SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Canonical RBD family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ferredoxin-like [ 54861] (59)
Superfamily:   RNA-binding domain, RBD [ 54928] (5)
Family:   Canonical RBD [ 54929] (67)


Family statistics
Genomes (488) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 15,913 44,917 131
Proteins 12,849 36,059 123


Enzyme Commission (EC)

(
show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0.00000001195Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0.000006192Least InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups0.000022Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0.01789Least InformativeInherited
Enzyme Commission (EC)Methyltransferases0.0000001778Moderately InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0.0196Moderately InformativeInherited
Enzyme Commission (EC)Histone-lysine N-methyltransferase0.00000000002592InformativeDirect
Enzyme Commission (EC)Exoribonucleases producing 5'-phosphomonoesters0.00000002223InformativeDirect
Enzyme Commission (EC)Cis-trans Isomerases1InformativeInherited
Enzyme Commission (EC)Polynucleotide adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Poly(A)-specific ribonuclease1.746e-16Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)myopathy1InformativeInherited
Disease Ontology (DO)ischemia0.2244Highly InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Y-linked inheritance0.0002807Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.4074Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.4255Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.4583Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the musculature0.463Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.6382Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.912Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal respiratory system morphology0.1937Moderately InformativeInherited
Phenotypic Abnormality (PA)Behavioral abnormality0.2239Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal skeletal muscle morphology0.2613Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of central motor function0.3149Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating metabolite concentration0.5372Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0.5433Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal peripheral nervous system morphology0.6264Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper respiratory tract0.00317InformativeInherited
Phenotypic Abnormality (PA)Impairment in personality functioning0.008931InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating protein level0.02589InformativeInherited
Phenotypic Abnormality (PA)Muscle weakness0.03581InformativeInherited
Phenotypic Abnormality (PA)Neurological speech impairment0.2052InformativeInherited
Phenotypic Abnormality (PA)Abnormality of reproductive system physiology0.4269InformativeInherited
Phenotypic Abnormality (PA)Abnormal synaptic transmission at the neuromuscular junction1InformativeInherited
Phenotypic Abnormality (PA)Motor neuron atrophy0.0000002458Highly InformativeDirect
Phenotypic Abnormality (PA)Fatigable weakness of swallowing muscles0.0000004375Highly InformativeDirect
Phenotypic Abnormality (PA)Fatigable weakness of respiratory muscles0.00001194Highly InformativeDirect
Phenotypic Abnormality (PA)Paralysis0.0001182Highly InformativeDirect
Phenotypic Abnormality (PA)Agitation0.0001464Highly InformativeDirect
Phenotypic Abnormality (PA)Decreased fertility in males0.0001761Highly InformativeDirect
Phenotypic Abnormality (PA)Anxiety0.0005491Highly InformativeDirect
Phenotypic Abnormality (PA)Azoospermia0.001239Highly InformativeInherited
Phenotypic Abnormality (PA)Specific learning disability0.01434Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal larynx physiology0.0171Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral physiology0.01888Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.3085Least InformativeInherited
Mammalian Phenotype (MP)nervous system phenotype0.9696Least InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.5564Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.8573Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron differentiation0.2627InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.000000000002461Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.000005875Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.000322Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.002856Least InformativeInherited
Worm Phenotype (WP)larval arrest0.3691Least InformativeInherited
Worm Phenotype (WP)progeny variant0.8632Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.9602Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.000000001344Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.00008099Moderately InformativeDirect
Worm Phenotype (WP)cell type morphology variant0.01205Moderately InformativeInherited
Worm Phenotype (WP)movement variant0.0222Moderately InformativeInherited
Worm Phenotype (WP)organism stress response variant0.3101Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.3224Moderately InformativeInherited
Worm Phenotype (WP)germ cell development variant0.9878Moderately InformativeInherited
Worm Phenotype (WP)cell death variant1Moderately InformativeInherited
Worm Phenotype (WP)RNA expression variant0.000000004562InformativeDirect
Worm Phenotype (WP)vulva morphology variant0.0000008396InformativeDirect
Worm Phenotype (WP)sick0.0000009523InformativeDirect
Worm Phenotype (WP)brood size variant0.00004646InformativeDirect
Worm Phenotype (WP)cell number increased0.001242InformativeInherited
Worm Phenotype (WP)egg laying variant0.0638InformativeInherited
Worm Phenotype (WP)organism pathogen response variant0.07768InformativeInherited
Worm Phenotype (WP)oocyte morphology variant0.1747InformativeInherited
Worm Phenotype (WP)cell proliferation increased3.135e-16Highly InformativeDirect
Worm Phenotype (WP)intestinal development variant0.00000000000221Highly InformativeDirect
Worm Phenotype (WP)neurite development variant0.000003179Highly InformativeDirect
Worm Phenotype (WP)no induction of antimicrobial peptide expression after infection0.00002375Highly InformativeDirect
Worm Phenotype (WP)sexually dimorphic development variant0.00003029Highly InformativeDirect
Worm Phenotype (WP)developmental morphology variant0.0001108Highly InformativeDirect
Worm Phenotype (WP)germline proliferation variant0.0007865Highly InformativeDirect
Worm Phenotype (WP)embryonic arrest0.0149Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.003022Least InformativeInherited

