SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


beta-N-acetylhexosaminidase-like domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   Zincin-like [ 55485] (2)
Superfamily:   beta-N-acetylhexosaminidase-like domain [ 55545] (3)
Families:   beta-N-acetylhexosaminidase domain [ 55546] (4)
  alpha-D-glucuronidase, N-terminal domain [ 82737]
  Hyaluronidase N-terminal domain-like [ 143618] (2)


Superfamily statistics
Genomes (955) Uniprot 2017_06 genome PDB chains (SCOP 1.75)
Domains 2,597 18,147 23
Proteins 2,585 18,051 23


Functional annotation
General category Metabolism
Detailed category Other enzymes

Document:
Function annotation of SCOP domain superfamilies

Gene Ontology (high-coverage)

(show details)
GO term FDR (all) SDFO level Annotation (direct or inherited)
Biological Process (BP) macromolecule metabolic process 0.02276 Least Informative Inherited
Biological Process (BP) organonitrogen compound metabolic process 0.2829 Least Informative Inherited
Biological Process (BP) primary metabolic process 1 Least Informative Inherited
Biological Process (BP) carbohydrate derivative metabolic process 0.000000000005826 Moderately Informative Direct
Biological Process (BP) carbohydrate metabolic process 0.00003442 Moderately Informative Direct
Biological Process (BP) organic substance catabolic process 0.0001095 Moderately Informative Direct
Biological Process (BP) cellular protein modification process 0.2453 Moderately Informative Inherited
Biological Process (BP) carbohydrate derivative catabolic process 0.00002344 Informative Direct
Biological Process (BP) glycoprotein metabolic process 0.0000002468 Highly Informative Direct
Biological Process (BP) aminoglycan catabolic process 0.0001622 Highly Informative Direct
Biological Process (BP) amino sugar metabolic process 0.0005142 Highly Informative Direct
Molecular Function (MF) hydrolase activity 0 Least Informative Direct
Molecular Function (MF) hydrolase activity, acting on glycosyl bonds 0 Informative Direct
Molecular Function (MF) hydrolase activity, hydrolyzing O-glycosyl compounds 0 Highly Informative Direct
Cellular Component (CC) cytoplasmic part 0.9807 Least Informative Inherited
Cellular Component (CC) intracellular membrane-bounded organelle 1 Least Informative Inherited
Cellular Component (CC) vacuole 0.000001851 Moderately Informative Direct
Cellular Component (CC) lytic vacuole 0.05849 Informative Inherited

Document: GO annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Glycosidases, i.e. enzymes hydrolyzing O- and S-gl0Moderately InformativeDirect

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Biological processCarbohydrate metabolism0Moderately InformativeDirect
Biological processPolysaccharide degradation0InformativeDirect
Cellular componentSecreted0.0000000007693Moderately InformativeDirect
Cellular componentLysosome0InformativeDirect
DomainSignal0Least InformativeDirect
Post-translational modificationHydrolase0Least InformativeDirect
Post-translational modificationGlycosidase0InformativeDirect
Post-translational modificationGlycoprotein0Least InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a beta-N-acetylhexosaminidase-like domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 8 hidden Markov models representing the beta-N-acetylhexosaminidase-like domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Gene Ontology (high-coverage) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]