SUPERFAMILY 1.73 HMM library and genome assignments server


Formate dehydrogenase/DMSO reductase, domains 1-3 superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   Formate dehydrogenase/DMSO reductase, domains 1-3 [ 53705]
  contains of two similar intertwined domains related by pseudo dyad; duplication
core: 3 layers: a/b/a; parallel beta-sheet of 5 strands, order 32451
Superfamily:   Formate dehydrogenase/DMSO reductase, domains 1-3 [ 53706]
Families:   Formate dehydrogenase/DMSO reductase, domains 1-3 [ 53707] (10)
  domain 1 (residues 1-55) binds Fe4S4 cluster in FDH but not DMSO reductase


Superfamily statistics
Genomes (983) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 4,558 9,054 18
Proteins 4,558 9,051 18


Functional annotation
General category Metabolism
Detailed category Redox

Function annotation of SCOP domain superfamilies

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 12 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Formate dehydrogenase/DMSO reductase, domains 1-3 domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 12 hidden Markov models representing the Formate dehydrogenase/DMSO reductase, domains 1-3 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]