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0.0000000000001589Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0.0000003106Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0.000007189Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0.0001625Least InformativeDirect
Xenopus ANatomical entity (XAN)anatomical cluster0.0001753Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0.001049Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.01151Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.1474Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.0000000000009335Moderately InformativeDirect
Xenopus ANatomical entity (XAN)testis0.000000131Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0.000007762Moderately InformativeDirect
Xenopus ANatomical entity (XAN)musculoskeletal system0.00001198Moderately InformativeDirect
Xenopus ANatomical entity (XAN)multi-tissue structure0.00003506Moderately InformativeDirect
Xenopus ANatomical entity (XAN)alimentary system0.00003666Moderately InformativeDirect
Xenopus ANatomical entity (XAN)tail region0.0002082Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0.0003299Moderately InformativeDirect
Xenopus ANatomical entity (XAN)viscus0.002079Moderately InformativeInherited
Xenopus ANatomical entity (XAN)brain0.003492Moderately InformativeInherited
Xenopus ANatomical entity (XAN)germ cell0.03823Moderately InformativeInherited
Xenopus ANatomical entity (XAN)anatomical entity in vitro0InformativeDirect
Xenopus ANatomical entity (XAN)endocrine system0.000000000001651InformativeDirect
Xenopus ANatomical entity (XAN)endomesoderm0.00000003215InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0.000005885InformativeDirect
Xenopus ANatomical entity (XAN)liver and biliary system0.0000169InformativeDirect
Xenopus ANatomical entity (XAN)limb0.0001626InformativeDirect
Xenopus ANatomical entity (XAN)spinal cord0.0002664InformativeDirect
Xenopus ANatomical entity (XAN)tail0.0003203InformativeDirect
Xenopus ANatomical entity (XAN)solid compound organ0.0004547InformativeDirect
Xenopus ANatomical entity (XAN)eye0.0005517InformativeDirect
Xenopus ANatomical entity (XAN)neuroectoderm0.04508InformativeInherited
Xenopus ANatomical entity (XAN)thymus0.000000000001174Highly InformativeDirect
Xenopus ANatomical entity (XAN)blastopore lip0.00001029Highly InformativeDirect
Xenopus ANatomical entity (XAN)hindbrain0.000317Highly InformativeDirect
Xenopus ANatomical entity (XAN)vegetal hemisphere0.003453Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.00004022Least InformativeDirect
Xenopus DEvelopment stage (XDE)unspecified stage0.00008094Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)NF stage 660.00003506InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)seed0.0000004931Least InformativeDirect
Plant ANatomical entity (PAN)shoot apex0.000001725Least InformativeDirect
Plant ANatomical entity (PAN)branch0.000004142Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0.00003465Least InformativeDirect
Plant ANatomical entity (PAN)stalk0.00004228Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0.00005758Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0.00007026Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0.00008464Least InformativeDirect
Plant ANatomical entity (PAN)petal0.0002254Least InformativeDirect
Plant ANatomical entity (PAN)androecium0.0002946Least InformativeDirect
Plant ANatomical entity (PAN)root0.0006504Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0.0008448Least InformativeDirect
Plant ANatomical entity (PAN)sepal0.0008994Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0.01814Least InformativeInherited
Plant ANatomical entity (PAN)vascular leaf0.7638Least InformativeInherited
Plant ANatomical entity (PAN)bud0.01703Highly InformativeInherited
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0.000002108Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0.000004237Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0.00001015Least InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0.0001038Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.08217Least InformativeInherited
Enzyme Commission (EC)Transferases0.2117Least InformativeInherited
Enzyme Commission (EC)Isomerases0.0000000001247Moderately InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0.00001779Moderately InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups0.00008862Moderately InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0.02409Moderately InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.2346Moderately InformativeInherited
Enzyme Commission (EC)Methyltransferases0.000000498InformativeDirect
Enzyme Commission (EC)Acting on ATP; involved in cellular and subcellular movement0.01106InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases0.01701InformativeInherited
Enzyme Commission (EC)Exoribonucleases producing 5'-phosphomonoesters0.00000001657Highly InformativeDirect
Enzyme Commission (EC)Cis-trans isomerases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Post-translational modificationRNA-binding0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 194 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a RNA-binding domain, RBD domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]