SUPERFAMILY 1.75 HMM library and genome assignments server

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EF-G/eEF-2 domains III and V family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ferredoxin-like [ 54861] (59)
Superfamily:   EF-G C-terminal domain-like [ 54980] (3)
Family:   EF-G/eEF-2 domains III and V [ 54981] (2)


Family statistics
Genomes (2,999) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 5,832 29,149 17
Proteins 3,799 19,832 9


Gene Ontology (high-coverage)

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show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0 Least Informative Direct
Biological Process (BP) primary metabolic process 0.000000000001221 Least Informative Direct
Biological Process (BP) macromolecule metabolic process 0.000000000003962 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.00000000004171 Least Informative Direct
Biological Process (BP) single-organism cellular process 1 Least Informative Inherited
Biological Process (BP) gene expression 0 Moderately Informative Direct
Biological Process (BP) cellular nitrogen compound biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) cellular amide metabolic process 0 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0 Moderately Informative Direct
Biological Process (BP) macromolecular complex subunit organization 0.0000000000006925 Moderately Informative Direct
Biological Process (BP) cellular protein metabolic process 0.000000000003148 Moderately Informative Direct
Biological Process (BP) organelle organization 0.0002715 Moderately Informative Direct
Biological Process (BP) translation 0 Informative Direct
Biological Process (BP) single-organism organelle organization 0.000000135 Informative Direct
Biological Process (BP) mitochondrial gene expression 0 Highly Informative Direct
Biological Process (BP) cellular component disassembly 0 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) binding 0.02658 Least Informative Inherited
Molecular Function (MF) heterocyclic compound binding 0.000000000000001922 Moderately Informative Direct
Molecular Function (MF) organic cyclic compound binding 0.000000000000004405 Moderately Informative Direct
Molecular Function (MF) anion binding 0.02999 Moderately Informative Inherited
Molecular Function (MF) small molecule binding 0.03225 Moderately Informative Inherited
Molecular Function (MF) nucleoside-triphosphatase activity 0 Informative Direct
Molecular Function (MF) RNA binding 0 Informative Direct
Molecular Function (MF) nucleotide binding 0.001149 Informative Inherited
Molecular Function (MF) carbohydrate derivative binding 0.004261 Informative Inherited
Molecular Function (MF) translation factor activity, RNA binding 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.01667 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 0.7301 Least Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)Acting on GTP; involved in cellular and subcellula0Highly InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Biological processAntibiotic resistance0.0000003309InformativeDirect
Cellular componentMembrane0Least InformativeDirect
Cellular componentCell membrane0Moderately InformativeDirect
Cellular componentMitochondrion0Moderately InformativeDirect
Cellular componentCell inner membrane0InformativeDirect
DomainTransit peptide0Moderately InformativeDirect
Molecular functionNucleotide-binding0Least InformativeDirect
Molecular functionGTP-binding0InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationElongation factor0Highly InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 11 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a EF-G C-terminal domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]