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RecA protein-like (ATPase-domain) family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   P-loop containing nucleoside triphosphate hydrolases [ 52539]
Superfamily:   P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
Family:   RecA protein-like (ATPase-domain) [ 52670] (17)


Family statistics
Genomes (3,253) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,810 220,760 43
Proteins 22,637 219,710 41


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides1Moderately InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphatase0InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)genetic disease0.005728Moderately InformativeInherited
Disease Ontology (DO)hereditary breast ovarian cancer syndrome0.00002394InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.008815Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.05316Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.06687Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.07497Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.08874Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.1246Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.1335Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.296Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.3998Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.6461Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal reproductive system morphology0.00188Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal anterior eye segment morphology0.006935Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.01551Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.02122Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.04794Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.06431Moderately InformativeInherited
Phenotypic Abnormality (PA)Localized skin lesion0.07353Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.08939Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal skull morphology0.1196Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the respiratory system0.1281Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system physiology0.1453Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal vascular morphology0.1499Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1635Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of blood and blood-forming tissues0.1655Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.274Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.3574Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of immune system physiology0.4953Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.7292Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the hand0.7595Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Cardiomyopathy0.0005284InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lens0.0005646InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the hip joint0.0009963InformativeDirect
Phenotypic Abnormality (PA)Abnormal thumb morphology0.001196InformativeInherited
Phenotypic Abnormality (PA)Abnormal palate morphology0.002907InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the palpebral fissures0.003189InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin pigmentation0.00548InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.009426InformativeInherited
Phenotypic Abnormality (PA)Abnormal finger phalanx morphology0.01114InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the ureter0.01324InformativeInherited
Phenotypic Abnormality (PA)Neoplasm of the genitourinary tract0.01613InformativeInherited
Phenotypic Abnormality (PA)Abnormal breast morphology0.01732InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the penis0.01734InformativeInherited
Phenotypic Abnormality (PA)Abnormal cellular physiology0.02294InformativeInherited
Phenotypic Abnormality (PA)Abnormality of prenatal development or birth0.02629InformativeInherited
Phenotypic Abnormality (PA)Neoplasm of the gastrointestinal tract0.03181InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia of the extremities0.03361InformativeInherited
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.04304InformativeInherited
Phenotypic Abnormality (PA)Abnormal testis morphology0.04645InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart valve morphology0.05081InformativeInherited
Phenotypic Abnormality (PA)Anorectal anomaly0.05706InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper respiratory tract0.05718InformativeInherited
Phenotypic Abnormality (PA)Abnormality of toe0.06752InformativeInherited
Phenotypic Abnormality (PA)Recurrent infections0.0946InformativeInherited
Phenotypic Abnormality (PA)Abnormal upper limb bone morphology0.1109InformativeInherited
Phenotypic Abnormality (PA)Abnormality of reproductive system physiology0.1852InformativeInherited
Phenotypic Abnormality (PA)Abnormal intestine morphology0.1954InformativeInherited
Phenotypic Abnormality (PA)Abnormal systemic arterial morphology0.2189InformativeInherited
Phenotypic Abnormality (PA)Abnormality of calvarial morphology0.5404InformativeInherited
Phenotypic Abnormality (PA)Prostate neoplasm0.000005191Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the uvula0.00002107Highly InformativeDirect
Phenotypic Abnormality (PA)Hydroureter0.00003794Highly InformativeDirect
Phenotypic Abnormality (PA)Triangular shaped phalanges of the hand0.00007719Highly InformativeDirect
Phenotypic Abnormality (PA)Breast carcinoma0.00008908Highly InformativeDirect
Phenotypic Abnormality (PA)High palate0.0001702Highly InformativeDirect
Phenotypic Abnormality (PA)Azoospermia0.0004081Highly InformativeDirect
Phenotypic Abnormality (PA)Choanal atresia0.0004306Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal uterus morphology0.0004761Highly InformativeDirect
Phenotypic Abnormality (PA)Hyperpigmentation of the skin0.0004781Highly InformativeDirect
Phenotypic Abnormality (PA)Cranial nerve paralysis0.0007144Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal aortic valve morphology0.0009136Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal trachea morphology0.0009513Highly InformativeDirect
Phenotypic Abnormality (PA)Anemia of inadequate production0.001063Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the ulna0.001324Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anus0.001729Highly InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of the testes0.001892Highly InformativeInherited
Phenotypic Abnormality (PA)Cafe-au-lait spot0.002036Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the radius0.003216Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the phalanges of the toes0.0119Highly InformativeInherited
Phenotypic Abnormality (PA)Hematological neoplasm0.01671Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal esophagus morphology0.02288Highly InformativeInherited
Phenotypic Abnormality (PA)Decreased fertility0.0659Highly InformativeInherited
Phenotypic Abnormality (PA)Ocular anterior segment dysgenesis0.0748Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the amniotic fluid0.09239Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

