SUPERFAMILY 1.75 HMM library and genome assignments server

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GABA-aminotransferase-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   PLP-dependent transferase-like [ 53382] (3)
Superfamily:   PLP-dependent transferases [ 53383] (9)
Family:   GABA-aminotransferase-like [ 53417] (16)


Family statistics
Genomes (3,238) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 31,734 182,780 54
Proteins 31,688 182,661 54


Gene Ontology (high-quality)

(
show details)
GO termFDR (singleton)FDR (all)SDFO levelAnnotation (direct or inherited)
Biological Process (BP)biosynthetic process0.000000000030390Least InformativeDirect
Biological Process (BP)single-organism metabolic process00Least InformativeDirect
Biological Process (BP)single-organism cellular process0.000000000053540.000000000000109Least InformativeDirect
Biological Process (BP)organonitrogen compound metabolic process0.000000000092430Least InformativeDirect
Biological Process (BP)cellular nitrogen compound metabolic process0.22170.5314Least InformativeInherited
Biological Process (BP)heterocycle metabolic process0.014970.4253Least InformativeInherited
Biological Process (BP)cellular aromatic compound metabolic process11Least InformativeInherited
Biological Process (BP)organic cyclic compound metabolic process0.056420.5396Least InformativeInherited
Biological Process (BP)primary metabolic process11Least InformativeInherited
Biological Process (BP)macromolecule metabolic process11Least InformativeInherited
Biological Process (BP)heterocycle biosynthetic process0.000000020010.00000002272Moderately InformativeDirect
Biological Process (BP)carboxylic acid metabolic process00Moderately InformativeDirect
Biological Process (BP)cellular amide metabolic process0.00000000000094950.00000000000005744Moderately InformativeDirect
Biological Process (BP)cellular nitrogen compound biosynthetic process0.00078560.0003714Moderately InformativeDirect
Biological Process (BP)small molecule biosynthetic process0.00000000046650.0000000004492Moderately InformativeDirect
Biological Process (BP)cofactor metabolic process0.000000000086230Moderately InformativeDirect
Biological Process (BP)organic cyclic compound biosynthetic process0.000000097950.0000001367Moderately InformativeDirect
Biological Process (BP)macromolecular complex subunit organization0.067460.2856Moderately InformativeInherited
Biological Process (BP)cellular component biogenesis0.46831Moderately InformativeInherited
Biological Process (BP)aromatic compound biosynthetic process0.95830.8566Moderately InformativeInherited
Biological Process (BP)carbohydrate metabolic process0.99921Moderately InformativeInherited
Biological Process (BP)vitamin metabolic process0.0000000000037060.000000000000001589InformativeDirect
Biological Process (BP)cellular amino acid biosynthetic process0.000096540.00005015InformativeDirect
Biological Process (BP)sulfur compound biosynthetic process0.000000000071740.000000000526InformativeDirect
Biological Process (BP)monocarboxylic acid biosynthetic process0.000051810.00003994InformativeDirect
Biological Process (BP)protein complex assembly0.0068840.01184InformativeInherited
Biological Process (BP)cellular modified amino acid metabolic process0.041510.01692InformativeInherited
Biological Process (BP)alpha-amino acid metabolic process0.21640.003646InformativeInherited
Biological Process (BP)tetrapyrrole metabolic process0.054930.0000000000000282InformativeInherited
Biological Process (BP)polysaccharide metabolic process0.0030420.006975InformativeInherited
Biological Process (BP)carbohydrate biosynthetic process0.37530.6757InformativeInherited
Biological Process (BP)serine family amino acid metabolic process0.00014920.0000000008702Highly InformativeDirect
Biological Process (BP)biotin biosynthetic process00Highly InformativeDirect
Biological Process (BP)folic acid-containing compound metabolic process0.011330.001854Highly InformativeInherited
Biological Process (BP)drug metabolic process0.030460.00004513Highly InformativeInherited
Biological Process (BP)glutamine family amino acid metabolic process0.00035160.004079Highly InformativeInherited
Molecular Function (MF)transferase activity00Least InformativeDirect
Molecular Function (MF)binding0.41711Least InformativeInherited
Molecular Function (MF)small molecule binding00Moderately InformativeDirect
Molecular Function (MF)anion binding0.000000000000040360.00000002452Moderately InformativeDirect
Molecular Function (MF)organic cyclic compound binding0.000000000000064690.000002188Moderately InformativeDirect
Molecular Function (MF)heterocyclic compound binding0.0000000000000097620.000001027Moderately InformativeDirect
Molecular Function (MF)transferase activity, transferring acyl groups0.00005880InformativeDirect
Molecular Function (MF)cofactor binding00InformativeDirect
Molecular Function (MF)isomerase activity0.48380.9243InformativeInherited
Molecular Function (MF)intramolecular transferase activity0.000043340.0003833Highly InformativeDirect
Molecular Function (MF)vitamin binding00Highly InformativeDirect
Molecular Function (MF)acetyltransferase activity0.084431Highly InformativeInherited
Molecular Function (MF)transaminase activity0.45060.0001648Highly InformativeInherited
Cellular Component (CC)intracellular membrane-bounded organelle0.7120.0005638Least InformativeInherited
Cellular Component (CC)cytoplasmic part0.11710.00000000005398Least InformativeInherited

