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RecA protein-like (ATPase-domain) family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   P-loop containing nucleoside triphosphate hydrolases [ 52539]
Superfamily:   P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
Family:   RecA protein-like (ATPase-domain) [ 52670] (17)


Family statistics
Genomes (3,253) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,810 220,760 43
Proteins 22,637 219,710 41


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides1Moderately InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphatase0InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)genetic disease0.005723Moderately InformativeInherited
Disease Ontology (DO)hereditary breast ovarian cancer syndrome0.00002391InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.03804Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.1203Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.1384Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.1431Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.1912Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.2423Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.245Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the immune system0.4324Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.5142Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.6524Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal reproductive system morphology0.005807Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.006439Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal anterior eye segment morphology0.01428Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.04132Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.06784Moderately InformativeInherited
Phenotypic Abnormality (PA)Localized skin lesion0.07499Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.07845Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.0827Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system physiology0.1388Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal vascular morphology0.1418Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1703Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of blood and blood-forming tissues0.2319Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal respiratory system morphology0.233Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.2643Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.3741Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of immune system physiology0.5144Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.7493Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the hand0.7754Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal myocardium morphology0.001368InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the hip joint0.001516InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.00415InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the palpebral fissures0.006591InformativeInherited
Phenotypic Abnormality (PA)Abnormal palate morphology0.006612InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin pigmentation0.007817InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving bones of the extremities0.01898InformativeInherited
Phenotypic Abnormality (PA)Abnormal finger phalanx morphology0.02001InformativeInherited
Phenotypic Abnormality (PA)Abnormal cellular physiology0.02404InformativeInherited
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.03699InformativeInherited
Phenotypic Abnormality (PA)Anorectal anomaly0.04846InformativeInherited
Phenotypic Abnormality (PA)Abnormality of prenatal development or birth0.05172InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper respiratory tract0.05959InformativeInherited
Phenotypic Abnormality (PA)Abnormality of toe0.08009InformativeInherited
Phenotypic Abnormality (PA)Anemia0.08408InformativeInherited
Phenotypic Abnormality (PA)Recurrent infections0.1275InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.1385InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the uterus0.1462InformativeInherited
Phenotypic Abnormality (PA)Abnormality of reproductive system physiology0.1894InformativeInherited
Phenotypic Abnormality (PA)Abnormal intestine morphology0.2066InformativeInherited
Phenotypic Abnormality (PA)Abnormal systemic arterial morphology0.2166InformativeInherited
Phenotypic Abnormality (PA)Abnormality of calvarial morphology0.5545InformativeInherited
Phenotypic Abnormality (PA)Abnormality of male external genitalia0.9691InformativeInherited
Phenotypic Abnormality (PA)Breast carcinoma0.000004586Highly InformativeDirect
Phenotypic Abnormality (PA)Prostate neoplasm0.00001436Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the uvula0.00004924Highly InformativeDirect
Phenotypic Abnormality (PA)Hydroureter0.00005196Highly InformativeDirect
Phenotypic Abnormality (PA)Triangular shaped phalanges of the hand0.0001274Highly InformativeDirect
Phenotypic Abnormality (PA)Decreased fertility in males0.0001539Highly InformativeDirect
Phenotypic Abnormality (PA)High palate0.0004219Highly InformativeDirect
Phenotypic Abnormality (PA)Azoospermia0.0006248Highly InformativeDirect
Phenotypic Abnormality (PA)Choanal atresia0.0006881Highly InformativeDirect
Phenotypic Abnormality (PA)Hyperpigmentation of the skin0.0007444Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal trachea morphology0.001332Highly InformativeInherited
