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RecA protein-like (ATPase-domain) family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   P-loop containing nucleoside triphosphate hydrolases [ 52539]
Superfamily:   P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
Family:   RecA protein-like (ATPase-domain) [ 52670] (17)


Family statistics
Genomes (3,253) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,810 220,760 43
Proteins 22,637 219,710 41


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides1Moderately InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphatase0InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)genetic disease0.005724Moderately InformativeInherited
Disease Ontology (DO)hereditary breast ovarian cancer syndrome0.0000239InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.007088Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.04744Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.05633Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.06606Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.06869Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.1161Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the skeletal system0.1203Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the head0.1346Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.2705Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.3711Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal reproductive system morphology0.001523Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal anterior eye segment morphology0.006671Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.01245Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.01829Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the abdominal organs0.02262Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.04683Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.0658Moderately InformativeInherited
Phenotypic Abnormality (PA)Localized skin lesion0.07634Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.08194Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.08837Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the respiratory system0.107Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the skull0.1104Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of blood and blood-forming tissues0.14Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vasculature0.1453Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1605Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.2273Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.3342Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of immune system physiology0.4757Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.7493Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system0.7514Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lens0.0005133InformativeDirect
Phenotypic Abnormality (PA)Abnormal myocardium morphology0.0005572InformativeDirect
Phenotypic Abnormality (PA)Abnormal thumb morphology0.001207InformativeInherited
Phenotypic Abnormality (PA)Abnormal palate morphology0.002283InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the palpebral fissures0.003349InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the synovia0.004457InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin pigmentation0.005487InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving bones of the extremities0.009196InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.009471InformativeInherited
Phenotypic Abnormality (PA)Abnormal finger phalanx morphology0.01131InformativeInherited
Phenotypic Abnormality (PA)Abnormal breast morphology0.01493InformativeInherited
Phenotypic Abnormality (PA)Neoplasm of the genitourinary tract0.01528InformativeInherited
Phenotypic Abnormality (PA)Abnormality of prenatal development or birth0.01932InformativeInherited
Phenotypic Abnormality (PA)Abnormality of toe0.02367InformativeInherited
Phenotypic Abnormality (PA)Neoplasm of the gastrointestinal tract0.02746InformativeInherited
Phenotypic Abnormality (PA)Abnormality of pelvic girdle bone morphology0.02954InformativeInherited
Phenotypic Abnormality (PA)Abnormality of lower limb joint0.04427InformativeInherited
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.04838InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart valve morphology0.05341InformativeInherited
Phenotypic Abnormality (PA)Anorectal anomaly0.05839InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper respiratory tract0.0657InformativeInherited
Phenotypic Abnormality (PA)Recurrent infections0.08522InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the pancreas0.1011InformativeInherited
Phenotypic Abnormality (PA)Abnormal upper limb bone morphology0.1174InformativeInherited
Phenotypic Abnormality (PA)Abnormal intestine morphology0.1921InformativeInherited
Phenotypic Abnormality (PA)Abnormality of reproductive system physiology0.1978InformativeInherited
Phenotypic Abnormality (PA)Abnormal systemic arterial morphology0.2163InformativeInherited
Phenotypic Abnormality (PA)Abnormality of calvarial morphology0.5128InformativeInherited
Phenotypic Abnormality (PA)Abnormal testis morphology0.6352InformativeInherited
Phenotypic Abnormality (PA)Prostate neoplasm0.00000459Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the uvula0.0000215Highly InformativeDirect
Phenotypic Abnormality (PA)Triangular shaped phalanges of the hand0.00007597Highly InformativeDirect
Phenotypic Abnormality (PA)Breast carcinoma0.00009583Highly InformativeDirect
Phenotypic Abnormality (PA)High palate0.0001188Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal uterus morphology0.0003879Highly InformativeDirect
Phenotypic Abnormality (PA)Choanal atresia0.0004325Highly InformativeDirect
Phenotypic Abnormality (PA)Hyperpigmentation of the skin0.0004409Highly InformativeDirect
Phenotypic Abnormality (PA)Cranial nerve paralysis0.0007447Highly InformativeDirect
Phenotypic Abnormality (PA)Anemia of inadequate production0.0008264Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal aortic valve morphology0.0008606Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal trachea morphology0.000972Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the ulna0.001409Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anus0.001836Highly InformativeInherited
Phenotypic Abnormality (PA)Cafe-au-lait spot0.001977Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the radius0.003399Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the phalanges of the toes0.01158Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the ureter0.01452Highly InformativeInherited
Phenotypic Abnormality (PA)Hematological neoplasm0.01632Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal esophagus morphology0.02361Highly InformativeInherited
Phenotypic Abnormality (PA)Decreased fertility0.06971Highly InformativeInherited
Phenotypic Abnormality (PA)Ocular anterior segment dysgenesis0.06981Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

