SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Elongation factor Ts (EF-Ts), dimerisation domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   EF-Ts domain-like [ 54712] (2)
Superfamily:   Elongation factor Ts (EF-Ts), dimerisation domain [ 54713]
Families:   Elongation factor Ts (EF-Ts), dimerisation domain [ 54714]


Superfamily statistics
Genomes (2,891) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 5,124 28,162 6
Proteins 3,128 17,503 4


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) cellular nitrogen compound metabolic process 0.00006918 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.0006607 Least Informative Direct
Biological Process (BP) biosynthetic process 0.001467 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.07324 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.009022 Least Informative Inherited
Biological Process (BP) amide biosynthetic process 0.000000004718 Moderately Informative Direct
Biological Process (BP) peptide metabolic process 0.000001202 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.000001553 Moderately Informative Direct
Biological Process (BP) gene expression 0.000003703 Moderately Informative Direct
Molecular Function (MF) binding 0.02342 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.00004416 Moderately Informative Direct
Molecular Function (MF) RNA binding 0.0000001217 Informative Direct
Cellular Component (CC) cytoplasmic part 0.0000008226 Least Informative Direct
Cellular Component (CC) intracellular membrane-bounded organelle 0.00156 Least Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Cellular componentCytoplasm0Least InformativeDirect
DomainTransit peptide0.0005294Moderately InformativeDirect
Post-translational modificationElongation factor0Highly InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR014039 SSF54713 Protein matches
Abstract

This entry represents the C-terminal dimerisation domain found primarily in EF-Tu (EF1A) proteins from bacteria, mitochondria and chloroplasts.

More information about these proteins can be found at Protein of the Month: Elongation Factors.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 5 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Elongation factor Ts (EF-Ts), dimerisation domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 5 hidden Markov models representing the Elongation factor Ts (EF-Ts), dimerisation domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]