SUPERFAMILY 1.75 HMM library and genome assignments server

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eEF-1beta-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Ferredoxin-like [ 54861] (59)
Superfamily:   eEF-1beta-like [ 54984]
Families:   eEF-1beta-like [ 54985] (2)


Superfamily statistics
Genomes (630) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 1,241 3,350 5
Proteins 1,235 3,337 5


Functional annotation
General category Information
Detailed category Translation

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) biosynthetic process 0.0002012 Least Informative Direct
Biological Process (BP) cellular nitrogen compound metabolic process 0.0009612 Least Informative Direct
Biological Process (BP) organonitrogen compound metabolic process 0.01662 Least Informative Inherited
Biological Process (BP) primary metabolic process 0.2743 Least Informative Inherited
Biological Process (BP) macromolecule metabolic process 0.03183 Least Informative Inherited
Biological Process (BP) amide biosynthetic process 0.00000000005139 Moderately Informative Direct
Biological Process (BP) peptide metabolic process 0.00000000006705 Moderately Informative Direct
Biological Process (BP) cellular macromolecule biosynthetic process 0.00000009037 Moderately Informative Direct
Biological Process (BP) gene expression 0.0000002754 Moderately Informative Direct
Molecular Function (MF) binding 0.0385 Least Informative Inherited
Molecular Function (MF) nucleic acid binding 0.000006942 Moderately Informative Direct
Molecular Function (MF) RNA binding 0.000000003686 Informative Direct
Molecular Function (MF) translation factor activity, RNA binding 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.0003774 Least Informative Direct
Cellular Component (CC) protein complex 0.0191 Least Informative Inherited

Document: GO annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processProtein biosynthesis0InformativeDirect
Post-translational modificationElongation factor0Highly InformativeDirect
Post-translational modificationAcetylation0.0000000006817Least InformativeDirect
Post-translational modificationPhosphoprotein0.0004037Least InformativeDirect

Document: KW annotation of SCOP domains

InterPro annotation
Cross references IPR014038 SSF54984 Protein matches
Abstract

This entry represents the guanine nucleotide exchange domain of the beta (EF-1beta, also known as EF1B-alpha) and delta (EF-1delta, also known as EF1B-beta) chains of EF1B proteins from eukaryotes and archaea. The beta and delta chains have exchange activity, which mainly resides in their homologous guanine nucleotide exchange domains, found in the C-terminal region of the peptides. Their N-terminal regions may be involved in interactions with the gamma chain (EF-1gamma).

More information about these proteins can be found at Protein of the Month: Elongation Factors.


InterPro database


PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a eEF-1beta-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the eEF-1beta-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Gene Ontology (high-coverage) · UniProtKB KeyWords (KW) · Internal database links ]