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MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09014Least InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.0005923Moderately InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0004205Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.0009547Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.001219Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.01861Least InformativeInherited
Worm Phenotype (WP)cell death variant0.000001802Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.000004745Moderately InformativeDirect
Worm Phenotype (WP)gametogenesis variant0.000008355Moderately InformativeDirect
Worm Phenotype (WP)cell component morphology variant0.00002607Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.0002162Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.0005524Moderately InformativeDirect
Worm Phenotype (WP)feeding behavior variant0.006804Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.01228Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.2129Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.2152Moderately InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.2322Moderately InformativeInherited
Worm Phenotype (WP)diplotene progression during oogenesis variant0.0000002669InformativeDirect
Worm Phenotype (WP)recycling endosome morphology variant0.0000003334InformativeDirect
Worm Phenotype (WP)accumulated germline cell corpses0.0000006265InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.000009051InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00009591InformativeDirect
Worm Phenotype (WP)transgene expression increased0.0001045InformativeDirect
Worm Phenotype (WP)gonad development variant0.0001524InformativeDirect
Worm Phenotype (WP)cell component localization variant0.01092InformativeInherited
Worm Phenotype (WP)meiotic chromosome organization variant0.34InformativeInherited
Worm Phenotype (WP)diplotene region organization variant0.0000000309Highly InformativeDirect
Worm Phenotype (WP)germ cell compartment anucleate0.0000007743Highly InformativeDirect
Worm Phenotype (WP)oocyte septum formation variant0.000002171Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0.000006674Highly InformativeDirect
Worm Phenotype (WP)chromosome condensation variant0.000007623Highly InformativeDirect
Worm Phenotype (WP)lysosome-related organelle morphology variant0.000425Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect
Yeast Phenotype (YP)resistance to chemicals0.6505Least InformativeInherited
Yeast Phenotype (YP)development0Moderately InformativeDirect
Yeast Phenotype (YP)oxidative stress resistance0.000196InformativeDirect
Yeast Phenotype (YP)desiccation resistance0.0004088InformativeDirect
Yeast Phenotype (YP)sexual cycle0.01197InformativeInherited
Yeast Phenotype (YP)sporulation0.00001857Highly InformativeDirect
Yeast Phenotype (YP)alkaline pH resistance0.00007058Highly InformativeDirect
Yeast Phenotype (YP)starvation resistance0.0003333Highly InformativeDirect
Yeast Phenotype (YP)resistance to enzymatic treatment0.0003885Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell cycle defective0.0008237InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)female organism0.03472Moderately InformativeInherited
Fly Anatomy (FA)gonad0.05452Moderately InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.06773Moderately InformativeInherited
Fly Anatomy (FA)egg0.003026InformativeInherited
Fly Anatomy (FA)female germline cyst0.01451InformativeInherited
Fly Anatomy (FA)germline cell0.01835InformativeInherited
Fly Anatomy (FA)cell component0.0196InformativeInherited
Fly Anatomy (FA)dorsal appendage0.0002014Highly InformativeDirect
Fly Anatomy (FA)female germline cell0.0002741Highly InformativeDirect
Fly Anatomy (FA)oocyte0.0005692Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)seed development stage0.00024InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.7703Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Translocases0InformativeDirect
Enzyme Commission (EC)In phosphorus-containing anhydrides0.05347InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphate phosphatase0Highly InformativeDirect
Enzyme Commission (EC)Catalysing the translocation of inorganic cations1Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 512 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]