SUPERFAMILY 1.75 HMM library and genome assignments server

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Nicotinate/Quinolinate PRTase N-terminal domain-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   alpha/beta-Hammerhead [ 54664] (5)
Superfamily:   Nicotinate/Quinolinate PRTase N-terminal domain-like [ 54675] (2)
Families:   NadC N-terminal domain-like [ 54676] (4)
  Monomeric nicotinate phosphoribosyltransferase N-terminal domain-like [ 110907]


Superfamily statistics
Genomes (2,973) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 5,366 28,970 9
Proteins 5,364 28,945 9


Functional annotation
General category Metabolism
Detailed category Coenzyme metabolism and transport

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular aromatic compound metabolic process 0.00000000001199 Least Informative Direct
Biological Process (BP) biosynthetic process 0.000055 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.00000000007663 Least Informative Direct
Biological Process (BP) primary metabolic process 0.000004846 Least Informative Direct
Biological Process (BP) single-organism metabolic process 0.0000000008158 Least Informative Direct
Biological Process (BP) single-organism cellular process 0.0001506 Least Informative Direct
Biological Process (BP) heterocycle metabolic process 0.000000000009832 Least Informative Direct
Biological Process (BP) organic cyclic compound metabolic process 0.00000000004319 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.00000001232 Least Informative Direct
Biological Process (BP) response to stimulus 0.2322 Least Informative Inherited
Biological Process (BP) nucleoside phosphate metabolic process 0 Moderately Informative Direct
Biological Process (BP) heterocycle biosynthetic process 0.0000002343 Moderately Informative Direct
Biological Process (BP) aromatic compound biosynthetic process 0.0000001069 Moderately Informative Direct
Biological Process (BP) cofactor metabolic process 0 Moderately Informative Direct
Biological Process (BP) organophosphate biosynthetic process 0.0000000001313 Moderately Informative Direct
Biological Process (BP) organic cyclic compound biosynthetic process 0.0000008229 Moderately Informative Direct
Biological Process (BP) oxidoreduction coenzyme metabolic process 0 Informative Direct
Biological Process (BP) response to oxidative stress 0.00001653 Informative Direct
Biological Process (BP) coenzyme biosynthetic process 0.0001325 Informative Direct
Biological Process (BP) nucleotide biosynthetic process 0.0003408 Informative Direct
Biological Process (BP) pyridine-containing compound metabolic process 0 Informative Direct
Biological Process (BP) NAD metabolic process 0 Highly Informative Direct
Biological Process (BP) pyridine-containing compound biosynthetic process 0 Highly Informative Direct
Molecular Function (MF) transferase activity 8.27e-16 Least Informative Direct
Molecular Function (MF) transferase activity, transferring glycosyl groups 0 Informative Direct
Molecular Function (MF) transferase activity, transferring pentosyl groups 0 Highly Informative Direct

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosyltransferases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processPyridine nucleotide biosynthesis0Highly InformativeDirect
Post-translational modificationTransferase0Least InformativeDirect
Post-translational modificationGlycosyltransferase0.0001488InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 9 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Nicotinate/Quinolinate PRTase N-terminal domain-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 9 hidden Markov models representing the Nicotinate/Quinolinate PRTase N-terminal domain-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]