SUPERFAMILY 1.75 HMM library and genome assignments server

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Phosphate binding protein-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   Periplasmic binding protein-like II [ 53849]
Superfamily:   Periplasmic binding protein-like II [ 53850] (3)
Family:   Phosphate binding protein-like [ 53851] (40)


Family statistics
Genomes (3,138) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 43,518 340,414 128
Proteins 43,383 339,826 128


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases1Least InformativeInherited
Enzyme Commission (EC)Lyases0.06758Least InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Hydro-lyases1Moderately InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Acting on polysaccharides0InformativeDirect
Enzyme Commission (EC)Pentosyltransferases0InformativeDirect
Enzyme Commission (EC)Intramolecular transferases (mutases)1InformativeInherited

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.0007782Least InformativeDirect
Disease Ontology (DO)disease of mental health0.0000000001345Moderately InformativeDirect
Disease Ontology (DO)neurodegenerative disease0.1564Moderately InformativeInherited
Disease Ontology (DO)schizophrenia0.000000000001129InformativeDirect
Disease Ontology (DO)epilepsy0.000001143InformativeDirect
Disease Ontology (DO)developmental disorder of mental health0.3823InformativeInherited
Disease Ontology (DO)lateral sclerosis0.000001206Highly InformativeDirect
Disease Ontology (DO)bipolar disorder0.000008229Highly InformativeDirect
Disease Ontology (DO)amyotrophic lateral sclerosis0.000008553Highly InformativeDirect
Disease Ontology (DO)focal epilepsy0.03645Highly InformativeInherited
Disease Ontology (DO)specific developmental disorder0.1619Highly InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Epileptic encephalopathy0.0003677InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000005016Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.08297Least InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.0000000000004217Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body composition0.008743Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.00000000000005881InformativeDirect
Mammalian Phenotype (MP)abnormal learning/memory/conditioning0.00001015InformativeDirect
Mammalian Phenotype (MP)abnormal sensory capabilities/reflexes/nociception0.0003356InformativeDirect
Mammalian Phenotype (MP)seizures0.0004637InformativeDirect
Mammalian Phenotype (MP)abnormal behavioral response to xenobiotic0.0006378InformativeDirect
Mammalian Phenotype (MP)decreased total tissue mass0.0009451InformativeDirect
Mammalian Phenotype (MP)abnormal emotion/affect behavior0.002337InformativeInherited
Mammalian Phenotype (MP)abnormal voluntary movement0.1389InformativeInherited
Mammalian Phenotype (MP)abnormal long term depression0.00000006166Highly InformativeDirect
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.0000001181Highly InformativeDirect
Mammalian Phenotype (MP)abnormal locomotor activation0.000001227Highly InformativeDirect
Mammalian Phenotype (MP)tonic-clonic seizures0.0003446Highly InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system electrophysiology0.0005733Highly InformativeDirect
Mammalian Phenotype (MP)abnormal aggression-related behavior0.1072Highly InformativeInherited
Mammalian Phenotype (MP)abnormal response to novelty0.1448Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.0205Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.1019Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.726Least InformativeInherited
Worm Phenotype (WP)chemical response variant0.0001459Moderately InformativeDirect
Worm Phenotype (WP)feeding behavior variant0.05428Moderately InformativeInherited
Worm Phenotype (WP)chemotaxis variant0.00000165InformativeDirect
Worm Phenotype (WP)fat content variant0.0002058InformativeDirect
Worm Phenotype (WP)pharyngeal pumping variant0.0007511InformativeDirect
Worm Phenotype (WP)organism stress response variant0.07409InformativeInherited
Worm Phenotype (WP)aqueous positive chemotaxis variant0.0000009672Highly InformativeDirect
Worm Phenotype (WP)positive chemotaxis defective0.000001719Highly InformativeDirect
Worm Phenotype (WP)isothermal tracking behavior variant0.00003574Highly InformativeDirect
Worm Phenotype (WP)pharyngeal pumping irregular0.0001262Highly InformativeDirect
Worm Phenotype (WP)pharyngeal pumping rate variant0.0002207Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)resistance to chemicals0Least InformativeDirect
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)neurophysiology defective0.0000001552InformativeDirect
Fly Phenotype (FP)sensory perception defective0.01204InformativeInherited

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)nervous system0.04171Least InformativeInherited
Fly Anatomy (FA)embryo0.4907Least InformativeInherited
Fly Anatomy (FA)larva0.798Least InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.08867Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval nervous system0.1082Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval peripheral nervous system0.01671InformativeInherited
Fly Anatomy (FA)cell component0.0281InformativeInherited
Fly Anatomy (FA)embryonic/larval neuromuscular junction0.0004134Highly InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus DEvelopment stage (XDE)embryonic stage0.1573Moderately InformativeInherited
Xenopus DEvelopment stage (XDE)tailbud stage0.07858InformativeInherited
Xenopus DEvelopment stage (XDE)NF stage 35 and 360.00007965Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Lyases0.288Moderately InformativeInherited
Enzyme Commission (EC)Acting on ester bonds1Moderately InformativeInherited
Enzyme Commission (EC)Isomerases1Moderately InformativeInherited
Enzyme Commission (EC)Glycosyltransferases0InformativeDirect
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups0InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases1InformativeInherited
Enzyme Commission (EC)Hydro-lyases1InformativeInherited
Enzyme Commission (EC)Intramolecular transferases1InformativeInherited
Enzyme Commission (EC)Acting on polysaccharides0Highly InformativeDirect
Enzyme Commission (EC)Transferring other groups0.3467Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 292 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Periplasmic binding protein-like II domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]