SUPERFAMILY 1.75 HMM library and genome assignments server

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ITPase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Anticodon-binding domain-like [ 52953] (6)
Superfamily:   ITPase-like [ 52972] (3)
Families:   ITPase (Ham1) [ 52973] (4)
  Maf-like [ 52976] (2)
  YjjX-like [ 110621] (2)


Superfamily statistics
Genomes (3,129) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 7,574 42,658 12
Proteins 7,517 42,342 12


Functional annotation
General category Other
Detailed category Unknown function

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-quality)

(show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)cellular nitrogen compound metabolic process0.84691Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.82361Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.68070.9384Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process0.67630.9516Least InformativeInherited
Biological Process (BP)single-organism metabolic process11Least InformativeInherited
Biological Process (BP)single-organism cellular process11Least InformativeInherited
Biological Process (BP)single-organism catabolic process0.041570.02045Moderately InformativeInherited
Biological Process (BP)cellular catabolic process0.12760.1782Moderately InformativeInherited
Biological Process (BP)organic substance catabolic process0.2430.2433Moderately InformativeInherited
Biological Process (BP)nucleoside phosphate metabolic process0.003260.001375Moderately InformativeInherited
Biological Process (BP)nucleobase-containing compound catabolic process0.0000052350.00001002InformativeDirect
Biological Process (BP)organophosphate catabolic process0.00000012370.00000001706InformativeDirect
Biological Process (BP)nucleoside triphosphate catabolic process0.000000042370.000000001184Highly InformativeDirect
Molecular Function (MF)hydrolase activity00Least InformativeDirect
Molecular Function (MF)hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides00Moderately InformativeDirect
Molecular Function (MF)nucleoside-triphosphate diphosphatase activity0.0029710.0000008576Highly InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular nitrogen compound metabolic process 1 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.9384 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 0.9516 Least Informative Inherited
Biological Process (BP) single-organism metabolic process 1 Least Informative Inherited
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) single-organism catabolic process 0.02045 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.1782 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.2433 Moderately Informative Inherited
Biological Process (BP) nucleoside phosphate metabolic process 0.001375 Moderately Informative Inherited
Biological Process (BP) nucleobase-containing compound catabolic process 0.00001002 Informative Direct
Biological Process (BP) organophosphate catabolic process 0.00000001706 Informative Direct
Biological Process (BP) nucleoside triphosphate catabolic process 0.000000001184 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0 Moderately Informative Direct
Molecular Function (MF) nucleoside-triphosphate diphosphatase activity 0.0000008576 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processNucleotide metabolism0Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionMetal-binding0Least InformativeDirect
Molecular functionMagnesium0Least InformativeDirect
Molecular functionManganese0Moderately InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a ITPase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 10 hidden Markov models representing the ITPase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]