Phenotypic Abnormality (PA)Anemia of inadequate production0.001709Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal thumb morphology0.001804Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the ulna0.001834Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anus0.002435Highly InformativeInherited
Phenotypic Abnormality (PA)Cafe-au-lait spot0.002523Highly InformativeInherited
Phenotypic Abnormality (PA)Syndactyly0.002524Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the radius0.004521Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the phalanges of the toes0.01486Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal esophagus morphology0.0197Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the penis0.02713Highly InformativeInherited
Phenotypic Abnormality (PA)Hematological neoplasm0.03626Highly InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia affecting the eye0.04501Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the small intestine0.04648Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the amniotic fluid0.07679Highly InformativeInherited
Phenotypic Abnormality (PA)Ocular anterior segment dysgenesis0.07725Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09015Least InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.0005902Moderately InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0004937Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.00149Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.002015Least InformativeInherited
Worm Phenotype (WP)cell cycle variant0.0000006955Moderately InformativeDirect
Worm Phenotype (WP)cell organization biogenesis variant0.000001355Moderately InformativeDirect
Worm Phenotype (WP)cell death variant0.000002052Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.000005847Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.000008097Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.0002287Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.0005927Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.0135Moderately InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant0.1634Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.2067Moderately InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.2436Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.3699Moderately InformativeInherited
Worm Phenotype (WP)diplotene progression during oogenesis variant0.0000002755InformativeDirect
Worm Phenotype (WP)accumulated germline cell corpses0.0000006487InformativeDirect
Worm Phenotype (WP)vesicle organization variant0.0000007662InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.000009896InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.0001123InformativeDirect
Worm Phenotype (WP)transgene expression increased0.0001491InformativeDirect
Worm Phenotype (WP)gonad development variant0.0001659InformativeDirect
Worm Phenotype (WP)cell component localization variant0.008241InformativeInherited
Worm Phenotype (WP)mitosis variant0.02767InformativeInherited
Worm Phenotype (WP)meiotic chromosome organization variant0.3283InformativeInherited
Worm Phenotype (WP)diplotene region organization variant0.00000003146Highly InformativeDirect
Worm Phenotype (WP)germ cell compartment anucleate0.0000007712Highly InformativeDirect
Worm Phenotype (WP)oocyte septum formation variant0.000002187Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0.000007345Highly InformativeDirect
Worm Phenotype (WP)chromosome condensation variant0.000007744Highly InformativeDirect
Worm Phenotype (WP)lysosome-related organelle morphology variant0.0001375Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect
Yeast Phenotype (YP)resistance to chemicals0.6505Least InformativeInherited
Yeast Phenotype (YP)development0Moderately InformativeDirect
Yeast Phenotype (YP)oxidative stress resistance0.000196InformativeDirect
Yeast Phenotype (YP)desiccation resistance0.0004088InformativeDirect
Yeast Phenotype (YP)sexual cycle0.01197InformativeInherited
Yeast Phenotype (YP)sporulation0.00001857Highly InformativeDirect
Yeast Phenotype (YP)alkaline pH resistance0.00007058Highly InformativeDirect
Yeast Phenotype (YP)starvation resistance0.0003333Highly InformativeDirect
Yeast Phenotype (YP)resistance to enzymatic treatment0.0003885Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell cycle defective0.0008224InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)female-specific anatomical entity0.02694Moderately InformativeInherited
Fly Anatomy (FA)gonad0.05123Moderately InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.06263Moderately InformativeInherited
Fly Anatomy (FA)egg0.002764InformativeInherited
Fly Anatomy (FA)female germline cyst0.01358InformativeInherited
Fly Anatomy (FA)germline cell0.01752InformativeInherited
Fly Anatomy (FA)ovariole0.02162InformativeInherited
Fly Anatomy (FA)cell component0.02511InformativeInherited
Fly Anatomy (FA)dorsal appendage0.0001888Highly InformativeDirect
Fly Anatomy (FA)female germline cell0.0002554Highly InformativeDirect
Fly Anatomy (FA)oocyte0.0005305Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)seed development stage0.00024InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.6588Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Translocases0InformativeDirect
Enzyme Commission (EC)In phosphorus-containing anhydrides0.05161InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphate phosphatase0Highly InformativeDirect
Enzyme Commission (EC)Catalysing the translocation of inorganic cations1Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 512 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]