroperitoneal region0.2868InformativeInherited
Zebrafish Anatomy (ZA)eye0.3843InformativeInherited
Zebrafish Anatomy (ZA)epithelial cell0.004035Highly InformativeInherited
Zebrafish Anatomy (ZA)retinal photoreceptor layer0.03684Highly InformativeInherited
Zebrafish Anatomy (ZA)pronephros0.1225Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0.9468Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.9556Least InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.678Moderately InformativeInherited
Xenopus ANatomical entity (XAN)muscle0.753InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Protein-serine/threonine kinases0.00000000009439InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 512 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]