SUPERFAMILY 1.75 HMM library and genome assignments server

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Phosphate binding protein-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Periplasmic binding protein-like II [ 53849]
Superfamily:   Periplasmic binding protein-like II [ 53850] (3)
Family:   Phosphate binding protein-like [ 53851] (40)


Family statistics
Genomes (3,138) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 43,518 340,414 128
Proteins 43,383 339,826 128


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases0.06758Least InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Acting on polysaccharides0InformativeDirect
Enzyme Commission (EC)Pentosyltransferases0InformativeDirect
Enzyme Commission (EC)Intramolecular transferases (mutases)1InformativeInherited

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.0007782Least InformativeDirect
Disease Ontology (DO)disease of mental health0.0000000001345Moderately InformativeDirect
Disease Ontology (DO)neurodegenerative disease0.1564Moderately InformativeInherited
Disease Ontology (DO)schizophrenia0.000000000001129InformativeDirect
Disease Ontology (DO)epilepsy0.000001143InformativeDirect
Disease Ontology (DO)developmental disorder of mental health0.3823InformativeInherited
Disease Ontology (DO)lateral sclerosis0.000001206Highly InformativeDirect
Disease Ontology (DO)bipolar disorder0.000008229Highly InformativeDirect
Disease Ontology (DO)amyotrophic lateral sclerosis0.000008553Highly InformativeDirect
Disease Ontology (DO)focal epilepsy0.03645Highly InformativeInherited
Disease Ontology (DO)specific developmental disorder0.1619Highly InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the eye0.1307Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of central motor function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of higher mental function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Muscular hypotonia0.000399Moderately InformativeDirect
Phenotypic Abnormality (PA)Neurodevelopmental delay0.001763Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebrum0.00685Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal eye physiology0.04321Moderately InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0.05061Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal nervous system electrophysiology0.00636InformativeInherited
Phenotypic Abnormality (PA)Encephalopathy0.01804InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebral subcortex0.0429InformativeInherited
Phenotypic Abnormality (PA)Visual impairment0.1645InformativeInherited
Phenotypic Abnormality (PA)Hypoplasia of the corpus callosum0.000196Highly InformativeDirect
Phenotypic Abnormality (PA)Epileptic encephalopathy0.000385Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.00000503Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.08279Least InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.0000000000004223Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body composition0.008686Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.0000000000000589InformativeDirect
Mammalian Phenotype (MP)abnormal learning/memory/conditioning0.00001011InformativeDirect
Mammalian Phenotype (MP)abnormal sensory capabilities/reflexes/nociception0.0003327InformativeDirect
Mammalian Phenotype (MP)seizures0.0004606InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system electrophysiology0.0005708InformativeDirect
Mammalian Phenotype (MP)abnormal behavioral response to xenobiotic0.0006329InformativeDirect
Mammalian Phenotype (MP)decreased total tissue mass0.0009361InformativeDirect
Mammalian Phenotype (MP)abnormal emotion/affect behavior0.002321InformativeInherited
Mammalian Phenotype (MP)abnormal voluntary movement0.1388InformativeInherited
Mammalian Phenotype (MP)abnormal long term depression0.00000006153Highly InformativeDirect
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.0000001182Highly InformativeDirect
Mammalian Phenotype (MP)abnormal locomotor activation0.00000122Highly InformativeDirect
Mammalian Phenotype (MP)tonic-clonic seizures0.0003427Highly InformativeDirect
Mammalian Phenotype (MP)abnormal aggression-related behavior0.1071Highly InformativeInherited
Mammalian Phenotype (MP)abnormal response to novelty0.1447Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.002516Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.04242Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.7708Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.07957Moderately InformativeInherited
Worm Phenotype (WP)organism stress response variant0.1118Moderately InformativeInherited
Worm Phenotype (WP)fat content variant0.0002354InformativeDirect
Worm Phenotype (WP)chemosensory response variant0.0007761InformativeDirect
Worm Phenotype (WP)organism temperature response variant0.05285InformativeInherited
Worm Phenotype (WP)aqueous positive chemotaxis variant0.0000009906Highly InformativeDirect
Worm Phenotype (WP)positive chemotaxis defective0.000001675Highly InformativeDirect
Worm Phenotype (WP)thermotaxis variant0.00001391Highly InformativeDirect
Worm Phenotype (WP)pharyngeal pumping rate variant0.0002971Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)neurophysiology defective0.0000002047InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)embryonic stage0.1611Moderately InformativeInherited
Xenopus DEvelopment stage (XDE)tailbud stage0.07921InformativeInherited
Xenopus DEvelopment stage (XDE)NF stage 35 and 360.00009106Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases0.2811Moderately InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0InformativeDirect
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups0InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases1InformativeInherited
Enzyme Commission (EC)Hydro-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular transferases1InformativeInherited
Enzyme Commission (EC)Acting on polysaccharides0Highly InformativeDirect
Enzyme Commission (EC)Transferring other groups0.3435Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
DomainSignal0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 292 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Periplasmic binding protein-like II domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]