SUPERFAMILY 1.75 HMM library and genome assignments server

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LDL receptor-like module family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Small proteins [ 56992] (90)
Fold:   LDL receptor-like module [ 57423]
Superfamily:   LDL receptor-like module [ 57424]
Family:   LDL receptor-like module [ 57425] (6)


Family statistics
Genomes (45) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 105 309 10
Proteins 65 186 9


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on peptide bonds (peptide hydrolases)0Least InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the eye0.5262Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the immune system0.675Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of immune system physiology0.386Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of complement system0.00003591InformativeDirect
Phenotypic Abnormality (PA)Recurrent infections0.2597InformativeInherited
Phenotypic Abnormality (PA)Abnormal fundus morphology0.2914InformativeInherited
Phenotypic Abnormality (PA)Recurrent Neisserial infections0.000003055Highly InformativeDirect
Phenotypic Abnormality (PA)Yellow/white lesions of the retina0.0007901Highly InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.02321Least InformativeInherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.2094Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.5979Least InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.3188Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal ion homeostasis0.01945InformativeInherited
Mammalian Phenotype (MP)abnormal testis morphology0.5263InformativeInherited
Mammalian Phenotype (MP)amyloidosis0.004721Highly InformativeInherited
Mammalian Phenotype (MP)nervous system inclusion bodies0.0079Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.6199Least InformativeInherited
Worm Phenotype (WP)movement variant0.8719Moderately InformativeInherited
Worm Phenotype (WP)locomotion reduced0.07385InformativeInherited
Worm Phenotype (WP)paralyzed0.0007903Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0.2338Least InformativeInherited
Fly Anatomy (FA)epithelium0.1873Moderately InformativeInherited
Fly Anatomy (FA)late embryo0.6205Moderately InformativeInherited
Fly Anatomy (FA)embryonic/larval tracheal system0.03102InformativeInherited
Fly Anatomy (FA)epithelial tube0.2338InformativeInherited
Fly Anatomy (FA)primary trachea0.002404Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval trachea0.004722Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)multi-tissue structure0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0.9488Least InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system0.3298Moderately InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.5839Moderately InformativeInherited
Xenopus ANatomical entity (XAN)hindgut0.0006416Highly InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.00000006839Least InformativeDirect
Enzyme Commission (EC)Acting on peptide bonds (peptidases)0Moderately InformativeDirect
Enzyme Commission (EC)Serine endopeptidases0InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 16 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a LDL receptor-like module domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]