SUPERFAMILY 1.73 HMM library and genome assignments server


Ubiquitin-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (334)
  Mainly antiparallel beta sheets (segregated alpha and beta regions)
Fold:   beta-Grasp (ubiquitin-like) [ 54235] (13)
  core: beta(2)-alpha-beta(2); mixed beta-sheet 2143
Superfamily:   Ubiquitin-like [ 54236] (7)
Families:   Ubiquitin-related [ 54237] (38)
  Pfam 00240
  UBX domain [ 54250] (5)
  Pfam 00789
  GABARAP-like [ 54253] (3)
  intracellular membrane trafficking and fusion proteins
  First domain of FERM [ 54256] (6)
  Ras-binding domain, RBD [ 54263] (13)
  contains Pfam 00788 and Pfam 02196
  BM-002-like [ 75362] (3)
  Pfam 03671; UPF0185; this family comprises small uncharacterized proteins including human protein BM-002
  APG12-like [ 142972]
  Pfam 04110


Superfamily statistics
Genomes (292) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 23,612 10,893 138
Proteins 20,238 8,751 137


Functional annotation
General category General
Detailed category General

Function annotation of SCOP domain superfamilies

Jump to [ Top of page · SCOP classification · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 78 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Ubiquitin-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 78 hidden Markov models representing the Ubiquitin-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]