SUPERFAMILY 1.75 HMM library and genome assignments server

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C-type lectin domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a+b) [ 53931] (376)
Fold:   C-type lectin-like [ 56435]
Superfamily:   C-type lectin-like [ 56436] (8)
Family:   C-type lectin domain [ 56437] (28)


Family statistics
Genomes (74) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,289 5,778 88
Proteins 2,285 5,729 88


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)disease by infectious agent0.0004202Moderately InformativeDirect
Disease Ontology (DO)connective tissue disease0.1644Moderately InformativeInherited
Disease Ontology (DO)lower respiratory tract disease0.7755Moderately InformativeInherited
Disease Ontology (DO)vasculitis0.0006121InformativeDirect
Disease Ontology (DO)arthritis0.003222InformativeInherited
Disease Ontology (DO)opportunistic mycosis0.000175Highly InformativeDirect
Disease Ontology (DO)rheumatoid arthritis0.0004103Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the respiratory system0.06003Moderately InformativeInherited
Phenotypic Abnormality (PA)Functional respiratory abnormality0.4187InformativeInherited
Phenotypic Abnormality (PA)Cough0.0009879Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)immune system phenotype0.000000001561Least InformativeDirect
Mammalian Phenotype (MP)hematopoietic system phenotype0.00006465Least InformativeDirect
Mammalian Phenotype (MP)abnormal homeostasis0.03287Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.9599Least InformativeInherited
Mammalian Phenotype (MP)mortality/aging0.9706Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype1Least InformativeInherited
Mammalian Phenotype (MP)altered susceptibility to infection0.000000000001951Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal induced morbidity/mortality0.000008137Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal protein level0.0005016Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal leukocyte physiology0.4125Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin morphology0.6172Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0.8129Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.9878Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell migration0.1132InformativeInherited
Mammalian Phenotype (MP)abnormal lymph node morphology0.1299InformativeInherited
Mammalian Phenotype (MP)hemorrhage0.5725InformativeInherited
Mammalian Phenotype (MP)abnormal cervical lymph node morphology0.0004643Highly InformativeDirect
Mammalian Phenotype (MP)abnormal leukocyte adhesion0.01746Highly InformativeInherited
Mammalian Phenotype (MP)abnormal cellular extravasation0.08824Highly InformativeInherited
Mammalian Phenotype (MP)abnormal granulocyte physiology0.09527Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)sterile progeny0.0008088Least InformativeDirect
Worm Phenotype (WP)organism environmental stimulus response variant1Least InformativeInherited
Worm Phenotype (WP)organism segment morphology variant1Moderately InformativeInherited
Worm Phenotype (WP)male morphology variant0.2483InformativeInherited
Worm Phenotype (WP)organism pathogen response variant0.8108InformativeInherited
Worm Phenotype (WP)sensillum morphology variant0.9789InformativeInherited
Worm Phenotype (WP)male ray morphology variant0.03563Highly InformativeInherited
Worm Phenotype (WP)pathogen susceptibility increased0.1236Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 124 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a C-type lectin-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]