Document: GO annotation of SCOP domains

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.000000000000109 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) cellular nitrogen compound metabolic process 0.5314 Least Informative Inherited
Biological Process (BP) organic cyclic compound metabolic process 0.5396 Least Informative Inherited
Biological Process (BP) biological regulation 1 Least Informative Inherited
Biological Process (BP) cellular aromatic compound metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle metabolic process 0.4253 Least Informative Inherited
Biological Process (BP) response to stimulus 1 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 1 Least Informative Inherited
Biological Process (BP) heterocycle biosynthetic process 0.00000002272 Moderately Informative Direct
Biological Process (BP) carboxylic acid metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular amide metabolic process 0.00000000000005744 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0.0003714 Moderately Informative Direct
Biological Process (BP) small molecule biosynthetic process 0.0000000004492 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.0000001367 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.2856 Moderately Informative Inherited
Biological Process (BP) cellular component biogenesis 1 Moderately Informative Inherited
Biological Process (BP) regulation of biological quality 1 Moderately Informative Inherited
Biological Process (BP) aromatic compound biosynthetic process 0.8566 Moderately Informative Inherited
Biological Process (BP) system development 1 Moderately Informative Inherited
Biological Process (BP) cellular developmental process 1 Moderately Informative Inherited
Biological Process (BP) cellular catabolic process 0.7799 Moderately Informative Inherited
Biological Process (BP) single-organism catabolic process 0.7388 Moderately Informative Inherited
Biological Process (BP) organic substance catabolic process 0.638 Moderately Informative Inherited
Biological Process (BP) lipid metabolic process 0.4374 Moderately Informative Inherited
Biological Process (BP) response to abiotic stimulus 0.6178 Moderately Informative Inherited
Biological Process (BP) response to stress 1 Moderately Informative Inherited
Biological Process (BP) carbohydrate metabolic process 1 Moderately Informative Inherited
Biological Process (BP) vitamin metabolic process 0.000000000000001589 Informative Direct
Biological Process (BP) cellular amino acid biosynthetic process 0.00005015 Informative Direct
Biological Process (BP) tetrapyrrole metabolic process 0.0000000000000282 Informative Direct
Biological Process (BP) pigment metabolic process 0.00002442 Informative Direct
Biological Process (BP) sulfur compound biosynthetic process 0.000000000526 Informative Direct
Biological Process (BP) monocarboxylic acid biosynthetic process 0.00003994 Informative Direct
Biological Process (BP) protein complex assembly 0.01184 Informative Inherited
Biological Process (BP) cellular modified amino acid metabolic process 0.01692 Informative Inherited
Biological Process (BP) lipid biosynthetic process 0.3617 Informative Inherited
Biological Process (BP) organic hydroxy compound metabolic process 0.7947 Informative Inherited
Biological Process (BP) small molecule catabolic process 0.07704 Informative Inherited
Biological Process (BP) organonitrogen compound catabolic process 0.04435 Informative Inherited
Biological Process (BP) alpha-amino acid metabolic process 0.003646 Informative Inherited
Biological Process (BP) polysaccharide metabolic process 0.006975 Informative Inherited
Biological Process (BP) carbohydrate biosynthetic process 0.6757 Informative Inherited
Biological Process (BP) response to hypoxia 0.00005598 Highly Informative Direct
Biological Process (BP) heme biosynthetic process 0.00000002808 Highly Informative Direct
Biological Process (BP) serine family amino acid metabolic process 0.0000000008702 Highly Informative Direct
Biological Process (BP) biotin biosynthetic process 0 Highly Informative Direct
Biological Process (BP) drug metabolic process 0.00004513 Highly Informative Direct
Biological Process (BP) membrane lipid biosynthetic process 0.000000000161 Highly Informative Direct
Biological Process (BP) folic acid-containing compound metabolic process 0.001854 Highly Informative Inherited
Biological Process (BP) polyol metabolic process 0.006829 Highly Informative Inherited