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MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09014Least InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.0005923Moderately InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.0003765Least InformativeDirect
Worm Phenotype (WP)cell development variant0.000513Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant0.000992Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.001569Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.001569Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.02038Least InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.00000126Moderately InformativeDirect
Worm Phenotype (WP)cell death variant0.000002016Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.000008505Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.000009393Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.00001214Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.0002225Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.0005688Moderately InformativeDirect
Worm Phenotype (WP)feeding behavior variant0.006381Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.01249Moderately InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant0.1208Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.1941Moderately InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.2633Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.3814Moderately InformativeInherited
Worm Phenotype (WP)diplotene progression during oogenesis variant0.0000002759InformativeDirect
Worm Phenotype (WP)vesicle morphology variant0.0000005814InformativeDirect
Worm Phenotype (WP)accumulated germline cell corpses0.0000006468InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.000009329InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00009731InformativeDirect
Worm Phenotype (WP)transgene expression increased0.0001356InformativeDirect
Worm Phenotype (WP)gonad development variant0.0001566InformativeDirect
Worm Phenotype (WP)cell component localization variant0.007942InformativeInherited
Worm Phenotype (WP)mitosis variant0.02169InformativeInherited
Worm Phenotype (WP)meiotic chromosome organization variant0.2184InformativeInherited
Worm Phenotype (WP)diplotene region organization variant0.00000003195Highly InformativeDirect
Worm Phenotype (WP)germ cell compartment anucleate0.0000007977Highly InformativeDirect
Worm Phenotype (WP)oocyte septum formation variant0.000002236Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0.000006872Highly InformativeDirect
Worm Phenotype (WP)chromosome condensation variant0.00000785Highly InformativeDirect
Worm Phenotype (WP)lysosome-related organelle morphology variant0.0001297Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect
Yeast Phenotype (YP)resistance to chemicals0.6505Least InformativeInherited
Yeast Phenotype (YP)development0Moderately InformativeDirect
Yeast Phenotype (YP)oxidative stress resistance0.000196InformativeDirect
Yeast Phenotype (YP)desiccation resistance0.0004088InformativeDirect
Yeast Phenotype (YP)sexual cycle0.01197InformativeInherited
Yeast Phenotype (YP)sporulation0.00001857Highly InformativeDirect
Yeast Phenotype (YP)alkaline pH resistance0.00007058Highly InformativeDirect
Yeast Phenotype (YP)starvation resistance0.0003333Highly InformativeDirect
Yeast Phenotype (YP)resistance to enzymatic treatment0.0003885Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell cycle defective0.0008193InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)female organism0.03464Moderately InformativeInherited
Fly Anatomy (FA)gonad0.05528Moderately InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.06764Moderately InformativeInherited
Fly Anatomy (FA)egg0.003024InformativeInherited
Fly Anatomy (FA)female germline cyst0.01463InformativeInherited
Fly Anatomy (FA)germline cell0.01876InformativeInherited
Fly Anatomy (FA)cell component0.02084InformativeInherited
Fly Anatomy (FA)dorsal appendage0.0002098Highly InformativeDirect
Fly Anatomy (FA)female germline cell0.0002743Highly InformativeDirect
Fly Anatomy (FA)oocyte0.0005713Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)seed development stage0.00024InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.6585Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Translocases0InformativeDirect
Enzyme Commission (EC)In phosphorus-containing anhydrides0.05331InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphate phosphatase0Highly InformativeDirect
Enzyme Commission (EC)Catalysing the translocation of inorganic cations1Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 512 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]