Biological Process (BP) alcohol biosynthetic process 0.6063 Highly Informative Inherited
Biological Process (BP) myeloid cell homeostasis 0.002094 Highly Informative Inherited
Biological Process (BP) myeloid cell differentiation 0.03113 Highly Informative Inherited
Biological Process (BP) monocarboxylic acid catabolic process 0.5896 Highly Informative Inherited
Biological Process (BP) glutamine family amino acid metabolic process 0.004079 Highly Informative Inherited
Molecular Function (MF) transferase activity 0 Least Informative Direct
Molecular Function (MF) binding 1 Least Informative Inherited
Molecular Function (MF) lyase activity 0.00003695 Moderately Informative Direct
Molecular Function (MF) small molecule binding 0 Moderately Informative Direct
Molecular Function (MF) anion binding 0.00000002452 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 0.000002188 Moderately Informative Direct
Molecular Function (MF) heterocyclic compound binding 0.000001027 Moderately Informative Direct
Molecular Function (MF) transferase activity, transferring acyl groups 0 Informative Direct
Molecular Function (MF) cofactor binding 0 Informative Direct
Molecular Function (MF) isomerase activity 0.9243 Informative Inherited
Molecular Function (MF) transaminase activity 0.0001648 Highly Informative Direct
Molecular Function (MF) intramolecular transferase activity 0.0003833 Highly Informative Direct
Molecular Function (MF) vitamin binding 0 Highly Informative Direct
Molecular Function (MF) acetyltransferase activity 1 Highly Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.0005638 Least Informative Direct
Cellular Component (CC) cytoplasmic part 0.00000000005398 Least Informative Direct
Cellular Component (CC) macromolecular complex 1 Least Informative Inherited
Cellular Component (CC) intracellular organelle part 0.7254 Least Informative Inherited
Cellular Component (CC) membrane 1 Least Informative Inherited
Cellular Component (CC) envelope 0.0004018 Moderately Informative Direct
Cellular Component (CC) mitochondrial part 0.0000000000009221 Moderately Informative Direct
Cellular Component (CC) endomembrane system 0.8445 Moderately Informative Inherited
Cellular Component (CC) organelle membrane 0.04954 Moderately Informative Inherited
Cellular Component (CC) intracellular organelle lumen 0.8696 Moderately Informative Inherited
Cellular Component (CC) catalytic complex 0.1194 Moderately Informative Inherited
Cellular Component (CC) mitochondrial matrix 0.0000000000003071 Informative Direct
Cellular Component (CC) organelle subcompartment 0.01339 Informative Inherited
Cellular Component (CC) endoplasmic reticulum part 0.01429 Informative Inherited
Cellular Component (CC) endoplasmic reticulum membrane 0.0001222 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferring one-carbon groups0Least InformativeDirect
Enzyme Commission (EC)Isomerases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0Moderately InformativeDirect
Enzyme Commission (EC)Intramolecular transferases (mutases)0InformativeDirect
Enzyme Commission (EC)Hydroxymethyl-, formyl- and related transferases0InformativeDirect
Enzyme Commission (EC)Transferring nitrogenous groups0InformativeDirect
Enzyme Commission (EC)Transaminases (aminotransferases)0Highly InformativeDirect
Enzyme Commission (EC)Carbon-sulfur lyases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processLipid metabolism0.6206Moderately InformativeInherited
Biological processAntibiotic resistance0InformativeDirect
Biological processAmino-acid biosynthesis0InformativeDirect
Biological processLipid biosynthesis1InformativeInherited
Biological processPorphyrin biosynthesis0Highly InformativeDirect
Biological processLipopolysaccharide biosynthesis0Highly InformativeDirect
Biological processOne-carbon metabolism0Highly InformativeDirect
Biological processChlorophyll biosynthesis0Highly InformativeDirect
Biological processAntibiotic biosynthesis0.000000000000002429Highly InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
DomainTransit peptide0Moderately InformativeDirect
Molecular functionPyridoxal phosphate0Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationIsomerase0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 92 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a PLP-dependent transferases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-quality) · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]